Phodopus roborovskii (desert hamster): 127227112 Help Entry 127227112         CDS       T08852                                  Symbol Adcy5 Name (RefSeq) adenylate cyclase type 5   KO K08045   adenylate cyclase 5 [EC:4.6.1.1] Organism prob  Phodopus roborovskii (desert hamster) Pathway prob00230   Purine metabolism prob01100   Metabolic pathways prob01522   Endocrine resistance prob04015   Rap1 signaling pathway prob04022   cGMP-PKG signaling pathway prob04024   cAMP signaling pathway prob04062   Chemokine signaling pathway prob04072   Phospholipase D signaling pathway prob04114   Oocyte meiosis prob04211   Longevity regulating pathway prob04213   Longevity regulating pathway - multiple species prob04261   Adrenergic signaling in cardiomyocytes prob04270   Vascular smooth muscle contraction prob04371   Apelin signaling pathway prob04540   Gap junction prob04611   Platelet activation prob04713   Circadian entrainment prob04714   Thermogenesis prob04723   Retrograde endocannabinoid signaling prob04724   Glutamatergic synapse prob04725   Cholinergic synapse prob04726   Serotonergic synapse prob04727   GABAergic synapse prob04728   Dopaminergic synapse prob04750   Inflammatory mediator regulation of TRP channels prob04911   Insulin secretion prob04912   GnRH signaling pathway prob04913   Ovarian steroidogenesis prob04914   Progesterone-mediated oocyte maturation prob04915   Estrogen signaling pathway prob04916   Melanogenesis prob04918   Thyroid hormone synthesis prob04921   Oxytocin signaling pathway prob04923   Regulation of lipolysis in adipocytes prob04924   Renin secretion prob04925   Aldosterone synthesis and secretion prob04926   Relaxin signaling pathway prob04927   Cortisol synthesis and secretion prob04928   Parathyroid hormone synthesis, secretion and action prob04934   Cushing syndrome prob04935   Growth hormone synthesis, secretion and action prob04970   Salivary secretion prob04971   Gastric acid secretion prob04972   Pancreatic secretion prob04976   Bile secretion prob05012   Parkinson disease prob05030   Cocaine addiction prob05031   Amphetamine addiction prob05032   Morphine addiction prob05034   Alcoholism prob05163   Human cytomegalovirus infection prob05166   Human T-cell leukemia virus 1 infection prob05200   Pathways in cancer prob05207   Chemical carcinogenesis - receptor activation prob05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:prob00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     127227112 (Adcy5)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     127227112 (Adcy5)    04371 Apelin signaling pathway     127227112 (Adcy5)    04072 Phospholipase D signaling pathway     127227112 (Adcy5)    04024 cAMP signaling pathway     127227112 (Adcy5)    04022 cGMP-PKG signaling pathway     127227112 (Adcy5)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     127227112 (Adcy5)   09144 Cellular community - eukaryotes    04540 Gap junction     127227112 (Adcy5)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     127227112 (Adcy5)    04062 Chemokine signaling pathway     127227112 (Adcy5)   09152 Endocrine system    04911 Insulin secretion     127227112 (Adcy5)    04923 Regulation of lipolysis in adipocytes     127227112 (Adcy5)    04912 GnRH signaling pathway     127227112 (Adcy5)    04913 Ovarian steroidogenesis     127227112 (Adcy5)    04915 Estrogen signaling pathway     127227112 (Adcy5)    04914 Progesterone-mediated oocyte maturation     127227112 (Adcy5)    04921 Oxytocin signaling pathway     127227112 (Adcy5)    04926 Relaxin signaling pathway     127227112 (Adcy5)    04935 Growth hormone synthesis, secretion and action     127227112 (Adcy5)    04918 Thyroid hormone synthesis     127227112 (Adcy5)    04928 Parathyroid hormone synthesis, secretion and action     127227112 (Adcy5)    04916 Melanogenesis     