Peromyscus leucopus (white-footed mouse): 114702463
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Entry
114702463 CDS
T07241
Symbol
Plce1
Name
(RefSeq) LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
pleu
Peromyscus leucopus (white-footed mouse)
Pathway
pleu00562
Inositol phosphate metabolism
pleu01100
Metabolic pathways
pleu04014
Ras signaling pathway
pleu04015
Rap1 signaling pathway
pleu04020
Calcium signaling pathway
pleu04024
cAMP signaling pathway
pleu04070
Phosphatidylinositol signaling system
pleu04919
Thyroid hormone signaling pathway
pleu04933
AGE-RAGE signaling pathway in diabetic complications
pleu05205
Proteoglycans in cancer
Module
pleu_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
pleu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
114702463 (Plce1)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
114702463 (Plce1)
04015 Rap1 signaling pathway
114702463 (Plce1)
04020 Calcium signaling pathway
114702463 (Plce1)
04070 Phosphatidylinositol signaling system
114702463 (Plce1)
04024 cAMP signaling pathway
114702463 (Plce1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
114702463 (Plce1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
114702463 (Plce1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
114702463 (Plce1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pleu04131
]
114702463 (Plce1)
Enzymes [BR:
pleu01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
114702463 (Plce1)
Membrane trafficking [BR:
pleu04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
114702463 (Plce1)
Endocytosis
Macropinocytosis
Phospholipase C
114702463 (Plce1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
C2
EF-hand_like
Motif
Other DBs
NCBI-GeneID:
114702463
NCBI-ProteinID:
XP_028738744
LinkDB
All DBs
Position
1:45686001..45976203
Genome browser
AA seq
2283 aa
AA seq
DB search
MTSEEMAASVLIPVTQRKVASAQSAVAEDKSEKVSDAGVPKACAGMQSGQIPHTISRWSK
PEAEPSRSDLFKVLSIASGEMMSDENHNEKCWEQNLPDSVRNHAMNCNSSLQSHQGGLPQ
SQLWETCDSVTEEDLRLQTGISSPLERKAFPGLQLEMDDPPMDVSPLGNEPGIMENSGPH
PDSNMAEFHFHYETDRTMSDAFHTLSEKLILDDCANCVTLPGGQLKKNYVVYACKLMEPT
INCGNKNGQLQCDHCSSLHDKYLCLESSCRQPHICSGGGLCREGSTHSPPAKTFLGPLEE
FSDSCDDGDDFFRSKKERSTLLVRRFCKNDREVKRSVYTGTRAIVRTLPSGHIGPAAWNH
VNQKRARLLGPFGDLMEPLSAMDIRPRGSQWLSEAQWCLIYSAVRRGDETEDTVGSLLHC
SRQLPTSETACGRIRDAPCLKQCVRDTECEYRATLQRTSIAQYITGSLLEATTSLGARSG
LLSTFGGSTGRIMLKERQPGTSMANSNTVPSSSAGISKELIDLQPLIQFPEEVASILTEQ
EQNIYRRVLPIDYLCFLTRDLSSPECQSSLPRLKASISASILTSQNGEHNALEDLVMRFN
EVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMWQF
MDQSDIETMRSLKDAMAQHESSLEYKKVVTRALHIPGCKVVPFCGVFLKELCEVLDGASG
LLKLCPRYGSQEEALEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQIIRSCSRSLE
MEEEDSPSEGAGSRKNSLKDKARWQFIIGDLLDSENDIFEKSKECDPHGSEESQKAFDHG
TELIPWYVLSIQADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWMKPPTASPT
GARPKLGILSNTSEPGKFPSLGSAGLSGLAEGILDLFSVKAVYMGHPGIDIHTVCVQNKL
SSLLLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTTAVRKIRKFPDQRQQW
LRKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSARNPSPGMSAKNAEKPNMQRNNTLGIS
TTKKKKKMLMRGESGEATDDEMATRKAKMYRECRSRSGSDPQDVNEQEESEANAIASPPN
SLHSRRAHSLTTAGSPNLATGMSSPISAWSSSSWHGRIKGGMKGFQSFMVSDSNMSFIEF
VELFKSFSIRSRKDLKDIFDIYSVPCNRSASESAPLYTNLTIEENTSDLQPDLDLLTRNV
SDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGIESTSLGIFGVGILQLNDFLVNCQG
EHCTYDEILSIIQKFEPNISMCHQGLMSFEGFARFLMDKDNFASKNDESRENKKELQFPL
SYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSIELDCWDGDDGMPIIYHGHTLTT
KIPFQVVEAIDRSAFITSDLPIIISIENHCSLPQQRKMADIFKSVFGEKLVAKFLFETDF
SDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLASMQAQAFTGGNANPPPASN
EEEEDEEDEYDYDYESLSDDNILEDKPENKSCVDKLQFEYNEEIPKRIKKADNSSCNKGK
VYDMELGEEFYLPQNKKESRQIAPELSDLIIYCQAVKFPGLSTLNSSGSSRGKERKSRKS
IFGNNPGRMSPGETASFNRTSGKSSYEGIRQTWEESSSPLSPSTSLSAIIRTPKCYHISS
LNENAAKRLCRRYSQKLIQHTACQLLRTYPAATRIDSSNPNPLMFWLHGIQLVALNYQTD
DLPLHLNAAMFEANGGCGYVLKPPVLWDKSCPMYQKFSPLERDLDNMDPAIYSLTIISGQ
NVCPSNSTGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMWNEQFLFRVHFEDLVFLRFA
VVENNSSAITAQRIIPLKALKRGYRHLQLRNLHNEILEISSLFINSRRMEDNPSGSTMPA
SSMFNTEERKCSQTHRVTVHGVPGPEPFAVFTISGGTKAKQLLQQILVMDKDTKHTATDY
FLMEEKYFISKEKSECKKQPFQRTVGPEEDIVQILNSWFPEEGYVGRIVLKPQQETVEEK
SIVQDDKEVILSSEEESFFVQVHDVSPEQPRTVIKAPRVSTAQDVIQQTLCKAKYSYSIL
NNPNPGDYVLLEEVMKDAPNKKSSTPKSSQRILLDQECVFQAQSKWKGAGKFILKLKEQV
QASREDKRRGISFASELKKLTKSTKQPRGLTSPPQLVASESVQIKEEKPVGALSXSDTVG
YQQ
NT seq
6852 nt
NT seq
+upstream
nt +downstream
nt
atgacttccgaagaaatggcagcttccgtcctcatccctgtgactcagaggaaagtggct
tccgcccagtcagcagtggcagaggacaagagtgaaaaggtctcagatgctggtgtccca
aaggcatgtgccggcatgcagagtggccagatccctcataccatctcacggtggagcaag
cctgaggccgagccttctagaagtgatttgttcaaggtcctctcaatagcaagtggggag
atgatgagtgacgagaaccacaatgaaaagtgctgggaacaaaacctcccggattctgtg
aggaaccacgccatgaactgcaacagctcattgcaaagccaccagggtggccttcctcag
agccagctttgggaaacctgtgactctgtcaccgaagaggacctgcgtttgcaaactgga
atttcttctccactggaaaggaaggcattccctggacttcaactggaaatggatgaccct
cctatggatgtgagccctttgggaaacgagcctggaatcatggagaacagcggacctcac
cctgacagcaacatggcagaatttcatttccactatgaaactgacagaacaatgtcggac
gcttttcataccctgtcggaaaaattaattttggatgactgtgcaaattgtgttactctt
cctggggggcagctgaagaaaaattacgtggtctatgcttgtaaactaatggaaccgaca
ataaactgtggcaataagaacgggcaactgcagtgtgatcattgcagctcgctgcatgac
aaatacctgtgcttggaaagctcctgccggcagccccacatctgctcaggcgggggactt
tgcagggagggttctactcacagtccaccggccaagacttttctgggccctttggaggag
ttctctgacagttgtgacgatggagacgatttttttagaagcaagaaggaacggtccact
ctgttagtcagaaggttttgcaaaaatgacagggaagttaagaggtctgtgtatactggg
acaagagcaatcgtgagaaccctgccttctggccacattgggccagctgcttggaaccat
gttaatcagaagagagcaaggctcttagggccttttggggatttaatggaacctctgtca
gcgatggacataagaccacgtgggagccaatggctgtctgaagcccagtggtgtctgatc
tacagtgcagtgagaagaggagacgagacagaagatacggttggatctcttctccattgc
tccagacagctcccgacctccgagacagcctgtggaaggattagagatgctccatgctta
