Pan paniscus (bonobo): 100990590
Help
Entry
100990590 CDS
T02283
Symbol
ARAF
Name
(RefSeq) serine/threonine-protein kinase A-Raf isoform X1
KO
K08845
A-Raf proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
pps
Pan paniscus (bonobo)
Pathway
pps01521
EGFR tyrosine kinase inhibitor resistance
pps01522
Endocrine resistance
pps04010
MAPK signaling pathway
pps04012
ErbB signaling pathway
pps04068
FoxO signaling pathway
pps04270
Vascular smooth muscle contraction
pps04650
Natural killer cell mediated cytotoxicity
pps04720
Long-term potentiation
pps04726
Serotonergic synapse
pps04730
Long-term depression
pps04810
Regulation of actin cytoskeleton
pps04910
Insulin signaling pathway
pps04914
Progesterone-mediated oocyte maturation
pps04928
Parathyroid hormone synthesis, secretion and action
pps05010
Alzheimer disease
pps05022
Pathways of neurodegeneration - multiple diseases
pps05034
Alcoholism
pps05160
Hepatitis C
pps05161
Hepatitis B
pps05200
Pathways in cancer
pps05205
Proteoglycans in cancer
pps05208
Chemical carcinogenesis - reactive oxygen species
pps05210
Colorectal cancer
pps05211
Renal cell carcinoma
pps05212
Pancreatic cancer
pps05213
Endometrial cancer
pps05214
Glioma
pps05215
Prostate cancer
pps05218
Melanoma
pps05219
Bladder cancer
pps05220
Chronic myeloid leukemia
pps05221
Acute myeloid leukemia
pps05223
Non-small cell lung cancer
pps05224
Breast cancer
pps05225
Hepatocellular carcinoma
pps05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
pps00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100990590 (ARAF)
04012 ErbB signaling pathway
100990590 (ARAF)
04068 FoxO signaling pathway
100990590 (ARAF)
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
100990590 (ARAF)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
100990590 (ARAF)
09152 Endocrine system
04910 Insulin signaling pathway
100990590 (ARAF)
04914 Progesterone-mediated oocyte maturation
100990590 (ARAF)
04928 Parathyroid hormone synthesis, secretion and action
100990590 (ARAF)
09153 Circulatory system
04270 Vascular smooth muscle contraction
100990590 (ARAF)
09156 Nervous system
04726 Serotonergic synapse
100990590 (ARAF)
04720 Long-term potentiation
100990590 (ARAF)
04730 Long-term depression
100990590 (ARAF)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100990590 (ARAF)
05205 Proteoglycans in cancer
100990590 (ARAF)
05208 Chemical carcinogenesis - reactive oxygen species
100990590 (ARAF)
09162 Cancer: specific types
05210 Colorectal cancer
100990590 (ARAF)
05212 Pancreatic cancer
100990590 (ARAF)
05225 Hepatocellular carcinoma
100990590 (ARAF)
05226 Gastric cancer
100990590 (ARAF)
05214 Glioma
100990590 (ARAF)
05221 Acute myeloid leukemia
100990590 (ARAF)
05220 Chronic myeloid leukemia
100990590 (ARAF)
05218 Melanoma
100990590 (ARAF)
05211 Renal cell carcinoma
100990590 (ARAF)
05219 Bladder cancer
100990590 (ARAF)
05215 Prostate cancer
100990590 (ARAF)
05213 Endometrial cancer
100990590 (ARAF)
05224 Breast cancer
100990590 (ARAF)
05223 Non-small cell lung cancer
100990590 (ARAF)
09172 Infectious disease: viral
05161 Hepatitis B
100990590 (ARAF)
05160 Hepatitis C
100990590 (ARAF)
09164 Neurodegenerative disease
05010 Alzheimer disease
100990590 (ARAF)
05022 Pathways of neurodegeneration - multiple diseases
100990590 (ARAF)
09165 Substance dependence
05034 Alcoholism