127227112 (Adcy5)    04924 Renin secretion     127227112 (Adcy5)    04925 Aldosterone synthesis and secretion     127227112 (Adcy5)    04927 Cortisol synthesis and secretion     127227112 (Adcy5)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     127227112 (Adcy5)    04270 Vascular smooth muscle contraction     127227112 (Adcy5)   09154 Digestive system    04970 Salivary secretion     127227112 (Adcy5)    04971 Gastric acid secretion     127227112 (Adcy5)    04972 Pancreatic secretion     127227112 (Adcy5)    04976 Bile secretion     127227112 (Adcy5)   09156 Nervous system    04724 Glutamatergic synapse     127227112 (Adcy5)    04727 GABAergic synapse     127227112 (Adcy5)    04725 Cholinergic synapse     127227112 (Adcy5)    04728 Dopaminergic synapse     127227112 (Adcy5)    04726 Serotonergic synapse     127227112 (Adcy5)    04723 Retrograde endocannabinoid signaling     127227112 (Adcy5)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     127227112 (Adcy5)   09149 Aging    04211 Longevity regulating pathway     127227112 (Adcy5)    04213 Longevity regulating pathway - multiple species     127227112 (Adcy5)   09159 Environmental adaptation    04713 Circadian entrainment     127227112 (Adcy5)    04714 Thermogenesis     127227112 (Adcy5)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     127227112 (Adcy5)    05207 Chemical carcinogenesis - receptor activation     127227112 (Adcy5)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     127227112 (Adcy5)    05163 Human cytomegalovirus infection     127227112 (Adcy5)   09164 Neurodegenerative disease    05012 Parkinson disease     127227112 (Adcy5)   09165 Substance dependence    05030 Cocaine addiction     127227112 (Adcy5)    05031 Amphetamine addiction     127227112 (Adcy5)    05032 Morphine addiction     127227112 (Adcy5)    05034 Alcoholism     127227112 (Adcy5)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     127227112 (Adcy5)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     127227112 (Adcy5)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     127227112 (Adcy5) Enzymes [BR:prob01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      127227112 (Adcy5) BRITE hierarchy Motif Pfam:  AC_N Guanylate_cyc Adcy_cons_dom TBK1_ULD GBR2_CC Motif Other DBs NCBI-GeneID:  127227112 NCBI-ProteinID:  XP_051047355 LinkDB All DBs Position Unknown AA seq 1261 aa AA seqDB search MSGSKSVSPPGYAAQTAASPAPRGGPEHRAAWGEADSRANGYPHAPGGSARGSTKRSGGA VTPQQQQRLASRWRGDDDDDPPLSGDDPLAGGFGFSFRSKSAWQERGGDDGSRGSRRQRR GAAGGGSTRAPPAGGGGGSAAAAAAAGGTEVRPRSVELGLEERRGKGRTADELEPGSGTV EDGDGSGDGGSSVGSGSGTGAVLSLGTCCLALLQIFRSKKFPSDKLERLYQRYFFRLNQS SLTMLMAVLVLVCLVMLAFHAARPPLQLPYLAVLAAAVGVILIMAVLCNRAAFHQDHMGL ACYALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLSAL HLAISLRTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQARLH SQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTS LASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEM GMDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGK AGRIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEKAMIAKMN RQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESANPEDEVDEFL GRAIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFVQI TIVPHSLFMLSFYLSCFLLLALVVFVSVIYACVKLFPTPLQTLSRKIVRSKTNSTMVGVF TITLVFLSAFVNMFMCNSKNLVGCLAEEHNITVNQVNACHVMESTFNYSLGDEQGFCGSP QPNCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELIYVLIVEVPGVTLFDNADL LVTANAIDFSNNGTSQCPEHATKVALKVVTPIVISVFVLALYLHAQQVESTARLDFLWKL QATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANF SEFYVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTY DKAGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWG NTVNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPL S NT seq 3786 nt NT seq  +upstreamnt  +downstreamnt atgtccggctccaaaagcgtgagccccccgggctacgctgcacagacagcggcttcgccg