Parus major (Great Tit): 107202092
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Entry
107202092 CDS
T04864
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
pmaj
Parus major (Great Tit)
Pathway
pmaj00270
Cysteine and methionine metabolism
pmaj00480
Glutathione metabolism
pmaj01100
Metabolic pathways
pmaj01240
Biosynthesis of cofactors
pmaj04216
Ferroptosis
Module
pmaj_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
pmaj00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
107202092 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
107202092 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
107202092 (GCLC)
Enzymes [BR:
pmaj01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
107202092 (GCLC)
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GFIT
Motif
Pfam:
GCS
GCS2
SANT_DAMP1_like
Motif
Other DBs
NCBI-GeneID:
107202092
NCBI-ProteinID:
XP_015477865
Ensembl:
ENSPMJG00000009196
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Position
3:89818024..89854486
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AA seq
645 aa
AA seq
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MGLLSQGSPLSWEETRRYAEHVRRHGILQFLHIYRALRDRHKDVLKWGDEVEYMLVKFDH
ENKKVRLVLCGEEVVQTLQDRGEKVNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
QDNMRKRRQEAASVLKENEAVCTVTSFPSLDLIVLLHRLGCPGFTLPEYQPTPVEGGASK
SLFFPDEAINKHPRFSTLTRNIRHRRGEKVVINVPLFKDKNTPSPFIETFPNDDGEAAKA
AKPDYIYMDAMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYV
SDIDCRWGVISASVDDRTREERGLEPLKNSHYRISKSRYDSIDSYLSECGEKYNDIDLTI
DKDIYEHLIKEGIDHLLAQHIAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMR
FKPPPPNSDIGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENM
KVAQKRDAVRQGMFYFRKDICKGGNAVVDGCGSAQNGTGTDTEEYTLMSIDTIINGKEGV
FPGLIPILNSYLENMEVDVDTRCTILNYLKLIKKRASGELMTVARWMREFIAQHPDYKQD
SVITDEINYSLMWKCNQIAQGQAECPELLGVGFNKKQSGNKTDSL
NT seq
1938 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcgcagggctcgccgctgagctgggaggagacccggcggtacgcggag
cacgtgcggcggcacggcatcctccagttcctccacatctaccgcgccctgcgcgaccgc
cacaaggacgtgctcaagtggggcgacgaggtggaatatatgttggtaaaatttgaccat
gaaaataagaaagtgcgtttggtactctgtggtgaagaagttgttcaaacactgcaagac
agaggggagaaggtaaaccccaatcacccaacactctggagaccagaatatggaagttac
atgattgaaggaacacctggacagccatatggaggaaccatgtctgaattcaatactgtt
caagacaacatgaggaaaagacggcaagaggctgcttctgtactcaaagaaaatgaggct
gtttgcacagtgacatcatttccaagcttggatctcattgttctgttacacaggttaggg
tgccctgggtttacactgccagaatatcagccaacaccagtagaaggaggagcttcaaaa
tccctcttttttccagatgaagccatcaataaacatcctagatttagtacactgaccaga
aatattcgacaccgaagaggagagaaggttgtgataaacgtaccactatttaaggataag
aacacaccatcacctttcattgaaacatttcctaacgatgatggggaagcagcaaaggca
gctaagccggactacatatatatggatgctatgggttttggaatgggaaactgttgtctc
caggtaacatttcaagcttgcagcatttctgaagcaaggtatctctatgatcagctagct
acgatttgtcccattgtgatggcgttgagtgctgcatctcccttctacagaggctacgtg
tctgacattgactgtcgctggggagtgatctcagcttccgtggatgatcgaacgcgggag
gagagagggctagagccactgaagaacagccattatagaatcagtaaatccagatatgat
tccatagacagttatctatctgaatgtggtgagaaatacaatgacattgatttgacaata
gacaaagatatctacgagcacctaataaaggaaggtattgaccaccttttggcacagcat
attgcacacttgttcattcgagacccattgactttgtttgaggagaaaatacatctagat
gatgcaaatgaatccgaccattttgagaatattcagtctacaaactggcagacgatgaga
tttaagccaccacctccaaattcagatattggatggagagtggaattcagacctatggag
gtccagttaacagactttgaaaactctgcatatgttgtgtttgtggtattgctaaccaga
gtgattctgtcatataaactggattttctcattcctttgtccaaggtggatgaaaacatg
aaggtggcccagaaaagagatgccgtacgacagggaatgttctacttcagaaaagatata
tgcaaaggtggaaatgctgttgtggatggatgtggctctgcacagaatggaacaggcacc
gacacagaagagtacaccttaatgagcattgatacaattatcaatgggaaggaaggagtc
tttcctggtttgatcccaattttgaattcctatcttgaaaacatggaagtggatgtggac
acaagatgcaccatcctaaactatctgaagctaattaaaaagagagcttctggagaatta
atgacagttgctcgatggatgagggaattcattgcacagcatccggactacaagcaagac
agtgtgataactgatgaaattaattacagccttatgtggaaatgcaaccaaatcgctcaa
ggccaggcagagtgtcctgaactattgggggtaggatttaataagaaacaaagtggaaac
aaaactgactctttgtaa
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