Pongo abelii (Sumatran orangutan): 100459152 Help Entry 100459152         CDS       T01416                                  Symbol GCK Name (RefSeq) glucokinase isoform X1   KO K12407   glucokinase [EC:2.7.1.2] Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon00010   Glycolysis / Gluconeogenesis pon00052   Galactose metabolism pon00500   Starch and sucrose metabolism pon00520   Amino sugar and nucleotide sugar metabolism pon00524   Neomycin, kanamycin and gentamicin biosynthesis pon01100   Metabolic pathways pon01200   Carbon metabolism pon01250   Biosynthesis of nucleotide sugars pon04910   Insulin signaling pathway pon04911   Insulin secretion pon04917   Prolactin signaling pathway pon04922   Glucagon signaling pathway pon04930   Type II diabetes mellitus pon04950   Maturity onset diabetes of the young pon05230   Central carbon metabolism in cancer Module pon_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate pon_M00549   Nucleotide sugar biosynthesis, glucose => UDP-glucose pon_M00892   UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc Brite KEGG Orthology (KO) [BR:pon00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     100459152 (GCK)    00052 Galactose metabolism     100459152 (GCK)    00500 Starch and sucrose metabolism     100459152 (GCK)    00520 Amino sugar and nucleotide sugar metabolism     100459152 (GCK)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     100459152 (GCK)  09150 Organismal Systems   09152 Endocrine system    04911 Insulin secretion     100459152 (GCK)    04910 Insulin signaling pathway     100459152 (GCK)    04922 Glucagon signaling pathway     100459152 (GCK)    04917 Prolactin signaling pathway     100459152 (GCK)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     100459152 (GCK)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     100459152 (GCK)    04950 Maturity onset diabetes of the young     100459152 (GCK) Enzymes [BR:pon01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.2  glucokinase      100459152 (GCK) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 Sec2p Motif Other DBs NCBI-GeneID:  100459152 NCBI-ProteinID:  XP_002818041 Ensembl:  ENSPPYG00000017596 UniProt:  A0A2J8ST49 LinkDB All DBs Position 7:29253081..29299053 Genome browser AA seq 466 aa AA seqDB search MAMDVTRSQVQTALTLVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLP TYVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTA EMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGN NVVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEME NVELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMG ELVRLVLLRLVDENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRP STTDCDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSF KERFHASVRRLTPSCEITFIESEEGSGRGAALVSAVACKKACMLGQ NT seq 1401 nt NT seq  +upstreamnt  +downstreamnt atggcgatggatgtcacaaggagccaggtccagacagccttgactctggtagagcagatc ctggcagagttccagctgcaggaggaggacctgaagaaggtgatgagacggatgcagaag gagatggaccgtggcctgaggctggagacccatgaagaggccagtgtgaagatgttgccc acctacgtgcgctccaccccagaaggctcagaagtcggggacttcctctccctggacctg ggtggcactaacttcagggtgatgctggtgaaggtgggagaaggtgaggaggggcagtgg agcgtgaagaccaaacaccagatgtactccatccccgaggacgccatgaccggcactgct gagatgctcttcgactacatctccgagtgcatctccgacttcctggacaagcatcagatg aagcacaagaagctgcccctgggcttcaccttctcctttcctgtgaggcacgaagacatc gataagggcatccttctcaactggaccaagggcttcaaggcctcaggagcagaagggaac aatgtcgtggggcttctgcgagacgccatcaaacggagaggggactttgaaatggatgtg gtggcaatggtgaatgacacggtggccacgatgatctcctgctactatgaagaccatcag tgcgaggtcggcatgattgtgggtacaggctgcaatgcctgctacatggaggagatggag aatgtggagctggtggagggggacgagggccgcatgtgcgtcaacactgagtggggcgcc ttcggggactccggcgagctggacgagttcctgctggagtatgaccgcctggtggacgag agctctgcaaaccccggtcagcagctgtatgagaagctcataggtggcaagtacatgggc gagctggtgcggctcgtgctgctcagactagtggacgaaaacctgctcttccacggggag gcctccgagcagctgcgcacacgcggagccttcgagacgcgcttcgtgtcgcaggtggag agcgacacgggcgaccgcaagcagatctacaacatcctgagcacgctggggctgcgaccc tcgaccaccgactgtgacatcgtgcgccgcgcctgcgagagcgtgtctacgcgcgctgcg cacatgtgctcggcggggctggcgggtgtcatcaatcgcatgcgcgagagccgcagcgag gacgtaatgcgcatcactgtgggcgtggatggctccgtgtacaagctgcaccccagcttc aaggagcggttccacgctagcgtgcgcaggctgacgcccagctgcgagatcaccttcatc gagtcggaggagggcagtggccggggcgcagccctggtctcggcggtggcctgtaagaag gcctgcatgctgggccagtga

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