Pipistrellus kuhlii (Kuhl's pipistrelle): 118719823
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Entry
118719823 CDS
T07682
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
pkl
Pipistrellus kuhlii (Kuhl's pipistrelle)
Pathway
pkl00010
Glycolysis / Gluconeogenesis
pkl00020
Citrate cycle (TCA cycle)
pkl00620
Pyruvate metabolism
pkl00785
Lipoic acid metabolism
pkl01100
Metabolic pathways
pkl01200
Carbon metabolism
pkl01210
2-Oxocarboxylic acid metabolism
pkl04066
HIF-1 signaling pathway
pkl04922
Glucagon signaling pathway
pkl05230
Central carbon metabolism in cancer
pkl05415
Diabetic cardiomyopathy
Module
pkl_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
pkl00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
118719823 (PDHA1)
00020 Citrate cycle (TCA cycle)
118719823 (PDHA1)
00620 Pyruvate metabolism
118719823 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
118719823 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
118719823 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
118719823 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
118719823 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
118719823 (PDHA1)
Enzymes [BR:
pkl01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
118719823 (PDHA1)
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Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
118719823
NCBI-ProteinID:
XP_036295516
LinkDB
All DBs
Position
Unknown
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGAAQKPASRVLVGSRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLRYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGMEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGMRVDGMDVLCVREATKFAAAHCRAGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSNEPPFEVRGANQWIKFKSIS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgccgtctcccgcgtgctgtcgggcgctgcccagaagccggca
agcagagtgctggtgggatcccggaattttgcaaatgatgctacatttgaaattaagaag
tgtgaccttcaccggctggaagagggccctcctgtcaccactgtgctcacccgggaggat
gggctccgatactacaggatgatgcagactgttcgccggatggagctaaaggcagatcag
ctgtataagcagaaaattatccgtggtttctgtcacttgtgtgatggtcaggaagcttgt
tgcgtgggcatggaagctggcataaatcccacagaccatctgatcacagcctatcgggct
catggctttacctttactcgtgggctttctgttcgagaaattctcgcagagcttacagga
cgcagaggaggctgtgctaaaggaaaaggaggatcaatgcatatgtacgccaagaatttc
tacgggggcaatggcatcgttggagctcaggtgcccctgggagctgggattgctctggcc
tgcaagtataatggaaaagatgaggtctgtttgactttgtatggcgatggcgctgctaac
cagggtcagatatttgaagcttacaatatggcagctttgtggaaattgccttgtattttc
atctgtgaaaataaccgctacgggatgggaacgtctgttgagagagcagcagccagcacg
gattactacaagaggggcgacttcattcctgggatgagggtggatggaatggatgtcctg
tgtgtccgggaggcaacaaagtttgcagctgcccattgtagggctggaaaggggcctatt
ctaatggagctgcagacttaccgttaccatggacacagcatgagtgatcctggagtcagt
taccgtacccgagaggaaattcaggaagtgagaagtaagagtgaccccatcatgcttctc
aaggatagaatggtgaacagcaatcttgccagtgttgaagaattaaaggaaattgatgtc
gaagtgaggaaagaaattgaggatgctgcccaatttgctacagctgatcctgaaccacct
ttggaagaactaggctatcacatctactccaacgagccaccttttgaagttcggggtgcc
aatcagtggattaagtttaagtccatcagttaa
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