aagcaatgtgtacgagacaccgaatgtgagtaccgtgccaccctccaaaggacatccata
gctcagtacatcactggttctctcctggaggcaaccacctctctaggagcaagaagcggc
cttctcagtaccttcggaggatccactggacgaataatgctgaaagaacgccaacccggc
acctctatggccaattccaataccgttccttcaagttcagctgggatcagcaaggagctg
attgatctccagcccctcattcagttcccggaggaagtggccagcatcttgacagaacag
gagcagaacatttaccgaagggtcctgcccatagactacctttgtttcttaacccgggac
ttgagttcccctgaatgccagagttccctgccccgtctcaaagcatccatctcagcatca
atcctcacttctcagaatggagagcacaatgcccttgaagaccttgtgatgagatttaat
gaggtgagctcctgggtgacatggctgatcctcacagcaggctccatggaggagaagcgg
gaagtcttctcatacttggtgcatgtggccaaatgctgctggaacatgggcaactacaat
gctgtcatggagttcctggctggcctcaggtcaaggaaggttctgaagatgtggcagttt
atggatcagtctgacattgagaccatgcggagcttgaaggatgccatggctcagcatgag
tcttccctggagtacaagaaggttgtgacccgtgccctgcacatccctggctgcaaggtg
gttcccttctgtggggtgttcctgaaggagctctgtgaggtgcttgatggtgcctctggc
ctcctgaagctctgcccacggtacggctcccaagaagaagccctggagttcgtagccgac
tacagtggacaagataacttcttacagcgagtgggacagaacggcttgaagaattcagag
aaggagtccacagtcaacagcatctttcagatcatcaggagctgcagtcggagcttggag
atggaggaggaggacagccccagtgaaggggccggctccaggaaaaactccttgaaggat
aaagcccgatggcagtttataattggagatttgctggattcagaaaatgacatctttgag
aagtccaaagaatgcgaccctcatggatcagaggagtcacagaaagcctttgaccacggg
acagagctcatcccatggtacgtgctgtccatccaagctgatgtacaccagttcctattg
cagggggccacagtcatccactatgaccaggacacacatctctctgcccgatgctttctc
cagttacaacctgacaatagcaccttgacctggatgaagcctcccaccgcctcccccacc
ggtgccagacccaagcttggtatactcagtaatacgtctgagcctggcaagttcccatca
ctgggcagtgctgggctgagtggcctggctgagggaatcctggatctgttttcagtgaag
gctgtgtacatgggacacccaggcattgatatacacactgtgtgtgttcagaacaaactg
agtagcctgcttctctcagagactggggtgacattgctctatggacttcagaccaccgac
aatagactcttgcactttgtggcaccaaagcacacagctaaaatgcttttcagtggattg
ctggaactcacgacagctgtgagaaagataaggaagttccctgaccaaagacagcagtgg
cttcggaaacagtatgtcagcctctatcaggaggatggtcggtatgaaggcccaaccttg
gctcatgctgtggagttgtttggtggcagacgatggagcgctagaaaccccagccctggg
atgtcagcaaagaatgctgagaagcccaacatgcagagaaacaacaccctgggcataagc
accaccaagaaaaagaagaaaatgctcatgaggggagagagcggagaggccactgacgat
gagatggcgacgcgcaaggccaaaatgtacagagagtgtcgaagcaggagcggctctgat
cctcaggacgttaacgaacaggaagagtccgaagccaatgccatcgctagccctcccaac
tccctccattccagaagagctcactctttgaccacggctgggtcccccaacttggctacc
gggatgtcatctcccatcagtgcgtggagcagcagcagctggcatggtcggatcaaggga
ggaatgaagggtttccaaagcttcatggtttcagacagtaacatgagtttcattgaattt
gtcgaactgttcaaatcattcagcataaggagccgcaaggacctgaaggacatctttgac
atctactctgtgccctgcaatcggtctgcctctgagtccgcacccctgtacaccaacctg
accattgaagaaaacaccagtgaccttcagcctgacctagatttgctgaccagaaacgtc
tcagacttggggctgttcattaagagtaaacagcagctttctgacaaccagaggcagata
tctgatgccattgcagctgccagcattgtgactaatggcactgggattgagagcacatcc
ctgggcatatttggggttggcatcctccagctcaatgacttcctggtgaattgccaagga
gaacactgcacgtacgatgaaattctcagcatcatccagaaattcgagcctaacatcagt
atgtgccatcagggcctaatgtcgtttgaagggtttgcaaggtttctgatggataaagat
aatttcgcctcaaaaaatgatgagtcacgggagaacaagaaagaactgcaatttcctctc