100990590 (ARAF)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100990590 (ARAF)
01522 Endocrine resistance
100990590 (ARAF)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pps01001
]
100990590 (ARAF)
Enzymes [BR:
pps01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
100990590 (ARAF)
Protein kinases [BR:
pps01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
100990590 (ARAF)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
ABC1
Pkinase_fungal
TUG-UBL1
Kdo
Motif
Other DBs
NCBI-GeneID:
100990590
NCBI-ProteinID:
XP_008962797
Ensembl:
ENSPPAG00000015632
LinkDB
All DBs
Position
X:39997026..40007783
Genome browser
AA seq
611 aa
AA seq
DB search
MEPPRGPPANGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCV
VYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHNFVRKTFFSLAFCDFCLKFLF
HGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRQQFYHSVQDLSGGSRQHEAPSNRPLNELL
TPQGPSLSPGSPRTQHCDPEHFPFPAPANAPLQRIRSTSTPNVHMVSTTAPMDSNLIQLT
GQSFSTDAAGSRGGSDGTPRGSPSPASVSSGRKSPHSKSPAEQRERKSLADDKKKVKNLG
YRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVSQPTAEQAQAFKNEM
QVLRKTRHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQ
GMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAA
EVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGCRDQIIFMVGRGYLSPDLSKIS
SNCPKAMRRLLSDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADELP
ACLLSAARLVP
NT seq
1836 nt
NT seq
+upstream
nt +downstream
nt
atggagccaccacggggcccccctgccaatggggccgagccatcccgggcagtgggcacc
gtcaaagtatacctgcccaacaagcaacgcacggtggtgactgtccgggatggcatgagt
gtctacgactctctagacaaggccctgaaggtgcggggtctaaatcaggactgctgtgtg
gtctaccgactcatcaagggacgaaagacggtcactgcctgggacacagccattgctccc
ctggatggcgaggagctcattgtcgaggtccttgaagatgtcccgctgaccatgcacaat
tttgtacggaagaccttcttcagcctggcgttctgtgacttctgccttaagtttctgttc
catggcttccgttgccaaacctgtggctacaagttccaccagcattgttcctccaaggtc
cccacagtctgtgttgacatgagtaccaaccgccaacagttctaccacagtgtccaggat
ttgtccggaggctccagacagcatgaggctccctcgaaccgccccctgaatgagttgcta
accccccagggtcccagcctttcccctggcagcccccgcacccagcactgtgacccggag
cacttccccttccctgccccagccaatgcccccctacagcgcatccgctccacgtccact
cccaacgtccatatggtcagcaccacggcccccatggactccaacctcatccagctcact
ggccagagtttcagcactgatgctgccggtagtagaggaggtagtgatggaaccccccgg
gggagccccagcccagccagcgtgtcctcggggaggaagtccccacattccaagtcacca
gcagagcagcgcgagcggaagtccttggccgatgacaagaagaaagtgaagaacctgggg
taccgggactcaggctattactgggaggtaccacccagtgaggtgcagctgctgaagagg
atcgggacgggctcgtttggcaccgtgtttcgagggcggtggcatggcgatgtggccgtg
aaggtgctcaaggtgtcccagcccacagctgagcaggcccaggctttcaagaatgagatg
caggtgctcaggaagacaagacatgtcaacatcttgctgtttatgggcttcatgacccgg
ccgggatttgccatcatcacacagtggtgtgagggctccagcctctaccatcacctgcat
gtggccgacacacgcttcgacatggtccagctcatcgacgtggcccggcagactgcccag
ggcatggactacctccatgccaagaacatcatccaccgagatctcaagtctaacaacatc
ttcctacatgaggggctcacggtgaagatcggtgactttggcttggccacagtgaagact
cgatggagcggggcccagcccttggagcagccctcaggatctgtgctgtggatggcagct
gaggtgatccgtatgcaggacccgaacccctacagcttccagtcagacgtctatgcctac
ggggttgtgctctacgagcttatgactggctcactgccttacagccacattggctgccgt
gaccagattatctttatggtgggccgtggctatctgtccccggacctcagcaaaatctcc
agcaactgccccaaggccatgcggcgcctgctgtctgactgcctcaagttccagcgggag
gagcggcccctcttcccccagatcctggccacaattgagctgctgcaacggtcactcccc
aagattgagcggagtgcctcggaaccctccttgcaccgcacccaggccgatgagttgcct
gcctgcctactcagcgcagcccgccttgtgccttag
DBGET
integrated database retrieval system