Polyodon spathula (Mississippi paddlefish): 121316852
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Entry
121316852 CDS
T07273
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit-like isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
pspa
Polyodon spathula (Mississippi paddlefish)
Pathway
pspa00270
Cysteine and methionine metabolism
pspa00480
Glutathione metabolism
pspa01100
Metabolic pathways
pspa01240
Biosynthesis of cofactors
pspa04216
Ferroptosis
Module
pspa_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
pspa00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
121316852
09106 Metabolism of other amino acids
00480 Glutathione metabolism
121316852
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
121316852
Enzymes [BR:
pspa01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
121316852
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Motif
Pfam:
GCS
GCS2
mRNA_triPase
Motif
Other DBs
NCBI-GeneID:
121316852
NCBI-ProteinID:
XP_041108062
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Position
6:12658800..12698620
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AA seq
626 aa
AA seq
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MGLLTQGSPLNWEETKKYADHVRKHGIIQFLNIYNKLKDRQKDVLKWGDEVEYMLVAMDH
SNQKVRLVLSGGDILHTLQEKGENTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMGKRRREASSLLKENQTLCTITAFPRLGCPGFTFPEFDPKPVEKGASKSLFFPDEAI
NQHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPCPFIETFPTDDGEAERAALPDHIYMD
CMGFGMGNSCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGV
ISASVDDRTREERGLEPLKHNKYRISKSRYDSIDSYLSSCGEKYNDIELTIDEEINKQLL
DAGIDKLLAQHIAHLFIRDPLTLFEEKIHLDDENESDHFENIQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQRRNAV
LQGMFYFRKDIFKGCNPVVDGGASPQNGLDKEEYALMSIDTIINGKEGVFHGLIPILNCY
LENMEVDVETRCTILNYFKLIKKRASGELMTMARWMREFVANHPEYKQDSMITDKINYDL
IMKCDEIANRAARCPELLGDPINRAK
NT seq
1881 nt
NT seq
+upstream
nt +downstream
nt
atgggtttgctgacacaagggtcgccattgaactgggaagagaccaaaaagtacgcggat
catgtcagaaaacacggcatcatccaattcctaaatatttacaacaaattgaaagaccga
caaaaggacgtcctgaagtggggtgatgaggttgaatacatgttggtagcgatggatcac
agcaatcagaaagttcgcctggtgctcagtggaggtgatatcttgcacactcttcaagaa
aaaggtgaaaataccaaccccaaccacccaaccctctggaggcccgagtacggcagctac
atgattgaaggcactcctggccagccctatggaggaacaatgtctgagttcaacactgtg
gaagacaacatggggaaacgacggagggaagcctcctctttactgaaagaaaaccagaca
ctgtgcaccatcacagcattcccaagattgggctgccctggttttactttcccagagttt
gatcccaaaccagttgaaaaaggagcatccaaatctctattttttccagatgaagcaatt
aatcagcatcccaggtttagcactttgaccagaaatatccgtcacagaagaggagagaaa
gtcgtgataaatgtacccatctttaaagacaaaaacacaccatgtccttttattgagaca
ttcccaacagatgatggagaggcagaaagggcagctttaccagaccacatatacatggac
tgcatggggtttggaatgggaaactcttgtcttcaggtcacattccaagcttgtagtata
agtgaagctagatatttatatgaccagcttgccacaatatgccccattgtgatggctttg
agtgcagcttctccattttatagaggctacgtgtctgatattgactgtcgctggggagtg
atctctgcttccgtcgatgaccgaacacgtgaagagcggggtttagagcccctaaaacac
aataaatatcggatcagtaaatccagatatgattccatagacagctacctctccagttgt
ggtgaaaaatacaacgacattgaattaacaatagatgaagagatcaacaagcagctgtta
gatgcagggattgacaagctcttggcgcaacatatagcccatctttttatccgtgatcct
ttgactctctttgaagagaaaattcatctggatgatgagaatgagtccgaccattttgag
aacattcagtcaaccaactggcagactatgagatttaaacctcctcctcccaactctgac
attggatggagagtagagtttcgcccaatggaagtccagttgacagactttgaaaactca
gcatacgttgtatttgttgtattgctcacaagagtgattctgtcatacaaactagacttc
cttattccattgtcgaaggttgatgaaaatatgaaggtcgctcagagacggaatgctgtc
cttcaaggaatgttttacttcaggaaggacatttttaaaggttgtaacccagttgtcgat
ggaggtgcatcacctcaaaacggcctagacaaggaagagtatgctttgatgagcattgac
acaatcattaatgggaaggaaggtgtctttcatggtttaataccaatcctgaactgctac
ctggaaaacatggaagtagacgtagaaacgcgatgtaccatattgaattattttaaactg
ataaagaagagagcatcaggggagctgatgactatggctcgatggatgcgagagtttgtt
gcaaaccaccctgaatacaagcaggacagcatgatcacggataaaatcaactatgacctc
attatgaaatgtgacgagattgcaaatagagcagctcggtgcccagaacttctcggagat
cccataaacagggcaaaataa
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