Pongo abelii (Sumatran orangutan): 100446505
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Entry
100446505 CDS
T01416
Symbol
PDE2A
Name
(RefSeq) cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X1
KO
K18283
cGMP-dependent 3',5'-cyclic phosphodiesterase [EC:
3.1.4.17
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon00230
Purine metabolism
pon01100
Metabolic pathways
pon04022
cGMP-PKG signaling pathway
pon04740
Olfactory transduction
pon04925
Aldosterone synthesis and secretion
pon05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100446505 (PDE2A)
09130 Environmental Information Processing
09132 Signal transduction
04022 cGMP-PKG signaling pathway
100446505 (PDE2A)
09150 Organismal Systems
09152 Endocrine system
04925 Aldosterone synthesis and secretion
100446505 (PDE2A)
09157 Sensory system
04740 Olfactory transduction
100446505 (PDE2A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
100446505 (PDE2A)
Enzymes [BR:
pon01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
100446505 (PDE2A)
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
Motif
Other DBs
NCBI-GeneID:
100446505
NCBI-ProteinID:
XP_009245082
Ensembl:
ENSPPYG00000003652
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All DBs
Position
11:complement(64548190..64616134)
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AA seq
933 aa
AA seq
DB search
MVLVLHHILIAVVQFLRRGQQVFLKPDEPPPPQPCADSLQDALLSLGSVIDISGLQRAVK
EALSAVLPRVETVYTYLLDGESRLVCEDPPHELPQEGKVREAIICRKRLGCNGLGFSDLP
GKPLARLVAPLAPDTQVLVMPLVDKEAGAVAAVILVHCGQLRDSEEWSLQAVEKHTLVAL
RRVQALQQRGPREAPRAVQNPPEGAAEDQKGGAAYTDRDRKILQLCGELYDLDASSLQLK
VLQYLQQETRASRCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTGCLGQVVEDKKSIQL
KDLTSEDVQQLQSMLGCELQAMLCVPVISRATDQVVALACAFNKLEGDLFTDEDEQVIQH
CFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAE
ICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFY
RGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISI
AHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYTPR
SLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFC
YLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMER
HHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAQVGY
DRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMM
DREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLP
SNNSLDFLDEEYEVPDLDGTRAPINGCCSLDAE
NT seq
2802 nt
NT seq
+upstream
nt +downstream
nt
atggtcctggtgctgcaccacatcctcatcgctgttgtccaattcctcaggcggggccag
caggtcttcctcaagccggacgagccgccgccgccgcagccatgcgccgacagcctgcag
gacgctttgctgagtctgggctctgtcatcgacatttcaggcctgcaacgtgctgtcaag
gaggccctgtcagctgtgctcccccgagtggaaactgtctacacctacctgctggatggg
gagtcccggctggtgtgtgaggaccccccacatgagctgccccaggaggggaaagtccgg
gaggctatcatctgccggaagcggctgggctgcaatgggctgggcttctcagacctgcca
gggaagcccttggccaggctggtggctccactggctcctgatacccaagtgctggtcatg
ccgctagtggacaaggaggccggggccgtggcagctgtcatcttggtgcactgtggccag
ctgcgtgacagtgaggaatggagcctgcaggcagtggagaagcataccctggtggccctg
aggagggtgcaggccctgcagcagcgcgggcccagggaggctccccgagcggtccagaac
cccccggagggggcggcggaagaccagaagggcggggcggcgtacaccgaccgcgaccgc
aagatcctgcaactgtgcggggaactctacgacctggatgcctcttccctgcagctcaaa
gtgctccaatacctgcagcaggagacccgggcatcccgctgctgcctcctgctggtgtcg
gaggacaatctccagctttcttgcaaggtcatcggagacaaagtgctcggagaagaggtc
agctttcccttgacaggatgcctgggccaggtggtggaagacaagaagtccatccagctg
aaagacctcacctctgaggatgtacaacagctgcagagcatgttgggctgtgagctgcag
gccatgctctgtgtccctgtcatcagccgggccactgaccaggtggtggccttggcctgc
gccttcaacaagctagaaggagacttgttcaccgacgaggacgagcaggtgatccagcac
tgcttccactacaccagcaccgtgctcaccagcaccctggccttccagaaggaacagaaa
ctcaagtgtgagtgccaggctcttctccaagtggcaaagaacctcttcacccacctggat
gacgtctctgtcctgctccaggagatcatcacggaggccagaaacctcagcaacgcagag
atctgctctgtgttcctgctggatcagaatgagctggtggccaaggtgttcgacgggggc
gtggtggatgatgagagctatgagatccgcatcccggccgatcagggcatcgcgggacac
gtggcgaccacgggccagatcctgaacatccctgacgcatatgcccatccgcttttctac
cgcggcgtggacgacagcaccggcttccgcacgcgcaacatcctctgcttccccatcaag
aacgagaaccaggaggtcatcggtgtggccgagctggtgaacaagatcaatgggccgtgg
ttcagcaagttcgacgaggacctggcgacggccttctccatctactgcggcatcagcatc
gcccattctctcctatacaaaaaagtgaatgaggctcagtatcgcagccacctggccaat
gagatgatgatgtaccacatgaaggtctccgacgatgagtataccaaacttctccatgat
gggatccagcctgtggctgccattgactccaattttgcaagtttcacctatacccctcgt
tccctgccagaggatgacacgtccatggccatcctgagcatgctgcaggacatgaatttc
atcaacaactacaaaattgactgcccgaccctggcccggttctgtttgatggtgaagaag
ggctaccgggatcccccctaccacaactggatgcacgccttttctgtctcccacttctgc
tacctgctctacaagaacctggagctcaccaactacctcgaggacatcgagatctttgcc
ttgtttatttcctgcatgtgtcatgacctggaccacagaggcacaaacaactctttccag
gtggcctcgaaatctgtgctggctgcgctctacagctctgagggctccgtcatggagagg
caccactttgctcaggccatcgccatcctcaacacccacggctgcaacatctttgatcat
ttctcccggaaggactatcagcgcatgctggatctgatgcgggacatcatcttggccaca
gacctggcccaccatctccgcatcttcaaggacctccagaagatggctcaggtgggctat
gaccgaaacaacaagcagcaccacagactcctcctctgcctcctcatgacctcctgtgac
ctctctgaccagaccaagggctggaagaccacgagaaagatcgcggagctgatctacaaa
gaattcttctcccagggagacctggagaaggccatgggcaacaggccgatggagatgatg
gaccgggagaaggcctatatccctgagctgcaaatcagcttcatggagcacattgcaatg
cccatctacaagctgttgcaggacctgttccccaaagcagcagagctgtacgagcgcgtg
gcctccaaccgtgagcactggaccaaggtgtcccacaagttcaccatccgcggcctccca
agtaacaactcgctggacttcctggatgaggagtacgaggtgcctgatctggatggcact
agggcccccatcaatggctgctgcagccttgatgctgagtga
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