Phyllostomus hastatus (greater spear-nosed bat): 123806900
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Entry
123806900 CDS
T07912
Symbol
PDHA2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
phas
Phyllostomus hastatus (greater spear-nosed bat)
Pathway
phas00010
Glycolysis / Gluconeogenesis
phas00020
Citrate cycle (TCA cycle)
phas00620
Pyruvate metabolism
phas00785
Lipoic acid metabolism
phas01100
Metabolic pathways
phas01200
Carbon metabolism
phas01210
2-Oxocarboxylic acid metabolism
phas04066
HIF-1 signaling pathway
phas04922
Glucagon signaling pathway
phas05230
Central carbon metabolism in cancer
phas05415
Diabetic cardiomyopathy
Module
phas_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
phas00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
123806900 (PDHA2)
00020 Citrate cycle (TCA cycle)
123806900 (PDHA2)
00620 Pyruvate metabolism
123806900 (PDHA2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
123806900 (PDHA2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
123806900 (PDHA2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
123806900 (PDHA2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
123806900 (PDHA2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
123806900 (PDHA2)
Enzymes [BR:
phas01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
123806900 (PDHA2)
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Motif
Pfam:
E1_dh
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
123806900
NCBI-ProteinID:
XP_045676310
LinkDB
All DBs
Position
Unknown
AA seq
391 aa
AA seq
DB search
MKKMLVAAVSRVLSGVSQKPANRVLVASCNYSNDATFEIKKCDLHRLEEGPPVTTVLTRQ
DGLKYYKTMQTIRRMELKADQLYKQKFIRGFCHLCDGQEACYVGLEAGVNPTDHIITSYR
SHGFCYTRGLSIRSILAELTGRRGGCAKGKGGSMHMYCKNFYGGNGIVGAQGPLGAGISL
ASKYKGSNEICLTVYGDGAANQGQIAEAYNMAALWKLPCIFICENNRYGMGTAITRAAAS
TDYYKRGNFMPGLRVDGMDVLCVREATKFAADYCRSGKGPIVMELQTYRYHGHSMSDPGV
SYRTREEIQNVRGKSDPIMLLQDKIVNSHLASVEELKEIDVEVRKEIDDAAEFATTDPEP
ALEEIAHHIYSDNPPFEVRGANQWVKFKSIS
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgaagaagatgctcgtagctgctgtgtcccgcgtgttgtccggtgtctcccagaagcct
gctaacagagtgctggtagcatcctgtaactattcaaatgacgctacatttgaaattaag
aaatgtgatcttcatcggttggaagaaggccctcctgtcacaacggtgctcactcggcag
gatgggctcaaatactacaagacgatgcagactattcgccgaatggaactgaaggcagat
cagctgtataaacagaaattcattcgtggcttctgtcacttgtgtgatggtcaggaggct
tgctatgtgggcctggaggccggggtaaatcccaccgaccacatcatcacatcctaccgg
tctcacggcttttgctacactcgtggactctctattaggtcaattcttgcagagctgaca
ggacgaagaggaggctgtgctaaagggaaaggaggatcgatgcatatgtattgtaagaac
ttctacgggggcaatggcattgtgggcgcacagggacccctgggagccgggatttcactg
gcctctaaatataaaggaagcaacgagatctgcttgactgtgtatggggatggtgctgcc
aatcagggtcagatagctgaagcttacaatatggcagccttgtggaaattaccatgtatt
ttcatctgtgagaataaccgctatggaatgggaacagctattacgagagcagcagccagc
actgattactacaagagaggaaattttatgcctggactaagggtagacggaatggatgtg
ctgtgtgttcgggaggcaactaagtttgcagctgattattgtagatctggaaaggggccc
atagtgatggagctccagacatatcgttatcatggacacagtatgagtgatcctggagtc
agttaccgtacccgagaagaaattcaaaatgtaagaggtaagagtgatccaattatgctt
ctccaagataaaatagtaaacagccaccttgccagtgttgaagaactgaaggaaattgat
gttgaagtgaggaaagaaattgatgatgcagccgagtttgctacaactgatcctgaacca
gctttggaagaaatagcccatcatatctacagtgacaatccaccctttgaagttcgtgga
gcaaatcagtgggtcaagtttaagtccatcagttaa
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