Phyllostomus hastatus (greater spear-nosed bat): 123833093
Help
Entry
123833093 CDS
T07912
Symbol
ADCY8
Name
(RefSeq) adenylate cyclase type 8
KO
K08048
adenylate cyclase 8 [EC:
4.6.1.1
]
Organism
phas
Phyllostomus hastatus (greater spear-nosed bat)
Pathway
phas00230
Purine metabolism
phas01100
Metabolic pathways
phas01522
Endocrine resistance
phas04015
Rap1 signaling pathway
phas04020
Calcium signaling pathway
phas04022
cGMP-PKG signaling pathway
phas04024
cAMP signaling pathway
phas04062
Chemokine signaling pathway
phas04072
Phospholipase D signaling pathway
phas04114
Oocyte meiosis
phas04211
Longevity regulating pathway
phas04213
Longevity regulating pathway - multiple species
phas04261
Adrenergic signaling in cardiomyocytes
phas04270
Vascular smooth muscle contraction
phas04371
Apelin signaling pathway
phas04540
Gap junction
phas04611
Platelet activation
phas04713
Circadian entrainment
phas04714
Thermogenesis
phas04720
Long-term potentiation
phas04723
Retrograde endocannabinoid signaling
phas04724
Glutamatergic synapse
phas04725
Cholinergic synapse
phas04727
GABAergic synapse
phas04742
Taste transduction
phas04750
Inflammatory mediator regulation of TRP channels
phas04911
Insulin secretion
phas04912
GnRH signaling pathway
phas04913
Ovarian steroidogenesis
phas04914
Progesterone-mediated oocyte maturation
phas04915
Estrogen signaling pathway
phas04916
Melanogenesis
phas04918
Thyroid hormone synthesis
phas04921
Oxytocin signaling pathway
phas04923
Regulation of lipolysis in adipocytes
phas04925
Aldosterone synthesis and secretion
phas04926
Relaxin signaling pathway
phas04927
Cortisol synthesis and secretion
phas04928
Parathyroid hormone synthesis, secretion and action
phas04934
Cushing syndrome
phas04935
Growth hormone synthesis, secretion and action
phas04970
Salivary secretion
phas04971
Gastric acid secretion
phas04972
Pancreatic secretion
phas04976
Bile secretion
phas05032
Morphine addiction
phas05163
Human cytomegalovirus infection
phas05166
Human T-cell leukemia virus 1 infection
phas05200
Pathways in cancer
phas05207
Chemical carcinogenesis - receptor activation
phas05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
phas00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
123833093 (ADCY8)
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
123833093 (ADCY8)
04371 Apelin signaling pathway
123833093 (ADCY8)
04020 Calcium signaling pathway
123833093 (ADCY8)
04072 Phospholipase D signaling pathway
123833093 (ADCY8)
04024 cAMP signaling pathway
123833093 (ADCY8)
04022 cGMP-PKG signaling pathway
123833093 (ADCY8)
09140 Cellular Processes
09143 Cell growth and death
04114 Oocyte meiosis
123833093 (ADCY8)
09144 Cellular community - eukaryotes
04540 Gap junction
123833093 (ADCY8)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
123833093 (ADCY8)
04062 Chemokine signaling pathway
123833093 (ADCY8)
09152 Endocrine system
04911 Insulin secretion
123833093 (ADCY8)
04923 Regulation of lipolysis in adipocytes
123833093 (ADCY8)
04912 GnRH signaling pathway
123833093 (ADCY8)
04913 Ovarian steroidogenesis
123833093 (ADCY8)
04915 Estrogen signaling pathway
123833093 (ADCY8)
04914 Progesterone-mediated oocyte maturation
123833093 (ADCY8)
04921 Oxytocin signaling pathway
123833093 (ADCY8)
04926 Relaxin signaling pathway
123833093 (ADCY8)
04935 Growth hormone synthesis, secretion and action
123833093 (ADCY8)
04918 Thyroid hormone synthesis
123833093 (ADCY8)
04928 Parathyroid hormone synthesis, secretion and action
123833093 (ADCY8)
04916 Melanogenesis
123833093 (ADCY8)
04925 Aldosterone synthesis and secretion
123833093 (ADCY8)
04927 Cortisol synthesis and secretion
