Proteus mirabilis HI4320: PMI1786
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Entry
PMI1786 CDS
T00753
Symbol
folC
Name
(GenBank) FolC bifunctional protein [includes: folylpolyglutamate synthase and dihydrofolate synthase]
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
pmr
Proteus mirabilis HI4320
Pathway
pmr00790
Folate biosynthesis
pmr01100
Metabolic pathways
pmr01240
Biosynthesis of cofactors
Module
pmr_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
pmr00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
PMI1786 (folC)
Enzymes [BR:
pmr01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
PMI1786 (folC)
6.3.2.17 tetrahydrofolate synthase
PMI1786 (folC)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
CAR43714
UniProt:
B4EZF4
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All DBs
Position
complement(1915680..1916978)
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AA seq
432 aa
AA seq
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MSNIITAPQATSPLSVWLSYLEHLHSSAIDMGLERVGKVGQLLNVLRPAPKVITVSGTNG
KGTTCHMLESILMASGLKVGVYSSPHLVRYTERVRIQGKELSPAEFCQVFAEIEQTRGDI
SLTFFEYGTLAALKLFQQAQLDVVILEVGLGGRLDATNIVDADIAAITSIALDHTDWLGA
DREHIGHEKAGIFRKNHYAVVGEPDMPLSIAQVAQQKQAKLFRRGVDWSFSIDGDHWHWR
SADKQFEKLPIPNIPLANAGTAMAVIRCLLKSDDKVSQGITHQSIVEGMSKAQLPGRFQI
ISQHPLVIFDVAHNPHAAGYLAEKLAQLPRYSDTKVRIVVGMLGDKDIAGTLACLSPQAD
QWYVAPLNEFRGASAQVLAQHLDYPAVFDSVEQAWQQAISEAQKNDIVVVCGSFHTVAHV
MELLEKESASGK
NT seq
1299 nt
NT seq
+upstream
nt +downstream
nt
atgtctaatatcataactgctcctcaagccacatcgcctttgtcggtgtggctttcttat
cttgaacacttacactcaagtgctattgatatgggacttgagcgcgtgggcaaggtaggt
caattactgaatgtattacgtcctgcccctaaagttatcactgtatcgggtactaatggt
aaaggaaccacttgccatatgctcgagtcaattttgatggcttcaggattgaaagtgggg
gtttatagttcacctcatcttgtccgttataccgagcgtgttcgcattcaaggtaaagag
ctttcaccagctgagttttgtcaagtatttgctgaaatagagcaaaccagaggcgatatt
tcgctgactttttttgaatacggcacactcgccgcattgaaactatttcaacaagctcag
cttgatgtggttattcttgaagttgggttaggggggcgtttagacgcgaccaatattgtt
gatgccgatattgcagctatcaccagtattgcccttgatcataccgattggttaggggct
gatagagagcatattggtcatgaaaaagccggtatcttccgtaaaaatcactatgctgtt
gtaggcgagccagatatgccactgtctattgcacaagtcgcgcaacagaaacaggctaaa
ttatttcgtcgtggtgttgattggtcattttctattgatggtgatcactggcattggcgt
agtgcagataagcagtttgaaaaacttcccatccctaatattcccttagccaacgcaggt
acggcaatggcagtaatacgctgcttattgaaaagcgacgataaagtgagccaagggatc
acccatcaaagtattgttgagggaatgagtaaagctcagttgccgggacgttttcagata
atttcgcagcatccattagttatttttgatgttgctcataatccgcatgctgctggatat
ttagccgaaaaactggcgcaattaccgcgttattctgataccaaagtgcgcattgttgtt
ggtatgctgggtgataaagatattgcgggtacattagcgtgtttatcccctcaagccgat
cagtggtatgttgcaccattgaatgagtttcgtggcgcatcagctcaggtattagctcag
cacctcgactatccggcagtatttgatagtgtcgagcaagcatggcaacaagcaatatct
gaggcgcaaaaaaatgatattgtggttgtatgtggatcattccataccgttgctcatgta
atggaactattggaaaaggagagtgcgagtggcaagtaa
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