Panthera pardus (leopard): 109249879
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Entry
109249879 CDS
T06062
Symbol
MAP3K5
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 5 isoform X1
KO
K04426
mitogen-activated protein kinase kinase kinase 5 [EC:
2.7.11.25
]
Organism
ppad
Panthera pardus (leopard)
Pathway
ppad01524
Platinum drug resistance
ppad04010
MAPK signaling pathway
ppad04071
Sphingolipid signaling pathway
ppad04141
Protein processing in endoplasmic reticulum
ppad04210
Apoptosis
ppad04530
Tight junction
ppad04668
TNF signaling pathway
ppad04714
Thermogenesis
ppad04722
Neurotrophin signaling pathway
ppad04932
Non-alcoholic fatty liver disease
ppad04936
Alcoholic liver disease
ppad05010
Alzheimer disease
ppad05012
Parkinson disease
ppad05014
Amyotrophic lateral sclerosis
ppad05016
Huntington disease
ppad05017
Spinocerebellar ataxia
ppad05022
Pathways of neurodegeneration - multiple diseases
ppad05208
Chemical carcinogenesis - reactive oxygen species
ppad05417
Lipid and atherosclerosis
ppad05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ppad00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
109249879 (MAP3K5)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
109249879 (MAP3K5)
04668 TNF signaling pathway
109249879 (MAP3K5)
04071 Sphingolipid signaling pathway
109249879 (MAP3K5)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
109249879 (MAP3K5)
09144 Cellular community - eukaryotes
04530 Tight junction
109249879 (MAP3K5)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
109249879 (MAP3K5)
09159 Environmental adaptation
04714 Thermogenesis
109249879 (MAP3K5)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
109249879 (MAP3K5)
09164 Neurodegenerative disease
05010 Alzheimer disease
109249879 (MAP3K5)
05012 Parkinson disease
109249879 (MAP3K5)
05014 Amyotrophic lateral sclerosis
109249879 (MAP3K5)
05016 Huntington disease
109249879 (MAP3K5)
05017 Spinocerebellar ataxia
109249879 (MAP3K5)
05022 Pathways of neurodegeneration - multiple diseases
109249879 (MAP3K5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
109249879 (MAP3K5)
05418 Fluid shear stress and atherosclerosis
109249879 (MAP3K5)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
109249879 (MAP3K5)
04932 Non-alcoholic fatty liver disease
109249879 (MAP3K5)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
109249879 (MAP3K5)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ppad01001
]
109249879 (MAP3K5)
Enzymes [BR:
ppad01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
109249879 (MAP3K5)
Protein kinases [BR:
ppad01001
]
Serine/threonine kinases: STE group
STE11 family
109249879 (MAP3K5)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
MAP3K_TRAF_bd
Pkinase
HisK-N-like
PK_Tyr_Ser-Thr
ASK_PH
TPR-S
DRHyd-ASK
Kinase-like
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
109249879
NCBI-ProteinID:
XP_019276019
Ensembl:
