Phodopus roborovskii (desert hamster): 127215967 Help Entry 127215967         CDS       T08852                                  Symbol Acacb Name (RefSeq) acetyl-CoA carboxylase 2   KO K01946   acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15] Organism prob  Phodopus roborovskii (desert hamster) Pathway prob00061   Fatty acid biosynthesis prob00620   Pyruvate metabolism prob00640   Propanoate metabolism prob01100   Metabolic pathways prob04152   AMPK signaling pathway prob04910   Insulin signaling pathway prob04920   Adipocytokine signaling pathway prob04922   Glucagon signaling pathway prob04931   Insulin resistance prob04936   Alcoholic liver disease Brite KEGG Orthology (KO) [BR:prob00001]  09100 Metabolism   09101 Carbohydrate metabolism    00620 Pyruvate metabolism     127215967 (Acacb)    00640 Propanoate metabolism     127215967 (Acacb)   09103 Lipid metabolism    00061 Fatty acid biosynthesis     127215967 (Acacb)   09110 Biosynthesis of other secondary metabolites    00254 Aflatoxin biosynthesis     127215967 (Acacb)  09130 Environmental Information Processing   09132 Signal transduction    04152 AMPK signaling pathway     127215967 (Acacb)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     127215967 (Acacb)    04922 Glucagon signaling pathway     127215967 (Acacb)    04920 Adipocytokine signaling pathway     127215967 (Acacb)  09160 Human Diseases   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     127215967 (Acacb)    04931 Insulin resistance     127215967 (Acacb) Enzymes [BR:prob01000]  2. Transferases   2.1  Transferring one-carbon groups    2.1.3  Carboxy- and carbamoyltransferases     2.1.3.15  acetyl-CoA carboxytransferase      127215967 (Acacb)  6. Ligases   6.3  Forming carbon-nitrogen bonds    6.3.4  Other carbon-nitrogen ligases     6.3.4.14  biotin carboxylase      127215967 (Acacb)   6.4  Forming carbon-carbon bonds    6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)     6.4.1.2  acetyl-CoA carboxylase      127215967 (Acacb) BRITE hierarchy Motif Pfam:  ACC_central Carboxyl_trans CPSase_L_D2 ACCA_BT Biotin_carb_N Biotin_carb_C Biotin_lipoyl ATP-grasp ATP-grasp_3 Dala_Dala_lig_C Motif Other DBs NCBI-GeneID:  127215967 NCBI-ProteinID:  XP_051032427 LinkDB All DBs Position Unknown AA seq 2453 aa AA seqDB search MLLLLLTCLLFSCLTFSWLKIWGTMTDSKPPTKSEVEETFPASDSSGEPLQKHGEDASWQ RDTPPPPPSCQKPPRNPLPSNDTWPSPELQTNGTAAQGAEVPDTNGLSFPARPPGQQARS PSREDKKQAHIKRQLMTNFILGSFDDNSSDEDPSAGSFRDSPRKGSRPSLGTLSLEAALN SSDPEAHAPTMRPSMSGLHLVKRGREHKKLDLHRDFTVASPAEFVTRFGGNRVIEKVLIA NNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADQYVPVPGGPNN NNYANVELIIDIAKRIPVQAVWAGWGHASENPKLPELLRKQEIAFLGPPSEAMWALGDKI ASTIVAQTLQIPTLPWSGSGLTVEWTEDPREQGKCISVPEDVYERGCVRDVEEGLEAAKK VGFPLMIKASEGGGGKGIRKAESEEDFPMLFRQVQSEIPGSPIFLMKLAQNARHLEVQIL ADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIAAPEVFEFMEQCAVLLARTVGYVSAGTV EYLYSQDGGFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDIRLLYGES PWGVSPIYFENPLSPPSARGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSV AAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLVNLLETENF QNNDIDTGWLDHLIAERVQAEKPDIMLGVVCGALNVADAMFRTCMTDFLHSLERGQVLPA