Piliocolobus tephrosceles (Ugandan red Colobus): 111522891
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Entry
111522891 CDS
T07491
Symbol
PDE8A
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
pteh
Piliocolobus tephrosceles (Ugandan red Colobus)
Pathway
pteh00230
Purine metabolism
pteh01100
Metabolic pathways
pteh04927
Cortisol synthesis and secretion
pteh04934
Cushing syndrome
pteh05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
pteh00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
111522891 (PDE8A)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
111522891 (PDE8A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
111522891 (PDE8A)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
111522891 (PDE8A)
Enzymes [BR:
pteh01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
111522891 (PDE8A)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
PDEase_I
PAS_9
PAS
PAS_4
PAS_3
PDE8
PAS_8
Sina_ZnF
DUF5894
Motif
Other DBs
NCBI-GeneID:
111522891
NCBI-ProteinID:
XP_026304100
Ensembl:
ENSPTEG00000006777
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Position
6:complement(94728016..94890091)
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AA seq
848 aa
AA seq
DB search
MGCAPSIHISESLEVEDAPSPAASPLSSGGPRLPQGQKTAALSQTRGAGLLEPREGSGKK
VAVADVQFGPMRFHQDQLQVLLVFTKEDNQCNGFCRACEKAGFKCTVTKEAQAVLACFLD
KHHDIIIIDHRNPRQLDAEALCRSIRSSKLSENTVIVGVVRRVDREELSVMPFIAAGFTR
RYVENPNIMACYNELLQLEFGEVRSQLKLRFAYSGHFIHCVILVTGLRFLRACNSVFTAL
EKSEDAIEITSEDRVIQYANPAFETTMGYQSGELIGKELGEVPINEKKADLLDTINSCIR
IGKEWQGIYYARKKNGDNIQQNVKIIPVIGQGGKIRHYVSIIRVCSGNNKAEKIPECVQS
DTHTDNQTGKHKDRRKGSLDVKAVASRATEVSSQRRHSSMARIHSMTIEAPITKVINIIN
AAQESSPMPVTEALDRVLEILRTTELYSPQFGAKDDDPHANDLVGGLMSDGLRRLSGNEY
VLSTKNTQTVSSNIITPISLDDVPPRIARAMENEEYWDFDIFELEAATHNRPLIYLGLKM
FARFGICEFLHCSESTLRSWLQIIEANYHSSNPYHNSTHSADVLHATAYFLSKERIKETL
DPIDEVAALIAATIHDVDHPGRTNSFLCNAGSELAILYNDTAVLESHHAALAFQLTTGDD
KCNIFKNMERNDYRTLRQGIIDMVLATEMTKHFEHVNKFVNSINKPLATLEENGETDKNQ
EMINTMLRTPENRTLIKRMLIKCADVSNPCRPLQYCIEWAARISEEYFSQTDEEKQQDLP
VVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFVDLPDLMQHLDNNFKYWKGLDEMKL
RSLRPPPE
NT seq
2547 nt
NT seq
+upstream
nt +downstream
nt
atgggctgtgcccccagcatccacatatccgagagcctggaagtcgaggacgcacctagc
cccgcggcatcgccgctgtcttccggcgggccgcgccttccgcagggccagaagacggcc
gccttgtcccagacccgcggcgccggcctcttggagcctcgcgaaggcagcggcaagaag
gtagcagtagctgatgtgcaatttggccccatgagatttcatcaagatcaacttcaggta
cttttagtgtttaccaaagaagataaccaatgtaatggattctgcagggcatgtgaaaaa
gcagggtttaagtgtacagttaccaaggaggctcaggctgtccttgcctgtttcctggac
aaacatcatgacattatcatcatagaccacagaaatcctcgacaactggatgcagaggca
ctgtgcaggtctatcagatcatcaaaactctcagaaaacacagttattgttggtgtagta
cgcagggtggatagagaagagttgtccgtaatgcctttcattgctgctggatttacaagg
aggtatgtggaaaaccccaacatcatggcctgctacaatgaactgctccagctggagttt
ggagaggtgcgatcacaactgaaactcagatttgcctattctggacatttcatacactgt
gtgatccttgtgactggcttacggtttttaagggcttgtaactctgtattcactgcatta
gaaaagagtgaagatgcaattgaaattacaagtgaagaccgtgttatacagtatgcaaac
cctgcatttgaaacaacaatgggctatcagtcaggtgaattaatagggaaggagttagga
gaagtgcctataaatgaaaaaaaggctgacttgctcgatactataaattcatgcatcagg
ataggcaaggagtggcaaggaatttactatgccagaaagaaaaacggagataatatacaa
caaaatgtgaagataatacctgtcattggacagggaggaaaaattagacactatgtgtcc
attatcagagtatgcagtggcaacaataaggctgagaaaatacccgaatgtgttcagtct
gacactcatacagataatcagacaggcaaacataaagacagaagaaaaggctcactagac
gtcaaagctgttgcctcccgtgcaactgaagtttccagccagagacgacactcttccatg
gcccggatacattccatgacgattgaggcgcccatcaccaaggtaatcaatattatcaat
gctgcccaggaaagtagtcccatgcctgtgactgaagccctagaccgtgtgctggaaatt
ctaagaaccactgagttatattcaccacagtttggtgctaaggatgatgatccccatgcc
aatgaccttgttgggggcttaatgtctgatggtttgcgaagactatcagggaatgaatat
gttctttcaacaaaaaacactcaaacagtttcaagcaatataatcactcccatctccctt
gatgatgtcccaccacggatagctcgggccatggaaaatgaagaatactgggactttgat
atttttgaactggaggctgccacccacaataggcctttgatttatcttggtctcaaaatg
tttgctcgctttggaatctgtgaattcttacactgctctgagtcaacactaagatcgtgg
ttacaaattatcgaagctaattatcattcttccaatccctaccacaattctacacattct
gctgatgtgcttcatgccactgcctattttctctccaaggaaaggataaaggaaacttta
gatccaattgatgaggtcgctgcactcattgcagccaccattcatgatgtggatcaccct
gggagaaccaactccttcctgtgtaatgctggaagtgagctggccattttgtacaatgac
actgctgtgctggagagccaccatgcggccttggccttccagctgaccactggagatgat
aaatgcaatatatttaaaaacatggagaggaatgactatcggacactgcgccaggggatt
atcgacatggtcttagccacggaaatgacaaagcactttgagcatgtcaacaaatttgtc
aacagcatcaacaaacccttggcaacactagaagaaaatggggaaactgataaaaatcag
gaaatgataaacactatgcttaggactccagagaaccggactctaatcaaacgaatgctg
attaaatgtgctgatgtgtccaatccctgccgacccctgcagtactgcatcgagtgggct
gcacgcatttcagaagaatatttttcgcagactgatgaagagaagcagcaggacttacct
gttgtaatgccagtttttgacagaaatacctgcagcatccccaaatcccaaatctctttc
attgattacttcatcacagacatgtttgatgcttgggatgcctttgtagacctgcctgat
ttaatgcagcatcttgacaacaactttaaatactggaaaggactggacgaaatgaagctg
cgaagcctccgaccacctcctgaatag
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