Puntigrus tetrazona (Sumatra barb): 122350522 Help Entry 122350522         CDS       T08985                                  Symbol obscna Name (RefSeq) obscurin   KO K17531   obscurin-RhoGEF [EC:2.7.11.1] Organism ptet  Puntigrus tetrazona (Sumatra barb) Pathway ptet04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:ptet00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     122350522 (obscna)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:ptet01001]     122350522 (obscna)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:ptet04131]     122350522 (obscna) Enzymes [BR:ptet01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      122350522 (obscna) Protein kinases [BR:ptet01001]  Serine/threonine kinases: CAMK group   Trio family [OT]    122350522 (obscna) Membrane trafficking [BR:ptet04131]  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     122350522 (obscna) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  I-set Ig_3 ig Ig_2 V-set Pkinase PK_Tyr_Ser-Thr Ig_4 Izumo-Ig RhoGEF Ig_6 PH Kdo IQ IQ_SEC7_PH APH Motif Other DBs NCBI-GeneID:  122350522 NCBI-ProteinID:  XP_043103008 LinkDB All DBs Position 8:complement(9190061..9230102) Genome browser AA seq 6756 aa AA seqDB search MALNRIQLVKGLEDVTLCEKEASTFEVVLSHAYVQGQWSRDGVPLKSRPVCRIAMQGKKH TLTLTRVTVADMGVISFKAEGIESSAVLTVTARDIKIAKALQNVNVTEREDVTFICEVNW EDVDGKWYKDDNRLRAGDNVKIRCEGKIHSLTYKSVKPEDAGEIRFTAERVSSTATLQVK ELPVHIVKPLRVKIAMYKHRALLECLVSRPNAVVKWYRRNHEIVPNRKYQTISEGVYRQL IIDDVGSSDEDTFICDAVDDRTSCQLFVEEQAISILKGLSSVEVMEPKEARFKVETSIKL ERAPKWTLNGQILYPCPEVRIERQGTSNRLIFTQTDSSMCGTVQFTSGKSKSEAQLTITE RPLIVRQPISDVEVKENESVTLSCEFCPSPRVVRWFKGRNPLIASNKYAMKREKNRVEIT IMGVKAADSGEYRCLAGGSETSGRVSVEVKRLKIIRHLEQVEVEEDGTAVFSCELNHESP SVQWLLNDRVLYTNYINKIQNSGKVYSLILKRLAPQESRVTFKTFDISESAFLRVREKPA VFLRSLEDVAGEERGEILLHCDVSKPSVTPVWRKDGEILTANEKYDILHVGKSLTLKICM LRKDDGGEYSCDIGCSQTKAKVIVCDLRITIVKRIRTTTVLEGESCRFECVLSHEIIDEA SWILNGRLIVSNGRIIVANKGCKYTMSIQEVTISDAGEVVFTIKELSCRTMLFVKEKPVR VFRDMLNVKATPGEDPELSCEITKPDATVKWLKNGRLIRVSPKYEITQNNYLVKLIIHNA AIMDSGEYCCEADGTATRARLDVRDLQHTFAKELKDMRAEEKSMVTMECETRRPAATVTW LKGLMVLSSGQKYMMKKKDVVLTLTIFNLEKSDSAVYTCDVGTMQSRALLTIQGQKVVIV DELEDKECLEGDTIIFQCRICPSDYTDVKWYLDETLLYTNDLNEIKMIPGGYHTLIFKQL ARKDTGTISFEAGDKRSYASLLVRERRPTITKALEDTEAIEGGSLVLLCKTSKPCHIVWY KDGCLIWNSSKYLASRSGNEARLAIRDVKDSDAGVYECDAGSVITKATVTVKVIPAEFTK ALQNQEVKEGESSMLICEFSIPGVQFVWRKGPETLKSSEKYHMRQKKSCISLTIHNLKPE DSGNYICICRDQRTMATLTVNAVPISFIKELKNQETDEGKTVTLRCELSKAGIPVEWLKG EQTLLPGEKYQMRHIVTILELVIRSPVSEDSGTYICVCEDQRTKAIVKIRSQPITFKQKL RNQMGEEGNSIILHCEISKPDTPVQWRKGSNLLRSGEKYKIRQRGCMLELKIFNLTQEDN GVYSCMSETTETSANVTVSAQPVTFKEKLKNLVAEEGKMITLHCELSKTGIPVEWWNGED