Panthera tigris altaica (Amur tiger): 102954149 Help Entry 102954149         CDS       T02988                                  Symbol ACACA Name (RefSeq) acetyl-CoA carboxylase alpha   KO K11262   acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15] Organism ptg  Panthera tigris altaica (Amur tiger) Pathway ptg00061   Fatty acid biosynthesis ptg00620   Pyruvate metabolism ptg00640   Propanoate metabolism ptg01100   Metabolic pathways ptg01212   Fatty acid metabolism ptg04152   AMPK signaling pathway ptg04910   Insulin signaling pathway ptg04922   Glucagon signaling pathway ptg04936   Alcoholic liver disease Module ptg_M00082   Fatty acid biosynthesis, initiation Brite KEGG Orthology (KO) [BR:ptg00001]  09100 Metabolism   09101 Carbohydrate metabolism    00620 Pyruvate metabolism     102954149 (ACACA)    00640 Propanoate metabolism     102954149 (ACACA)   09103 Lipid metabolism    00061 Fatty acid biosynthesis     102954149 (ACACA)   09110 Biosynthesis of other secondary metabolites    00254 Aflatoxin biosynthesis     102954149 (ACACA)  09130 Environmental Information Processing   09132 Signal transduction    04152 AMPK signaling pathway     102954149 (ACACA)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     102954149 (ACACA)    04922 Glucagon signaling pathway     102954149 (ACACA)  09160 Human Diseases   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     102954149 (ACACA) Enzymes [BR:ptg01000]  2. Transferases   2.1  Transferring one-carbon groups    2.1.3  Carboxy- and carbamoyltransferases     2.1.3.15  acetyl-CoA carboxytransferase      102954149 (ACACA)  6. Ligases   6.3  Forming carbon-nitrogen bonds    6.3.4  Other carbon-nitrogen ligases     6.3.4.14  biotin carboxylase      102954149 (ACACA)   6.4  Forming carbon-carbon bonds    6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)     6.4.1.2  acetyl-CoA carboxylase      102954149 (ACACA) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  ACC_central Carboxyl_trans CPSase_L_D2 ACCA_BT Biotin_carb_N Biotin_carb_C Biotin_lipoyl ATP-grasp Dala_Dala_lig_C ATP-grasp_3 MetallophosN Motif Other DBs NCBI-GeneID:  102954149 NCBI-ProteinID:  XP_007096078 LinkDB All DBs Position Un AA seq 2396 aa AA seqDB search MLRIRSTCVESRLSRRVRCGVQSFCCSRCVFVSWWEPGPALRAHFEGIMDEPSPLAKPLE LNQHSRFIIGSVSEDNSEDEISNLVKLDLLEEKEGSLSPASVGSDTLSDLGISSLQDGLA LHMRSSMSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEKVLIANNGIAAVK CMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVEL ILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWALGDKIASSIVAQT AGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYQKGYVKDVDDGLKAAEEVGYPVMIKA SEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAIS LFGRDCSVQRRHQKIIEEAPAAIATPAVFEHMEQCAVKLAKMVGYVSAGTVEYLYSQDGS FYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMYGVSPWGDAPIDF ENSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEF ADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFQLNRIDTGW LDRLIAEKVQAERPDTMLGVVCGALHVADVSLRNSISNFLHSLERGQVLPAHTLLNTVDV ELIYEGVKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVD RYRITIGNKTCVFEKENDPSVMRSPSAGKLIQYIVEDGGHVFAGQCYAEIEVMKMVMTLT AAESGCIHYVKRPGAALDPGCVIAKMQLDNPSKVQQAELHTGSLPRIQSTALRGEKLHRV