Providencia rettgeri: RB151_006570
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Entry
RB151_006570 CDS
T04571
Symbol
thrA
Name
(GenBank) Bifunctional aspartokinase/homoserine dehydrogenase 1
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
prg
Providencia rettgeri
Pathway
prg00260
Glycine, serine and threonine metabolism
prg00261
Monobactam biosynthesis
prg00270
Cysteine and methionine metabolism
prg00300
Lysine biosynthesis
prg01100
Metabolic pathways
prg01110
Biosynthesis of secondary metabolites
prg01120
Microbial metabolism in diverse environments
prg01230
Biosynthesis of amino acids
Module
prg_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
prg_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
prg_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
prg_M00526
Lysine biosynthesis, DAP dehydrogenase pathway, aspartate => lysine
Brite
KEGG Orthology (KO) [BR:
prg00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
RB151_006570 (thrA)
00270 Cysteine and methionine metabolism
RB151_006570 (thrA)
00300 Lysine biosynthesis
RB151_006570 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
RB151_006570 (thrA)
Enzymes [BR:
prg01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
RB151_006570 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
RB151_006570 (thrA)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
NAD_binding_3
ACT_7
ACT
DUF2652
Motif
Other DBs
NCBI-ProteinID:
APC10363
UniProt:
A0A1J0E351
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All DBs
Position
758416..760875
Genome browser
AA seq
819 aa
AA seq
DB search
MRVLKFGGTSVANDERVLNVADIAESKLADGQVALVLSAPAKITNHLVAMIEKTVAGQDV
ITHVNDAEMIFANLLKGLKEKQPGFEYDKLKKLTEQEFAQIKQVLHGITLLGQCPDSINA
TIICRGEKLSIAIMESVLKARGHNVTVINPVESLLAKGHYLESTVDINESTKRIAALNIP
KDHFVLMAGFTAGNDKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRLV
PDARLLKGMSYQEAMELSYFGAKVLHPRTIAPIAQFQIPCLIKNTTNLSAPGTLIGDGQT
DDSTPVKGITNLNNMAMINVSGPGMKGMVGMAARIFSVMSRKGISVVLITQSSSEYSISF
CVPHNELQRARAALEDEFYLELKDGVLDPLGVMEQLAIISVVGDGMRTLKGISARFFSAL
TRGNINIVAIAQGSSERSISAVIANEAGTTAVRLCHQMLFNAEQVIEAFIIGVGGVGNAL
IEQIHRQQQWLKQKHIDLRVCGIANSRAMLTDMQGIDLANWKAELAEAKEPFSLSRLIRL
EREYHFLNPVIIDCTSNQEIAEQYVNFLKDGFNVVTPNKKANTLSMDYYHQLRGAAESSK
RKFLYDTNVGAGLPVIENLQNLLNAGDELVHFSGILSGSLSFIFGKLDEGMSLSEATALA
KEKGFTEPDPRDDLSGMDVARKLLILAREAGYDLELQDIEIEPVLPMDFDSSGSVAEFMA
RLPQLDVQFAQRIKAAEAEEKVLRYVGLIEEGRCQVKIVAVDGNDPLFKVKNGENALAFY
TRYYQPIPLVLRGYGAGNDVTAAGVFADMLRTLSWKLGV
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgcgtgtgcttaaatttggcggtacttcggttgcaaatgacgaacgggtactaaatgtt
gctgacatcgctgaaagtaaattagcagatgggcaagtggcactggtactatcagcacca
gcaaaaatcactaaccatctggttgctatgattgaaaaaacggttgcaggtcaagatgtc
atcacgcatgtaaatgatgccgaaatgatttttgctaaccttttaaaaggattgaaagaa
aaacagcctggtttcgaatatgacaagctgaaaaaacttacagaacaagaattcgcacaa
atcaaacaagtactgcatggtattactctcctaggtcaatgccctgatagcatcaacgct
acaattatctgccgtggtgaaaagctctctattgctattatggaatctgtattaaaagct
cgtggtcataatgtgacagtgattaatccagttgaaagcctattagcaaaagggcattac
cttgaatctactgttgatataaatgaatcgacaaaacgtattgctgctttaaatattccc
aaagatcactttgtcttaatggctggttttaccgctgggaatgataaaggcgaactagtg
gtgttaggccgcaatggttctgattactccgccgcggtattggcagcttgcttacgtgca
gattgttgtgaaatttggactgatgttgatggtgtgtatacttgtgacccgcgtttagta
cctgacgcacgcttattgaaggggatgtcttatcaagaagccatggagttatcttatttt
ggcgccaaagttctccatcctcgtacaatcgctcctatcgcccaattccaaataccttgc
ctaattaaaaataccactaacctaagtgctcccggtactctgattggggatggtcaaacg
gatgacagcacaccagttaaggggatcactaacttaaataacatggcaatgatcaacgta
tcggggcctggtatgaaaggaatggtgggcatggctgcacgtattttctctgtcatgtca
cgtaaaggcatttcagtcgtgttgatcacccaatcttcatcagagtacagcatcagtttc
tgtgtgccacataatgaactacagcgtgctcgcgctgcactagaagatgaattctattta
gagttgaaagatggcgtattagacccactgggcgtgatggagcaattagcgattatttct
gtagtcggtgatggcatgcgtacattgaaaggtatttcagcgcgctttttctctgcattg
acccgtggcaatatcaatattgttgctattgcacaaggctcatctgagcgctctatttca
gccgtaattgcgaacgaggcgggaaccacggcggtacgtctttgtcaccaaatgttgttc
aatgcagagcaagtgattgaagcctttatcatcggagtcggtggggtgggaaatgcattg
attgaacaaatacaccgtcagcaacaatggttgaagcaaaagcatatcgacctgcgtgtg
tgtggtatagcaaactcacgtgcaatgttaacggatatgcaaggcattgatttagctaac
tggaaagctgaattagcggaagcaaaagaaccttttagcttaagtcgtttgatccgttta
gaacgcgagtatcatttcttaaaccctgtgattatcgattgtacttccaatcaagaaatt
gcagagcaatatgtgaatttcttaaaagatggttttaacgtcgtcacgccaaataaaaaa
gccaatacattatccatggattactaccaccaattgcgtggtgcagcagaaagctcgaaa
cgtaaatttctctacgatacaaacgttggtgcgggcttacctgttattgaaaatttacaa
aatttgctcaatgcaggggatgaattagttcactttagtggtattttatcgggctcactg
tcctttatctttggtaagcttgatgagggcatgtctttatctgaggcaacggcgctggca
aaagagaaaggctttacagaaccagaccctcgcgatgatttatccggtatggacgtagca
cgtaaattattgattttagcccgcgaagcaggttatgacttagagctacaagatattgaa
attgaacctgttttacctatggatttcgatagcagcggctctgttgctgaatttatggct
cgtttaccacaattagatgtacagtttgctcagcgtataaaagccgcagaagcagaagaa
aaagtgttacgctatgttgggttaattgaagaagggcgctgtcaggttaaaattgttgct
gttgatggcaatgacccactcttcaaggttaaaaatggcgaaaatgcactggctttctat
acacgctattaccaaccaattcctttagtcttaaggggttatggcgcaggtaatgatgtt
actgctgctggtgtatttgcagatatgctgcgtaccctttcatggaaattgggagtttaa
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