Phocoena sinus (vaquita): 116762356
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Entry
116762356 CDS
T07759
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
psiu
Phocoena sinus (vaquita)
Pathway
psiu00270
Cysteine and methionine metabolism
psiu00480
Glutathione metabolism
psiu01100
Metabolic pathways
psiu01240
Biosynthesis of cofactors
psiu04216
Ferroptosis
Module
psiu_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
psiu00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
116762356 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
116762356 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
116762356 (GCLC)
Enzymes [BR:
psiu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
116762356 (GCLC)
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GFIT
Motif
Pfam:
GCS
GCS2
SANT_DAMP1_like
Motif
Other DBs
NCBI-GeneID:
116762356
NCBI-ProteinID:
XP_032505127
Ensembl:
ENSPSNG00000017555
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Position
11:63107917..63146761
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AA seq
637 aa
AA seq
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MGLLSQGSPLSWEETQRHADHVRLHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
ENRKAQLVLSGEELLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMRKRRKEATSLLGENQALCTITSFPRLGCPGFTLPEFKPNPVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPEDDEAAKASKPDHIYMDA
MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVI
SASVDDRTREERGLEPLKNNHYRISKSRYDSIDSYLSECGEKYNDIDLTKHKEIYEQLLQ
EGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVL
QGLFYFRKDICKGGNAMVDGRSKTTGSIEPAAEEYALMTIDTIINGKEGMFPGLIPILNS
YLENMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFIANHPDYKQDSVITDEMNYS
LLLKCNQIANELCECPELLGPAFRKVKYSGSKTDSSN
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atggggctactgtcccagggctcgccactgagctgggaggagacccagcgccacgccgac
cacgtgcggctgcacgggatcctccagttcctgcacatctaccacgccgtcaaggaccgg
cacaaggacgtgctcaagtggggcgacgaggtggaatacatgttggtatcttttgatcat
gaaaatagaaaagcccaactggtactgtctggagaggaacttcttgaaactctgcaagaa
aagggggaaaggacaaacccaaaccaccctaccctttggagaccagagtatgggagctac
atgatcgaggggacacctggccagccgtatggagggaccatgtctgagttcaacacggtc
gaggacaacatgaggaagcgccgcaaggaagcgacatctctgctgggggaaaaccaggcc
ctctgcacaatcacttcgtttcccagattaggctgccctgggttcacactgcccgagttc
aagcccaacccagtggaaggaggagcttccaagtccctcttctttcctgatgaagcgata
aacaagcacccgcgcttcagtaccctcaccaggaacatccggcacagaagaggagaaaag
gttgtcatcaacgttccaatatttaaggacaagaatacaccatctccatttatagaaaca
tttcctgaggatgatgaggcagcaaaggcttctaagcccgaccacatttacatggatgct
atgggctttgggatgggcaattgctgtctgcaggtaacgttccaagcctgcagcatatct
gaggccagatacctttatgatcagttggccactatctgcccaattgtcatggctttgagc
gctgcgtctcctttttaccgaggctatgtgtcagacattgattgtcgctggggcgtgatt
tctgcatctgtagatgatagaactcgggaggagagaggactggagccactgaagaacaac
cactataggatcagtaagtcccgatatgattcaatagacagttacttatctgagtgcggt
gagaaatataatgacatcgacctgacgaaacacaaagaaatctatgaacagctgttgcag
gaaggcatcgatcatctcctggcccagcacgtggctcatctcttcattagagacccgctg
actctgtttgaagagaaaatccacctggacgatgccaacgagtccgaccattttgagaat
attcagtccacaaattggcagacaatgcgatttaaacctcctcctccaaactccgacatt
ggatggagagtggaattccggcccatggaggttcagttgacagacttcgagaactccgcg
tacgtggtgttcgtggtgctgctcaccagggtgatcctttcctacaaactggactttctc
atcccgctgtcaaaggttgatgagaacatgaaagtagcacagaagcgagatgccgtcctg
cagggactgttttatttcagaaaagatatttgcaaaggtggcaacgccatggtggacggc
cgcagcaagaccacgggcagcatcgagccagcagccgaggagtacgcactcatgaccatc
gacaccatcatcaacggcaaggaaggcatgttccccgggctgatccccatcctgaactct
tacttggaaaacatggaggtggacgtggacaccagatgcagtattctgaactacctgaag
ctgattaagaagagagcatccggagaattaatgacagttgccagatggatgagggagttc
atcgcaaaccatccagactacaagcaagacagtgtaataactgacgagatgaactatagc
cttcttttaaagtgtaaccaaatcgcaaatgaattatgtgaatgcccagagttacttggg
ccagcatttaggaaagtaaagtacagtggaagtaaaactgactcttccaactag
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