ENSPPRG00000001889
UniProt:
A0A9V1E843
LinkDB
All DBs
Position
Unknown
AA seq
1367 aa
AA seq
DB search
MSAEAGEGITFSVPPLAEGGSCRRGAAAAAAEGEESQLPPPPPGSFWNVESAAAPGTGCP
AATSGSSATRCRGNSGGGGGRRTTVAYVINEASQGQLVMAESEALQSLREACETVGATLE
TVHFGKLDFGETAVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYCDNN
SDSLQSLKEIICQKNTMCTGNYTFVPYMITPHNKVYCCDSSFMKGLTELMQPNFELLLGP
ICLPLVDRFIQLLKVAQASSSQYFRESILNDIRKARNLYTGKELAAELARIRQRVDNIEV
LTADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFDLASHHHVKFHYAFALNRRNLPGDR
AKALDIMIPLVQSEGQVASDMYCLVGRIYKDMFLDSNFLDTESRDYGASWFKKAFESEPS
LQSGINYAVLLLAAGHQFESSFELRKVGVKLSSLLGKKGNLEKLQSYWEVGFFLGASVLA
NDHMRVIQASEKLFKLKTPAWYLKSIVETILIYKHFVKLTTEQPVAKQELVDFWMDFLVE
ATKTDVTVVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVLPDDKKGIHEWNFSASS
VRGVSISKFEERCCFLYVLHNSDDFQIYFCTELHCKKFFEMVNTITEEKGRSTEEGDCEG
DSLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIAL
HKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQIL
EGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAP
EIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMS
AEAKAFILKCFEPDPDKRACANDLLIDEFLKVSSKKKKTQPKLSALSAGSNAEYLRSISL
PVPVLVEDTSSSSEYGSVSPDTELKVDPFSFKTRAKSCGERDVKGIRTLFLGIPDENFED
HSAPPSPEEKDSGFFMLRKDSERRATLHRILTEDQDKVVRNLMESLAQGTEEPKLKWEHI
TTLIASLREFVRSTDRKIIATTLSKLKLELDFDSHGISQVQVVLFGFQDAVNKVLRNHNI
KPHWMFALDSIIRKAVQTAITILVPELRPHFSLASESDTADQEDLDAEDEREEQPSNQTV
QRPHAVIEDAVATSGVSTLSSTVSHDSQNAHRSLNVQLGRMKIETNRLLEELVQKEKELQ
ALLHQAIEEKDHEIKHLKLKSQPIDIPGVPVCHRDSLGTNAEESELAEWLREKGADEDTI
SRFLAEDYSLEDVLYYVTRDDLKCLRLRGGILCTLWKAITDFRDKQT
NT seq
4104 nt
NT seq
+upstream
nt +downstream
nt
atgagcgcggaggcgggcgagggcatcactttctccgtgccacccttggccgagggcggc
agctgccggaggggagcagcggcggcggcggccgagggcgaggagagccagctaccaccg
ccgccgccgggcagcttctggaacgtggagagtgccgccgccccgggcaccgggtgtccc
gctgccacctctgggagcagcgccacccggtgccggggcaactctggtggcggaggcggc
cgacggaccacggtggcgtatgtgatcaacgaagcgagccaggggcagctggtgatggcc
gagagcgaggccctgcagagcctgcgggaggcgtgcgagacggtgggcgccaccctggag
accgtgcattttggtaaactggactttggggaaaccgcggtgctggatcgtttctacaat
gcagatatcgctgtggtggagatgagtgacgccttccgacagccatcgttgttttaccac
ctcggggtcagagaaagtttcagcatggccaacaacatcatcctctactgtgataataat
tcagactctctgcagtcactgaaggaaatcatttgccagaagaatactatgtgcactggg
aactacacattcgttccttacatgatcactccgcataataaagtctactgctgcgatagc
agcttcatgaaggggttgacagagctcatgcaaccgaacttcgagctgcttcttggaccc
atttgcttacctcttgtggaccgtttcattcaacttctgaaggtggcacaagcaagttcc
agccagtatttccgggaatctatactcaatgatatcaggaaagctcgtaatttatacact
ggtaaagaattggcagctgaattggcaagaattcggcagcgagtagataatattgaagtc
ttgacagcagatattgtcataaacctgttactttcctacagagatatccaggactatgat
tctattgtgaagctggtagagacgttagaaaagctgccaacctttgatttggcttcccat
caccatgtgaagtttcattatgcatttgcactgaataggagaaatctccctggagacaga
gcaaaagctcttgatattatgattcccctggtgcaaagtgaagggcaagttgcttcagat
atgtattgcctagtgggccgaatctacaaagatatgtttttggactctaatttcctggac
actgaaagtagagactatggagcttcttggttcaaaaaggcatttgaatctgagccatca
ctacagtcaggaattaattatgcggtccttctcctggcagctgggcaccagtttgaatct