LLQPGEKYKMRERDTSVELIICEAMPEDSGVYRCVCGDQKTKATVKIVGAPATFKQNLKN KEALEGESITLHCELSKAGVPVEWWRGDKLLLPVPRYQMRLDGKTAELEITNVFPDDAGI YSCVTGGQKTTAEVKVKSLPITFKRELQNQISTEGESAVFTCELSKPGATVEWRKGRVML KSGAKYQMMLEGRLTKLLINNLVEGDAGNYTCKTKDSQSTAELTVQGLPATFKTTLKNQE TQEGNSVTVHCELSKAGVRVEWWKGEELLKTGEKYQLRQKEATVELLIRKAQPEDSGVYR CVCGDQNTEATIKVIALPITFKQELKNQEGEEGNNITLRCELSKASADVKWLKGEEVLKH GEKYQLRQIATKMELVIRKVIPEDSGVYFCVCPDQTSKATVKINALPITFKQNLRNQEAV EGNTVAFRCELSKPGAMVKWWRGEEVLQVGEKYQMRTEGRIAELLIKNINSEDVDFYSCT TGKEKTTAEVKVRALPVTFKRELQNEVTKEGGQAVFSCELSKPGAQIDWRKGRVILKPSD KYEMKQEGTFTKLVIRNVEASDAGNYSCKTKDSESTAELTVKVPPITFKVKLKNQEVEEE NKLVLHCELSKAGCPVEWRKGEELLRSGYKYQIREHDVTRELIIIKAMPEDSGVYSCICG EQKTKATIRVFATPVTFKQNLKNQDAPEGGVVILHCELSKAGVPVTWLKGDEELCNGTRH KIKQEGLVAELKIKNVLPVDVGEYSCIVGDQKTTAEVNVRAAASVYFEKELESQEAIEGD SVLFRCLLSSDNAPVTWRKDANQITQGGRYTLHRKGSTQELEIRKLRVQDAGMYSCNVRG KKTSATLRVIERVRIVKGLRDLTVTAGESAHFVCELSHENVLDGVWWLGSNELQENEMNQ MSICGREHHLVLTMTTTEESGVLSFVVGNEKTSARLCVNSKPTVFIEERLKDITIFEGDS ATLSCVTSDSCTPVTWKRNNVTLLSGEKYEPLKHGKRNVLLIHKVRKEDAGIYMCDTGDM QSSATLTVKERPLFFCRELQNQEAEEGETSFLCCELSQPGVAVEWKRGAVLLRPGNKYEI KQDGCELQLQINDLTSQDSGAYRCCADGIETRASITVKERPLFFHEELQNQEAEEGESAF LCCELSKPGVAVQWKKGAMLLKNGQKYEMTQEGNEVQLQIHDLTSQDSGTYRCCAGNIET RANIIVKEQPLFFCEELHNQEAEEGETAFLCCELSKPGVDMQWKKGAVRLRPGDKYEMKQ DGCKVQLQIHDLTRQDSGTYKCCSGSLVTTATIVVKEHPLYFIKMLECQEAEEGETAHLC CELSKPGAAVQWKKGSVLLKPGRKYEIKQNGSELQLQIHELSSQDSGVYTCCVGSLVTSA SLEVKEQPLYFCEELQRQEVEEGETVKLSCELSKPLVEVQWRKGTMLLRPGNKYEMKQDG CKLQLLIHELNSQDSGVYKCCAGSLVTTASIDVKESPVVFQEGLQSLEAKEGETATLTCE LSKPGVAVQWRKGTVLLKQGNKYEMKQDGCLHQLQIYDLKREDSGSYKCCAGTLMTTASL VVKEHPLFFSKELKNQEAEEGRTAIFCSELSKPGVLVQWKKGTVLLKPSKKYEIKQDGCQ LQLQIHELTAQDSGEYKCCAGNLVTTASFVVKEKPLFFSDELQNQEAQEGKTAILCCELS KPGVSVQWKKGTVLLKPSNKYEIKEVGCKQQLQIHNLTAQDSGDYKCCAGNLATAASLVI IEKPLFFSEELQNQDAEEGKTVTLHCKLSKPGISVQWKKGTVLLKPSKKYEISQNGQQIQ LQITEVTTQDSGAYKCCVGSLVTTASLVVKEHPLFFSDELQNQEAEEGKTVTLCCALSKP GVLVEWKKGTMLLKPSKKYEIKQDGCQLQLQIHGLTAQDTGDYKCCAGNLVTTASFLVKE KPLFFSDELQNQEAQEGKTAILCCELSKPGVSVQWKKGTVLLKPSEKYEIKQDGCQLQLR IHELTAQDSGAYKCCAGSLVTTCSVTVKEQPIFFCKNLQSLEAEESETVTLTCEISKPGV AVQWKKGTVLLKPGSKYGMKQDGYVLQLQIRDLKSDDSGSYKCCTGSIVTTASLLVKEHP LFFSKELQNQEAEEGKTVTLHCELSKPGVSVQWKKGAVILKPCKKYEIKQDGCQLQLQIH EVRVQDSGAYKCCAGSLATNVSVKVKEQPLFFCKKLQNIEAEEGETAFLTCELSKPGVAV QWKKGSVLLKPGNKYEMKQNCSELHLRINDLKCQDSGVYKCCFAMLETTASVVVKESEPK IKDIPQAPPRIKVKNIMEETLSSLVHKKQDAVIEESDISILEPTEVHFQDLSKKRTDDQE DKIKSLVRQRGKDVDPIMVIDEPSCTMGEPEIHSLATNVPKEQNIMGLDTSSKWVTKISV DQHNEEISWQVLTNTPSRTDRNEQSKKPPRDVPLPPPRSKGKATHTDDLLQDQHSVNEQT LYKRGKEQDAVIKATVETTKALKHVDLTVSLPKENISQLHVETKEQPYVLEAKIRDMDIK QTVVDTTLKIAEHGLNTPVFKEITTRHTESCQEQPSNLEENNQYIKLESTLNKEPLHTNK KKELKQKSLDKHAAHDNQNVQSEKSQSMDINYGQITKNIIEKAPSIAITNQNLKEQIHCT