Phocoena sinus (vaquita): 116744231
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Entry
116744231 CDS
T07759
Symbol
HSD11B1
Name
(RefSeq) corticosteroid 11-beta-dehydrogenase isozyme 1
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
psiu
Phocoena sinus (vaquita)
Pathway
psiu00140
Steroid hormone biosynthesis
psiu00980
Metabolism of xenobiotics by cytochrome P450
psiu01100
Metabolic pathways
psiu05204
Chemical carcinogenesis - DNA adducts
Module
psiu_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
psiu00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
116744231 (HSD11B1)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
116744231 (HSD11B1)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
116744231 (HSD11B1)
Enzymes [BR:
psiu01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
116744231 (HSD11B1)
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Gene cluster
GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
THF_DHG_CYH_C
DUF1776
Pyr_redox_2
2-Hacid_dh_C
NAD_binding_2
Pyr_redox_3
Shikimate_DH
Methyltransf_25
Pyr_redox
SIS
Motif
Other DBs
NCBI-GeneID:
116744231
NCBI-ProteinID:
XP_032469597
Ensembl:
ENSPSNG00000012538
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All DBs
Position
1:complement(148117619..148163403)
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AA seq
298 aa
AA seq
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MAFMKKYLLPILGIFLAYYYYSAKEEFRPEMLRGKRVIVTGASKGIGREMAYHLARMGAH
VVVTARSEEALKKVVSHCLELGASSAHYVAGTMENMTFAEQFVAKAGKLMGGLDMLILNH
ITNTNNPMTVFIDDIDHVRKNMEVNFLSYVVLSGAAMPMLKQSNGSIVVVSSIAGKTANP
LIAAYSASKFALDGFFSSIRVEYAVTNVNVSITLCILGLIDTETAMTGTAGIYKAEASPK
EECALEIIKGGALRQKEVYYDSSVLTPFLLGNPGRKIMEFLSLRNYNMEIFINNQVLP
NT seq
897 nt
NT seq
+upstream
nt +downstream
nt
atggcttttatgaagaaatatctcctccccattctggggatcttcttggcctactactac
tattctgcgaaggaggaattcagaccagagatgcttcgaggaaaaagagtgattgtcaca
ggggccagcaaggggattggaagagagatggcctatcatctggcgagaatgggagcccat
gtggtagtgacagcgaggtcagaagaagctctaaagaaggtggtatcccactgcctggag
ctcggtgcatcctcggcgcactacgttgctggcaccatggagaacatgaccttcgcggag
caatttgttgccaaagctggaaaactcatggggggactagacatgctcattctgaaccac
atcaccaacaccaacaaccctatgactgtattcatcgatgacattgaccacgtgcgcaaa
aacatggaggtcaacttcctgagttacgtggtcctgagcggggccgccatgcccatgctg
aagcagagcaacgggagcattgttgtcgtctcctcgatagccgggaaaacagctaatcca
cttattgctgcctattctgcaagcaagtttgctctggatgggttcttctcctctatcagg
gtggaatatgcagtgaccaatgtcaatgtgtcgatcaccctctgtatccttggcctcata
gacacagaaacagccatgacaggaactgctgggatatacaaggcagaagcatctccaaag
gaagaatgtgccctggagattatcaaagggggagctctgcgccaaaaggaagtatattat
gacagttcggtcttgactcctttcctgctgggaaatccggggaggaagatcatggaattt
ctctccttacgaaattataatatggaaatatttataaacaaccaggtacttccttag
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