Piliocolobus tephrosceles (Ugandan red Colobus): 111527712
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Entry
111527712 CDS
T07491
Symbol
PDE4A
Name
(RefSeq) cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform X1
KO
K13293
cAMP-specific phosphodiesterase 4 [EC:
3.1.4.53
]
Organism
pteh
Piliocolobus tephrosceles (Ugandan red Colobus)
Pathway
pteh00230
Purine metabolism
pteh01100
Metabolic pathways
pteh04024
cAMP signaling pathway
pteh04928
Parathyroid hormone synthesis, secretion and action
pteh05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
pteh00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
111527712 (PDE4A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
111527712 (PDE4A)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
111527712 (PDE4A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
111527712 (PDE4A)
Enzymes [BR:
pteh01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
111527712 (PDE4A)
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
PDE4_UCR
Motif
Other DBs
NCBI-GeneID:
111527712
NCBI-ProteinID:
XP_026311364
Ensembl:
ENSPTEG00000033684
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Position
21:complement(42461257..42507641)
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AA seq
886 aa
AA seq
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MEPPTVPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERAEPERP
PHRPIERANAMDTSDRPGLRTTRMSWPSSFHGTGTGSGGAGGGSSRRFEAENGPTPPPGR
SPLDSQASPGLVLHAGAATSQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTP
FAQVLASLRSVRSNFSLLTNVPVPTNKRSPLGGPTPVCKATLSEETCQQLARETLEELDW
CLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEI
PSPTMKEREKQQAPRPRPSQPPPPPVPHLQPMSQITGVKKLMHSNSLNNSNIPRFGVKTD
QEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYML
TLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGV
SNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDM
VLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLE
LYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADL
VHPDAQEILDTLEDNRDWYYSAIRQSPSPPPEEESRGPGHPPPPDKFQFELTLEEEEEEE
ISMASIPCTAQEALTAQGLSGAEEALDTTMAREASPAQESLDVMAQDESLEAELEEVYLT
QQAQSTGGAPVAQDEFSSQEESVVAVSQSSPSALALQSPLLPAWRTLSVSEHAPGLPGLP
STAAEVEAQREHQAAKRACSACTGTSGEDTSAFPAPGGGESGGDPT
NT seq
2661 nt
NT seq
+upstream
nt +downstream
nt
atggagcccccgaccgtcccctcggaaaggagcctgtctctgtcactgcccgggccccgg
gagggccaggccaccctgaagcctccccctcagcacctgtggcggcagcctcggaccccc
atccgtatccagcagcgcggctactccgacagcgcggagcgcgcggagccggagcggccg
cctcaccggcccatagagcgcgccaatgccatggacaccagcgaccggcccggcctgcgc
acgacccgcatgtcctggccctcgtccttccatggcactggcaccggcagcggcggcgcg
ggcggaggcagcagcaggcgcttcgaggcagagaatgggccgacaccacctcccggccgc
agccccctggactcgcaggcgagcccaggactcgtgctacatgccggggcggccaccagc
cagcgccgggagtccttcttgtaccgctcagacagcgactatgacatgtcacccaagacc
atgtcccggaactcatcagtcaccagcgaggcgcacgctgaagacctcatcgtaacaccg
tttgctcaggtgctggccagcctccggagcgtccgtagcaacttctcactcctgaccaat
gtgcccgttcccactaacaagcggtccccgctgggcggccccacccctgtctgcaaggcc
acgctgtcagaagaaacgtgtcagcagttggcccgggagacgctggaagagctggactgg
tgtctggagcagctggagaccatgcaaacttatcgctctgtcagcgagatggcctcgcac
aagttcaagaggatgttgaaccgtgaactcacacacctgtcagaaatgagcaggtcagga
aaccaggtctcagagtacatttccacaaccttcctggacaaacagaatgaagtggagatc
ccatcacccacgatgaaggaacgagaaaaacagcaagcgccgcgaccaagaccctcccag
ccacccccgccccccgtaccacacttacagcccatgtcccaaatcacaggggtgaaaaag
ttgatgcatagtaacagcctgaacaactctaacattccccgatttggggtgaagactgat
caagaagagctcctggcccaagaactggagaacctgaacaagtggggcctgaacatcttt
tgcgtgtcagattatgctggaggccgctcgctcacctgcatcatgtacatgatattccag
gagcgggacctgctgaagaaattccgcatccctgtggacacgatggtgacatacatgctg
acactggaggatcactaccatgctgacgtagcctaccataacagcctgcacgctgccgac
gtactgcagtccacccacgtactgctggccacgcctgcgctagatgcagtgttcacggac
ctggagattctcgccgccctcttcgcggctgccatacacgatgtagatcaccctggggtc
tccaaccagttcctcatcaacaccaattcggagctggctctcatgtacaacgatgagtcg
gtgctcgagaatcaccacttggccgtgggcttcaagctgctgcaggaggacaactgcgac
atcttccagaacctcagcaagcgccagcggcagagcctacgcaagatggtcatcgacatg
gtgctggccacggacatgtccaagcacatgaccctcctggctgacctgaagaccatggtg
gagaccaagaaagtgaccagctcgggggtcctactgctggataactactccgaccgcatc
caggtcctccggaacatggtgcactgtgcagacctcagcaaccccaccaagccgctggag
ctttaccgccagtggacagaccgcatcatggccgagttcttccagcagggtgaccgtgag
cgcgagcgtggcatggaaatcagccccatgtgtgacaagcacactgcctccgtggagaag
tctcaggtgggttttattgactacattgtgcacccattgtgggagacctgggcagacctt
gtccacccagacgcccaggagatcctggacactttggaggacaaccgggactggtactac
agtgccatccggcagagcccgtcgccgccacctgaggaggagtcaagggggccaggtcac
ccacccccacctgataagttccagtttgagctgactctggaggaggaagaagaggaagaa
atatcaatggcctcgataccgtgcacagcccaagaggcattgacagcgcagggattgtca
ggagccgaggaagctctggatacaaccatggcccgggaggcatccccagcgcaggagtca
ttggatgttatggcacaggatgagtccctggaggccgagctggaggaagtgtatttgaca
cagcaggcacagtccacaggcggtgcacctgtggctcaggatgagttctcgtcccaggag
gaatccgtggttgctgtaagccagagcagcccctctgccctggctcttcaaagtcccctt
ctccctgcctggaggaccctgtctgtttcagagcatgccccgggcctcccgggcctcccc
tccacggcggccgaggtggaggcccaacgagagcaccaggctgccaagagggcttgcagt
gcctgcacagggacatctggggaggacacatctgcattcccagctcctggtgggggagag
tcaggtggagaccctacctga
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