Paenibacillus protaetiae: ET464_00865
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Entry
ET464_00865 CDS
T06829
Symbol
cobA
Name
(GenBank) uroporphyrinogen-III C-methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
pprt
Paenibacillus protaetiae
Pathway
pprt00860
Porphyrin metabolism
pprt01100
Metabolic pathways
pprt01110
Biosynthesis of secondary metabolites
pprt01120
Microbial metabolism in diverse environments
pprt01240
Biosynthesis of cofactors
Module
pprt_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
pprt00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
ET464_00865 (cobA)
Enzymes [BR:
pprt01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
ET464_00865 (cobA)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
ET464_00865 (cobA)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
DAHP_snth_FXD
Motif
Other DBs
NCBI-ProteinID:
QAY65150
UniProt:
A0A4P6EQB6
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All DBs
Position
207542..209104
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AA seq
520 aa
AA seq
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MEHKGTVYLVGAGPGDPKLITVRGLEVLRKSDVVVYDRLASPRLLQHLKPGTEKIYVGKL
PDRHTMKQEQINQLLVDLALQGKTVTRLKGGDPTIFGRVGEEAELLQEHGITFEIVPGIT
SAIAVPAYAGIPVTHRDLASSLSIITGHESPEKLDRSIHWDKVTNATGTLVFLMGVSKVG
YIAEQLIRHGKPPETPVALIRWGTRPEQETITGTLATIERIVKEAGFQPPAVIVVGEVVL
QRDKLQWVERKPLFGMRVLITRARSQASELAALIEELGGEPCEFPVIETRMTEGGHAAEA
IGGALQQAEQYHWLLFTSVNGVEYFFEWLKRLGVDIRRFHAARIAAVGPKTAQALEAKGL
LPVSLPGQFQAEGLLERLKGEIAPGQKVLLPRGNLARDLLPKELEAGGIAAVPIDVYETV
LAENQDEYALEALREREIHMITFTSSSTVNNLLELLKRSGIDQPAKLLEAVPVASIGPQT
TKAAEAAGLEVAIEPDTATIEALVAAIVQYRLTERSRMNE
NT seq
1563 nt
NT seq
+upstream
nt +downstream
nt
atggagcataaaggaacggtatatttggttggcgcaggaccgggagatccgaagctgatt
accgttcgcggcttggaagtgctccgcaaaagcgacgttgttgtatatgaccggctggca
agcccaaggctgcttcagcatttgaagccgggaacggaaaaaatatatgtcggcaagctg
ccggacaggcatacgatgaagcaggagcaaatcaatcagctgcttgtcgatttggctttg
caggggaaaacggtaacccggcttaaaggcggcgacccgacgatttttggccgggtcggc
gaagaggcggaactgctgcaagagcacggaataacatttgagattgtgccgggcattact
tcggctatcgctgtgccggcgtatgccggcatcccggtgacgcaccgcgatcttgcatcg
tcgctgtcgatcattacaggccacgaaagcccggaaaagctggaccgttccattcattgg
gacaaggtgacgaacgctaccggaacgcttgtttttctgatgggcgtctccaaagtcggc
tatatcgccgagcagctgatccggcacggcaagccgcctgagacgccggtagccctgatc
cgctggggaacaaggccggagcaggagaccattaccggaacgcttgcgacgatagaacga
atcgttaaagaagcgggctttcagccgccggccgttatcgtggtcggggaggttgtgctt
cagcgcgacaagctgcaatgggtggagcgcaagccgctgtttggcatgcgcgtgctcatt
acacgcgcccggtcgcaggctagcgagctggccgccctcatcgaagagctgggcggcgag
ccgtgcgaatttcctgtcattgaaaccagaatgacagaaggcgggcatgcggcagaagct
atcggcggcgcgcttcagcaagccgaacaatatcactggctgctgtttacgagcgtaaac
ggcgtcgaatacttttttgaatggctgaagcgtctgggcgttgatattcgacgtttccat
gcggcccgtattgccgctgtcggccccaagacggcgcaagcgctggaagcgaaagggctg
ctgcctgtcagcctgcccggtcaattccaggcggaaggcttgctggagcggctgaaaggc
gaaatcgcccccggccaaaaggtgcttttgccgagaggcaatctggcgcgcgacctgctt
ccgaaagagctggaagccggcggtattgctgcggttccgattgatgtatacgaaaccgtg
cttgcggaaaaccaagacgaatatgcgcttgaggcgcttcgcgagcgcgaaatccatatg
attacgtttaccagctcctccacggtaaacaacctgctcgagctgctgaagcggagcgga
atagaccagccggcgaagctgctggaagccgtgcctgtcgcttcgattggcccgcaaacg
actaaggcggctgaagcagcggggcttgaagttgcaattgagccggacacggcgaccatc
gaggcattggtcgccgctattgtgcaatacaggctgacggaacgcagccgcatgaatgaa
tga
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