QDTTIPVRDVQKELQEGELNLPHFDSGEIKHVKQAVDIKVPKYEKLPKHVTGKAAHIAIT SQKVKEEVIAAEKTTAIKDVQKYSEEGELNLLHTDNEDMKNVKQALDEDKVKAPHHVKGK VTNISITQQKPKEQTKDTTMPVRDVQEELQANEPIVLHINSGELKHVRQDVEDHHSKVPK HVTGNATNIAIVSQFKEEIIPAEKCTTMYIRDVQRDSQEVESNLLHIDSRDEKNAKQVID EHNVKVPKHVKEKPTSIARHQLREEIIPAEKSIAISFRDVQKSSQEVQKDQKIVKEVVLK EDVSRRSSTQPEEVMPEEITSMDTDKQKSLKAEKRCPGTDTDFEDEPEMLEAAIKIQAAF KGYKTRKDMRLIFKEVFKNQNIDLGDAAFLECVVEGKISTVRWLKDGVDLKSGKRHKITH NAHGRCLLEISSFTNKDAGIYTCEVANKFGAISYNGNVMVGKPEKPSQTIETVQTPGAKM VSEKEILPTINTEEESLRLVYDLPADDTYSKIQEKRRSLISVSSISCYSDYDTAPDAETE YQSRGKEAEKKKEEKSSNVQSPKNSDQLKVKGGDSKSQTPSPKRMHSYKSSANAESFSES DGDDDRGETFDIYVAKSDCQPMGGNKEAFVLKEGQFVEVLDSAHPVRWLVRTKPTKNTQS RQGWVSPAYLEKKTREIFSLTHEAETKEASEKGKTVFTKDEHSLIQSRLIKGLLDGENNF VHEMNFFVEHHLQYLETSSQVPLTILSQKEYIFRNIRDIASFHECCILPKLEMCFSDDDV AQCFVTYALDFEMYLQFITGLSQAEACISDKNTQHFFKQYANTELAHLNTQVFNVSTYLQ RPMERIQTYKNVLKELIRNKAKSGQNCCLLEDAFAIVSSLPWRAENLHHLSMIENYPAPL KGLGEPIRQGHFTVWEEIPEVKISQRGHHRHIFLFKDCIVFCKPKRELGTYAEAYIFKNK MKLSDIDVKDTVEGDDRSFGLWHEHRGMVRKIILQARSILLRLSWLKDLRDLQQRSKQPT WTAPCFEQHLTDYPSRLGQTVKLVCKITGTPKPVIKWYKDGHAVKEDEHHITSEGQLGAC YLVVTSVTEADSGQYMCYATNPAGNASTLANIMIDVPPSFTTRLQNSVLVKGQDVQFKCS TQSAPLPSVRWFKDSIQLEDNRKHQIHSDVQTGNLILTIKRAEDADLGQYQCELQNEVGS AKCKAELCPPAPLPVTIRTQKQSQTTPTPELQSEGWSSSFVKNLFHILFQPGNPEPPAAG IEDTQTLKEQEDDERQVHAEKEEGPVEPEEHFYSDTEEELLTEPPAVHVAIEDLTVRPGQ PATFSAIITGQPTPDIQWFKDDKEILSNDYTEIFQSSARCSLTLLNTQVEDCGIYTCISS NSAGQASCFAKLSVDTGPDDIEEEREVEFGKRRKLHSVYDVHEEIGRGTFGVVKKVTHKA SGECFAAKFLPLRSSTRTRAFQERDLLSRLAHRRIACLLDFFATRRTLVLVVELCSTQGL LDHLFLKGSVSEREVKLYIQQVLEGIGYIHSMNILHLDIKTDNIMVSIVREDIKICDFGF CQEIDTSRHQYSKFGTPEFIAPEIVHQEPVTIATDIWSLGVVTYLCLTCHCPFFGENDRA TLMKVAEGLLYWDTPEITSRSVEAQDFLHRVLQPDPERRPSASECLSHEWFQGYYEDEEP ENINTTNLKSFILRRKWQRSLTCLGSVLTLRPIPELLEAPLRDVSITATRETQEPSSTSL SSGSSSEFDEADAWDFFQQVSQEDEDDLEDEEEDYNPYVHVSKTPTVLKRDEDDVLMGED HIHSGPLVIPTTAPSTEPVSLEKRDSSPYLYLSERDEGLDPIPRRSLIKSTFYCSSEQLS PMSARHMTLRDKIQAKKQERGRKPLRASLSGRLNEPLIEYVEDSPDLEANRNQRRGSMHS SILKSSSFDNGVSAAHPSIHTQRRSRSLDVYTQRSPASTEPTVQREDEHDAEESQNPDVT DEEEEKTEEVQVRRKLCRRSAFLSKKGPAVVRKVKAQVHKSEEGHQPASQSSYEDDNQLV ETETRHLGGEESVDGSQLSLACSLDHGSEASSRIGSHEELSHRHDHDGTLIAGSSGKISP CSLLQDSEDEDMERVLRSLRQDLPQAPPRRRTNSSSSGVNEMRNKSEVHLRRSSSAVPVQ AGVAGRESKEVLQRHASAPALEVKPPSGKSPKPGFMKIFRKHSWASHSSPQLEGSEKKQT DGASSQPKTPLLTLRKKMRASASSITKLFTRQSSKEDEEKKKSGPIMKNSSPVMPEKLTT VKAVSSSESPQKKSKLFSLKVPIFKKSKESPVKPSRPDVIHLAGGGALVFWKPMPSKELV TYCIQYSVNGVEWRILSENVTDSCFTANALPRGPGYMFRVSYNTKTGLAPFSEPSPPAFM ATPYEDSHNPLIEMESIGSKVTVPGGFGTEKSYSFLSEINRGRFSVIMQCEDSRSSQMLA SKMTPYRPEQRQLALREYQLLRRLNHPRIVQLQSAILTPTCLVLIEELCSGRELLYNLAE RNLYSETQVTDLLEQILSAVDYLHSRRIVHLDLKSDNMLVTGRNLVKIVDLGSAQPFTPG