123833093 (ADCY8)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
123833093 (ADCY8)
04270 Vascular smooth muscle contraction
123833093 (ADCY8)
09154 Digestive system
04970 Salivary secretion
123833093 (ADCY8)
04971 Gastric acid secretion
123833093 (ADCY8)
04972 Pancreatic secretion
123833093 (ADCY8)
04976 Bile secretion
123833093 (ADCY8)
09156 Nervous system
04724 Glutamatergic synapse
123833093 (ADCY8)
04727 GABAergic synapse
123833093 (ADCY8)
04725 Cholinergic synapse
123833093 (ADCY8)
04720 Long-term potentiation
123833093 (ADCY8)
04723 Retrograde endocannabinoid signaling
123833093 (ADCY8)
09157 Sensory system
04742 Taste transduction
123833093 (ADCY8)
04750 Inflammatory mediator regulation of TRP channels
123833093 (ADCY8)
09149 Aging
04211 Longevity regulating pathway
123833093 (ADCY8)
04213 Longevity regulating pathway - multiple species
123833093 (ADCY8)
09159 Environmental adaptation
04713 Circadian entrainment
123833093 (ADCY8)
04714 Thermogenesis
123833093 (ADCY8)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123833093 (ADCY8)
05207 Chemical carcinogenesis - receptor activation
123833093 (ADCY8)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
123833093 (ADCY8)
05163 Human cytomegalovirus infection
123833093 (ADCY8)
09165 Substance dependence
05032 Morphine addiction
123833093 (ADCY8)
09166 Cardiovascular disease
05414 Dilated cardiomyopathy
123833093 (ADCY8)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
123833093 (ADCY8)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
123833093 (ADCY8)
Enzymes [BR:
phas01000
]
4. Lyases
4.6 Phosphorus-oxygen lyases
4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date)
4.6.1.1 adenylate cyclase
123833093 (ADCY8)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Guanylate_cyc
AC_N
Adcy_cons_dom
TBK1_ULD
Motif
Other DBs
NCBI-GeneID:
123833093
NCBI-ProteinID:
XP_045717105
LinkDB
All DBs
Position
Unknown
AA seq
1253 aa
AA seq
DB search
MELSDVRCLSGSEELYTIHPTPPAGDGGSGSRPQRLLWQTAVRHITEQRFIHGHRGSGGG
SGGSGGSGKGSDPAGGGPNHHASQLSGDSALPLYSLGPGERARSSGGTKVFPERSGSGSA
SGSGGGGDLGFLHLDCAPSNSDFFLSGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQR
RKSEVVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTS
HTYLQYSGVVTWVAMTTQVLAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAIVAGLG
TSLLQVILQVVIPRLAVISINQVVAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVE
ARLRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFA
DVKGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDH
AHCCVEMGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIAN
KLESGGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEESLLSLP
EDIVKESVSCSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQAL
HVQSGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVC
AFIVLLFITAIQSLLPSSRVMPMAIQFSILIMLHSALVLITTAEDYKCLPLILRKTCCWI
NETYLARNVIIFASILINFLGAILNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVF
TGVLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYAGLFLRYDKLNHSGEDFLGTK
EASLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSH
VARHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADF
DELLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEIN
KHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYL
ILKDQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLG
LVQSLNRQRQKQLLNENNNTGIIKGHYNRRTLLTPSGSEPGTQAEGADKSDLP
NT seq
3762 nt
NT seq
+upstream
nt +downstream
nt
atggagctctcggatgtgcgctgccttagcggcagcgaggaactctacaccatccacccg
acgcccccggccggcgacggcgggagcggctctcggccacagcggctgctgtggcagacg
gcggtgcggcacattactgagcagcgcttcattcatgggcaccggggcagcggcggcggc
agcggagggagtggaggctccggcaaaggctcggaccctgcaggcggcggccccaaccac
