Pongo abelii (Sumatran orangutan): 100448480
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Entry
100448480 CDS
T01416
Symbol
IKBKE
Name
(RefSeq) inhibitor of nuclear factor kappa-B kinase subunit epsilon
KO
K07211
inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:
2.7.11.10
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon04620
Toll-like receptor signaling pathway
pon04621
NOD-like receptor signaling pathway
pon04622
RIG-I-like receptor signaling pathway
pon04623
Cytosolic DNA-sensing pathway
pon04625
C-type lectin receptor signaling pathway
pon04657
IL-17 signaling pathway
pon04936
Alcoholic liver disease
pon05160
Hepatitis C
pon05161
Hepatitis B
pon05162
Measles
pon05164
Influenza A
pon05165
Human papillomavirus infection
pon05167
Kaposi sarcoma-associated herpesvirus infection
pon05168
Herpes simplex virus 1 infection
pon05169
Epstein-Barr virus infection
pon05171
Coronavirus disease - COVID-19
pon05207
Chemical carcinogenesis - receptor activation
pon05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
100448480 (IKBKE)
04621 NOD-like receptor signaling pathway
100448480 (IKBKE)
04622 RIG-I-like receptor signaling pathway
100448480 (IKBKE)
04623 Cytosolic DNA-sensing pathway
100448480 (IKBKE)
04625 C-type lectin receptor signaling pathway
100448480 (IKBKE)
04657 IL-17 signaling pathway
100448480 (IKBKE)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
100448480 (IKBKE)
09172 Infectious disease: viral
05161 Hepatitis B
100448480 (IKBKE)
05160 Hepatitis C
100448480 (IKBKE)
05171 Coronavirus disease - COVID-19
100448480 (IKBKE)
05164 Influenza A
100448480 (IKBKE)
05162 Measles
100448480 (IKBKE)
05168 Herpes simplex virus 1 infection
100448480 (IKBKE)
05167 Kaposi sarcoma-associated herpesvirus infection
100448480 (IKBKE)
05169 Epstein-Barr virus infection
100448480 (IKBKE)
05165 Human papillomavirus infection
100448480 (IKBKE)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100448480 (IKBKE)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100448480 (IKBKE)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pon01001
]
100448480 (IKBKE)
Enzymes [BR:
pon01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.10 IkappaB kinase
100448480 (IKBKE)
Protein kinases [BR:
pon01001
]
Serine/threonine kinases: Other
IKK family [OT]
100448480 (IKBKE)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
TBK1_CCD1
Pkinase
TBK1_ULD
PK_Tyr_Ser-Thr
ABC1
Pkinase_fungal
Kinase-like
RH_dom
Motif
Other DBs
NCBI-GeneID:
100448480
NCBI-ProteinID:
XP_002809594
Ensembl:
ENSPPYG00000000288
UniProt:
A0A6D2Y6J8
LinkDB
All DBs
Position
1:complement(43072956..43098980)
Genome browser
AA seq
716 aa
AA seq
DB search
MQSTANYLWHTDDLLGQGATASVYKARNKKSGELVAVKVFNTTSYLRPREVQVREFEVLR
KLNHQNIVKLFAVEETGGSRQKVLVMEYCSSGSLLSVLESPENAFGLPEDEFLVVLRCVV
AGMNHLRENGIVHRDIKPGNIMRLVGEEGQSIYKLTDFGAARELDDDEKFVSVYGTEEYL
