Komagataella phaffii: PAS_chr2-1_0368
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Entry
PAS_chr2-1_0368 CDS
T01092
Name
(RefSeq) Isopropylmalate isomerase, catalyzes the second step in the leucine biosynthesis pathway
KO
K01702
3-isopropylmalate dehydratase [EC:
4.2.1.33
]
Organism
ppa
Komagataella phaffii
Pathway
ppa00290
Valine, leucine and isoleucine biosynthesis
ppa01100
Metabolic pathways
ppa01110
Biosynthesis of secondary metabolites
ppa01210
2-Oxocarboxylic acid metabolism
ppa01230
Biosynthesis of amino acids
Module
ppa_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
ppa00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
PAS_chr2-1_0368
Enzymes [BR:
ppa01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
PAS_chr2-1_0368
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GFIT
Motif
Pfam:
Aconitase
Aconitase_C
Motif
Other DBs
NCBI-GeneID:
8199056
NCBI-ProteinID:
XP_002491269
UniProt:
C4R0G5
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Position
2:complement(680824..683175)
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AA seq
783 aa
AA seq
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MPSTGEIKNPKTLYDKVFEDHVVHKDESGSYLLYIDRHLVHEVTSPQAFEGLKNAGRVVR
RKDCTLATVDHNIPTDSRKNLTTLDKFIKQDDSRLQVKTLEQNVKDFDVTYFGMKDSRQG
IVHVVGPEQGFTLPGTTVVCGDSHTSTHGAFGSLAFGIGTSEVEHVLATQTIIQAKSKNM
RITIEGELDEGITSKDLVLHVIGVIGTAGGTGSVIEFAGKAIEDLTMEARMSICNMAIEA
GARAGMIRPDETTFKYIEGRPLAPKGEQWTKALNYWKTLYSDEGAKFDYEIVIKAKDIVP
TITWGTSPQDALPITASVPDPEKVEDPIKKSGMERALSYMGLTPNVPLKDIKIDKVFIGS
CTNSRLEDLRAAAKVVKGHKKSDNVKLALVVPGSGLIKLQAEKEGLDKIFEEAGFSWREA
GCSMCLGMNPDILDPEERCASTSNRNFEGRQGARSRTHLMSPAMAAAAGIAGHFVDIREF
EYKEDKSQPKIAIQSEEDAELQDAVYEHEKKPLAEGESKDELEEDEIKDIPPPDHTVQET
PLKTSAPAVAAAMEKFLTVEGIAAPLDKANVDTDAIIPKQFLKTIKRTGLKAGLFYELRF
VKDDQGKDVETDFVLNVEPYRSASILCVTGDNFGCGSSREHAPWALKDFGIRSIIAPSFG
DIFYNNSFKNGLLPIRIDQDIILSKLYPVATSGKKLTIDLPNQQILGPDKEVLVEHFEVE
DFRKHCLINGLDDIGITLQKEEFINKYEEMRRDRFSFLEGGSKLIVPARGTKRSRYGNKA
QEW
NT seq
2352 nt
NT seq
+upstream
nt +downstream
nt
atgccttccactggagagataaaaaatccaaagaccttatacgacaaggtctttgaagat
catgttgttcacaaagatgaatcaggctcttatttattatacatcgaccgtcatttggtc
cacgaagttacttccccacaagccttcgaaggtcttaagaatgctggtagagtagtcaga
aggaaagattgcacacttgctacagtagatcacaacattccaacggattctagaaaaaac
ttaactaccttggacaagttcattaagcaggatgactccagattacaggtgaagacatta
gagcaaaacgtcaaggactttgatgtcacctattttggtatgaaagatagccgtcaaggt
attgtccacgttgtaggacctgagcaagggttcaccttgccaggtactacggttgtgtgt
ggtgactcccatacttccacgcatggtgccttcggttctctagcttttggtattggaact
tctgaagttgagcatgttctggcaactcaaacaattattcaagcaaaatcaaagaacatg
agaataaccatcgagggcgagctggacgaaggtatcacctctaaggatttagttttacat
gttattggagtgattggtaccgcaggtggtactggtagtgtcattgaattcgctggtaag
gcaattgaagatctaactatggaagcaagaatgtctatttgtaatatggcaattgaagcc
ggtgccagagctggtatgatcagaccagatgagactactttcaagtatatcgagggacgc
cccctggctccaaaaggagagcaatggaccaaggctctaaactattggaagactttatat
tctgatgaaggtgctaaatttgactatgaaatcgtgatcaaggccaaagatattgttcct
actatcacttggggtacatctcctcaagacgctctgccaattaccgcatctgtgccagac
ccagagaaggttgaagatcctatcaagaagtcgggaatggaaagagctttatcttacatg
ggattaacacctaatgtcccactaaaggatatcaagattgataaggttttcattggatct
tgtaccaactctcgtttggaggatctgcgagctgctgccaaagtggtaaaaggtcacaag
aaatccgacaatgttaaactagctctggttgttccagggtctggtttgatcaaactacaa
gctgaaaaggagggtttggacaagatatttgaagaggctgggttttcctggagagaggcc
ggatgctctatgtgtctgggaatgaatcctgatattctggacccagaagagagatgcgcc
tccacttcaaacagaaactttgaaggtcgtcaaggtgctagatctagaacacatttgatg
tctcctgccatggcagcagcagctggtatagctggtcattttgttgacatcagagagttt
gaatacaaggaagacaagagtcaacccaagattgcaattcaaagtgaagaggatgctgaa
ttacaggacgctgtttacgagcatgaaaagaagcctctggctgagggtgaatctaaggat
gaactagaagaagatgaaattaaggacatacctccacctgatcacaccgttcaagaaact
cccctaaaaacttcagctccagctgttgcagctgcaatggaaaagtttttaactgttgag
ggtatcgctgctccattagataaggccaacgtcgacacggatgcaattattccaaagcaa
ttcttaaagactatcaaacgtacaggattaaaagctggtttgttctatgaattacgtttt
gtgaaggatgaccagggtaaagacgttgaaactgactttgttttaaatgtagagccttat
agatctgctagcatcctttgtgttaccggagacaactttggatgtggttcttctcgagaa
cacgctccttgggccctgaaagattttggtataagatctatcattgctccatcatttggt
gatattttctacaacaattccttcaagaacggattactccctatcagaattgatcaagat
attattttatctaagctataccctgttgctacaagcggaaagaaacttaccatagatctt
ccaaaccaacagattttaggccccgataaggaagttcttgtagaacatttcgaagtcgaa
gatttcagaaagcactgcttaatcaatggtctggatgatattggaatcactctccaaaaa
gaggagttcatcaacaagtacgaagagatgagaagagatagattctctttccttgaagga
ggatccaaactaatcgtcccagccagaggtaccaagagaagccgttacggaaataaagct
caagaatggtaa
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