Pongo abelii (Sumatran orangutan): 100435220
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Entry
100435220 CDS
T01416
Symbol
ACVR2A
Name
(RefSeq) activin receptor type-2A
KO
K04670
activin receptor type-2A [EC:
2.7.11.30
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon04060
Cytokine-cytokine receptor interaction
pon04350
TGF-beta signaling pathway
pon04550
Signaling pathways regulating pluripotency of stem cells
pon05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
100435220 (ACVR2A)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
100435220 (ACVR2A)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
100435220 (ACVR2A)
09160 Human Diseases
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
100435220 (ACVR2A)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pon01001
]
100435220 (ACVR2A)
Enzymes [BR:
pon01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.30 receptor protein serine/threonine kinase
100435220 (ACVR2A)
Protein kinases [BR:
pon01001
]
Receptor serine/threonine kinases (RSTK): TKL group
TGFBR2 family [OT]
100435220 (ACVR2A)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Pkinase_fungal
Activin_recp
FTA2
Motif
Other DBs
NCBI-GeneID:
100435220
NCBI-ProteinID:
XP_009235972
Ensembl:
ENSPPYG00000012834
UniProt:
A0A6D2WUX0
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Position
2B:33654834..33742897
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AA seq
513 aa
AA seq
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MGAAAKLAFAVFLISCSSGAILGRSETQECLFFNANWEKDRTNQTGVEPCYGDKDKRRHC
FATWKNISGSIEIVKQGCWLDDINCYDRTDCVEKKDSPEVYFCCCEGNMCNEKFSYFPEM
EVTQPTSNPVTPKPPYYNILLYSLVPLMLIAGIVICAFWVYRHHKMAYPPVLVPTQDPGP
PPPSPLLGLKPLQLLEVKARGRFGCVWKAQLLNEYVAVKIFPIQDKQSWQNEYEVYSLPG
MKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFLKANVVSWNELCHIAETMARGL
AYLHEDIPGLKDGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSAGDTHGQV
GTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELASRCTAADGPVDEYMLPFEEEIG
QHPSLEDMQEVVVHKKKRPVLRDYWQKHAGMAMLCETIEECWDHDAEARLSAGCVGERIT
QMQRLTNIITTEDIVTVVTMVTNVDFPPKESSL
NT seq
1542 nt
NT seq
+upstream
nt +downstream
nt
atgggagctgctgcaaagttggcgtttgccgtctttcttatctcctgttcttcaggtgct
atacttggtagatcagaaactcaggagtgtcttttctttaatgctaattgggaaaaagac
agaaccaatcaaactggtgttgaaccgtgttatggtgacaaagataaacggcggcattgt
tttgctacctggaagaatatttctggttccattgaaatagtgaaacaaggttgttggctg
gatgatatcaactgctacgacaggactgattgtgtagaaaaaaaagacagccctgaagta
tatttttgttgctgtgagggcaatatgtgtaatgaaaagttttcttattttccggagatg
gaagtcacacagcccacttcaaatccagttacacctaagccaccctattacaacatcctg
ctctattccttggtgccacttatgttaattgcggggattgtcatttgtgcattttgggtg
tacaggcatcacaagatggcctaccctcctgtacttgttccaactcaagacccaggacca
cccccaccttctccattactaggtttgaaaccactgcagttattagaagtaaaagcaagg
ggaagatttggttgtgtctggaaagcccagttgcttaacgaatatgtggctgtcaaaata
tttccaatacaggacaaacagtcatggcaaaatgaatacgaagtctacagtttgcctgga
atgaagcatgagaacatattacagttcattggtgcagaaaaacgaggcaccagtgttgat
gtggatctttggctgatcacagcatttcatgaaaagggttcactatcagactttcttaag
gctaatgtggtctcttggaatgaactgtgtcatattgcagaaaccatggctagaggattg
gcatatttacatgaggatatacctggcctaaaagatggccataaacctgccatatctcac
agggacatcaaaagtaaaaatgtgctgttgaaaaacaacctgacagcttgcattgctgac
tttgggttggccttaaaatttgaggctggcaagtctgcaggcgatacccatggacaggtt
ggtacccggaggtacatggctccagaggtattagagggtgctataaacttccaaagggat
gcatttttgaggatagatatgtacgccatgggattagtcctatgggaactggcttctcgc
tgtactgctgcagatggacctgtagatgaatacatgttgccatttgaggaggaaattggc
caacatccatctcttgaagacatgcaggaagttgttgtgcataaaaaaaagaggcctgtt
ttaagagattattggcagaaacatgctggaatggcaatgctctgtgaaaccattgaagaa
tgttgggatcatgacgcagaagccaggttatcagctggatgtgtaggtgaaagaattacc
cagatgcagagactaacaaatattattaccacagaggacattgtaacagtggtcacaatg
gtgacaaatgttgactttcctcccaaagaatctagtctatga
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