Phodopus roborovskii (desert hamster): 127218827 Help Entry 127218827         CDS       T08852                                  Symbol Nos2 Name (RefSeq) nitric oxide synthase, inducible   KO K13241   nitric-oxide synthase, inducible [EC:1.14.13.39] Organism prob  Phodopus roborovskii (desert hamster) Pathway prob00220   Arginine biosynthesis prob00330   Arginine and proline metabolism prob01100   Metabolic pathways prob04020   Calcium signaling pathway prob04066   HIF-1 signaling pathway prob04146   Peroxisome prob04371   Apelin signaling pathway prob04926   Relaxin signaling pathway prob05010   Alzheimer disease prob05014   Amyotrophic lateral sclerosis prob05022   Pathways of neurodegeneration - multiple diseases prob05133   Pertussis prob05140   Leishmaniasis prob05142   Chagas disease prob05145   Toxoplasmosis prob05146   Amoebiasis prob05152   Tuberculosis prob05200   Pathways in cancer prob05222   Small cell lung cancer Brite KEGG Orthology (KO) [BR:prob00001]  09100 Metabolism   09105 Amino acid metabolism    00220 Arginine biosynthesis     127218827 (Nos2)    00330 Arginine and proline metabolism     127218827 (Nos2)  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     127218827 (Nos2)    04066 HIF-1 signaling pathway     127218827 (Nos2)    04020 Calcium signaling pathway     127218827 (Nos2)  09140 Cellular Processes   09141 Transport and catabolism    04146 Peroxisome     127218827 (Nos2)  09150 Organismal Systems   09152 Endocrine system    04926 Relaxin signaling pathway     127218827 (Nos2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     127218827 (Nos2)   09162 Cancer: specific types    05222 Small cell lung cancer     127218827 (Nos2)   09171 Infectious disease: bacterial    05133 Pertussis     127218827 (Nos2)    05152 Tuberculosis     127218827 (Nos2)   09174 Infectious disease: parasitic    05146 Amoebiasis     127218827 (Nos2)    05145 Toxoplasmosis     127218827 (Nos2)    05140 Leishmaniasis     127218827 (Nos2)    05142 Chagas disease     127218827 (Nos2)   09164 Neurodegenerative disease    05010 Alzheimer disease     127218827 (Nos2)    05014 Amyotrophic lateral sclerosis     127218827 (Nos2)    05022 Pathways of neurodegeneration - multiple diseases     127218827 (Nos2) Enzymes [BR:prob01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor     1.14.13.39  nitric-oxide synthase (NADPH)      127218827 (Nos2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1 NAD_binding_6 Motif Other DBs NCBI-GeneID:  127218827 NCBI-ProteinID:  XP_051035799 LinkDB All DBs Position Unknown AA seq 1150 aa AA seqDB search MRDGLSSACDAARPRLCRFLRRIFGPKVASRVGPASPTTQDDCKGHRPAAKHHNDSLQPL TGTVQNGPEPLDELHVSPLTRPHHVKIKNWGSGEILQDTLHHKAMSEFTCRSKSCLGSIM NPKNLIRGPRDKPISLEELLPQAIEFINQYYGSFTEAKIEEHLARVEAVTKDIETTGTYQ LTRDELIFATKLAWRNAPRCIGRIQWANLQVFDARSCSTAQDMFHHICRHLLYSTNNGNI RSAITVFPQRSDGKHDFRIWNSQLIRYAGYQMPDGTIRGDPASLEFTQLCIDLGWKPRYG RFDVLPLILQADGQDPEVFEIPPNLVLEVPMEHPKYDWFQELGLKWYALPAVANMLLEVG GLEFPACPFNGWYMGTEIGVRDFCDTQRYNILEEVGRRMGLETHTLASLWKDRAVTEINV AVLHSFQKQNVTIMDHHTASESFMKHMQNEYRARGGCPADWIWLVPPMSGSITPVFHQEM LNYVLSPFYYYQVDPWKTHIWQDGKLRPRRREIRFRVLVKAVLFASMLMRKVMASRVRAT ILFATETGKSEVLARDLAALFSYAFNTKVVCMSQYKASTLEDEQLLLVVTSTFGNGDCPS NGQTLKKALFMLRELTHTFRYAVFGLGSSMYPQFCAFAHDIDQKLSQLGASQLALTGEGD ELSGQEDAFRSWAVQTFQAACETFDVRSKHHIRIPKCYTSNVVWEPQQYRLTQSPEPLVL NKALSSIHAKNVFTMRLKSQQNLQSGKSSRTTLLVQLSFEDRQGPSYLPGEHLGIFPGNQ VALVQGILERVVDCPSPQQTVCLEVLDESGSYWVKDKRLPPCSLSQALTYFLDITTPPTQ LQLHKLARLATDEAERQRLEALCQPSEYNDWKFRNNPTFLEVLEEFPSLHVPAAFLLSQL PTLKPRYYSISSSQDHTPSEVHLTVAVVTYRTQDGQGPLHHGVCSTWLSSLKPQDPVPCF VRSVSGFQLPEDPSLPCILIGPGTGIAPFRSFWQQRLHDFQHRGLQGGRMTLLFGCRHPE EDHLYREEMQEMAHKGVLHQVHTAYSRLPGKPKVYVQDILQKQLANEVLSVLHGEQGHLY