DSLLNIVDVELIYGGIKYILKVARQSLTMFVLIMNNWHIEIDVHRLNDGGLLLSYNGSSY TTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLIQYTVEDGGHVEAGSSFAEME VMKMIMTLSAQESGRVRYVKRPGVVLEAGCVVARLELDDPSKVHAAQPFTGELPAQQTLP ILGEKLHQVSHSVLENLTNVMSGYCLPEPFFSTKLKDWVQKLMMTLRHPSLPLLELQEIM TSVAGRIPAPVEKAVRRVMAQYASNITSVLCQFPSQQCWPSGMLGKHSTTELHPELLKIA VILDCHAATLQRKADREVFFMNTQSIVQLVQRYRSGTRGYMKTVVLDLLRRYLNVERHFQ QAHYDKCVINLREQFKPDMGPVLDCIFSHAQVAKKNQLVIMLIDELCGPDPALSDELTSI LNELTQLSRSQHCKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCPENLKK LILSETTIFDVLPTFFYHDNKVVCMASLEVYVRRAYIAYELNSLQHRELPDGTCVVEFQF MLPSSHPNRMAMPVSASNPDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEELTRNFDEV ISCFANVPKDAPLFSKARTSLYSEDGGKNLREEPIHILNVAIQCVDHLEDEALVPILRTF VQSKKHVLVDYGLRRITFLIAQEREFPKFFTFRARDEFAEDRIYRHLEPALAFQLELSRM RNFDLTAVPCANHKMHLYLGAAKVREGLEVTDHRFFIRAIIRHSDLITKEASFEYLQNEG ERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPHKIEESVRAMVMRYGSRLWKL RVLQAEVKINIHETTTGGAVPIRLFITNESGYYLDISVYKEVTDSRSGNIMFQSFGSKQG TLHGMLINTAYVTKDLLQAKRFQAQSLGTTYVYDFPELFRQALFKLWGSPEKYPQDILTY TELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTPEYPEGREVIVISNDITFQIGSFGIE EDFLYLRASEMARAEGIPQIFLAANSGARMGLAEEIKQIFQVAWVDPEDPHKGFRYLYLT PQDYTQISAHNAVHCKHIEDGGESRYVIMDIIGKSGSLGVENLRGSGMIAGEASLAYEKI VTISMVTCRALGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQLGGVQI MHTNGVSHVTVPDDFEGVCTILEWLSYIPKDNRSPVPIITPTDPIDREIEFVPSKAPYDP RWLLAGRPHPTLKGSWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPLGVIAVETRTVE VAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQVIRDFNQEHLPLMIFANWRGFSGGMK DMYEQMLKFGAYIVDGLRQYNQPILIYIPPCAELRGGSWVVLDSTINPLCIEMYADKESR GGVLEPEGTVEIKFRKKDLVKTMRRLDPVCKKLVGQLGAAQLSDKDRKELEGQLKAREDL LFPIYHQVAVQFADLHDTPGHMLEKGIIMDVLEWKTARTFFYWRLRRLLLEAQVTQEILR ASPELSHEHMHSMLRRWFVETEGPVKAYLWDSNQVVVQWLEQHWSAGDGLRSTIRENINY LKRDSVLKTIQSLVQGNQDVTMDCVAYLSQHLTPAERIQVAQLLSTTESPASP NT seq 7362 nt NT seq  +upstreamnt  +downstreamnt atgctcttgctcctcctgacctgcctgcttttctcctgcctgaccttttcctggttaaaa atctgggggacaatgacagactccaagccacccaccaaaagcgaggtggaggaaaccttt ccagcctcagacagctcaggggagccgctgcaaaaacacggcgaagatgccagctggcag agggacacccctcctccaccaccctcatgtcagaagcctccaaggaaccctctgccttcc aatgacacctggccatccccagaactccaaaccaacgggacagcagctcaaggcgcagag gtccctgataccaatggtttatccttcccagccaggcctccgggccagcaagccagatcc ccatccagagaggacaagaagcaggcacatatcaagagacagctgatgaccaactttatc ctgggctccttcgatgacaactcctctgatgaggaccccagcgctggctccttcagggat tctccccggaaggggagcaggcccagcctgggcaccctgtccctggaggctgcactaaac tcaagtgaccctgaggcccacgcacccactatgaggcccagcatgtctggactccacctc gtgaagagaggccgtgaacacaagaaactggatctgcacagagatttcactgtagcatcc ccagccgagtttgtcacccgctttggaggcaatagggtcatcgagaaggtgctcatcgcc aacaacggcatcgctgcagtcaagtgtatgcgctccattcgccgctgggcctatgagatg ttccggaatgaacgcgccatccggtttgtggtcatggtgacccctgaggaccttaaggcc aatgcagagtacatcaaaatggcagatcagtatgtccctgtcccaggagggcccaataac aacaactatgccaacgtggagctgatcatagacattgctaagagaattcctgtgcaggcc gtgtgggctggctggggccacgcttcggaaaaccccaaacttccagagctgctgcgcaag caggagattgctttcctaggtccccccagtgaggccatgtgggctctgggagataagatc gcctccaccattgtagcccagacattgcaaatcccgaccctcccctggagcggaagcggc ctcacagtggagtggacggaggatccccgggagcagggcaaatgcatcagtgtcccggaa