HPDMYERAVLRKPQQKAFGVTVDLWSIGVTLYHAATGSLPFIPFGGPRRNKEIMHRITTE
KPAGAIAGAQRRENGPLEWSYTLPITCQLSLGLQSQLVPILANILEVEQAKCWGFDQFFA
ETSDILQRVVVHVFSLSQAVLHHIYIHAHNTIAIFQEAVHKQTSVAPRHQEYLFEGHLCV
LEPSVSAQHIAHTTASSPLTLFSTAIPKGLAFRDPALDIPKFVPKVDLQADYNTAKGVLG
AGYQALRLARALLDGQELMLRGLHWVMEVLQATCRRTLEVARTSLLYLSSSLGTERFSSV
AGTPEIQELKAAAELRSRLRTLAEVLSRCSQNITETQESLSSLSRELVKSRDQVHEDRSI
QQIQCCLDKMNFIYKQFKKSRMRPGLGYNEEQIHKLDKVNFSHLAKRLLQVFQEECVQKY
QASLVTHGKRMRVVHETRNHLRLVGCSVAACNTEAQGVQESLSKLLEELSHQLLQDRAKG
AQASPPPIAPYPSPTRKDLLLHMQELCEGMKLLASDLLDNNRIIERLNTVPAPPDV
NT seq
2151 nt
NT seq
+upstream
nt +downstream
nt
atgcagagcacagccaattacctgtggcacacagacgacctgctggggcagggggccact
gccagtgtgtacaaggcccgcaacaagaaatccggagagctggttgctgtgaaggtcttc
aacaccaccagctacctgcggcctcgcgaggtgcaggtgagggagtttgaggtcctgcgg
aagctgaaccaccagaacatcgtcaagctctttgcggtggaggagacggggggaagccgg
cagaaggtactggtgatggagtactgctccagtgggagcctgctgagcgtgctggagagc
cctgagaacgcctttgggctgcctgaggatgagttcctggtggtgctgcgctgtgtggtg
gccggcatgaaccacctgcgggagaacggcatcgtgcatcgcgacatcaagcccgggaac
atcatgcgcctcgtgggggaggaggggcagagcatctacaagctgacagacttcggggcc
gcccgggagctggatgatgatgagaagttcgtctcggtctacgggactgaggagtacctg
catcccgacatgtatgaacgggcggtgcttcgaaagccccagcaaaaagcgttcggggtg
actgtggatctctggagcattggagtgaccttgtaccatgcagccactggcagcctgccc
ttcatccccttcggtggaccccggcggaacaaggagatcatgcaccggatcaccacagag
aagccggctggggccattgcaggtgcccagaggagggagaacgggcccctggagtggagc
tacaccctccccatcacctgccagctgtcactggggctgcagagccagctggtgcccatc
ctggccaacatcctggaggtggagcaggccaagtgctggggcttcgaccagttctttgcg
gagaccagtgacatcctgcagcgagttgtcgtccatgtcttctccctgtcccaggcagtc
ctgcaccacatctatatccatgcccacaacacgatagccattttccaggaggccgtgcac
aagcagaccagtgtggccccccggcaccaggagtacctctttgagggtcacctctgtgtc
ctcgagcccagcgtctcagcacagcacatcgcccacacgacagcaagcagccccctgacc
cttttcagcacagccatccccaaggggctggccttcagggaccctgctctggacatcccc
aagttcgtccccaaagtggacctgcaggcggattacaacacggccaagggtgtgttgggc
gccggctaccaggccctgcggctggcgcgggccctgctggatgggcaggagctaatgttg
cgggggctgcactgggtcatggaggtgctccaggccacatgcagacggactctggaagtg
gcaaggacatccctcctctacctcagcagcagcctgggaaccgagaggttcagcagcgtg
gctggaacacctgagatccaggaactgaaggcggccgcagaactgaggtccaggctgcgg
actctagctgaggtcctctccagatgctcccaaaatatcacggagacccaggagagcctg
agcagcctgagccgggagctggtgaagagccgggatcaggtacatgaggacagaagcatc
cagcagattcagtgctgcttggacaagatgaacttcatctacaaacagttcaagaagtct
aggatgaggccagggcttggctacaacgaggagcagattcacaagctggataaggtgaat
ttcagtcatttagccaaaagactcctgcaggtgttccaggaggagtgcgtgcagaagtat
caagcgtccttagtcacgcacggcaagaggatgagggtggtgcacgagaccaggaaccac
ctgcgcctggtcggctgttctgtggctgcctgtaacacagaagcccagggggtccaggag
agtctcagcaagctcctggaagagctatctcaccagctccttcaggaccgagcaaagggg
gctcaggcctcgccgcctcccatagctccttaccccagccctacacgaaaggacctgctt
ctccacatgcaagagctctgcgaggggatgaagctgctggcgtctgacctcctggacaac
aaccgcatcatcgaacggctaaatacagtcccagcacctcctgatgtctga
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