Poecilia mexicana (shortfin molly): 106914801
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Entry
106914801 CDS
T08022
Symbol
gclc
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
pmei
Poecilia mexicana (shortfin molly)
Pathway
pmei00270
Cysteine and methionine metabolism
pmei00480
Glutathione metabolism
pmei01100
Metabolic pathways
pmei01240
Biosynthesis of cofactors
pmei04216
Ferroptosis
Module
pmei_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
pmei00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
106914801 (gclc)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
106914801 (gclc)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
106914801 (gclc)
Enzymes [BR:
pmei01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
106914801 (gclc)
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Paralog
GFIT
Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
106914801
NCBI-ProteinID:
XP_014837331
Ensembl:
ENSPMEG00000018095
UniProt:
A0A3B3YVE3
LinkDB
All DBs
Position
Unknown
AA seq
630 aa
AA seq
DB search
MGLLSQGSPLNWEETKKYADHIRKHGIIQFLNIYNKVKDRQRDVLKWGDEVEYMLVELDD
NDEKVRLVLNGGDVLETLQEQGENTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EGNMRKRRLEASSVLKKNMTLCTITSFPRLGCPGFTKPEYRPTPVEKGVSKSLFFPDEAI
NRHPRFSTLTRNIRHRRGEKVVINVPIYKDKNTPSPFVEQFPEDDGEAARAALPDHIYMD
AMGFGMGNCCLQVTFQACSIDEARYLYDQLATFCPIVMALSAASPFYRGYMSDIDCRWGV
ISASVDDRTQEERGLKPLKNNKYRIFKSRYDSIDSYLSCCGEKYNDIDLTIDEEINKQLL
GAGIDKLLAQHIAHLFIRDPLSVFEEKIHLDDENESDHFENLQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENAAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRNAV
QEGMFYFRKDMFKGCNPGLDCASSAQNGVEFEGNNEDYTLMSIDTIINGKEGVFQGLIPI
LNCYLENMEVDVDTRCTILNYLKLIKKRASGELMTMAKWMREFVAKHPEYKQDSVVTDKI
NYDLLKRCDRIAKGEEQCPELFGNPVNRVK
NT seq
1893 nt
NT seq
+upstream
nt +downstream
nt
atggggttactgtcgcaaggatctcccctgaactgggaagaaacaaagaagtatgccgac
cacatccgaaagcatggcatcatccagttcctcaacatctacaataaggtcaaggatcgt
cagagagatgtgttgaagtggggagacgaggttgagtacatgctggtggagctggacgac
aacgatgagaaagttcggctggtgctgaatggtggagatgttttggaaactctacaagaa
cagggagaaaatacaaacccaaatcatccgacactttggagaccggagtatggcagctac
atgatcgagggaactcctgggcagccgtacgggggaacgatgtcagagttcaacacggtg
gagggcaacatgaggaagagacgtctggaggcttcgtctgtcctgaagaagaatatgacg
ctctgcaccatcacctccttcccaaggttaggctgtccaggtttcaccaaaccagagtac
cgacccactcccgttgaaaaaggagtgtcaaagtctttgtttttcccagatgaagccata
aacagacaccccagattcagcaccctgaccagaaacatacggcaccgaagaggagagaaa
gttgtgataaatgtgccaatctacaaagataaaaacacaccgtctccattcgtggagcag
ttccctgaggacgacggtgaagcagcgagggcagcccttcctgaccacatctacatggac
gccatgggtttcggcatgggcaactgctgcctgcaagtgacattccaagcttgcagcatt
gatgaggcaaggtatctttatgaccaactagcaacattctgccccatcgtgatggcgctg
agcgctgcctcacccttctacagagggtacatgtctgatattgattgtcgctggggagtt
atctcagcctcggtggacgacaggacccaagaggaacgaggcctgaagcctctgaaaaac
aacaagtataggatctttaagtccaggtatgactcgattgacagctacctgtcttgctgc
ggggagaagtacaacgacatcgatttgacgatagacgaggagataaacaagcagctgctc
ggtgcagggattgacaagcttctggctcaacacatagctcacctcttcatacgagacccg
ctctccgtctttgaggagaaaatacatttggacgatgagaacgaatcggatcactttgag
aaccttcagtcgaccaactggcagacgatgcggttcaaacctccacctccgaactccgac
atcggctggagggtcgagtttcgccccatggaggttcagctaactgactttgaaaatgcc
gcatatgtggtttttgttgtcctgcttaccagagtgatcttatcctacaagctggatttc
ctaatccccttatcaaaggtggatgagaacatgaaggtggcacagaagagaaacgcagtc
caggagggcatgttttatttccgcaaagacatgtttaaaggctgcaacccaggcttggat
tgtgcttcttctgctcagaacggcgtagagtttgagggcaataacgaggattacacactg
atgagcatcgacacaatcatcaacgggaaggagggagtatttcaaggccttatcccaatc
cttaactgctatctggaaaacatggaagttgacgttgacaccaggtgcactattttaaat
tatctgaagctcatcaagaaacgtgcctcaggagaactgatgaccatggccaagtggatg
agggaatttgttgcaaagcaccccgagtacaagcaggacagtgtcgttaccgacaagatc
aactacgacttgctcaaaaggtgcgacaggattgctaaaggcgaagagcagtgccccgag
ctttttggtaacccagtcaaccgggtgaagtga
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