Panthera pardus (leopard): 109260360
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Entry
109260360 CDS
T06062
Symbol
ATR
Name
(RefSeq) serine/threonine-protein kinase ATR
KO
K06640
serine/threonine-protein kinase ATR [EC:
2.7.11.1
]
Organism
ppad
Panthera pardus (leopard)
Pathway
ppad03460
Fanconi anemia pathway
ppad04110
Cell cycle
ppad04115
p53 signaling pathway
ppad04218
Cellular senescence
ppad05165
Human papillomavirus infection
ppad05166
Human T-cell leukemia virus 1 infection
ppad05170
Human immunodeficiency virus 1 infection
Brite
KEGG Orthology (KO) [BR:
ppad00001
]
09120 Genetic Information Processing
09124 Replication and repair
03460 Fanconi anemia pathway
109260360 (ATR)
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
109260360 (ATR)
04115 p53 signaling pathway
109260360 (ATR)
04218 Cellular senescence
109260360 (ATR)
09160 Human Diseases
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
109260360 (ATR)
05170 Human immunodeficiency virus 1 infection
109260360 (ATR)
05165 Human papillomavirus infection
109260360 (ATR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ppad01001
]
109260360 (ATR)
09182 Protein families: genetic information processing
03400 DNA repair and recombination proteins [BR:
ppad03400
]
109260360 (ATR)
Enzymes [BR:
ppad01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
109260360 (ATR)
Protein kinases [BR:
ppad01001
]
Serine/threonine kinases: Other
PIKK family [OT]
109260360 (ATR)
DNA repair and recombination proteins [BR:
ppad03400
]
Eukaryotic type
Check point factors
Other check point factors
109260360 (ATR)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI3_PI4_kinase
FAT
UME
FATC
HEAT
Mad3_BUB1_I
HBB
THP2
Motif
Other DBs
NCBI-GeneID:
109260360
NCBI-ProteinID:
XP_019294079
Ensembl:
ENSPPRG00000003180
LinkDB
All DBs
Position
Unknown
AA seq
2643 aa
AA seq
DB search
MGDHGLELASMIPALRELGSASPEEYNTVVQKPRQILCQFIDRILTDVNVVALELVKKTD
SQPTSVMLLDFIQHIMKSSPLMFVNVNGSQGQNEVKDSIEFSNWIITRLLRIAATPSCHT
LHKKICEVICSLLFLFKSKSPAIFGVLTKELLHLFEDVICLHKRNAVGHFVEWPVVVSRF
LSQLDERVGYLQPAPLQFMNMQNLEFIEVTLLTVLIRIIAIVFFRRQELLLWQIGCMLLE
YGSPKIKSLAISLLTELFELGGLPAQPASTFFRSFLELLKHLVEMDADQLKLCEEPLSKL
IKTLFPFEAEAYRNIEPVYLNMLLEKLCVMFEDGVLMQLKSDLLKAALCHLLQYFLKYVP
AGYESALQVRKVYVRNICKVLVDVLGFQVDAEYLLGPLYAALKMESMEIIEEVQCQIQQE
NLSSNSDVISSKRRRLSSSLNSSKRPPKQTEEIKHVDMNKKSILWSTLKQKAESLQISLE
CGSLKNPVIETLEGITVILQLTALCTVHCSHQNMDCHNFKDCQQKCKKKPSVVVTWMSLD
FYTKALKSCRSLLESVQKPDLEVVIDKVVKIYDALIYIHVKTSFEDHILEDLCGMLSLPW
IHSHSDDGSLKLTTFATNLLALSQRISDSCSPQAQSRCVFLLTLFPRRIFLEWRTAVYSW
