Phyllostomus hastatus (greater spear-nosed bat): 123822289
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Entry
123822289 CDS
T07912
Symbol
ACACB
Name
(RefSeq) acetyl-CoA carboxylase 2 isoform X1
KO
K01946
acetyl-CoA carboxylase / biotin carboxylase 2 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
phas
Phyllostomus hastatus (greater spear-nosed bat)
Pathway
phas00061
Fatty acid biosynthesis
phas00620
Pyruvate metabolism
phas00640
Propanoate metabolism
phas01100
Metabolic pathways
phas04152
AMPK signaling pathway
phas04910
Insulin signaling pathway
phas04920
Adipocytokine signaling pathway
phas04922
Glucagon signaling pathway
phas04931
Insulin resistance
phas04936
Alcoholic liver disease
Brite
KEGG Orthology (KO) [BR:
phas00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
123822289 (ACACB)
00640 Propanoate metabolism
123822289 (ACACB)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
123822289 (ACACB)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
123822289 (ACACB)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
123822289 (ACACB)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
123822289 (ACACB)
04922 Glucagon signaling pathway
123822289 (ACACB)
04920 Adipocytokine signaling pathway
123822289 (ACACB)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
123822289 (ACACB)
04931 Insulin resistance
123822289 (ACACB)
Enzymes [BR:
phas01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
123822289 (ACACB)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
123822289 (ACACB)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
123822289 (ACACB)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
ATPgrasp_Ter
Motif
Other DBs
NCBI-GeneID:
123822289
NCBI-ProteinID:
XP_045700233
LinkDB
All DBs
Position
Unknown
AA seq
2451 aa
AA seq
DB search
MTLLFFLSCLIVSYLTLSWLKIWGKMTDSTPATKNHSGANVLLNQEPLPASDSSEELQEN
GDSSSVPKTPDQAEPASPKGPKDARLRRTSRPPPYRSPQKSPLPSRDASPASGTDAGGPE
APDTNGVSSPSRPQARGRALSREDQKQAHIKRQLMTKFILGSFDDNSSDEDPGMSSFRES
SRRGSRASLGALSLEAARTAGRSESPVPTMRPSMSGLHLVRRGREHKKVDLHRDFTVASP
AEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKAN
AEYIKMADQYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLCKH
EIAFLGPPSEAMWALGDKIASTIVAQTLQIPTLPWSGSGLMVTLAEDDLRQGTRVCVPEN
TYNQGCVKDVDEGLEAAEKIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQVQSEIPGS
PVFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIATPAVFEFM
EQCAVRLAKTVGYVSAGTVEYLYSQDGSFYFLELNPRLQVEHPCTEMIADVNLPAAQLQI
AMGVPLHRLKDIRLLYGESPWGVTPISFDAPPNPPLPRGHVIAARITSENPDEGFKPSSG
TVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIR
GDFRTTVEYLVNLLETESFQNNDIDTGWLDHLIAEKVQAEKPDVMLGVVCGALNVADAMF
RTCMTDFLHSLERGQVLPAASLRNTVDVELIYGGFKYILKVARQSLTMFVLIMNNCHIEI
DAHRLNDGGLLLSYSGSSYTTYMKEEVNSYRITIGNKTCVFEKENDPTVLRAPSAGKLTQ
YTVEDGGHVEAGGSYAEMEVMKMIMALNVQESGRVKYIKRPGAVLEAGCVVARLELDDPS
KVHPAKPFTGELPPQPTLPIMGEKLNQVFHSVLENLINIMNGYCLPEPIFSIKLKEWVQK
LMMTLRHPSLPLLELQEIMTSVSGRIPAPVEKSVRRVMAQYASNITSVLCQFPSQQIATI
LDCHAATLQRKADREVFFMNTQSIVQLVQRYRSGTRGYMKAVVLDLLKRYLHVEHHFQQA
HYDKCVINLREQLKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSEELTSILN
ELTQLSKSEHCKVALRARQVLIASHLPSYELRHNQVESIFLSAIDRYGHQFCPENLKKLI
LSETTIFDVLPSFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCVVEFQFML
PSSHPNRMAVPISITNPDLLRHSTELFMDSGFSPLSQRMGAMVAFRRFEEFTRNFDDVIS
CFASVAEDTPLFSKAQTSVYCEEDCKNLREEPIHILNVAIQFADHPEDEELVPILRTFVQ
SKKNILVDYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQLELSRMRN
FDLAAVPCANHKMHLYLGAAKVKEGVEVTDHRFFIRAIIRHSDLITKEASFEYLQNEGER
LLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPYKIEESVRSMVMRYGSRLWKLRV
LQAEVKINIRQSTTGCTTPIRLFITNESGYYLDISLYKEVTDPQSGNIMFHSFGDKQGPQ
HGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDFPELFRQALFKMWGSPDKYPKDILTYTE
LVLDPQGQLVEMNRLPGGNEVGMVAFRMRFKTREYPEGRDVIVISNDITFRIGSFGMGED
LLYLRASERARAEGIPKIYLAANSGARIGLAEEIKHMFQVAWVDPEDPHKGFKYLYLTPQ
EYTRISSLNSVHCKHIEEEGESRYVITDVIGKEDGLGVENLRGSGTIAGESSLAYDEIVT
ISLVTCRALGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNSQLGGVQIMH
NNGISHVTVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPIDREVEFFPSRAPYDPRW
MLAGRPHPTLKGSWQSGFFDQGSFSEIMAPWAQTVVTGRARLGGIPVGVIAVETRTVEVA
VPADPANLDSEAKIIQQAGQVWFPDSAYKTAQVIKDFNRERLPLMIFANWRGFSGGMKDM
YDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVLDSTINPLCIEMYADKESRGG
VLEPEGTVEIKFRKKDLVKAMRRIDSTYKKLVEQLGKSELSDKERKDLEGQLKAREDLLL
PIYHQVAVQFADLQDTPGRMLEKGVISDVLEWKTSRTFLYWRLRRLLLEDQVKQEILQVS
SELSHVHIQSMLRRWFVETEGAVKAYLWDNNQMVVQWLEQHWQVGDGLRSAIHENIKYLK
RDSVLKTIRGLVQENPEVAVDCMMHMSQHISPAERARVAHLLSTMDSPAST
NT seq
7356 nt
NT seq
+upstream
nt +downstream
nt
atgaccctgcttttcttcctgtcttgtctgattgtctcctacctgaccttgtcctggtta
aaaatctgggggaaaatgaccgactccacgcccgccaccaagaaccactcgggggcaaac
gtcctcctgaaccaggagccccttccagcgtctgacagctcggaggagctgcaggaaaac
ggagacagcagctctgtgccaaagactcctgaccaggccgagccggcctccccgaaaggt
cccaaagatgcccgtctgcggagaacctcccggccgccgccgtatcggagtcctcagaaa
agcccccttccctcccgggatgcctccccagccagtgggacggacgctgggggcccggag
gccccagacaccaacggcgtgtcctcaccaagcaggccccaggcccgaggcagagccctg
tccagagaagaccagaaacaggcgcacatcaagcggcagctgatgaccaaattcatcctg
ggctccttcgatgacaactcctcggacgaggaccccggcatgagctccttccgggagtct
tcccgcaggggcagccgcgccagcctgggggccctgtccctggaggctgcccggactgca
ggccgctcggagtcccccgtccccacgatgaggcccagcatgtctgggctccacctggtg
aggaggggccgtgaacacaagaaggtggacctgcacagagacttcaccgtagcttccccg
gccgagttcgtcacacgctttgggggggatcgggtcatcgagaaggtgctcatcgccaac
aatggcatcgccgccgtgaagtgcatgcgctccatccgcaggtggtcctacgagatgttc
cgaaacgagcgggccatccggtttgtagtcatggtgactccggaggacctcaaggccaac
gcagagtacatcaagatggccgaccagtacgtcccagtgccggggggccccaacaacaac
aactacgccaacgtggagctcatcgtggacatcgccaagagaatccccgtgcaggcggtg
tgggctggctggggccacgcctccgaaaaccccaaacttccggagctcctgtgcaagcat
gagattgctttcttaggcccccccagcgaggccatgtgggccctgggagataagatcgcc
tccaccatcgtggcccagacactgcagatcccaacactgccctggagtggaagcggtctg
atggtgacactggcagaagatgacctgcggcaggggaccagagtctgtgtccccgagaac
acttacaaccagggttgtgtgaaggacgtggacgaggggttggaggcagcagagaaaatc
ggttttccgttgatgatcaaagcttcggaaggcggcggagggaaaggaatccggaaggca
gagagcgcggaggacttcccgatcctgttcagacaagtacagagcgagatcccgggctcc
cccgtcttcctcatgaagctggcccagcacgcccgtcacctggaggtccagatcctcgcc