QALNIEHIKEMTDNKGYIVLPKAPEILEGQGVGPETDIWAVGVLAFIMLSADSPFHADIN WERDRNIKKGKIQFNRCYPGLSEGAINFMKNTLSNKAWARPTAAECLQNPWIQGDRPPSK QTDSVVYFSTDKLQAYLREREVKRDHVRTKVNLPFP NT seq 20271 nt NT seq  +upstreamnt  +downstreamnt atggcattgaatagaattcaattggtgaaagggctagaagatgtgacgctgtgtgagaaa gaagccagtacttttgaagtggttctcagtcatgcttacgtccagggtcaatggagcaga gatggagtcccacttaaatccaggcctgtgtgtcgaattgccatgcagggcaaaaaacac acactcacactcacgcgagtcacggttgctgacatgggtgtcatcagcttcaaggctgaa gggattgaaagctctgctgtgttgacagtcacagccagggatataaagattgcgaaggct cttcagaatgtcaatgtgactgagagggaggatgtgacatttatctgtgaggttaactgg gaagacgtggatgggaagtggtacaaggacgacaaccggttgagagctggggacaatgtt aaaataagatgtgaaggtaaaatacattcactaacctacaaatcagtcaaaccagaagat gctggtgagataagattcactgctgagagggtctcttcaacagcaacactacaagtgaaa gagcttccagttcatattgtaaagcccctgagagtgaagattgccatgtacaaacaccgt gccttgctcgagtgcctggtctctcgtcccaatgctgtggttaaatggtacagaagaaat catgaaattgtgccaaacaggaagtaccaaactattagtgaaggcgtgtaccgacagctt atcatagatgatgtgggatcctcagatgaagacacttttatttgtgatgctgttgatgat aggacttcctgccaactgtttgtagaggagcaggccatcagcattctgaaaggactcagt tctgtggaggtcatggagcctaaagaggctcgctttaaagtggaaaccagtattaagtta gagagagcaccgaaatggaccctaaatgggcagatactatatccatgtccagaagttagg attgagaggcaaggaacttcaaacagactaattttcactcaaactgacagtagtatgtgt ggcactgtgcagttcacctcagggaagagcaagtcagaagctcaactcacaattacagaa cgccctttgattgtcagacaacccatttctgatgtggaggtgaaggagaatgagtcagtt actctcagctgtgagttctgtccatcccccagagtggtgcgctggttcaaaggtagaaat cccctgattgcttccaataagtacgcgatgaagcgggaaaagaaccgggttgagatcacc atcatgggtgtgaaagcagcagattcaggagagtatcgctgtctggctggtggttcagag acaagcggaagggtcagtgtggaagtgaaaaggttaaagatcataagacatttagagcaa gtagaggtcgaggaggatggaactgcagtgttcagctgtgaactgaatcacgagtcaccc agtgtccagtggctgctcaatgatcgagtcctatacaccaactacatcaacaaaatccag aattctgggaaagtctacagtctgattctaaaacgattagctcctcaagagagccgtgta acattcaaaacatttgatatcagcgagtctgcgttcctcagggtcagagagaagccagca gtgtttctcaggtcactggaggatgtagcaggtgaggaacgtggtgaaatccttttgcat tgtgacgtttccaagccatcagtgacacctgtttggaggaaagatggtgaaattttgacc gccaatgagaagtacgatattctccatgtgggaaagtcattaactcttaaaatttgcatg ctgagaaaggacgacggaggggagtacagctgtgatattggctgcagccaaactaaagcc aaggtcatagtttgcgacctgcgcattaccattgttaaacgcatacggacaacaactgtc ctggaaggggaaagctgcaggtttgagtgtgtcctgtctcatgaaatcattgacgaagca tcatggattttgaatggccgactgattgtgagcaatggacggattatagtcgctaacaaa gggtgcaagtacacaatgagcattcaagaagttacgatatctgatgccggcgaagtggtc tttaccattaaagagctcagctgcaggactatgctgtttgtgaaagagaagcctgtgaga gtttttagggatatgctaaatgttaaagcaacacctggtgaagatccagagctcagctgt gagatcacaaaacctgatgcaacagtcaaatggctgaaaaatgggcggctaattagagtc agcccaaaatatgaaattacccaaaataattatctggtgaagctcatcatccataatgca gctataatggactcaggagagtactgctgtgaggcagatgggactgctacgagggcgaga