Pteronotus mesoamericanus (Parnell's mustached bat): 129068919
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Entry
129068919 CDS
T09558
Symbol
EGFR
Name
(RefSeq) epidermal growth factor receptor isoform X1
KO
K04361
epidermal growth factor receptor [EC:
2.7.10.1
]
Organism
ppam
Pteronotus mesoamericanus (Parnell's mustached bat)
Pathway
ppam01521
EGFR tyrosine kinase inhibitor resistance
ppam01522
Endocrine resistance
ppam04010
MAPK signaling pathway
ppam04012
ErbB signaling pathway
ppam04014
Ras signaling pathway
ppam04015
Rap1 signaling pathway
ppam04020
Calcium signaling pathway
ppam04066
HIF-1 signaling pathway
ppam04068
FoxO signaling pathway
ppam04072
Phospholipase D signaling pathway
ppam04144
Endocytosis
ppam04151
PI3K-Akt signaling pathway
ppam04510
Focal adhesion
ppam04520
Adherens junction
ppam04540
Gap junction
ppam04630
JAK-STAT signaling pathway
ppam04810
Regulation of actin cytoskeleton
ppam04912
GnRH signaling pathway
ppam04915
Estrogen signaling pathway
ppam04921
Oxytocin signaling pathway
ppam04926
Relaxin signaling pathway
ppam04928
Parathyroid hormone synthesis, secretion and action
ppam04934
Cushing syndrome
ppam05160
Hepatitis C
ppam05163
Human cytomegalovirus infection
ppam05165
Human papillomavirus infection
ppam05171
Coronavirus disease - COVID-19
ppam05200
Pathways in cancer
ppam05205
Proteoglycans in cancer
ppam05206
MicroRNAs in cancer
ppam05207
Chemical carcinogenesis - receptor activation
ppam05208
Chemical carcinogenesis - reactive oxygen species
ppam05210
Colorectal cancer
ppam05212
Pancreatic cancer
ppam05213
Endometrial cancer
ppam05214
Glioma
ppam05215
Prostate cancer
ppam05218
Melanoma
ppam05219
Bladder cancer
ppam05223
Non-small cell lung cancer
ppam05224
Breast cancer
ppam05225
Hepatocellular carcinoma
ppam05226
Gastric cancer
ppam05230
Central carbon metabolism in cancer
ppam05231
Choline metabolism in cancer
ppam05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
ppam00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
129068919 (EGFR)
04012 ErbB signaling pathway
129068919 (EGFR)
04014 Ras signaling pathway
129068919 (EGFR)
04015 Rap1 signaling pathway
129068919 (EGFR)
04630 JAK-STAT signaling pathway
129068919 (EGFR)
04066 HIF-1 signaling pathway
129068919 (EGFR)
04068 FoxO signaling pathway
129068919 (EGFR)
04020 Calcium signaling pathway
129068919 (EGFR)
04072 Phospholipase D signaling pathway
129068919 (EGFR)
04151 PI3K-Akt signaling pathway
129068919 (EGFR)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
129068919 (EGFR)
09144 Cellular community - eukaryotes
04510 Focal adhesion
129068919 (EGFR)
04520 Adherens junction
129068919 (EGFR)
04540 Gap junction
129068919 (EGFR)
09142 Cell motility
04810 Regulation of actin cytoskeleton
129068919 (EGFR)
09150 Organismal Systems
09152 Endocrine system
04912 GnRH signaling pathway
129068919 (EGFR)
04915 Estrogen signaling pathway
129068919 (EGFR)
04921 Oxytocin signaling pathway
129068919 (EGFR)
04926 Relaxin signaling pathway
129068919 (EGFR)
04928 Parathyroid hormone synthesis, secretion and action
129068919 (EGFR)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
129068919 (EGFR)
05206 MicroRNAs in cancer
129068919 (EGFR)
05205 Proteoglycans in cancer
129068919 (EGFR)
05207 Chemical carcinogenesis - receptor activation
129068919 (EGFR)
05208 Chemical carcinogenesis - reactive oxygen species
129068919 (EGFR)
05230 Central carbon metabolism in cancer
129068919 (EGFR)