gaccagtacggcaacgccgtgtccctgtttgggcgagactgctccatccagcggcggcat
cagaagatcatcgaggaggcccctgccaccatcgccaccccggccgtgttcgagttcatg
gagcagtgtgccgtccgcctggccaagacggtgggctacgtgagcgcggggacggtggaa
tacctgtacagccaggacggcagcttctacttcttggagctgaacccccgcctgcaggtg
gagcacccctgcacggagatgatcgccgacgtgaacctgccggccgcccagctgcagatc
gccatgggcgtgccgctgcaccggctgaaagacatccgccttctgtacggagagtctccg
tggggggtgacgcccatttcttttgacgcccctcccaacccgcccctgccccgaggccac
gttattgcagccagaatcaccagcgaaaatcccgacgaggggtttaagccgagctccggg
acagtccaggaactgaatttccgcagcagcaagaacgtgtggggttatttcagcgtggcc
gccaccggcggcttacacgagtttgccgattcccagttcgggcactgcttctcctgggga
gagaaccgggaagaggccatttcgaacatggtggtggctttgaaggaactgtccatccgg
ggcgacttcaggaccaccgtggagtatctcgtcaacctcctggagaccgagagtttccag
aacaacgacatcgacactgggtggttggaccacctcatcgccgagaaagtgcaggcagaa
aagccagatgtcatgctcggggtggtgtgcggggccttgaacgtggccgatgcgatgttc
agaacctgcatgacggatttcttgcactcgctggaaaggggccaggtgctgcccgcagca
tccctgcggaacacggtggacgtggaactgatctacggaggctttaagtacatcctcaag
gtggcccggcagtcgctgaccatgttcgtcctcatcatgaacaactgtcacattgagatc
gacgcccaccggctgaacgacggcgggctcctgctgtcctacagcggcagcagctacacg
acctacatgaaggaggaggtcaacagttaccggattaccatcggcaacaagacatgtgtg
tttgagaaggagaacgaccccacggtgctgagagccccctcggccgggaagctgacgcag
tacacggtggaggacgggggccacgtggaggcggggggcagctacgccgagatggaggtg
atgaagatgatcatggccctgaacgtgcaggagagtggccgggtgaagtacatcaagcgc
ccgggcgccgtgctggaggcgggctgcgtggtggccaggctggagctcgacgacccctct
aaggtgcacccggccaagccgttcacaggagagctccctccccagccaactctgcccatc
atgggggagaaactgaaccaggtcttccacagcgtcctggaaaacctgatcaacatcatg
aatggctactgcctgcccgagcccatctttagcataaagctgaaggagtgggtgcagaag
ctcatgatgaccctgcgccacccgtcgctgcctctgctggagctgcaggagatcatgacc
agcgtgtcgggccgcatccctgcccccgtggagaagtcggtccgcagggtgatggcccag
tacgccagcaacatcacctcggtgctctgccagttccccagccagcagatagccaccatc
ctggactgccacgcggccacgctgcagcggaaggccgaccgggaagtcttcttcatgaac
acgcagagcatcgtgcagctggtgcagagataccgcagcgggacccgcggctacatgaag
gcggtggtgttggatctgctgaaaagatacctgcacgtggagcaccatttccaacaagcc
cactacgacaagtgtgtgatcaacctcagggagcagctgaagccagacatgtcccaggtg
ctggactgcatcttctcccacgcgcaggtggccaagaagaaccagctggtgatcatgttg
attgatgaactctgtggcccagacccttccctgtcggaggagctgacctccatcctcaat
gagctcacccagctgagcaagagcgagcactgcaaagtagccctccgagccagacaggtc
ctgatcgcctcccacctcccctcctatgagctgaggcacaaccaggtggagtccattttc
ctgtctgccattgacaggtacggccaccagttctgcccggaaaacctcaagaaattgata
ctctcagaaacgaccatattcgacgtgctgccttctttcttctatcacgctaacaaggtc
gtgtgcatggcgtccttggaggtttatgtgcggaggggctacatcgcctacgagctgaac
agcctgcagcaccggcagctcccggacggcacctgcgtggtggaattccagttcatgctg
ccctcctcccacccaaaccggatggccgtgcccatcagcatcaccaaccccgacctgctg
agacacagcaccgagctcttcatggacagcggcttctccccgctgtcccagcggatgggc
gccatggtcgctttcaggagattcgaggagttcaccaggaacttcgatgatgtcatctcc
tgcttcgccagtgtggccgaggacacgccactcttcagcaaggcccagacgtccgtgtac
tgtgaggaggactgcaagaacctccgggaggagcccatccacatcctgaacgtggccatc
cagttcgccgaccacccggaggacgaggagctggtgccgattttgcggaccttcgtgcag
tccaagaagaacatcctcgtggattacgggctccggaggatcacgttcctgattgcccag
gagaaagaatttcccaagtttttcacgttcagagcaagagatgagttcgcagaagaccgc