ttagatgtcagagacttgcaacatacatttgcaaaggaactgaaggatatgcgtgcagag gaaaagagtatggttaccatggagtgtgaaaccaggaggcctgccgctaccgtgacctgg ttaaaaggcctaatggtgctcagctctggacagaagtacatgatgaagaaaaaagatgtt gtcctcacgctgaccattttcaatctggagaaaagtgacagtgctgtttacacctgtgac gttgggacaatgcagagcagggctttacttacaattcaaggtcaaaaagtagtcattgtg gatgaactagaagataaagagtgtctagaaggcgataccatcatctttcagtgtcggatc tgcccaagtgactacactgatgttaagtggtacctggatgagaccttgctctacactaat gatcttaacgagatcaagatgatacccggtggataccacactcttatcttcaaacagctg gcgcgtaaagacacaggcaccatttcttttgaggctggggacaaaagatcatatgcatca ctattagttagagagagacgccccacaataactaaagcattggaggacacagaagcaatt gaaggaggaagtttggtgctgttgtgcaagacttcaaagccatgtcatattgtttggtac aaagatggttgtttaatctggaattcctcaaagtacttagcgagtcgatcaggaaacgag gccagactggccatccgtgatgtgaaagacagtgatgcaggggtgtatgaatgcgatgca ggatctgtcatcaccaaagccactgtgactgttaaagttattcctgctgagtttacaaaa gcgcttcagaaccaggaggtcaaagaaggagagagttcaatgctgatatgtgaattctct atacctggtgtccagtttgtgtggcgcaaaggacccgagactctaaaatctagcgagaag taccacatgaggcagaaaaaatcttgcatttcactaacaatacacaatctgaagccagag gactcgggcaattacatatgcatttgcagagaccaaagaactatggctactcttacagtc aatgcggttcctatatcatttattaaagagctcaagaaccaagagacagatgaaggtaaa actgtgacattacgctgtgagctttctaaagctggaatcccagtggaatggttgaaaggt gaacaaactctcttgcctggggaaaagtatcaaatgaggcacatagtcaccatattagag ctggtaatcagaagtccagtttctgaggacagtggaacgtacatctgtgtgtgtgaggat caaaggacaaaagccattgtcaaaatacgatctcagcctatcacattcaaacagaagtta agaaatcagatgggtgaagagggaaatagtataatcttacactgcgagatatccaaacca gacacccctgtccagtggagaaaaggaagcaaccttctcaggtctggggagaagtacaaa atcaggcagaggggctgcatgctagagctgaagatttttaacttgacgcaagaggataat ggagtttatagctgtatgagtgaaacaactgagacatcagccaacgtcacagttagcgct caacctgtcacttttaaagagaagctgaaaaacctggtagctgaggaaggaaagatgata acactgcactgtgagctttccaaaaccggtatcccagtagagtggtggaatggagaggat ttgctccagcctggagagaagtataagatgagagaacgagacacatcagttgagctgatc atttgtgaagctatgcctgaggacagtggagtctacagatgtgtctgtggagatcaaaag accaaagctacagtcaaaattgttggtgctcctgctacttttaagcaaaatcttaagaat aaagaagctctggaaggcgaatctataacccttcactgtgagctttccaaagctggagta cctgtggaatggtggagaggagataaactcctccttccagtgccacggtaccagatgagg ctggatggaaagactgcagagctggaaataactaatgtttttcctgatgatgctgggata tacagctgtgtgactggaggccaaaagaccacagctgaagtgaaagtcaaatcccttcca attactttcaagcgagaacttcagaatcagatctctacagagggtgagagtgcagtattt acctgtgaactttcaaagcctggcgctacagtcgagtggaggaaaggtagagtcatgctg aaaagcggagccaaatatcagatgatgcttgaggggcgattaaccaaactgctgataaat aatcttgttgagggtgatgccggaaattacacctgcaaaaccaaagattcacagtcgaca gctgaattgacagttcaaggactcccagctacctttaaaacaactttgaagaaccaagaa actcaggaggggaacagtgtcactgtgcactgtgaactttctaaggctggagttcgagta gagtggtggaaaggagaagaactgcttaagactggagaaaaatatcagttgagacagaaa