gatgtctatgagcgaggctgtgtgagagacgtggaggagggcttggaggcagccaaaaag gttggatttccgctgatgatcaaagcctccgaaggcggcggagggaaaggcatccgcaag gccgagagtgaggaggacttcccgatgctcttcagacaagtgcagagtgagatcccgggc tcacccatcttcctcatgaagctggctcagaatgcacggcacctggaggtccagatcttg gcagaccagtatgggaacgcggtgtccctgtttgggcgcgactgctccatccagaggcgg caccagaagatcatcgaggaggcgccagccaccattgctgctccagaagtgttcgagttc atggaacagtgtgccgtcctcctggccagaaccgtgggttacgtgagcgctgggactgtg gagtacctgtacagccaggacggcggcttccacttcctggagctgaacccgcgcttgcag gtggagcacccgtgcacagaaatgatcgcagacgtcaacctgcccgctgcgcagttgcag atcgccatgggcgtgcccctgcaccggctgaaggacatacggcttctgtatggagaatcc ccctggggagtgagccccatctattttgagaaccctctgagccctcccagtgcccgaggt cacgtcattgcggccaggatcaccagtgaaaacccggatgagggttttaagccaagctct gggacagtccaggagctgaatttccgcagcaacaagaatgtgtggggctatttcagtgtg gcagctgctggaggcttacatgagttcgcagattcccagtttgggcactgcttctcctgg ggcgagaaccgtgaagaggccatttccaacatggtagtggccttaaaggagctgtccatc cggggtgacttccggaccaccgtggagtatctcgtgaaccttctggagactgagaacttc cagaacaacgacatcgacacggggtggctggaccatctcatcgctgagcgggtgcaggca gagaagccagacatcatgctcggggtggtgtgtggggccttgaacgtggcagatgcaatg ttcagaacctgcatgacggatttcttgcactccctggaaaggggccaggtcctcccagct gattctctgctgaacattgtggatgtggagttgatctacggaggcatcaagtacattctc aaggtggcccggcagtccctgactatgttcgttctcatcatgaacaactggcacatcgag attgatgtccaccgtctgaacgatggggggcttctcctgtcctacaacggcagcagttac acaacatacatgaaggaagaggtggacagttaccggatcactatcggcaataaaacgtgc gtatttgaaaaggagaacgaccccacggtcctgaggtccccttcggctgggaagctgata cagtacacggtggaggatgggggccacgtcgaagctgggagcagctttgcggagatggag gtgatgaagatgatcatgaccctgagcgcacaggagagcggccgggtgaggtacgtcaag cgcccaggcgtcgtgctggaggctggttgcgtagtggcgaggctagaactggatgaccct tcaaaggtgcatgcggcacagccgttcacaggggaactccctgcccagcagaccctgccc atcctcggggagaagcttcaccaggtgtcccacagcgtcctggaaaatctgaccaatgtc atgagtggctattgcctgcccgagcctttcttcagcacgaagctgaaggactgggttcag aagctcatgatgacactccggcacccgtccctacctctcctggagctgcaggagatcatg accagcgtggcaggccgcatcccagcacccgtggagaaggcggtgcgcagggtcatggcc cagtatgcaagcaacatcacttccgtgttatgtcagttccccagccaacagtgctggccc tcaggcatgctaggcaagcactctaccacggagctacaccccgagctcctgaagatagcc gtcatcctggactgccacgccgccaccctgcagcggaaggcagaccgtgaggtcttcttc atgaacacacagagcattgtgcaactggtccagaggtaccgcagtgggacccggggctac atgaagaccgtggtgctggacctcctgcggaggtatctgaatgtggagcgtcatttccag caagcccactatgacaagtgcgtgatcaacctgagagagcagttcaagccggacatgggc ccggtgctggactgcatcttctcacatgcacaggtggccaagaagaaccagctggtgatc atgctgatagatgagctctgtggtccagaccccgccctgtcagacgagctgacctccatc ctcaatgagctcacacagctgagcaggagccagcactgcaaggtggccctcagggccagg caggtcctgatcgcctcccacctcccctcctacgagctgcggcacaaccaggtggaatcc atcttcctgtctgctattgacatgtatggccaccagttctgcccagaaaacctcaagaaa ttaatactttcggaaacaactatattcgacgtcctgccaaccttcttctaccacgataac aaggtcgtctgcatggcatcgctggaggtttatgtgcggagagcctacatcgcctacgag ttaaacagcttacagcaccgggagctcccagacggcacctgtgtggtggagttccagttc atgctgccctcttcccaccccaaccggatggccatgcccgtcagcgcctccaaccctgac ctgctcaggcacagcacggaactcttcatggacagtgggttctccccgctgtgtcagcgc atgggggccatggtcgccttcaggagatttgaagagctcaccaggaactttgatgaagtc atctcctgctttgccaatgtgcctaaggacgctccgctcttcagtaaggcgcgtacctcc ctgtactctgaagatggcggcaagaaccttcgagaggaacccatccacatcctgaacgtg gccatccaatgcgtggaccacctggaggacgaggcgctggtgccaattctccgtaccttt