ALQSSHEVIRASCVNGFFILLQQQNSCNRVPKILIDKVKDDSDFVKKEFASILGQLVCTL
HGMFHLTNSLTEPFSEHGHIDLFCKSLKVTSQHECSSSQLKASVCKPFLFLLKKKTPSPV
KLAFIDNLYHLCKHLDFREDETDVKTVLGTLLNLMEDPDKDVRVAFSGNIKHILESLDSE
DGFIKELFVLRMKEAYTHAQISRNNELKDTLILTTGDIGRAAKGDLVPFALLHLLHCLLS
KSASVSGAAYTEIRALVAAKSVKLQNFFSQYKKPICQFLVESLHSSQMTALPSTPCQNAE
MRKQDVAHQREMALNTLSEIANVFDFPDLNRFLTRTLQVLLPDLAAKASPAASALIRTLG
KQLNVNRREILINNFKYIFSHLVCSCSKDELERALHYLKNETEIELGSLLRQDFQGLHNE
LLLRIGEHYQQVFNGLSILASFASSDDPYQGPREIASPELMADYLQPKLLGILAFFNMQL
LSSSVGIEDKKMALNSLMSLMKLMGPKHVSSVRVKMMTTLRTGLRFKDDFPELCCRAWDC
FVRCLDHAYLGSLLSHVIVALLPLIHIQPKETAAIFHYLIIENRDAVQDFLHEIYFLPDH
PELKKIKAVLQEYRKETSESTDLQTTLQLSMRAIQHENVDVRIHALTSLKETLYKNQEKL
IKYATDSETVEPVISQLVTVLLKGCQDANSQARLLCGECLGELGAVDPGRLDFSTTESQG
KDFTFVTGVEDSNFAYGLLMELTRAYLAYADNSRAQDSAAYAIQELLSIYDCREMQTDGP
GHQLWRRFPEHVREILEPHLNTRYKSSQKSTDWSGVKKPIYLSKLGNNFAEWSASWAGYL
ITKVRHDLASKIFTCCSIMMKHDFKVTIYLLPHILVYVLLGCNQEDQQEVYAEIMAVLKH
DDQHTINTQDSASDLCQLSTQTVFSMLDHLTQWARHKFQALNAEKFPQSKSNRDKVDSIV
STADYEDYQSVTRFLDLIPQDTLAVASFRSKAYTRAVMHFESFITEKKQNIQEHLGFLQK
LYAAMHEPDGVAGVSAIRKAEPSLKEQILEHESIGLLRDATACYDRAIQLEPDQIIHYHG
VVKSMLGLGQLSTVITQVNGVHANRSEWTDELNTYRVEAAWKLSQWDLVENYLAADGKST
TWSVRLGQLLLSAKKRDVTAFYDTLKLVRAEQIVPLSAASFERGSYQRGYEYIVRLHMLC
ELEHSIKPLFQQSPGDTSQEDSLNWVARLEMTQNSYRAKEPILALRRALLSLNKRPDYNE
MVGGCWLQSARVARKAGHHQTAYNALLNAGESRLAELYVERAKWLWSKGDVHQALIVLQK
GVELCFPENKTPTESKNMLIHGRAMLLVGRFMEETANFESNAVMKKYKDVTLFLPEWEDG
HFYLAKYYDKLMPMVTDNKMEKQGDLIRYIVLHFGRSLQYGNQFIYQSMPRMLSLWLDFG
AKAYEWEKAGRSDRVQMRNDLAKINKVITEHTNHLAPYQFLTAFSQLISRICHSHDEVFV
VLMEIIAKVFLAYPQQAMWMMTAVSKSSYPMRVNRCKEILNKAIHMKKSLEKFVGDATRL
TDKLLELCNKPVDGSSSTLSMSTHFKMLKKLVEEPTFSEILIPLQSVMIPTLPSIPGAHA
NHEPFPGHWAYIASFDDTVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEF
NSLINKCLRKDAESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKEKGVYM
TGKELRQCMLPKAAALSEKLKVFQEFLLPRHPPVFHEWFLRTFPDPTSWYSSRSAYCRST
AVMSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKGETFEVPEIVPFRLTHNMVN
GMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEWSKPVKGHSKAPLNETG
EVVNEKAKTHVLDIEQRLQGVIKTRNRVTGLPLSIEGHVHYLIQEATDENLLCQMYLGWT
PYM
NT seq
7932 nt
NT seq
+upstream
nt +downstream
nt
atgggcgaccacggcctggagctggcgtctatgatccccgcgctgcgggagttgggaagt
gccagtccagaggaatataatacagttgtacagaagccaagacaaattctatgtcagttc
attgaccgaatacttacagatgtaaacgttgttgctctagaacttgtaaagaaaactgac
tcccagccaacctctgtgatgttgcttgatttcatccagcatataatgaagtcctcccca
cttatgtttgtaaatgtgaatggaagccaagggcaaaatgaggtcaaagacagtattgaa
ttcagtaattggatcataacaagacttctgcggattgcagcaactccatcctgtcatacg
ttacacaagaaaatctgtgaagttatctgctcattattatttctttttaaaagcaagagt