gaagcaacagtagagttgttaataaggaaggcacagccagaagacagtggagtgtatcgc tgcgtatgtggagatcaaaacactgaagccaccatcaaagttattgctctacccatcact ttcaaacaagaacttaagaatcaagaaggtgaagaagggaacaatatcacattgcgctgt gaactctctaaggccagtgctgatgtgaaatggttgaaaggagaggaggtcctaaagcat ggagaaaagtaccagttgagacagatagcaactaaaatggagcttgttatcagaaaagtc atacctgaagacagtggggtctacttttgcgtatgccctgatcagacatccaaagctaca gttaaaatcaatgctctcccgatcactttcaaacaaaacttgagaaatcaagaggcggta gaaggcaacacagtcgctttccgttgtgagctttccaaaccaggagccatggtaaaatgg tggaggggtgaagaggtgctacaagttggagaaaagtaccagatgagaactgagggacgg attgctgaacttctcatcaaaaatatcaactctgaagacgttgacttctacagctgcact actggaaaggaaaaaacaacagcggaggtcaaagttagggctttacctgtcacttttaaa cgagaacttcaaaacgaagtaaccaaagaaggtggacaagctgtttttagctgtgagctc tctaaacctggtgctcaaatcgactggagaaaaggaagagttattctcaagcctagtgac aaatatgaaatgaagcaagagggcacattcaccaaattggtcatacgtaatgttgaagca agtgatgctgggaactattcatgtaaaaccaaggattctgagtcaactgctgagctaacc gtgaaggttccacctatcacttttaaagtcaagttgaaaaatcaggaagttgaagaagaa aataaacttgtgttgcactgtgagctctcaaaagctggatgtcctgttgaatggaggaag ggggaagagcttcttagatcagggtataaatatcaaatccgagaacatgatgttacaagg gagctgatcattataaaggctatgcctgaagatagtggagtctacagctgcatttgtggg gagcagaagaccaaagccacgatccgagtattcgccacaccagtaacgttcaaacaaaac ctgaagaaccaagacgcccctgaaggaggtgttgttattctgcattgtgagctgtccaaa gctggggtaccagtaacatggttaaaaggggacgaggagctctgcaatggaactagacac aagatcaagcaggagggactggttgcagaattaaagattaaaaacgttcttcctgtggat gttggggaatacagctgtattgttggagaccagaagactacagctgaagttaatgttagg gctgctgcctctgtttactttgagaaagagcttgagagtcaagaagcaatagagggggat tctgtcctgttccgttgtttgctctctagtgataatgccccagtgacttggagaaaagat gcaaatcagatcacacagggtggccgttatacccttcaccgtaaaggttcaactcaggag cttgaaatcaggaaactgagagtgcaggatgctggcatgtactcatgcaacgtcagaggc aagaagacctctgcaaccctcagagtgatagagcgtgtgagaattgtgaaaggactgcgt gacctgacagttactgcaggcgagagcgcacattttgtgtgcgagctttcacatgagaat 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aacaagtatgagatgaaacaagatggttgtctacatcagcttcaaatatatgacctaaaa cgtgaagatagtggctcatataaatgctgtgctggcactctcatgacaactgcttcactt gtggtaaaggaacatcctttgttcttttccaaggaactcaaaaaccaagaagcagaagag ggtaggacagcaatattttgctctgagctctctaaacctggagttttagtgcagtggaag aagggaactgtgttgctgaagcctagtaaaaaatatgagataaaacaggatggctgccaa ctacagcttcagatccatgagcttacagctcaggacagtggggaatataaatgttgtgct ggaaacctggtcacaactgcttcatttgtggtaaaagaaaagccattgtttttctctgat gagctccaaaaccaagaagcacaggagggtaagacagccatattgtgctgtgagctttct aaacctggagtttcagtgcagtggaagaagggaacagtgcttttaaagcctagcaacaaa tatgagattaaagaggttggctgcaaacaacagcttcagatccacaatctaacagctcag gacagcggggattacaaatgttgtgctggaaacttggccacagctgcttctcttgtaata atagaaaagccattgttcttctcagaggagctccaaaaccaagatgcagaagagggtaag acagttacattgcactgtaagctctctaaaccaggaatttcagtgcagtggaaaaaagga