Petromyzon marinus (sea lamprey): 116953902
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Entry
116953902 CDS
T09614
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit-like isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
pmrn
Petromyzon marinus (sea lamprey)
Pathway
pmrn00270
Cysteine and methionine metabolism
pmrn00480
Glutathione metabolism
pmrn01100
Metabolic pathways
pmrn01240
Biosynthesis of cofactors
pmrn04216
Ferroptosis
Module
pmrn_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
pmrn00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
116953902
09106 Metabolism of other amino acids
00480 Glutathione metabolism
116953902
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
116953902
Enzymes [BR:
pmrn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
116953902
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Motif
Pfam:
GCS
Motif
Other DBs
NCBI-GeneID:
116953902
NCBI-ProteinID:
XP_032830097
EnsemblRapid:
ENSPMAG00000006848
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All DBs
Position
53:complement(1831252..1866724)
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AA seq
626 aa
AA seq
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MGPQLRGSILRWSDAKAQAEFVRARGLQQLVRCLTRRGHGDHPLLWGDEVEYMLVSFDHV
ARRARVLLSAEELVNDLIAMDEEANLGHPSRWHLEFSSYMLEGIPAQPYGSSIAELTSVE
TSMRLRRRDVLARLRANETICSLTTFPRLGCPGFTQPEYVPQHRDGITASLFLPDEVITS
HSRFSAIARNIHDRRGEKIVVNVPIFRDRNTPSPFIDQIPPGDEEAAIAVKADHIYMDAV
GFGSGNCCLQVTLQARNMEEARHIYDQLAVMCPIMMALSAAAPFYRGLVSDVDCRWSINS
AACDDRTRQERGLEPLTTCKRRITKSRFDSIDSFLSPGGAQFNDLELPKDEDVHLQLLDA
GIDPLLAQHFAHLFIRDPLVMLWEKIHVDDDENEAYHFECIQSTNWQTLRLKLPPPNTSI
GWLVEFRPMDVQLTDFENAAYVVFVVLLTRVILSYGLNFLVPLSKVDENITKAQKRNAVL
EEMFYFRKDIQAEVDALPADGTASEDEVGILMSINTVINGKVGVFQGLVPIVNSFLEDME
VDVETRCTISHYLELISKRASGELGTTAQRLRAFVSGHPDYAHDSVISERVNYDLLLRCD
ALARARPHGHGTDPLHELSHGACQTG
NT seq
1881 nt
NT seq
+upstream
nt +downstream
nt
atggggccgcaactgagaggctcgatcctgcgctggagcgacgcgaaggcgcaggcggag
ttcgtgcgcgcgcgcggcctgcagcagctcgtgcggtgcctcacgcggcggggccacggg
gaccacccgctcctgtggggcgacgaggtcgagtacatgctcgtctcctttgatcacgtg
gcgcgcagggcccgcgtcctgttgagcgcagaggagctggtcaatgacttgatagccatg
gacgaggaggccaacctggggcacccgtcacggtggcacttggagtttagcagctacatg
ctggaggggatcccagcacagccgtacggaagctccatcgccgagctgaccagcgttgag
acgagcatgaggctgcgacggagggacgtgctggctcggctgcgcgcgaacgagacaata
tgctccctcaccaccttccccaggctcggctgcccgggtttcactcaacccgagtatgtg
ccccagcaccgagacggaataactgcgtcactgttcttgccggacgaggttatcaccagc
cactcgcgcttcagcgcgattgcgaggaacatccacgataggagaggagagaagatcgtg
gtgaacgtaccgatcttcagggacagaaacactccatccccattcatcgaccaaattccg
cccggtgacgaggaagcggccatcgcggtgaaggccgaccacatttacatggacgcggtg
ggattcggatcgggaaactgctgcctccaggtcacactgcaggctagaaacatggaagaa
gcgcgacatatctacgaccagctggctgttatgtgccccatcatgatggccctcagcgcc
gccgcccccttctaccgggggctcgtgtcggacgttgactgccgctggagcatcaactcc
gccgcatgcgacgaccgcacgcgacaggagagagggctcgagcccctcacaacatgcaag
aggcgaatcaccaagtcacggtttgactccatcgacagcttcctgtcacccggcggagcg
cagttcaatgatctggagttgcccaaggacgaggacgtccacctgcagctcctggatgca
ggcatcgatccgctgctcgctcagcactttgctcacctcttcatccgtgaccccctcgtg
atgctctgggagaagatccacgtcgatgacgatgagaacgaggcctaccactttgaatgc
atccagtccacaaactggcagacgttgcgcttaaagcttccgccgccgaacaccagcatc
gggtggctcgtcgagttccggccgatggacgtgcagctcacagactttgagaacgcagca
tacgtggtgttcgtggtgctgctcacgcgcgtcatcctctcctatggcctcaacttcctc
gtgccgctctccaaggtagatgagaacatcacgaaggcgcagaagaggaacgcggtgctg
gaggagatgttttatttcaggaaggacattcaggcagaggtggacgctctcccagcggac
ggcactgcgtccgaggacgaggtggggatcctcatgagtattaacaccgtcatcaacggc
aaggtgggggtgttccagggcctcgtccccatagtcaacagcttcctggaggacatggag
gtggacgtggagactcggtgcacgatctcccactacttggagctcatcagcaagcgcgcg
tccggggagctggggacgacggcccagcggctgcgcgccttcgtgagcggccaccccgac
tacgcgcacgacagcgtaatctcggagcgcgtcaactacgacctgctgctgcgctgcgac
gccctggcgcgtgcgcggccccacggccacggcacggaccccttgcacgagctcagccac
ggtgcttgccagaccggctag
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