cctgcaatttttggagtactaacaaaggaattactgcatctttttgaagatgtgatttgc
ctccataaaagaaatgcagtgggacactttgtggaatggccagtggtagttagccgattt
ttaagtcaattagatgaacgtgtgggatatttacaaccagctcctttgcaattcatgaac
atgcaaaatttagaatttattgaagtcaccttattaacagttcttattcgtattattgca
attgtgttttttagaaggcaagaactcttactttggcagataggttgtatgctgctagag
tatggtagtccaaaaattaaatccttagcaattagccttttaactgaactctttgagctt
ggaggattaccagcacaaccagccagcacttttttccggtcatttttggaattattaaaa
catcttgtagaaatggatgctgaccagttgaaactctgtgaagagccattatcaaagctg
ataaaaacactatttccctttgaagcagaagcttatagaaatattgaacctgtctattta
aatatgctgctggaaaaactctgtgtcatgtttgaagatggtgtccttatgcagcttaag
tctgatttgctaaaagcagctttgtgccacttactgcagtatttccttaaatatgtgcca
gctgggtatgaatctgctctacaagtcaggaaggtttatgtgagaaacatttgtaaagtt
cttgtggatgtgcttggatttcaggtagatgcagagtatttgttgggcccactttatgcc
gccttaaaaatggaaagtatggaaatcattgaggaggttcagtgccaaattcaacaggaa
aacctcagcagtaatagtgatgtaatatcatccaaaagacgtcgactcagctcatctcta
aactcttccaaaagaccaccaaaacagactgaggaaattaaacatgtggatatgaacaaa
aagagcatattatggagtacactgaaacagaaagctgaatcccttcagatttcccttgaa
tgtggtagtctaaagaatcctgttatcgagactttagaaggaatcacggttatcctacaa
ctgactgctctgtgtactgttcattgttctcatcaaaacatggactgccataatttcaag
gactgtcaacagaaatgtaagaagaaaccttcagtagtggtaacttggatgtctttggat
ttttacacaaaagcgcttaagagctgtaggagtttgttggaatctgttcagaaacctgac
ctggaggtagttattgataaagtggtgaaaatatatgatgctctaatttatattcacgta
aaaacttcatttgaagatcatatactggaagatttatgtggaatgctttcacttccatgg
attcattcccattctgatgatggctctttaaagttgactacatttgctactaatcttcta
gcgttaagccagaggatttctgatagctgctcaccacaggcacagtcacggtgtgtgttt
cttctaactttatttccaagaagaatattccttgaatggagaacagcagtttatagctgg
gccctacagagctcccatgaagtaatccgggctagttgtgttaatggattttttatcttg
ttgcagcagcagaattcttgtaacagagttcccaagattcttatagataaagtcaaagat
gattccgactttgtcaagaaagaatttgcctctattcttggtcaacttgtctgtacgctt
catggcatgtttcatttgacaaattctttaacagaacctttctctgaacatggacatatt
gacctattctgtaagagcctaaaagtcacttctcaacatgaatgttcatcttctcaacta
aaagcttctgtttgcaagccattcctttttctactgaaaaaaaaaacacctagtccagtg
aaacttgctttcatagataatttatatcatctttgtaagcaccttgattttagagaagat
gaaacagatgtaaaaacagttcttggaactttattaaatttaatggaagatccagacaag
gatgttagagtggcttttagtggaaatatcaagcatatattggaatccttggactctgaa
gatggatttataaaagagctttttgtcttaagaatgaaggaagcatatacacatgctcaa
atctcaagaaataatgagttgaaggataccttgattcttacaacaggggatattggaagg
gcagcaaaaggagatttggtaccttttgcccttttgcacttattgcattgtttattatcc
aagtcagcatctgtctctggagcagcatacacagaaatcagagctctggttgcagctaag
agtgttaaactgcagaactttttcagccagtataagaaacccatctgtcagtttttagta
gaatctctccactccagtcagatgacagcacttcctagtactccatgccagaatgctgag
atgcggaaacaagatgtggctcaccagagagaaatggctttaaataccttgtctgaaatt