acagtgcttttaaagcctagtaaaaaatatgaaattagtcagaatggccagcagatacag cttcagatcactgaagttacaactcaggacagtggggcctacaaatgctgtgttgggagc cttgtcacaacagcatctcttgtggtgaaagaacatcccttgttcttctctgatgagctc caaaaccaagaagcagaagagggtaagacagtcacattatgctgtgcactctctaaacct ggagttttagtggaatggaagaaggggacaatgcttttaaaacctagtaaaaaatatgag ataaaacaggatggctgccaactacagcttcagatccatgggctaacagctcaggacact ggggattacaaatgttgtgctggaaacctggtcacaactgcttcttttttggtgaaagaa aagccattgttcttttctgatgaactccaaaatcaagaagcgcaggagggtaagacagcc atattgtgctgtgagctttctaaacctggagtttcagtgcagtggaagaaggggacagtg cttttgaaacctagtgaaaaatatgagataaaacaggatggctgtcagctacagcttcgt atccatgagctaacagctcaagacagtggggcctacaaatgttgtgctggaagccttgtc actacttgctctgttacagtgaaagagcaaccaatattcttctgtaagaacctccaaagc cttgaagcagaagaaagtgagactgtcaccctgacctgtgagatctctaaacctggagtt gctgtgcagtggaagaagggaacagtgctgctaaaacctggaagcaagtatggaatgaaa caagatggctatgtgctacagctccagatacgtgatcttaaaagtgatgatagtgggtct tataaatgttgtactggtagtattgtgacaacagcttctcttctggtaaaggaacatcct ttgttcttctctaaggagctccaaaaccaagaagcagaggagggtaagacagtcacattg cactgtgagctctctaaacctggagtttctgtgcaatggaagaagggagcagtaatactt aaaccttgtaaaaaatatgagattaaacaggatggctgccaactacagctccaaatccat 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gtctctgagaaagagattttgccaacaattaacacagaagaggagtcattaagacttgtc tatgacctaccggcagatgatacctacagcaagatccaggagaaaaggagaagtctaatt tcagtcagctctatatcgtgttactcagattatgacacagccccagatgctgagacagaa taccaatctagaggtaaagaggcagagaagaaaaaagaagaaaaaagtagtaatgtgcaa tccccaaaaaattcagaccagctaaaagtgaaaggtggcgattcaaagagccagacccct tcacccaaacgcatgcattcctacaagtcctctgcaaatgctgagtcgttctctgagtca gatggagatgatgatagaggagagaccttcgatatttatgtagccaaaagtgattgccaa cctatgggaggaaacaaagaggctttcgtactaaaggaaggacagtttgtggaggtcctg gactcagcccatcctgtgagatggcttgtccgtacaaagccaaccaagaacacacaatct cgtcaaggctgggtatccccggcgtacctagaaaagaagacaagggaaatattttcattg acccatgaagcagagacaaaagaggcctctgagaaaggcaaaacagttttcacgaaggat gagcacagtttgatccaaagtcgcttgattaagggactccttgatggtgaaaacaatttt gtgcacgagatgaacttctttgtggagcaccatttacaatacttggagacaagctctcaa gttcctctcaccatcctaagtcaaaaagagtacatatttcgcaatatcagagatattgca agtttccatgaatgttgtattctccctaagctggagatgtgtttctcagatgatgatgta gcccagtgttttgtcacttatgcactggactttgagatgtatctccagttcattacaggc 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agccaggaggatgaagatgatctagaagatgaggaagaggactataacccatacgtccac gtatcaaagacgcccacagttcttaaacgggatgaagatgatgtgcttatgggtgaggac cacattcacagcggcccgctagtgattcccacaactgcaccatcaacagagccagtcagt ttggagaagagggacagtagcccctatctttatctttctgagagagatgaaggattggat cccataccacgccgtagcctcatcaagagcactttttattgcagctctgagcagctctca cccatgtctgctcgtcacatgacgcttcgagataaaatccaagctaaaaagcaagagcgt