cacgcttcgcagctgtccggcgactcggcgctgcctctctactcactggggccgggggag
agagcgcgcagctcggggggcaccaaagtcttcccggaacgcagcgggagcggcagcgcc
agcggcagcgggggagggggcgacctgggcttcctgcacctcgactgcgccccaagcaac
tcggatttcttcctcagtgggggctatagctaccgaggggtcatcttccccaccctgcgc
aactcgttcaagtcccgggatctggagcgcctctaccagcgctatttcctgggccagcgg
cgcaaatccgaggtggtgatgaacgtgctggatgtgctgaccaaactcaccctgctggtt
ctccacttgagcctggcctcggcccccatggacccgctcaagggtattctgctgggcttc
ttcaccggcatcgaggtggtgatctgcgccctggtggtggtcaggaaggacaccacctct
cacacgtacctgcagtacagcggcgtggtcacctgggtggccatgaccacccaggtcttg
gcagcaggccttggctatgggctcctgggagatggcatcggctacgtgctcttcacactt
ttcgccacctacagcatgctgccgctgccgctcacctgggccatcgtggccggcttgggc
acctcgctgctgcaggtgatcctccaagtggtgatcccccgtctggcggtcatttccatc
aaccaggttgtggcccaggctgtgttattcatgtgcatgaacacagctggcatcttcatc
agttacctgtcagaccgggcccagcgccaggccttcctggagacgcggaggtgcgtggag
gccaggctgcggctggagacggaaaaccagagacaggagcggctcgtgctgtccgtgctc
ccccgatttgtcgtcctggagatgatcaacgacatgaccaacgtggaagatgagcacctg
cagcaccagttccaccggatctacatccaccgctacgagaacgtcagtattctttttgca
gatgttaaaggattcaccaacctctccaccaccttgtctgctcaggagctggtcaggatg
ctcaacgagctctttgccagatttgatcgactggcccatgagcaccactgtctccgcatc
aaaatcctaggggactgctactactgtgtttctggacttccggagccccgccaggaccac
gcccactgctgtgtggaaatgggcctcagcatgatcaaaaccatcaggtatgtgcggtca
aggacgaagcatgatgtggacatgcggatcgggatccactcaggctccgtgctgtgcggc
gtgctgggcctgcgcaagtggcagtttgacgtctggtcctgggacgtggacattgcgaac
aagctggagtcgggagggattcccgggaggattcacatctccaaggccacgctcgactgc
ctcaacggtgactacaacgtggaggagggccacgggaaagagaggaacgaattcttgagg
aagcataacatagagacctatttaatcaagcagcccgaggagagcctgctgtccctgcct
gaagacatcgtcaaggagtcggtgagctgctcggacaggagaaacagcggggcgacgttc
accgaagggtcctggagccccgaactgcccttcgacaacatagtggggaaacagaacact
ctggctgccctaacaagaaattcaataaatctacttccaaaccatcttgcacaagctttg
catgtccagtcggggcctgaggaaattaacaagcgcatagaacataccatcgacttgcgg
agtggcgataaattgcgaagagagcatatcaagccattctcactgatgtttaaagactcc
agcctggagcacaagtattctcaaatgagggacgaagtgttcaagtcaaacttggtctgt
gcgtttatcgttcttctgtttatcacggccatacaaagtttgcttccttcttcaagggtg
atgcccatggccatccagttttccatcctgatcatgctgcactcggcactggtgctcatc
accacggcggaggattacaagtgtttgcccctcatcctccggaaaacttgctgttggatc
aatgaaacctatctggcccggaacgtcatcatctttgcgtccatcctgatcaatttccta
ggcgccatcctaaatatcctgtggtgcgattttgacaagtcgatacccttgaagaacctg
actttcaattcctcagctgtgtttacagatatctgctcctacccagagtactttgtcttc
acgggcgtgctggccatggtgacctgtgcggtattcctccgacttaactctgtcctgaag
ctggccgtgctgctgatcatgatcgccatctacgccctgctgaccgagaccatctacgcg
ggcctcttcctgcgctatgacaagctgaaccacagtggagaagacttcctggggaccaag
gaggcgtcgctgctgctgatggccatgttcctccttgctgtgttctaccatggacagcag
ctggagtacacagcccgcctggacttcctttggcgagtccaggccaaagaggaaatcaac
gagatgaaggagctgagggagcacaacgagaacatgctccggaacatcctgcccagccac
gtggcccgccatttcctggagaaggaccgcgacaacgaggagctgtattcgcagtcctac
gacgccgtcggcgtgatgttcgcctccatcccggggtttgcggacttctactctcagact
gagatgaacaaccagggagtggagtgcctgcgcctgctgaacgagatcattgctgacttc
gatgagctgctcggtgaggaccggtttcaagacatcgaaaagatcaagaccattggcagc
acctacatggcggtctcaggtctgtcacctgaaaaacagcaatgcgaagacaagtgggga
cacctgtgcgcgctggccgacttctccctcgccctgactgagagcatacaggagatcaac
aagcactccttcaacaacttcgagctccggatcggcatcagccacggttccgtggtggcc
ggcgtcatcggcgctaagaagccgcagtacgacatctggggcaaaaccgtgaacctggcc
agtcgcatggacagcaccggcgtcagcggcaggatccaagtcccagaggagacctatctc
atcctgaaggaccagggcttcgcctttgactaccgaggggagatctacgtgaagggcatc
agcgaacaggaagggaaaatcaaaacgtactttctcctgggcagggtccagcccaacccg
ttcatcttgcccccgaggaggctgccggggcagtactccctggccgccgtcgtgctgggc
ctcgtgcagtccctcaacaggcaaaggcagaagcagctcctcaacgagaacaacaacacg
ggcatcatcaagggccattacaaccggcggactttgctgacacccagcgggtcggagccc
ggaacccaagccgagggtgccgacaagtccgatttgccataa
DBGET
integrated database retrieval system
