Pseudomonas kielensis: Q1W70_20250
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Entry
Q1W70_20250 CDS
T09328
Symbol
folC
Name
(GenBank) bifunctional tetrahydrofolate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
pkj
Pseudomonas kielensis
Pathway
pkj00790
Folate biosynthesis
pkj01100
Metabolic pathways
pkj01240
Biosynthesis of cofactors
Module
pkj_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
pkj00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
Q1W70_20250 (folC)
Enzymes [BR:
pkj01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
Q1W70_20250 (folC)
6.3.2.17 tetrahydrofolate synthase
Q1W70_20250 (folC)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
WKL51779
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Position
4329732..4331039
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AA seq
435 aa
AA seq
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MTQRTLGEWLAYLEQLHPSAIDMGLARSQEVASRMGLGKPAPRVITVTGTNGKGSTCAFV
ASLLRAQGLKVGVYNSPHLLHYNERVQVNGVLATDEQLCEAFAAVEAGRGEISLTYFEMG
TLAAFWLFQRAGLDAVVLEVGLGGRLDTVNLVDADIALVTSIGVDHADYLGNTRESVAFE
KAGIFRQGAPALCGDLNPPQPLLDKARELACPFFLRGRDFDLGVTDQHWQWRGVDGQGRA
LELRDLPLLDLPMENAALALQAYALLGLPWVPEQIAAALQATRVVGRLDRRQFNWHGKRL
NLMLDVGHNPHAAEYLAQRLARRPVAGRRLAVFGLLADKDLDGVVGELSASVQHWAVAPL
DSARARPVADLQAALQNLGASVTSYASVAEALEGQSAQATADDEILLFGSFYCVAEALEW
LARHSTEEAADGFAG
NT seq
1308 nt
NT seq
+upstream
nt +downstream
nt
atgacccaacgtacccttggcgaatggctcgcctaccttgagcagttgcatccctccgcc
atcgacatggggcttgcgcgctcgcaagaggtagcgtcccggatggggctgggcaagccg
gcgcctcgggtgatcacggtcaccggcaccaacggcaagggttctacctgtgcgttcgtg
gcgtctttgctgcgcgcacagggcctgaaggtcggtgtctacaattctccgcacctgctg
cattacaacgagcgggtgcaggtcaatggcgtgctggccactgacgaacagctgtgcgag
gccttcgctgcggtggaggcggggcgtggcgaaatctccctgacttacttcgaaatgggc
accctggcagcgttctggctgttccagcgcgcaggcctggatgcggtggtcctggaagtt
ggccttggcgggcgcctggacacggtcaacctggtggatgcggatatcgcgctggtcacc
agtatcggtgtcgatcatgccgactacctgggcaatacccgcgaatcggtggcctttgag
aaggccgggattttccgtcagggcgccccggcgctgtgcggcgacctcaatccgccgcaa
ccgctgctggataaggcgcgcgaactggcctgtccctttttcctgcgggggcgcgatttt
gacctgggcgtgaccgaccagcactggcaatggcgcggtgtcgacggccaggggcgtgcc
cttgagctgcgggatctgccattgctcgacctgccgatggaaaacgccgcactggcgctg
caggcctacgccttgctgggcttgccctgggtgcctgagcagatcgccgcggcattgcag
gcgacccgcgtggtcgggcgcctggatcggcgtcagttcaactggcatggcaagcgcctg
aacctgatgctggacgtcgggcacaacccgcacgcggccgagtacctggcgcagcgcctg
gcgcggcgtccggtggcggggcgacgcctggcggtcttcggtttgctggccgacaaggat
cttgatggagttgtcggtgaattgagtgctagtgtccagcactgggctgtcgccccgctg
gattctgcgcgtgcgcgcccggttgcggatttacaggctgcattgcagaaccttggcgcg
tccgtgacctcctatgcaagcgtggccgaggccctggaagggcagagcgcgcaggcaacg
gcagacgacgagatcctgctgttcggatcattttattgtgtcgccgaggcccttgaatgg
ctggcccggcactccacggaggaagctgcagatggctttgctggataa
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