gccaatgtttttgactttcctgatcttaatcgtttccttactaggacattacaagttctg
ctccctgaccttgctgccaaagcaagccctgcagcctctgctctcattcgaactttagga
aaacagttaaatgtcaatcgtagagaaattttaataaataacttcaaatatattttttct
catttggtctgttcctgttccaaggatgaattagaacgtgcccttcattatctgaagaat
gaaacagaaattgaattgggaagcctattgagacaagatttccaaggactgcataatgaa
ttattgctacgtattggagaacactatcaacaggttttcaatggtttgtcaatacttgca
tcatttgcatctagtgatgatccatatcagggccccagagagatcgcatctcccgaatta
atggctgattacttgcaacctaagttgttgggaattttggccttttttaacatgcagtta
ctgagctccagtgttggcattgaagataagaaaatggctctgaatagtttgatgtctttg
atgaagttgatgggaccaaaacatgtcagttctgtgagggtgaagatgatgaccacgcta
agaactggcctgagattcaaggatgattttcctgaattgtgttgcagagcttgggattgc
tttgttcgttgcctggaccatgcttatcttggttcccttctcagtcatgtgatagtagct
ttgttgcctctcatacacatccagcctaaagaaactgcagctatatttcactacctcata
attgaaaacagggatgctgtgcaagattttcttcatgaaatatattttttacctgatcat
ccagaattaaaaaagataaaagcagttctacaggaatacagaaaggagacctctgagagt
actgatcttcagacaactcttcaactatccatgagagcaattcaacatgaaaatgtagat
gttcgtattcatgctcttacaagcttgaaggaaactttgtataaaaatcaggaaaaactg
ataaaatatgcaacagatagtgaaacagtggaacctgttatctcccagctggtaacggtg
cttttgaaaggttgccaggatgcaaactctcaagctcggttgctctgtggggaatgttta
ggggaattgggggcagtagatccaggtcgactagatttctcaacaactgaaagccaagga
aaagattttacatttgtgactggagtagaagattcaaactttgcctatggattattgatg
gaacttacaagagcttaccttgcatatgccgataacagtcgggctcaagattcagctgct
tatgccattcaggagttactttctatttatgactgcagagagatgcagactgatggccca
ggtcaccagttgtggaggagatttcctgagcatgttcgggaaatcctggaacctcatcta
aatactagatataagagttctcagaagtcaacagattggtctggagtaaagaagccaatt
tacttaagtaaattaggtaataactttgcagaatggtcagcatcttgggcaggttatctt
ataacaaaggttcggcatgatcttgccagtaaaatcttcacctgctgtagcattatgatg
aaacacgatttcaaagtgactatctatcttcttccacatattctagtgtatgtcttgttg
ggttgtaatcaagaagatcagcaggaggtttatgcagaaattatggcagttctaaagcat
gatgatcagcataccataaatacccaagacagtgcatctgatctgtgtcaactcagtaca
cagactgtgttctccatgcttgaccatctcacacaatgggcaagacacaaatttcaggca
ctgaatgcagagaaatttccacaaagcaaatcaaacagagataaggtagactcaatagta
tctactgcggattatgaagactatcagagtgtaactcgttttctagacctcatacctcag
gatactctggcagtagcttcctttcgctccaaagcatatacacgagctgtaatgcacttt
gaatcatttattacagaaaagaaacaaaatattcaggagcatcttggatttttacagaaa
ttgtatgctgctatgcatgaacctgatggggtggctggagtaagcgcaattcgaaaggca
gaaccatctctgaaagaacagatccttgaacatgaaagcattggcttactgagggatgcc
actgcttgttatgacagagctattcagctagaaccagaccagattattcattatcatggt
gtagtgaagtccatgttaggtcttggacagctgtctactgtaatcactcaggtgaatgga
gtgcatgctaacaggtctgaatggacagatgaattaaacacatacagagtggaagcagct
tggaaattgtcacagtgggatttggtggaaaactatttggcagcagatgggaaatctaca
acatggagtgtcagactgggacagctattattatcagccaaaaaaagagatgtcacagct