VCGDVRMARDVATTLKKLVATKLNLSEEQVEDYFFQLKNQKRYHEDIFGAVFSYGPRKGS ALEQSTSTRL NT seq 3453 nt NT seq  +upstreamnt  +downstreamnt atgcgcgacgggctgagcagcgcgtgcgacgccgcccggccacggctttgccgcttcctg cgcaggatcttcggcccgaaggtcgccagccgcgtgggcccagccagcccaacaacacag gatgactgtaagggtcacagacctgctgccaagcaccacaatgattccctgcagcccctc actgggacagtgcagaatggtccggagcccctggacgagctgcatgtgtctccattgacc cgcccacaccacgtgaagatcaaaaactggggcagtggagagattttgcaagacaccctt caccacaaggccatgtcggagttcacctgcaggtccaaatcttgcttggggtccatcatg aaccccaagaatttgatcagaggccccagagacaagcccatctccctggaggagcttctg cctcaagccattgagttcatcaaccagtattatggctctttcacagaggcaaaaatagag gaacatctggccagggtggaagccgtaacaaaggacatagaaacaacaggaacctaccag ctgacacgggatgagctcatctttgccaccaagcttgcctggcggaacgcccctcgctgc atcggcaggatccaatgggccaaccttcaggtcttcgatgcccggagctgtagcactgcc caggacatgttccatcatatctgcagacatctgctttattccaccaacaacggcaacatc aggtcggccatcactgtgttcccccagcggagtgacggaaagcatgacttccggatctgg aattcgcagctcatcaggtacgctggctaccagatgcccgacggcaccatcagaggggac cctgctagcttggagttcacccagttgtgcatcgacctgggctggaagcctcgttatggc cgcttcgatgtgctgcctctgattctgcaggctgatggccaagatccagaggtctttgaa atccctcctaaccttgtattggaggtgcccatggagcatcccaagtacgactggtttcag gagctcgggctgaagtggtatgctttgcctgccgtagccaacatgctgctggaggtgggt ggccttgaattcccagcctgccccttcaatggttggtacatgggcacggagattggcgtt cgagacttctgtgacacacagcgctacaacatcctggaggaagtgggcagaaggatgggc ctggagacccacacactggcctccctgtggaaagaccgggctgtcacggagatcaacgtg gccgtgctccatagtttccagaagcagaatgtgaccatcatggaccaccacacagcctca gagtccttcatgaagcacatgcagaatgagtaccgggcccgaggaggctgccctgcagac tggatttggctggtccctccgatgtctgggagcatcacccctgtgttccaccaggagatg ctgaactatgttctatctccattctactactatcaggttgatccatggaagacccacatc tggcaggatgggaaactgaggccgaggaggagagagatccgattcagagtcttggtgaaa gcggtgctctttgcttccatgttgatgcggaaggtcatggcttcccgagtcagagccaca atactctttgccactgagacagggaagtctgaagtgctagcccgggacctggccgccttg ttcagctatgccttcaataccaaggttgtctgcatgagccagtacaaggcaagcaccttg gaggacgagcaactactgctggtggtgacgagcacgtttgggaatggagactgccccagc aatgggcagactctgaagaaagctctgttcatgctgagagagctcacccacaccttcagg tatgccgtgtttggccttggctccagcatgtaccctcagttctgtgcctttgctcatgac atcgaccagaaactgtcccagctgggagcctctcagcttgccctgacaggagaaggagac gaactcagcgggcaagaggatgccttccgcagctgggctgtgcaaactttccaggcagcc tgtgagacatttgatgtccgaagcaaacatcacattcggatcccgaaatgctacacttcc aacgtagtctgggagccacagcaatacaggcttacccagagcccagagcccttagtcctc aacaaagctctcagcagtatacatgccaagaatgtgtttaccatgaggctgaaatcccag cagaatctgcagagtgggaagtccagccggaccaccctcctcgtccaactttccttcgag gacaggcaaggccccagctacctccctggggaacaccttgggattttcccaggtaaccag gtggccttggtccagggaatcttggagcgagttgtggattgtccttcaccccaacaaacc gtgtgcctggaggtgctggatgagagcggcagctactgggtcaaggacaagaggctgccc ccctgctcgctcagccaagccctcacttacttcctggacatcactacccctcccacccag ctgcagctccataaattagcccgcctggccacagatgaggctgaaaggcagaggctggag gccctgtgtcagccttcagaatacaatgattggaagttcagaaacaaccccacgttcctg gaggtgctggaagagttcccgtcgctgcacgtgccggctgccttcctgctgtcacagctc cctactctgaagccccgctactactccatcagctcctcccaggaccacaccccatcagag gtccacctcactgtggctgtggtcacctatcggacccaagatggtcagggtccactgcac catggtgtctgcagcacttggttaagtagcctgaagccccaggacccggtgccctgcttt gtgcgaagtgtcagtggcttccagctccccgaagacccctccctcccttgcatcctcatt gggcccggcacgggtatcgctcccttccgcagtttctggcaacagcgactccatgacttc cagcacagagggctccaaggaggccgtatgactttgctgtttgggtgccggcacccagag gaggatcacctctatcgagaagagatgcaggagatggcccacaaaggagtgcttcaccag gtgcatacagcctactcccggctgccaggcaagcccaaggtctacgtacaagacatccta cagaagcagctagccaacgaggtactcagcgtgctccatggggagcagggccacctctat gtttgtggagatgtgcgcatggctcgggatgtggctaccaccttgaagaagctggtggcc accaagctgaacttgagcgaggagcaggttgaggactatttcttccagctcaagaaccag aaacgttatcatgaagatatctttggcgcagttttctcttatgggccgagaaagggcagc gcattggagcagtccacaagcacaaggctctag

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