gtgcagtccaagaaacacgtccttgtggattacggactccggagaatcacattccttatt gcccaagagagagagtttcccaagttcttcacgttcagagcaagagacgagtttgcagaa gaccggatttaccgccacctagagcccgccctggctttccagctggagctgagccggatg cgcaactttgacctgacggctgtgccctgtgccaaccataagatgcatctttacctgggt gccgccaaggtgagggaagggctggaggtgaccgaccacaggttcttcatccgagccatc atccggcactccgatctgatcaccaaggaagcctccttcgagtacctgcagaatgaaggt gagcggctgctcctggaagccatggacgagctggaggtggcgttcaacaacaccagcgtg cgcaccgactgcaaccacatcttcctcaactttgtccccacggtcatcatggacccacac aagattgaggagtcggtgcgcgccatggtcatgcgttatggcagccgtctgtggaagctc cgtgtgctgcaggcggaggtcaagatcaacatccatgaaacgaccacgggcggtgctgtc cccatccgcctgttcatcaccaacgagtctggctactacctggacatcagcgtctacaaa gaagtgactgactccagatccggaaacatcatgtttcagtcctttggcagcaagcaagga accctccatgggatgctgatcaacacggcctacgtcaccaaggacctgctccaggccaaa cgattccaggcccagtctctggggaccacctatgtgtatgacttcccggagctgtttagg caggcgctctttaaactgtggggttccccagaaaagtatccccaagatatcctgacatac acagagctggtgttggactcccagggacagctggtggagatgaaccggcttcctggtggg aatgaggtgggcatggtggccttcaaaatgaggtttaagaccccggagtatccagaaggg cgtgaggtcattgtcatcagcaacgacatcaccttccaaatcggctctttcggcatagag gaggacttcctgtatctgcgggcgtctgagatggcccgggccgagggtatcccccagatc ttcctggcagccaacagtggagctcgaatgggcctggccgaggagatcaagcagattttc caagtggcttgggtggaccctgaggacccccacaaagggtttagatacctgtacctgacg ccccaggactacactcagatcagcgcccacaacgccgtacactgcaagcacattgaggat ggaggcgaatccagatacgtcatcatggacatcataggaaagagtggcagcctgggcgtg gagaacctgaggggctcgggcatgatcgcaggagaggcctccctggcttacgaaaaaatt gtcaccatcagcatggtgacctgccgcgccctcggaatcggggcctacttggtgaggctt ggccagcgggtgatccaggtggagaactctcacatcatcctcaccggagccagcgctctc aataaggtccttggaagagaagtctacacgtccaacaaccagctggggggtgtgcaaatt atgcacacgaatggggtctctcatgtcactgtgccagatgacttcgaaggggtctgtacc attctggaatggctgtcgtatataccaaaggacaatcgaagcccagtccccatcatcact cctacagaccccatcgacagggaaattgagtttgtcccatccaaagctccctatgacccc aggtggctgcttgcagggaggcctcacccaactctgaagggctcctggcagagtggattc ttcgaccatggaagtttcaaggaaatcatggcaccctgggctcagaccgtggtgactgga cgagcacggttagggggcatccctttgggggtgattgccgtagagactcggaccgtggag gtggctgtccctgctgaccccgccaacctggattccgaagccaagatcatccagcaggcg ggccaggtgtggttcccggactctgcctacaagacagcgcaggtcatcagggacttcaac caggagcatctgcccctcatgatctttgccaactggagaggcttctctggcggcatgaag gacatgtatgaacagatgctgaagtttggagcctacatcgtggatggcctccggcagtac aaccaacccattctcatctacatccctccctgtgctgagctccgtgggggctcgtgggtt gtcctggactcaaccatcaaccccctgtgcatagagatgtacgccgacaaggagagtagg gggggtgttctggagccggagggcactgtggaaattaagttccgaaagaaagatctggtg aagaccatgagaaggttagacccagtgtgcaagaagctcgtgggacagctgggggcggcc cagctttctgacaaggaccgcaaggagctagagggccagctgaaagcccgagaggacctg ctattccccatctaccaccaggtggcagtgcaattcgccgacctgcatgacacaccgggc cacatgctggagaagggaatcatcatggacgtgctggagtggaagactgcacgcaccttc ttttactggaggctgcgccggctgctgttggaagcgcaggtgacacaggagattctgcga gccagccccgagctgagccatgagcacatgcactccatgctgcgtcgctggtttgtggag accgagggtcccgtcaaggcctacctgtgggacagcaaccaggtggtggtccagtggctg gaacagcactggtcagccggggacggcctgcgctccaccatccgtgagaacatcaattac ctgaagcgggactctgtcctcaagaccatccaaagtctggttcagggaaaccaggacgtg accatggactgcgtggcatacctgagccagcacctcaccccggccgagcggatacaggtg gctcagctactatccaccacggagagcccggcttccccctga

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