ggtcgtaaaccccttcgtgccagcctctctggcaggttaaatgagcccctcatagagtat gtagaagattccccagacttagaagctaatcgtaaccaaagaagaggatcaatgcattct tctatcctcaagtcaagctcttttgataatggagtgagtgctgctcatccaagcatacac acccagagaagaagcagatcattagatgtatacacacaacgctctccagcttcaactgag ccaacagtgcaaagagaggatgagcatgatgctgaagaaagccagaatccagatgtcact gatgaagaagaggagaaaactgaagaagtccaagtgagaaggaaactttgccgtcgctct gcgtttttgtcaaagaagggcccagccgttgtgagaaaggtcaaagcacaggttcataag tctgaagaaggacatcagccagcctcgcaaagttcttatgaggatgacaaccagttggtt gaaacagagacaagacatttaggaggtgaggagagcgtggacggctcacagctttcacta gcatgttcgcttgatcacggttcagaggcttcgagcaggataggctcacatgaagaactc tcccacagacacgaccatgatgggaccttgatcgctggatcttctggaaaaatatcccca tgctctttactacaagactctgaagatgaagacatggagagggtcctgagatctcttcgc caagacctcccgcaagccccaccaagacggcgcaccaacagttcaagctctggagtaaat gagatgcgcaataagagtgaagtccatctgagaagaagctcctctgcggttcctgtccag gctggagtagcgggacgagaaagcaaagaggtgcttcaaagacatgcctccgccccagct cttgaagtcaaaccacctagtgggaaatcgcccaagcctggattcatgaagatcttccgt aaacattcgtgggctagccattcttctcctcaactagaaggctcagaaaagaaacaaact gatggagcatcctcacaacccaagacccctcttctaaccctgaggaagaagatgcgagca tcagcctctagcattacaaaactgtttacccgacagtccagtaaagaggatgaagagaag aagaaaagcggaccaattatgaagaactcctcccctgtcatgccagagaaattgaccaca gtgaaagctgtcagctcatctgaaagtccacagaaaaagtccaaattgttctcactaaaa gtgccaatatttaagaaatcaaaagaaagtccagttaaaccatccaggcctgatgtcatt cacctagctggtggaggagcgcttgtgttctggaaacctatgccatccaaagaacttgtt acatattgtattcagtatagtgtaaatggtgtggagtggagaatattgtcagagaatgtt acagacagctgctttacagcaaatgcccttccgagaggaccaggatatatgttcagagtg tcctataataccaagacagggttggcacctttcagcgaaccttcacctccagcctttatg gccacaccttacgaagactctcacaatcctctcattgaaatggaatctattgggtcaaag gtcactgtacccggaggttttggcactgagaaatcctacagcttcttatctgaaatcaac agaggccgtttcagtgtgataatgcagtgtgaggacagccgcagctctcagatgttggcc tcaaagatgacaccctacagaccagagcagaggcagttggctttaagggaatatcagctg cttcgccgactaaaccaccctcgaatcgtccagctgcagtcagccatcctgacccccacc tgcctggtgcttatagaagaactctgctcaggacgagagcttctttataaccttgcagaa aggaatctatattcagaaacacaggtgactgacctgctagagcagatcctgagcgctgtg gattaccttcacagcagacgcattgtacatttggacctgaagtcagacaacatgcttgtg acgggccgaaatttagtgaagattgtagatttgggctctgctcagcccttcactccagga caggctctaaacattgaacacatcaaagaaatgacagataataaaggttatattgtcctt cctaaagctcctgaaatcttagaaggacaaggagttggacctgaaactgatatctgggct gttggtgttttggcttttataatgttgagtgcagacagtcccttccatgctgacataaat tgggaaagggaccgaaacatcaaaaaaggaaagattcaatttaatcgttgttacccggga ctctcagagggagccattaactttatgaagaacaccctgagcaacaaagcctgggcaaga ccgacagctgcagagtgcctccaaaacccttggatacaaggagaccgtcctccctctaaa caaactgactctgtggtctacttctcaacagataagctgcaggcctatctcagggaaaga gaggtcaaacgagaccacgtccgcacaaaagttaatctgcccttcccataa

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