ttttatgacacactgaaactagtgagagcagaacaaattgtacctctttcagctgcaagc
tttgaaagaggctcttatcaacgaggatatgaatatattgtgagattgcacatgttgtgt
gaattggagcatagcatcaaaccactttttcaacagtctccaggtgatacctctcaagaa
gattctctaaactgggtagctcgactagaaatgacccagaattcctacagagccaaggag
cccatcctggctctccggagagctttgttaagcctcaacaaaagaccagattataatgaa
atggttggaggatgctggctacagagtgccagagtagctaggaaggctggtcaccaccaa
acagcctacaatgctctcctaaatgctggagaatcacgacttgctgaactgtatgtggaa
agagcaaagtggctatggtccaagggtgatgttcaccaggcactaattgttcttcagaag
ggtgttgaattatgttttcctgaaaataaaaccccaaccgagagtaagaacatgttaatc
catggtcgagctatgctgctagtgggccgatttatggaagaaacagctaactttgaaagc
aatgcagttatgaaaaaatataaggatgtgaccttgttcctgccagagtgggaagatggg
catttttatcttgccaagtactatgacaaattgatgcccatggtcacagataacaagatg
gaaaagcagggtgatctcattcggtatatagttcttcattttggcagatctctacaatat
gggaaccaattcatatatcagtcaatgccacgaatgttatcactatggcttgattttggt
gctaaggcatatgaatgggaaaaagctggccgttctgatcgtgtacaaatgagaaatgat
ttagctaaaataaacaaggttattacagagcacacaaatcacttagcaccgtatcagttt
ttgactgctttttcacagttgatctcccgaatttgtcattctcacgatgaagtttttgtt
gtcttgatggaaattatagccaaagtgtttctggcctatcctcaacaagcaatgtggatg
atgacagctgtgtcaaagtcttcttatcccatgcgtgtgaacagatgcaaggaaatccta
aataaagctattcatatgaaaaaatccttagaaaagtttgttggagatgcaactcgccta
acagataagcttctagaattgtgcaataaaccggtggatggaagtagttctacattaagt
atgagcactcattttaaaatgcttaaaaagctggtagaagaaccaacatttagtgaaatc
ctcattcctttacagtcagtcatgatacctactcttccatcaattccgggtgctcatgcc
aaccacgagccatttcctgggcattgggcctatattgccagctttgatgatacggtggaa
attcttgcatcccttcagaaaccaaagaagatctctttaaaaggatcagatggaaagttc
tacatcatgatgtgtaagcctaaagatgacctgagaaaggattgtagactgatggaattt
aattccttgattaataagtgcttgagaaaagatgcagaatctcgcagaagagaacttcat
atccgaacatacgcagttattcccctgaatgatgaatgtgggattattgaatgggttaac
aacactgctggcttgagacctattctgaccaaactatataaggaaaagggagtttatatg
acaggaaaagaacttcgccagtgtatgctaccaaaagccgcagctttgtctgaaaaactc
aaagtattccaagaatttctcctacccaggcatcctcctgtttttcatgagtggtttctg
aggacattccctgatcctacatcatggtacagtagcaggtcagcatactgtcgttccact
gcagttatgtcaatggttggttatatcctggggcttggagaccgtcatggtgaaaacatc
ctctttgattctttgactggtgaatgtgtacatgtggatttcaactgtctcttcaataag
ggggaaacctttgaagttccagaaattgttccatttcggctgactcataatatggttaat
ggaatgggtcctatgggaacagaaggtctttttcgaagagcttgtgaagttacaatgagg
ctgatgcgagatcaaagagagcctttaatgagtgtcttaaaaacttttctacacgatcct
ctggtggaatggagtaaaccagtgaaaggacattccaaagcaccactgaatgaaaccggg
gaagttgtcaatgaaaaggccaagacccatgttcttgacatcgagcagcgactgcaaggt
gtaatcaagacccgaaatagagtgacagggctgccgttatctattgaaggacatgtgcat
taccttatacaagaagctactgatgaaaacttactatgccagatgtaccttggttggact
ccatatatgtga
DBGET
integrated database retrieval system
