Pseudopropionibacterium propionicum: HMPREF9154_0442
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Entry
HMPREF9154_0442 CDS
T02180
Symbol
hemD
Name
(GenBank) uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
ppc
Pseudopropionibacterium propionicum
Pathway
ppc00860
Porphyrin metabolism
ppc01100
Metabolic pathways
ppc01110
Biosynthesis of secondary metabolites
ppc01120
Microbial metabolism in diverse environments
ppc01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
ppc00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
HMPREF9154_0442 (hemD)
Enzymes [BR:
ppc01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
HMPREF9154_0442 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
HMPREF9154_0442 (hemD)
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Gp_dh_C
Motif
Other DBs
NCBI-ProteinID:
AFN45507
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Position
465726..467306
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AA seq
526 aa
AA seq
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MIHTEEPEPTGTPMGVVTFVGFGPGDPGLITWAGSREVTGADLLVVDSPTMVEELASVGI
EPLGEVVQVEADEVAQLVAAVSDGRSVVRLVEGDFFTEAGHVDVLRRLLEGKRIRTHLIP
GITTWNAALTYGAVAPTSVMGFCDASVELPGKDGWPKRGTVVIRATDESISRVVAEARAV
YGETAEVLELTGLGGTSQKTRLTTWGDLGSEPCGGPRFLLFGPGIGDVARARVDWFESKP
LFDWSVLVPRTKDEVTELTDHLARFGASTEVVATMSIEPPRTEQAMEKAVRGIVDGRFLW
VVFTSQHAVRAIVDRLAEYGLDSRALSGIQLAAVGRGTVEALGRVGLTPDLTPSEGDTAH
DLALEFPAYDDLIDPMARVLVPTADVSVADLVQGLTNLGWEVEEVTAYRTVRAAPPPAEI
RDRIKTGLFDAVVFTSSSAVRNMIGIAGKPHTTSIIAAIGQATASTCEMHGLRVDVVADS
PNFESVAVGLARFADERRADRLAQGLPDTKPSQRRRRRRRDPNRGA
NT seq
1581 nt
NT seq
+upstream
nt +downstream
nt
gtgatccacaccgaggaaccggaaccgaccgggacgcccatgggggtggtcacgtttgtc
ggtttcggccctggggaccccgggctcatcacgtgggcgggcagccgcgaggtaacaggg
gctgatcttctcgtggtcgactccccgaccatggtggaagaactcgcctcggtcggtatc
gaacccttgggcgaggtcgtccaggtcgaggccgacgaggtggcccagttggtcgctgcc
gtgagcgacgggcgttccgtagtgaggctcgtcgagggggacttcttcaccgaggccggg
cacgtggacgttctgcggcggctcctggagggcaagcgcatccgcacccacctgattccc
ggaatcacgacctggaacgcggccctgacctacggggccgtcgctcccacttctgtgatg
ggtttctgcgacgcctccgtcgagctgcccggcaaggatggctggcccaagcgcggcacc
gtggtgatccgtgccaccgacgagtcgatttcccgggtggtcgctgaggcccgagccgtc
tatggggagaccgccgaggtgctggagttgaccgggctcggcggcacctcccagaaaacc
cgcctgaccacgtggggtgatctcggatccgaaccctgcggtgggccgcggttcctgctg
ttcggtcccggcatcggtgacgtcgcccgcgcccgcgtcgactggtttgagtccaaaccg
ctgttcgactggagcgttctcgtgccgcgcaccaaggacgaagtcacggagctgaccgat
cacctggcccgtttcggggcatccaccgaggtggtggcgacgatgtccatcgaaccgccc
cgcacggaacaggccatggagaaggcggttcgcggcatcgtcgacgggcgtttcctgtgg
gtggttttcacctcccaacacgcggtgcgggccatcgtcgacagactcgcggagtatggc
ctggattcgcgtgccctctccggtatccaactggcggcggtcggccgcggcacggtggag
gccctcggccgggtcggcctcacccccgacctgacaccgtcggagggcgacaccgcccac
gacctggcgttggagttccccgcctacgacgacctgatcgaccccatggcgcgggtgctc
gtgccgaccgccgacgtgtcggtggcggatctggtgcagggcctgacgaatctcggctgg
gaggtcgaggaggtcaccgcctaccgcacggtgcgggccgccccgccgcccgccgagatc
agggaccgcatcaagaccgggttgttcgacgcggtggtgttcacctcgtcgtcggcggtg
cgcaacatgatcggcatcgcgggcaaaccccacacgacctccatcatcgcggccatcggg
caggcaaccgcctcgacctgcgagatgcacggcctcagggtggatgtggtggcggactcc
ccgaacttcgaatcggtggccgtcggtctggcgcgtttcgcggacgaacgccgcgccgac
cggctggcgcaggggctgccggacacgaaaccctcccagcggcgacgccggcgccgcagg
gaccccaaccggggggcttga
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