Panthera pardus (leopard): 109275622
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Entry
109275622 CDS
T06062
Symbol
PDHA2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
ppad
Panthera pardus (leopard)
Pathway
ppad00010
Glycolysis / Gluconeogenesis
ppad00020
Citrate cycle (TCA cycle)
ppad00620
Pyruvate metabolism
ppad00785
Lipoic acid metabolism
ppad01100
Metabolic pathways
ppad01200
Carbon metabolism
ppad01210
2-Oxocarboxylic acid metabolism
ppad04066
HIF-1 signaling pathway
ppad04922
Glucagon signaling pathway
ppad05230
Central carbon metabolism in cancer
ppad05415
Diabetic cardiomyopathy
Module
ppad_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ppad00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
109275622 (PDHA2)
00020 Citrate cycle (TCA cycle)
109275622 (PDHA2)
00620 Pyruvate metabolism
109275622 (PDHA2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
109275622 (PDHA2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
109275622 (PDHA2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
109275622 (PDHA2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
109275622 (PDHA2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
109275622 (PDHA2)
Enzymes [BR:
ppad01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
109275622 (PDHA2)
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Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
109275622
NCBI-ProteinID:
XP_019319378
Ensembl:
ENSPPRG00000014814
UniProt:
A0A9V1GC59
LinkDB
All DBs
Position
Unknown
AA seq
391 aa
AA seq
DB search
MRKMLAAAVSRVLSGVTQKPTSRVLVASCNYSNDAMFAIKKCDLYRLEEGPPVTTVLTRE
DGLKYYRMMQTVRRMELKADQLYKQKFIRGFCHLCDGQEACSVGLEAGINPTDHVITSYR
AHGLCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYVKNFYGGNGIVGAQGPLGAGIAL
ACKYKGNKEVCLTLYGDGAANQGQIAEAHNMAALWKLPCVFICENNLYGMGTPVERASAS
TDYYKRGNFIPGLRVDGMDVLGVREATKFVADYCRSGKGPIVMELQTYRYHGHSMSDPGI
SYRTREEVQNVRKKSDPIMLLKDRMVNSELATVEELKDIDVEVRKEVEDAAQFAMTDPEP
PLEELAHHIYCNTPAFEVRGANQWIKFKSLS
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgctgccgctgtctcccgcgtgttgtccggggtcacgcagaagccc
actagcagagtgctggtggcatcctgtaactattcaaatgatgcgatgtttgcaattaag
aaatgtgatctttatcgcttagaagagggtccccctgtcacaacagtgctcacccgggag
gatgggctcaaatactacaggatgatgcagactgttcgccgaatggagctgaaggcagat
cagctgtataaacaaaaatttatccgtgggttctgtcacttgtgcgatggtcaggaagct
tgttctgtgggcctggaggccgggataaatcccaccgaccatgtcatcacctcctatcgg
gctcatggcttgtgctatactcgtggactctctgtccgatcaattcttgcagagctgaca
ggacgaaggggaggctgtgctaaaggaaaaggaggatcaatgcatatgtatgtcaagaat
ttctatggaggcaatggcattgttggcgcacaggggcccctgggagctggtattgctctg
gcctgtaaatacaagggaaacaaggaggtctgtttgactctttatggggatggtgctgcg
aatcagggtcagatagctgaagctcacaatatggcagctttgtggaaattaccctgtgtt
ttcatctgtgagaataacctctatggaatgggaacccctgttgagagagcatcagccagc
accgattactataagagaggaaattttatccctggactaagggtagatggaatggatgtt
ctaggtgttcgggaggcaactaagtttgtagctgactactgtagatctggaaaggggccc
atagtgatggagctgcagacctaccggtatcatggacacagtatgagcgaccctgggatc
agttatcgtacccgagaagaagttcagaatgtgagaaagaagagcgatcctattatgctt
ctcaaagacagaatggtaaacagtgagcttgccactgttgaggaactaaaggatattgat
gttgaagtgaggaaagaagtggaggatgcagcccagtttgctatgactgatcctgaacca
cctttggaagaattagctcatcacatctactgcaatactccagcttttgaagttcgtggt
gcaaaccagtggattaagttcaagtccctcagttaa
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