FHYVLDNLVNVMNGYCLPDPFFSSRVKDWVERLMKTLRDPSLPLLELQDIMTSVSGRIPP NVEKSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREVFFMNTQSIVQLV QRYRSGIRGHMKAVVMDLLRQYLRVETQFQNGHYDKCVFALREENKSDMNTVLNYIFSHA QVTKKNLLVTMLIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPS YELRHNQVESIFLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEV YVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLNRMSFSSNLNHYGMT HVASVSDVLLDNSFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFCDSPPQSPTFPEAGHT SLYDEDKLQVPRDEPIHILNVAIKTDCDIEDDRLAAMFREFTQQNKATLVEHGIRRLTFL VAQKDFRKQVNYEVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRNFD LTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLQNEGERLL LEAMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQ AELKINIRLTPTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPLHG MLINTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTQAFLPSPPLPSD MLTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMTLKSPEYPEGRDIIVIGNDITYLIGS FGPQEDLLFLRASELARAEGIPRIFVAANSGARIGLAEEIRHMFHVAWVDPEDPYKGYKY LYLTPQDYKRVSALNSVHCEHVEDEGESRYKITDIIGKEEGLGAENLRGSGMIAGESSLA YNEIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGREVYTSNNQLG GIQIMHNNGVTHSIVCDDFEGVFTVLHWLSYMPKNVHSLVPLLNSKDPIDRIIEFVPTKA PYDPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGGIPVGVVAVET RTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGLPLMVFANWRGFS GGMKDMYDQVLKFGAYIVDSLRECSQPVLVYIPPQAELRGGSWVVIDPTINPRHMEMYAD RESRGSVLEPEGTVEIKFRRKDLVKTMRRVDPVYIRLAERLGTPELSAAERKELENKLKE REEFLIPIYHQVAVQFADLHDTPGRMQEKGVINDILDWKTSRTFFYWRLRRLLLEDLVKK KIHNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQLTEEDGVRSVIEE NIKYISRDYVLKQIRSLVQANPEVAMDSIVHMTQHISPTQRAEVVRILSTMDSPST NT seq 7191 nt NT seq  +upstreamnt  +downstreamnt atgttgaggattaggtccacttgcgttgaaagtcgtctttctcgcagagtgaggtgtggg gtgcagagcttctgttgctctcgctgtgtctttgtatcgtggtgggagccggggccagct ctgagagctcattttgaaggaataatggatgaaccatcccccttggccaaacctctggag ctgaaccagcactctcggttcataattggttctgtatctgaagataactcagaggatgaa atcagcaacctggtgaagctggacctactggaggagaaggaaggctctctgtcaccagct tctgttggctcagatacgctctctgatttggggatttccagcctacaggatggcttggcc ttgcacatgaggtccagcatgtctggcttgcatctagtaaagcaaggtcgagaccgaaag aaaatagactcacagcgagatttcactgtagcttcaccagcagaatttgttacgcgtttt ggggggaataaagtgattgagaaggttcttattgccaacaatggcatcgcagcagtgaaa tgcatgcggtccatccgccgatggtcttatgagatgtttcgaaatgaacgtgcaatccga tttgttgttatggtcacacctgaagacctgaaagccaatgcagaatacattaagatggca gatcactatgtgccggtgccaggaggaccaaacaacaacaactatgcaaacgtggaatta attcttgatattgctaaaaggatcccagtgcaagcagtgtgggctggctggggtcatgct tctgagaatcccaagctcccagaacttcttttgaaaaatggcatcgccttcatgggtcct ccaagccaggccatgtgggctttgggggataagattgcatcttccatagtggctcaaact gctggtatcccaactcttccctggagtgggagtggtcttcgtgtggactggcaggaaaat gatttttcaaaacgtatcttaaatgttccccaggaattatatcaaaaaggttatgtgaag gatgtggatgatgggctgaaggcagcagaggaagttggatatccagtaatgatcaaggcc tcagaaggaggaggagggaaaggaatcagaaaagttaacaatgcagatgacttcccgaat ctcttcagacaggttcaagctgaagtccctggatctcctatatttgtgatgagactagcc aaacaatcccgtcatctggaggtacagattttagcagatcagtatggcaatgctatctct ctgtttggtcgtgactgctctgtgcagcgcaggcatcagaagattattgaagaagcacca gctgctattgctactccagcagtattcgaacatatggaacagtgtgcggtgaaacttgcc aaaatggttggttatgtgagtgcagggactgtcgaatacctctacagccaggatggaagc