atttaccgtcacctggagcccgccctggccttccagctggagctcagccggatgcgcaat
tttgacctggccgccgtgccctgcgccaaccacaagatgcacctttacctgggcgctgcc
aaggtgaaggagggcgtggaagtgacagaccaccgcttcttcatccgcgccatcatccgg
cactcggacctgatcacaaaggaagcctccttcgagtacctgcagaacgagggcgagcgg
ctgctgctggaggccatggacgagctggaggtggcgttcaacaacaccagcgtgcgcacc
gactgcaaccacatcttcctcaacttcgtgcccaccgtcatcatggacccctacaagatc
gaggagtcggtgcgttccatggtcatgcgctacggcagcaggttgtggaagctccgcgtg
ctgcaggccgaggtcaagatcaacatccgccagtccaccactggctgcaccactcccatc
cgcctgttcatcaccaacgagtcaggctactacctggacatcagcctctacaaagaagtc
accgacccccaatcgggaaatatcatgttccactcctttggcgacaaacaagggccccag
cacggcatgctgatcaacactccctacgtcaccaaggacctgctccaggccaagcggttc
caggcccagtccctggggaccacctacgtgtacgacttcccagagctgttcaggcaggct
ctctttaaaatgtggggctccccagacaagtaccccaaagacatcctgacgtacacggag
ctcgtgctggacccccagggccagctggtggagatgaaccgactccccggcggaaacgag
gtgggcatggtggccttcaggatgcggttcaagacccgggagtatccagaagggcgggac
gtgatcgtcatcagcaacgacatcaccttccgcatcggatccttcggcatgggggaggac
ctgctgtacctgcgggcgtccgagagggcccgggccgagggcatccccaaaatctacctc
gcggccaacagcggggcccggatcggcctcgcggaggagattaaacacatgttccaggtg
gcttgggtggacccggaagacccccacaaaggatttaaatacctgtacttgacccctcaa
gagtacaccagaatcagctccctgaactccgtgcactgcaaacacatcgaggaagaagga
gaatccaggtacgtgatcacggacgtcatcgggaaggaggacggcctgggcgtggagaac
ctgcggggctccggcacgatcgccggcgagtcctccctggcttacgacgagatcgtcacc
attagcctggtgacctgccgagccctcgggatcggcgcctacttggtgaggctgggccag
cgcgtgatccaggtggagaactcccacatcattctcacgggagccagcgcgctcaacaag
gtcctgggcagagaggtttacacgtccaacagccagctgggcggcgtgcagatcatgcac
aacaacggcatctcccacgtcaccgtgccggacgacttcgagggcgtgtacaccatcctg
gagtggctgtcctacatgccgaaggataatcacagcccggtccctatcatcactcccacg
gaccccatcgacagagaagttgagtttttcccctcgagagccccgtacgacccccggtgg
atgctggcgggaaggcctcacccaactctgaagggatcctggcagagtggattcttcgac
cagggcagcttcagtgaaatcatggcgccctgggcccagaccgtggtgacgggacgtgcc
aggctggggggcatccctgtcggagtgatcgccgtggagactcggaccgtggaggtggcg
gtgcccgcagaccccgccaacctggattccgaagcgaagatcatccagcaggcaggccag
gtgtggttcccggactcggcctacaagacagcccaggtcatcaaggacttcaaccgggag
aggctgcccctgatgatctttgccaactggaggggcttctctggtggcatgaaagacatg
tacgatcaggtgttgaagttcggagcctacattgtggacggcctccggcagtacaagcag
cccatcctcatctacatcccgccctacgcggagctccggggaggctcctgggtggtgctg
gactccaccatcaaccctctgtgcatagagatgtacgcggacaaggagagcagggggggt
gtcctggagccggagggaacagtggagattaagttccgaaagaaagatctggtaaaggcc
atgaggaggattgacagcacttacaagaagctcgtggagcagttaggaaagtctgagctc
tcggacaaagaacgcaaggacctggaaggccagctgaaggcccgggaggacctgctgctg
cccatctaccaccaggtggcggtgcagttcgccgacctccaggacacgccgggcaggatg
ctggagaagggcgtcatctctgatgtcctggagtggaagacctcacgcaccttcctgtac
tggcgtctgcgccgcctcctgctggaggaccaggtcaagcaggagatcctgcaggtcagc
agcgagctgagccacgtgcacatccagtccatgctgcgccgctggttcgtggagacggag
ggggctgtcaaggcctacctgtgggacaacaaccagatggtggtacagtggctggagcag
cactggcaggtgggggacggcctgcgctccgccatacacgagaacatcaagtacctgaag
cgggactcggtgctcaagaccatccggggcctggtccaggaaaaccccgaggtggccgtg
gactgcatgatgcacatgagccagcacatcagcccagccgagcgggcccgcgtcgctcac
ctgctgtccaccatggacagccccgcctccacctga
DBGET
integrated database retrieval system