05231 Choline metabolism in cancer
129068919 (EGFR)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
129068919 (EGFR)
09162 Cancer: specific types
05210 Colorectal cancer
129068919 (EGFR)
05212 Pancreatic cancer
129068919 (EGFR)
05225 Hepatocellular carcinoma
129068919 (EGFR)
05226 Gastric cancer
129068919 (EGFR)
05214 Glioma
129068919 (EGFR)
05218 Melanoma
129068919 (EGFR)
05219 Bladder cancer
129068919 (EGFR)
05215 Prostate cancer
129068919 (EGFR)
05213 Endometrial cancer
129068919 (EGFR)
05224 Breast cancer
129068919 (EGFR)
05223 Non-small cell lung cancer
129068919 (EGFR)
09172 Infectious disease: viral
05160 Hepatitis C
129068919 (EGFR)
05171 Coronavirus disease - COVID-19
129068919 (EGFR)
05163 Human cytomegalovirus infection
129068919 (EGFR)
05165 Human papillomavirus infection
129068919 (EGFR)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
129068919 (EGFR)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
129068919 (EGFR)
01522 Endocrine resistance
129068919 (EGFR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ppam01001
]
129068919 (EGFR)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
ppam04147
]
129068919 (EGFR)
Enzymes [BR:
ppam01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
129068919 (EGFR)
Protein kinases [BR:
ppam01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
129068919 (EGFR)
Exosome [BR:
ppam04147
]
Exosomal proteins
Exosomal proteins of colorectal cancer cells
129068919 (EGFR)
Exosomal proteins of pancreatic cancer cells
129068919 (EGFR)
Exosomal proteins of bladder cancer cells
129068919 (EGFR)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
Kinase-like
Kdo
ABC1
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
129068919
NCBI-ProteinID:
XP_054427349
LinkDB
All DBs
Position
Unknown
AA seq
1209 aa
AA seq
DB search
MRPSGTVGAALLVLLAAHFPAGLALEEKKVCQGTNNKLTQLGTYDDHFLSLQRMLNNCEV
VLGNLEITYMQRDYDLSFLKTIREVAGYVLIALNVAEKIPLENLQVIRGNVLLDNTHALS
VLSNYGANHTGLRELPMRSLQEILQGAVRFSNNPTLCNMDTIQWQDIVDSSFLGNISTDF
QNKPSSSCQKCDPSCPNGSCWGAGKENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCASG
CTGPRESDCLVCRRFRDEATCKDTCPPLMLYNPTTYQVDVNPDGKYSFGATCVKKCPRNY
VVTDHGSCVRACGSDSYEVEEDGVRKCKKCEGPCRKVCNGIGIGEFKDTLSINATNIKHF
QNCTSISGDLHILPVAFRGDSFTRTKPLDPKELDILKTVKEITGSLLIQAWPENRTDLHA
FENLEIIRGRTKQHGRFSFAVVGLNIASLGLRSLKEISDGDVVISGNRHLCYADTVNWKR
LFGTSSQKTKIENNKNKEDCRAQGHVCNPLCSSEGCWGPGPRDCMSCRNVSRDKECVEKC
NILEGEPREFQENSECIQCHPECLPQPMNVTCTGHGPDKCVQCAHYIDGPHCVSTCPAGV
MGENNTLVWKFKDSKHVCHLCHPNCTYGCKGPGLEGCTLDRPKIPSIATGIVGGLLLVLV
VALGVGLFLRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLG
SGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMATVDHPHVCRLLG
ICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLA
ARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWS
YGVTVWELMTFGSKPYDGIPASEISTVLEKGERLPQPPICTIDVYMIMVKCWMIDADSRP
KFRELINEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALIDEEDMEDVVDADEYLIP
QQAFFHSPSTSRTPLLSSLSATSNNSTVACVDRNGTCPLKEDSFLQRYSSDPTGALTEDN
LNGTFLPAPEYINQLVPKRPAGSVQNPVYHNQPLHLAPGRDPHYQNPHSNAVGNPEYLNT
APPPNVNGAPDGPALWGQKGSHQISLDNPDYQQDFFPKEAKSNGIFKGPTAENADYLRVG
PPSSEFIGA
NT seq
3630 nt
NT seq
+upstream
nt +downstream
nt
atgcgaccctccgggacggtgggagccgcgctcctggtgctgctggctgcgcacttcccg
gcggggctggcgctggaggaaaagaaagtttgccaggggaccaataacaagctgacgcag
ctgggcacttatgacgaccacttcctgagcctccagaggatgctgaacaactgcgaggtg
gtcctggggaacctggaaatcacctacatgcaaagggattacgacctttccttcctgaag
accatccgggaggtcgccggctacgtcctcattgccctcaacgtggcggagaagatccct
