KEGG   Pan paniscus (bonobo): 100981220
Entry
100981220         CDS       T02283                                 
Symbol
PDPK1
Name
(RefSeq) 3-phosphoinositide-dependent protein kinase 1 isoform X1
  KO
K06276  3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
Organism
pps  Pan paniscus (bonobo)
Pathway
pps01524  Platinum drug resistance
pps03320  PPAR signaling pathway
pps04068  FoxO signaling pathway
pps04071  Sphingolipid signaling pathway
pps04140  Autophagy - animal
pps04150  mTOR signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04152  AMPK signaling pathway
pps04210  Apoptosis
pps04360  Axon guidance
pps04510  Focal adhesion
pps04660  T cell receptor signaling pathway
pps04664  Fc epsilon RI signaling pathway
pps04722  Neurotrophin signaling pathway
pps04910  Insulin signaling pathway
pps04919  Thyroid hormone signaling pathway
pps04931  Insulin resistance
pps04960  Aldosterone-regulated sodium reabsorption
pps05145  Toxoplasmosis
pps05205  Proteoglycans in cancer
pps05208  Chemical carcinogenesis - reactive oxygen species
pps05213  Endometrial cancer
pps05215  Prostate cancer
pps05223  Non-small cell lung cancer
pps05231  Choline metabolism in cancer
pps05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    100981220 (PDPK1)
   04071 Sphingolipid signaling pathway
    100981220 (PDPK1)
   04151 PI3K-Akt signaling pathway
    100981220 (PDPK1)
   04152 AMPK signaling pathway
    100981220 (PDPK1)
   04150 mTOR signaling pathway
    100981220 (PDPK1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    100981220 (PDPK1)
  09143 Cell growth and death
   04210 Apoptosis
    100981220 (PDPK1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100981220 (PDPK1)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    100981220 (PDPK1)
   04664 Fc epsilon RI signaling pathway
    100981220 (PDPK1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    100981220 (PDPK1)
   03320 PPAR signaling pathway
    100981220 (PDPK1)
   04919 Thyroid hormone signaling pathway
    100981220 (PDPK1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    100981220 (PDPK1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    100981220 (PDPK1)
  09158 Development and regeneration
   04360 Axon guidance
    100981220 (PDPK1)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    100981220 (PDPK1)
   05208 Chemical carcinogenesis - reactive oxygen species
    100981220 (PDPK1)
   05231 Choline metabolism in cancer
    100981220 (PDPK1)
  09162 Cancer: specific types
   05215 Prostate cancer
    100981220 (PDPK1)
   05213 Endometrial cancer
    100981220 (PDPK1)
   05223 Non-small cell lung cancer
    100981220 (PDPK1)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100981220 (PDPK1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100981220 (PDPK1)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    100981220 (PDPK1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    100981220 (PDPK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pps01001]
    100981220 (PDPK1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pps04131]
    100981220 (PDPK1)
Enzymes [BR:pps01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     100981220 (PDPK1)
Protein kinases [BR:pps01001]
 Serine/threonine kinases: AGC group
  PDK1 family
   100981220 (PDPK1)
Membrane trafficking [BR:pps04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Acrosomal exocytosis proteins
    100981220 (PDPK1)
SSDB
Motif
Pfam: Pkinase PH_3 PK_Tyr_Ser-Thr Kinase-like Pkinase_fungal ABC1 Haspin_kinase APH Kdo
Other DBs
NCBI-GeneID: 100981220
NCBI-ProteinID: XP_034796859
LinkDB
Position
16:1394447..1463735
AA seq 575 aa
MARAGLRRGGQQLTADRGAQLACPVLGYDAVPIQSSVVLCSCPSPSMVRTQTESSTPPGI
PGGSRQGPAMDGTAAEPRPGAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARE
LATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSY
AKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQI
TDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPP
FRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPF
FESVTWENLHQQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSASD
TGLPQRSGSNIEQYIHDLDSNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMG
PVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNR
TYYLMDPSGNAHKWCRKIQEVWRQRYQSHPDAAVQ
NT seq 1728 nt   +upstreamnt  +downstreamnt
atggcacgggcaggactcaggagaggaggccagcagctcacagcagaccgcggggctcag
ctggcctgccctgtgcttgggtatgacgctgtgcccatccagtccagcgtggtgttatgt
tcctgcccatccccatcaatggtgaggacccagactgagtccagcacgccccctggcatt
cctggtggcagcaggcagggccccgccatggacggcactgcagccgagcctcggcccggc
gccggctccctgcagcatgcccagcctccgccgcagcctcggaagaagcggcctgaggac
ttcaagtttgggaaaattcttggggaaggctctttttccacggttgtcctggctcgagaa
ctggcaacctccagagaatatgcgattaaaattctggagaagcgacatatcataaaagag
aacaaggtcccgtatgtaaccagagagcgggatgtcatgtcgcgcctggatcaccccttc
tttgttaagctttacttcacatttcaggacgacgagaagctgtatttcggccttagttat
gccaaaaatggagaactacttaaatatattcgcaaaatcggttcattcgatgagacctgt
acccgattttacacggctgagattgtgtctgctttagagtacttgcacggcaagggcatc
attcacagggaccttaaaccggaaaacattttgttaaatgaagatatgcacatccagatc
acagattttggaacagcaaaagtcttatccccagagagcaaacaagccagggccaactca
ttcgtgggaacagcgcagtacgtttctccagagctgctcacggagaagtccgcctgtaag
agttcagacctttgggctcttggatgcataatataccagcttgtggcaggactcccacca
ttccgagctggaaacgagtatcttatatttcagaagatcattaagttggaatatgacttt
ccagaaaaattcttccctaaggcaagagacctcgtggagaaacttttggttttagatgcc
acaaagcggttaggctgtgaggaaatggaagggtacggacctcttaaagcacacccgttc
ttcgagtccgtcacgtgggagaacctgcaccagcagacgcctccgaagctcaccgcttac
ctgccggctatgtcggaagacgacgaggactgctatggcaattatgacaatctcctgagc
cagtttggctgcatgcaggtgtcttcgtcctcgtcctcacactccctgtcagcctccgac
acgggcctgccccagaggtcaggcagcaacatagagcagtacattcacgatctggactcg
aactcctttgaactggacttacagttttccgaagatgagaagaggttgttgttggagaag
caggctggcggaaacccttggcaccagtttgtagaaaataatttaatactaaagatgggc
ccagtggataagcggaagggtttatttgcaagacgacgacagctgttgctcacagaagga
ccacatttatattatgtggatcctgtcaacaaagtcctgaaaggtgaaattccttggtca
caagaacttcgaccagaggccaagaattttaaaactttctttgtccacacgcctaacagg
acgtattatctgatggaccccagcgggaacgcacacaagtggtgcaggaagatccaggag
gtttggaggcagcgataccagagccacccggacgccgctgtgcagtga

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