tcctactattacatagaatcttcccacaatacctacctcacaggccatcagctcaaggga
gagtcctccgtggagctctacagtcaggtcctcttgcaaggatgcaggagcatagagcta
gactgctgggatggagatgacggcatgcccattatttatcacggacatacactgacgacc
aagatcccctttcaagtggtggaagccatcgaccgcagtgccttcatcacctctgacctg
ccaatcatcatatccattgagaaccactgttcattgcctcaacaacgaaaaatggcagac
attttcaagagtgtgtttggagaaaagctggtggccaaattcttattcgagaccgatttc
tcagatgacccaatgcttccctcacctgaccaacttaggaggaaagtgctccttaaaaac
aagaagctaaaggcccatcagacaccagtcgacatcctaaagcaaaaggctcatcagtta
gcatccatgcaagcacaggctttcactggtgggaatgccaaccccccacctgctagcaac
gaggaagaagaagatgaagaggatgaatacgattatgattatgaatccctttctgacgac
aatattctggaagacaaacctgaaaacaaatcgtgtgttgacaagcttcagtttgagtac
aatgaagaaatccccaaaaggataaagaaagcagataactcttcttgcaataagggaaag
gtgtatgacatggaactgggagaggagttttacctccctcagaacaagaaggaaagcagg
cagattgcaccggaactctctgacctcatcatctactgccaggcagtaaagtttccgggc
ctgtcaactctaaattcatctggctctagcagagggaaagaaaggaaaagcaggaagtcc
atttttggcaacaatcctggcagaatgagcccaggggagacagcatcgtttaacaggaca
tctggaaaaagttcctatgaaggaattcgacaaacctgggaggaatcgtcttctccactc
agcccaagcacatccctcagcgctatcattagaactcccaaatgctatcatatctcgtca
ctgaatgaaaatgccgccaaacgtctgtgtcgcaggtattctcagaaactgatccagcac
accgcttgtcagctgctgaggacctaccctgctgcaacccgaatcgactcatccaatccc
aaccccctcatgttctggctccacgggatacagcttgtagccctcaactaccagacggat
gatcttcctttacatttaaatgctgcaatgtttgaggcaaatggtggctgtggttatgtt
ttgaagccccctgtcctgtgggataaaagctgccccatgtatcagaagttctctccgctg
gaaagggacctagacaatatggaccctgccatctattctttaactatcatctctggccag
aatgtgtgccccagtaacagcaccggaagtccatgcattgaggttgacgtcttgggcatg
cccctggacagctgccacttccgcacaaagcccatccatcgaaacactctgaacccaatg
tggaacgaacagtttctcttccgggttcactttgaagatcttgtatttcttcgctttgca
gtcgtggaaaacaacagttcggcaataacggctcagagaatcattccactcaaagcttta
aaacgaggttatcgacatctgcagctgcggaacctccacaatgaaatattggaaatctct
agcttgttcataaacagcagaaggatggaggacaatccctctggcagtaccatgccagcc
tcttcgatgtttaatactgaagagaggaaatgttctcagacgcacagagtcacggtgcat
ggcgtcccaggaccagagccctttgctgtctttactataagtggaggcaccaaggcaaag
cagcttctccaacagattctggtgatggacaaagacaccaaacataccgccacagactat
tttctgatggaagagaagtattttatatctaaggaaaagagcgagtgcaagaaacaacca
ttccagagaactgtgggtccagaagaagatatcgtgcagattttaaacagctggttccca
gaagaaggctacgtaggcaggattgtcttaaagccccaacaggaaaccgtagaagagaaa
agcattgtccaagatgacaaggaggtgatcttgagctcggaggaggagagcttctttgtt
caagttcatgacgtctctccagagcaaccccgaactgtcatcaaagccccccgggtcagc
actgcacaggatgtcattcagcagaccttatgcaaagccaaatattcctacagcatcctg
aacaaccccaacccaggtgactatgtgcttctggaagaggtgatgaaagatgcacccaat
aagaagtcttctactccaaagtcctcccagaggatccttttggaccaagagtgtgtgttt
caagcccaaagcaagtggaaaggtgcagggaaattcatccttaagctaaaggagcaggtt
caggcatcccgagaagataaaagaaggggcatctcctttgcaagtgaactcaagaaactc
accaagtccactaagcagcctcgaggactcacatcgcctcctcagcttgtagcctcagaa
agtgtccaaattaaggaggagaaacctgtgggtgccttgtccnccagtgacacagtgggc
taccagcagtga
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integrated database retrieval system