ctggaaaacctgcaggtcatcagaggaaacgtgctcttagacaacacgcacgccttgtcc
gtcttgtccaactacggagccaaccacacgggcctgcgggagctgcccatgaggagcctg
caggaaatcctgcaaggcgccgtgcgattcagcaacaaccccaccctctgcaacatggac
accatccagtggcaggacatcgtcgacagcagttttctgggcaacatatcgacggacttt
cagaacaaaccatccagcagctgccaaaagtgtgatccaagctgccccaacgggagctgc
tggggtgcgggaaaggaaaactgtcagaaactgaccaaaatcatctgtgcccagcagtgt
tcagggcgctgccgcggcaagtctcccagcgactgctgccacaaccagtgtgcctccggc
tgcacagggccccgcgagagcgactgtctggtgtgccgcaggttccgggacgaggccacg
tgcaaggacacctgcccgcccctcatgctctacaaccccaccacgtaccaggtggacgtc
aaccccgacggcaaatacagctttggcgccacctgcgtgaagaaatgtccccgtaactac
gtggtgacagaccacgggtcgtgcgtccgggcctgcggctcggacagctacgaggtggag
gaggacggcgtccgcaagtgcaaaaagtgtgaagggccctgtcgcaaagtctgtaacgga
ataggcatcggagaattcaaggacaccctttccataaatgccacgaacatcaaacacttc
cagaactgcacgtccatcagtggagaccttcacatcctgccggtggcttttcggggtgac
tccttcacacgcacgaagcctctggacccaaaggagctggacattctcaagactgtaaag
gagatcacagggtctttgctgatccaggcctggccggagaacaggacggacctgcacgcg
ttcgagaacctagagatcatacgtggcaggacgaagcagcatggccggttttctttcgcg
gttgtcgggctgaacatcgcatccttggggctacgctccctgaaggagattagcgacgga
gacgtggtgatttcgggcaaccgccacctgtgctatgcagatactgtaaactggaaaagg
ctctttgggacctcgagtcagaaaaccaagatcgaaaacaacaaaaacaaagaagactgc
agggcccaaggccacgtctgtaacccgctgtgctcgtccgaggggtgctggggcccgggg
ccccgggactgcatgtcttgccgaaacgtcagccgtgacaaggaatgtgtggagaagtgc
aacattttggaaggcgagcccagggagttccaggagaattccgagtgcatccagtgccat
ccggagtgcctgccgcagcccatgaacgtgacctgcacaggacacggaccggacaagtgc
gtacagtgtgcccactacatcgatggccctcactgtgtcagcacctgcccggctggggtc
atgggcgaaaacaacacgctggtctggaagttcaaggacagcaaacacgtctgccacctg
tgccatccaaactgtacctacggctgcaagggaccgggtctcgaaggatgcaccctagac
aggcccaagatcccatccatcgccacgggcatcgtgggcggcctcctcttggtgctggtg
gtggccctcggggtgggcctgttcctgcgcaggcgccacatcgtccggaagcgcacgctg
cggaggctgctgcaggagcgggagctcgtggagcccctcacgcccagcggagaagcgccc
aaccaagctctcctgaggatcttaaaggaaacagaattcaagaagatcaaggtgctgggc
tccggtgcgttcggcaccgtgtacaaggggctgtggattccagagggcgagaaggtgaaa
atccctgtggccatcaaggaattaagagaagccacatctccgaaagccaacaaggaaatt
ctcgatgaagcctacgtgatggccaccgtggaccacccccacgtgtgccgcctgctgggc
atctgcctgacctccacggtccagctcatcacgcagctcatgcccttcggctgcctgctg
gactacgtccgcgagcacaaggacaacatcggctcccagtacctgctcaactggtgtgtg
cagatcgccaagggcatgaactacctggaggaccggcgcctggtgcaccgggacctggcg
gccaggaacgtcctggtgaagacgccgcagcacgtcaagatcacggacttcgggctggcc
aagctgctgggcgcggaggagaaagagtaccacgcggagggaggcaaagtgcccatcaag
tggatggctttggaatctattttgcaccgcatttatacccaccaaagtgacgtctggagc
tacggggtcaccgtttgggagctgatgacctttgggtccaagccttacgatggaatcccg
gcgagtgagatctcgaccgtcctggagaaaggagagcgcctcccgcagccacccatatgc
accatcgacgtctacatgatcatggtcaagtgctggatgatagacgcagacagccgcccc
aaattccgggagctgatcaacgaattctccaaaatggcccgagacccccagcgctacctc
gtcatccagggcgacgagaggatgcacttgcccagccccaccgactccaacttctaccgc
gcgctgatcgacgaggaagacatggaggacgtcgtggacgcggacgagtacctcatcccg
cagcaggccttcttccacagcccctccacgtcccggacgcccctcctgagctccctgagc
gcaaccagcaacaactccactgtggcgtgcgttgacagaaatgggacctgtcccctgaag
gaagacagcttcttgcagcggtatagctcagaccccaccggcgccttgactgaggacaac
ctcaatggcactttcctcccagcgccagaatacataaaccagctggttcccaagaggccc
gcaggctctgtccagaaccccgtctaccacaatcagcctctccatctggctcccggccga
gaccctcactaccagaacccccacagcaacgccgtgggcaaccccgagtatctcaacact
gcccctcctcccaacgtcaacggcgcccccgacggccccgccctctgggggcagaaaggc
agccaccaaattagcctggacaaccccgactatcagcaggacttcttccccaaggaggcc
aagtccaacggcatctttaagggtccgacagcggaaaacgcagactacctgagggtaggc
cccccgagcagcgagtttattggagcgtga
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integrated database retrieval system