gcgccccggggaggcccggagcatcgcgccgcgtggggagaagcagattcccgcgccaat ggttacccccacgcccccggggggtctgcccgcggctctaccaagagatctggtggggcg gtgaccccacagcagcagcagcgcctggccagccgttggcgcggcgacgacgacgacgac cctccattaagcggtgatgaccctctggctgggggctttggcttcagcttccgttccaag tccgcctggcaggagcgcggtggcgacgacggcagtcgcggcagccggcggcagcggcgg ggcgcggctggagggggcagcacccgggcgccccctgcgggcggcggcggcggttcggcg gcggcggcggcggccgcaggtgggacagaggtgcgcccccgctcggtggagctgggcctg gaggaacgtcgtgggaagggccgcacggccgatgagctggagccgggcagtggcaccgtc gaggatggagacggctccggggatggcggcagttccgtggggtcaggctctgggaccggc gcggtgctgtcgctgggcacctgctgcctggctttgctgcagatattccgttctaagaag ttcccgtcggacaaactggagcggctgtaccagcgctacttcttccgcctgaaccagagc agcctcaccatgctcatggccgtgctggtgctcgtgtgcctggtcatgctggccttccac gcggcgcggcccccgctccagctaccctacctggccgtgttggcagctgctgtgggcgtg atccttatcatggccgtgctctgcaaccgtgcagccttccaccaggaccacatgggcctg gcctgttatgcactcattgcagtagtgctggccgtccaggtagtgggcctgttgctgccg cagcctcgcagtgcctccgagggcatctggtggaccgtgttcttcatctataccatctac acgctgctgcctgtgcgcatgagggccgcggtgctcagcggggtgcttctgtcggccctc cacctggccatctctctgcgcaccaacgcccaggaccagtttctgctgaagcagcttgtc tccaatgtcctcatcttctcctgcaccaacattgtgggtgtctgcactcactacccggct gaggtctcccagagacaggccttccaggagacccgggagtgtatccaggctcggctccac tcacagcgggagaaccagcaacaggagcgtctcctgctgtctgtccttccccgtcatgtt gccatggagatgaaagcagacatcaacgccaagcaggaggatatgatgttccacaagatt tacatccagaaacatgacaacgtgagcatcctgtttgctgacatcgagggcttcaccagc ctggcttcccagtgtactgcccaggaactggtcatgaccctcaatgagctctttgcccgc tttgacaagttggctgcggagaaccactgtttacggattaagatcctcggggattgttac tactgcgtctctgggctgcctgaagccagggctgaccatgcccactgctgcgtagagatg ggcatggacatgatcgaggctatctcgttggtccgagaggtgacaggagtgaacgtgaac atgcgcgtgggcattcacagtgggagagtacactgcggcgtccttggtctcagaaagtgg cagttcgacgtatggtctaacgatgttacgctggccaaccacatggaggctggtggcaaa gcgggacgaattcatatcaccaaggccacactcaactacctgaatggggactatgaggtg gagccaggctgtggtggcgagcgcaacgcctacctcaaggagcacagcatcgagaccttc ctcatcctgcgctgtacccagaagcggaaagaagagaaagccatgattgctaagatgaac cgccagagaaccaattccataggacacaacccaccccactggggagctgagcgccccttc tacaaccacttgggtggtaaccaggtgtccaaggagatgaagaggatgggctttgaagac cccaaagacaagaatgcccaagaaagtgccaaccctgaggacgaagtggacgagtttctg ggccgggccattgatgccaggagcattgacagactacggtctgaacatgtccgcaagttc ctgttgaccttcagggagcccgacttagagaagaagtactccaagcaggtggatgaccga tttggtgcctatgtggcctgtgcctcgcttgttttcctcttcatctgctttgtccagatc accatcgtgccccactccctgttcatgctgagtttctacctgtcgtgtttcctgctgctg gccttggtggtgtttgtgtcggtgatctatgcctgtgtgaagctcttccccactcccctg cagacactctccaggaagatcgtgcgatccaagacaaatagcaccatggttggggtgttc accatcaccctggtgttcctctccgcctttgtcaacatgttcatgtgcaactctaagaac ctggtgggctgcctggcggaggagcacaacatcacggtgaaccaggtcaacgcatgtcat gtgatggagtcgaccttcaactatagcctgggtgatgagcagggcttctgtggcagcccc cagcccaactgcaacttcccagagtacttcacctacagtgtgctgctcagcctgctggcc tgctccgtgttcctacagatcagctgcatcgggaagctggtgctcatgttggccatcgag ctcatctacgtgctcatcgttgaggtgcctggtgtcacactctttgacaacgctgacctt ctggtcaccgccaatgccatagacttcagcaacaacgggacttcccagtgccctgagcat gccaccaaggtggcgctgaaggtggtgacaccgatcgtcatctctgtcttcgtgctggcc ctgtatctgcatgcccagcaggtggaatccactgctcgccttgacttcctgtggaaatta caggccacagaggagaaggaggagatggaggagctgcaggcctacaacagacgcctgctg cacaacattctgcccaaggacgtagctgcccacttcctggcccgagagcggcgcaatgat gagctatactaccagtcctgcgagtgtgtggccgtcatgttcgcctccattgccaacttc tctgaattctatgtggagctagaggctaacaacgagggcgtcgagtgcctgaggctgctc aatgagatcatcgcagattttgatgagatcatcagtgaggatcggttcaggcagctggag aagatcaagaccataggtagcacctacatggctgcctctggcctcaacgattccacctat gacaaggcaggcaagacccacatcaaagctcttgcagacttcgccatgaagttgatggac cagatgaagtacatcaacgagcactccttcaacaacttccagatgaagatcgggctcaat attggacccgttgtggctggggtcattggggctcgcaagcctcagtatgacatctggggc aatacagtaaatgtggccagccgtatggacagcactggggtgcctgaccgcatccaggtc actacagacatgtaccaggtgctggccgccaacacataccagctggagtgtcggggtgtg gtcaaggtcaagggcaagggtgagatgatgacctacttcctcaatggagggcctcccctc agttag

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