tcctttgagctccggaaagttggggtgaagctaagtagccttcttggtaaaaagggaaac
ttagaaaaactccagagctactgggaagttggattttttctgggtgccagtgtcctggcc
aatgaccacatgagagtcatccaagcatctgaaaagctttttaaactgaagacgccagca
tggtacctcaagtctattgtagagacaattttgatatataagcattttgtgaaactgact
acagagcagcctgtggccaaacaggagctggtggacttctggatggatttcctggtggag
gccacaaagacagatgttactgtagttaggtttccggtgttaatattagaaccaactaaa
atctatcagccttcatatttgtctatcaacaatgaagttgaggaaaagacaatatctatt
tggcatgtgcttcctgatgacaagaaaggtatacatgagtggaattttagtgcttcttct
gtcaggggagtgagtatttctaaatttgaagaacgatgctgttttctttatgtgcttcat
aattctgacgatttccaaatctatttctgtacagaacttcattgtaaaaagttttttgaa
atggtgaacaccattaccgaagagaaggggagaagcacagaggaaggtgattgtgaaggt
gactccttggagtatgactacgaatatgatgagaacggagacagagttgttttaggcaag
ggcacttacgggattgtctacgcaggccgagacctgagcaaccaagtcagaattgctata
aaggaaatcccagaaagagatagcagatactcccagcccctacatgaagaaatagcattg
cataagcatctgaagcataaaaatattgtccagtatctgggctctttcagtgagaatggt
ttcatcaaaatcttcatggagcaggtcccaggaggaagtctttcagctctccttcgttcc
aaatggggcccattgaaggacaatgagcaaacaattggcttctatacaaagcaaatactt
gaaggattaaaatacctccatgacaatcagatagtccaccgggatataaagggtgacaat
gtgttgattaatacctacagtggcgttctcaagatctcagacttcgggacatcaaagagg
cttgctggcattaacccgtgtactgaaacttttactggtacccttcagtatatggcacca
gaaatcatagacaaaggaccaagaggctacgggaaagcagcagacatttggtctttgggc
tgcacgatcatcgaaatggccacagggaaaccacctttttatgaactgggagaaccacaa
gcagctatgttcaaggtgggaatgtttaaagtccacccggagatcccagagtccatgtcc
gcagaggccaaggcgttcatattgaaatgttttgaaccggaccccgacaagagagcctgt
gctaacgacttgcttattgacgagttcttaaaagtttcaagcaaaaagaagaagacgcaa
cctaagctttcagccctctcagctggatcaaatgcagagtaccttagaagcatatccttg
cccgtgcccgtcttggtggaggacaccagcagcagcagcgaatacggctcggtttctccg
gacacggagttgaaggtggatcccttctctttcaagacgagagccaaatcctgtggagag
cgagacgtaaaaggaatacggacactctttctgggcattccagacgaaaatttcgaagac
cacagcgctccaccttcccctgaagagaaagattctggattctttatgctgaggaaggac
agtgagagacgggccactcttcacaggatcctgaccgaagaccaagacaaagttgtgagg
aacttaatggaatctttggctcaggggactgaagaacctaaactaaaatgggaacacatc
acaaccctcattgcaagcctcagagaatttgtgagatccacggaccgaaaaatcatagcc
accacactgtctaagctgaagctagaacttgactttgacagccatggcatcagtcaagtt
caggtggtactcttcggttttcaagatgccgtcaataaagttcttcggaatcataacatc
aagccacactggatgtttgccttagacagtatcatccgaaaggcggtgcagacggccatc
accattctggtgccagaactgaggccacatttcagcctcgcatctgagagtgataccgcg
gatcaagaagacttggatgcggaagatgagcgtgaggaacagccttcaaaccaaactgtc
caaagacctcatgctgtcattgaagatgccgtggctacctcaggggtgagcacgctcagt
tctactgtatcccatgactcccaaaatgctcaccgatcactcaatgtgcagcttggaagg
atgaaaatagaaactaatagattactggaagaattggttcagaaagagaaagaattacaa
gcactccttcatcaagctattgaagaaaaagaccacgaaattaaacacctgaagcttaag
tcccaaccaatagatattcctggagtgcctgtgtgtcaccgggattctctgggcacaaat
gctgaagagtctgaacttgctgaatggctgagagaaaagggagctgatgaagacactata
agtcggtttctggctgaggattattcactagaggatgttctctactatgttacacgtgat
gatttaaaatgcctgagactaaggggaggaatactctgcacgctgtggaaggccatcact
gactttcgagacaaacagacttga
DBGET
integrated database retrieval system
