Pimephales promelas (fathead minnow): 120493136 Help Entry 120493136         CDS       T08155                                  Symbol jak1 Name (RefSeq) tyrosine-protein kinase JAK1   KO K11217   Janus kinase 1 [EC:2.7.10.2] Organism pprm  Pimephales promelas (fathead minnow) Pathway pprm04217   Necroptosis pprm04620   Toll-like receptor signaling pathway pprm04621   NOD-like receptor signaling pathway pprm05168   Herpes simplex virus 1 infection Brite KEGG Orthology (KO) [BR:pprm00001]  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     120493136 (jak1)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     120493136 (jak1)    04621 NOD-like receptor signaling pathway     120493136 (jak1)  09160 Human Diseases   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     120493136 (jak1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:pprm01001]     120493136 (jak1) Enzymes [BR:pprm01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      120493136 (jak1) Protein kinases [BR:pprm01001]  Non-receptor tyrosine kinases   JAK family [OT]    120493136 (jak1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase FERM_F2 Jak1_Phl FERM_F1 ABC1 SH2 Motif Other DBs NCBI-GeneID:  120493136 NCBI-ProteinID:  XP_039547562 LinkDB All DBs Position Unknown AA seq 1152 aa AA seqDB search MLKPTVMELGKLCGKMKKQRKAEMTVPTVRKGLEIHFYLPETHQLEYFKDCHTAEDLCVE AAKKCHISPLCHNLFALYEESQDLWYAPNHVFKITEETSIKLHYRMRFYFTNWHGTNELE SPVWRHSLSKKGVLNSQKGTEGTPLLDAASLDYLFAQGQYDFLRGLAPVRTPQSEAELQE IENECLGMAVLAITHHAKGNDLPLSGAGAETSYKRFIPDSLNRTFKQRNFLTRIRINNVF KNFLNEFNSKTIQDSNITLYDLKVKYLSTLETLTQGLGRETVEPKILKVSGENEGSPAHT LPLGDDGRGYEVQVSGTTGISWRRKFVPNLLIVKDKPKSKKNKADNKQKTEKKKETGWTI FSDFYEITHIVIKESCVTIYRQDNKTMELDLFFRDAALSFAAMVDGYFRLTVDAHHYLCT EVAPSSVVQNLENGCHGPLCTEYAIHKLRQEGNEEGTYILRWSCTDYNYIIMTVVCIEMD LCESRPIPQYKNFQIETSPQGYRLFGTETFRPALKELLEHLQGQSLRTENLRFQLRRCCP PQPREISNLLVMTTNREPAPQRQNQVSQLSFHRILKEEIEQGEHLGRGTRTNIYAGVLKL KSEDDDDMGGYSQEVKVVLKVLGSGHRDISLAFFETASMMRQISHKHIALLYGVCVRHQE NIMVEEFVQYGPLDLFMRRQTTTLSTAWKFQVAKQLASSLSYLEDKKLVHGYVCCKNILV ARDGLDGEGGPFIKLSDPGIPITVLSREECVDRIPWIAPECVQDTANLSVAADKWGFGTT LWEICYNGEIPLKDKKLTEKERFYAAQCQLATPDCQELAKLMTHCMTYDPRQRLFFRAIV RDIVMVEEQNPSIQPVPMLEVDPTVFEKRFLKKIRDLGEGHFGKVELCRYDPRGDRTGEL VAVKSLKPENREEQSSNLWCEIDILRELYHENIVKYKGICNEEGGRSIKLIMEFLPAGSL KEYLPRNKAHIDLKTLLNYSVQICQGMDYLGSRNYIHRDLAARNVLVENESTVKIGDFGL TKSIKDNEGYYTVKDDLDSPVFWYAPECLIHCKFYRASDVWSFGVTMYELLTYCDASCSP MSVFLKMIGPTQGQMTVTRLVKVLEEGKRLPKPDGCSERLYNLMRKCWEATPEKRIDFKS LIANFQQMLDNQ NT seq 3459 nt NT seq  +upstreamnt  +downstreamnt atgcttaaaccaacagtcatggagctgggcaagctatgtgggaagatgaaaaaacagagg aaggcagagatgactgttccgactgtcaggaaaggactggagatccacttctacctgcct gaaacacaccagctcgagtatttcaaagactgccatactgcggaggacctgtgcgtggag gctgccaagaaatgccacatctcacctttatgccacaacctgtttgcactgtatgaagag agccaggatctctggtatgctcccaatcatgtgttcaagatcactgaggagaccagcatc aaactccactaccgtatgaggttttatttcacaaactggcatggcaccaatgagttggag tctcctgtttggagacactcactgagtaagaaaggtgttttgaactctcagaaggggact gaggggacacctctactagatgctgcatctcttgattacctatttgcacaggggcagtat gacttcctgaggggactggctcctgtgcgcactccccagagcgaggcagagcttcaagag atagagaacgagtgtttgggaatggcagttttggctattacccatcatgccaagggcaat gacctgcccttatcaggagctggagctgagaccagctacaagcgcttcattccggacagt cttaaccgcacctttaagcagcggaactttctcacacgcatacgcatcaacaatgtcttc aagaattttctcaatgagttcaatagcaagaccatccaggacagcaacattaccctctat gacctgaaggtcaagtatctttccactctggaaacgctgacccagggcttgggtcgagag actgttgagcctaaaatcctgaaagtatcaggcgagaatgagggctctccggcacacaca cttcccttaggggatgacggacggggatatgaggtgcaagtatctggcaccactgggatc tcctggaggagaaagtttgtaccgaatcttctgatagtgaaagacaaacccaagtctaaa aagaacaaggctgacaacaagcagaagactgaaaaaaagaaagaaaccggatggaccatt ttctcagacttttacgaaatcacccacattgtcattaaggagtcgtgtgtaaccatttac agacaagacaataaaaccatggagttggatctgttttttcgtgatgcagccctgtccttt gctgcaatggtggacggatacttcagattgactgtagatgcccatcattacctgtgcact gaagtcgcaccctcatcagttgtccagaatttagaaaatggctgtcatgggcctctctgt acagagtatgcaattcataaactccgtcaggagggaaatgaagaaggaacctacatcctg cgctggagctgcacagattataactacatcatcatgactgttgtctgcattgagatggac ctgtgtgagtccagaccgattccccagtataaaaacttccaaattgaaacaagccctcag ggctacagactgtttgggaccgagacgttccggcccgcactaaaggagcttctggagcac ttgcagggccaaagcctacgcacagagaacctgcgcttccagctgcgccgctgctgccca ccacaacccagagaaatttccaacctattagtgatgaccacaaaccgagagcccgccccg cagagacaaaatcaagtcagccagctgagtttccaccgcatccttaaggaagagattgaa cagggtgagcatttgggccggggcacaaggacaaacatctatgctggtgttctgaagctg aagagtgaggatgatgatgacatgggaggatactcacaggaggtgaaagtggtgttgaaa gtgctgggctcaggacacagagatatctctctggctttctttgagacagctagcatgatg cgtcagatctctcacaaacacatcgcactgctctacggagtgtgtgttcgccaccaggag aatatcatggtggaagagtttgttcaatatggtcctctggatctgttcatgcgcagacaa accacgactctcagcaccgcatggaagttccaggttgccaaacaattggctagctccctc agctatctggaggataagaagctggttcatggatatgtgtgctgtaagaacattctggtg gctcgagatggtctggatggagagggaggacccttcattaaactgagtgaccctggcata cccattactgtccttagcagagaagaatgtgtggacaggattccttggattgctcccgag tgtgtacaggacactgctaatctgagcgtagcagcggataagtggggctttgggacaact ctgtgggagatctgttacaatggagagatacctctcaaagacaagaaactcacggagaag gaaaggttttacgcagcacagtgtcagttggcaacccctgattgccaggagctggccaag ctcatgacccactgtatgacctacgaccctcggcagagactgttcttcagggccattgtc agggacattgtcatggtggaggaacagaacccatccattcagcctgttcccatgctagag gtggaccccacagtgtttgagaagaggttcctcaagaagatcagagaccttggagagggt cattttggaaaggtggagttgtgcagatatgacccgcggggagatcggactggagagctg gtggccgtgaagtctctaaagccagagaaccgagaagagcagagcagtaacctgtggtgt gagattgacatcctgagagaactttaccacgagaacattgttaaatacaagggcatttgc aatgaagagggtgggagatccattaagctcatcatggagtttttaccggcaggcagtctg aaggaataccttcccagaaacaaagctcacatagaccttaaaacccttctcaactattct gtacagatctgccagggcatggactacctgggctctcgcaactacatccacagagacctg gcagcccgcaatgttctggtggagaatgaaagcacggtcaagatcggagacttcggcctg accaaaagcattaaggataatgagggttactacacggtgaaagacgatctggacagtcca gtgttctggtatgctccagagtgcctgatccactgcaagttctacagggcgtctgatgtc tggtcttttggagtgaccatgtatgagctcctcacgtactgtgatgcctcgtgcagccct atgtcggtgttcctaaagatgattggtccaacacagggccagatgactgttacccgattg gtcaaagtcctggaggaggggaagagacttccgaagccagatggctgctcagaaaggttg tacaatctgatgaggaaatgctgggaggcaacacctgaaaaaaggatcgacttcaaaagc ctgattgccaactttcagcagatgcttgacaatcagtaa

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