ttctactttctggaactgaaccctcggctacaggtggagcacccttgtacagagatggtg gctgatgtcaacctccctgcagcgcaactccagattgccatggggatccctctgtataga atcaaggatattcgtatgatgtatggagtatctccctggggtgatgctcccattgatttt gaaaattctgctcatgttccttgcccaaggggccatgttattgctgctcggatcactagt gaaaatccagatgagggttttaagcccagctcaggaacagttcaggaactgaatttccgt agcaataagaatgtttggggttatttcagtgttgctgctgcagggggccttcacgaattt gctgattctcagtttggtcactgcttctcctggggagaaaacagagaggaagcaatttca aacatggtggtggctttgaaggaactatctattcggggtgactttcgaactacagttgaa tacctcatcaaattgctggagactgagagttttcagctgaatagaattgacactggctgg ctagacagactgatagcagaaaaagtacaggcagagcgacctgataccatgttgggagtt gtgtgtggggctctccacgtggcagatgtgagcctacggaatagcatctctaacttcctt cattccttagaaaggggtcaagttcttcctgctcatacgcttctgaatacagtagatgtt gaacttatctatgagggagtcaaatatgtacttaaggtgactcgacagtcccccaactcg tatgtggtgatcatgaacggctcatgcgtagaagtagatgtgcatcggctgagtgatgga gggctgctcctgtcctatgatggcagcagttataccacatacatgaaggaggaagtggat agatatcgtatcacaattggcaataagacctgtgtgtttgagaaggaaaatgacccttca gtgatgcgctcaccttctgctgggaagttaatccagtatattgtggaggatggaggccat gtgtttgctggccagtgctatgctgagattgaggtgatgaagatggtaatgaccttaaca gcagcagagtctggctgtatccattatgtcaaacggcctggagcagctcttgaccctggc tgtgtgatagccaaaatgcagttagacaaccccagcaaggtccaacaggctgagcttcac acgggtagtctgccacggatccagagcacagcactgagaggcgagaagctccatcgagtg ttccattatgtcctggataatctggtcaacgtaatgaatggatactgccttccagatcct ttttttagtagcagggtaaaagactgggtagagcggttgatgaagaccctcagagatccc tccttgcctctcctagaattgcaagatatcatgaccagtgtctctggccgtattccccca aatgtggagaagtctatcaagaaggaaatggctcagtatgccagcaacatcacatcagtc ctctgtcagtttcccagccagcagattgccaacatcctagatagccatgcagctacattg aaccggaaatctgaacgggaagttttcttcatgaacactcagagcattgtccagctggta cagaggtaccgaagtggcatccgaggccacatgaaggctgttgtgatggatctgctacgg cagtacctgcgagtagagacacagttccagaatggtcactatgacaaatgtgtgtttgcc cttcgagaagagaacaagagtgacatgaacactgtgctaaactatatcttctctcatgct caagtcaccaagaagaatcttctggtcacaatgcttattgatcagttgtgtggtcgggac cctactctcactgatgagctgctgaatattctcacagagctaactcaactcagtaagacc accaatgccaaagtggcacttcgagcacgccaggttcttattgcctcccatttgccatca tatgagcttcgccataaccaagtagagtctatcttcctttcagctattgacatgtatgga catcagttttgcattgagaacctgcagaaactcatcttgtctgaaacatctatttttgat gtcctaccaaacttcttctatcacagcaaccaggtagtgaggatggcagctctggaggtt tatgttcgaagggcttacattgcctatgaacttaacagcgtccaacatcgccagcttaag gacaatacctgcgtggtggaattccagttcatgctgcccacatcgcatccaaacagaggg aacatccccacgctaaacagaatgtccttctcctccaacctcaaccactatggcatgact cacgtagctagtgtcagcgatgtgctgttggacaactcattcactccaccatgtcagcgg atgggcggaatggtctcttttcggacttttgaagattttgtcaggatctttgatgaagtg atgggctgcttctgtgactccccaccccaaagccccacgttccctgaggcaggtcacaca tctctgtatgatgaagacaagttacaggtccccagggatgaaccaattcacattctgaat gtggctatcaagactgactgtgatattgaggatgacagactggcagctatgttcagagag tttacccaacaaaataaagctaccctggttgagcatgggatacggcgccttactttcctg gtcgcacaaaaggatttcagaaaacaggtcaactatgaggtggatcagagatttcataga gaatttcctaaatttttcacgttccgagcaagggataagtttgaggaggatcgtatctat cgtcacctggagcctgctctagctttccagttagaactgaaccggatgagaaattttgac cttactgccattccatgtgctaatcataagatgcacctgtatcttggggcagccaaggtg gaagtgggcactgaagtgacagactataggttctttgttcgtgcaatcatcagacattct gatctggtcaccaaggaagcttcttttgaatatctacaaaatgaaggggagcggctgctc ctggaagccatggatgaattggaagttgcttttaataatacaaatgttcgcactgactgc aaccacatcttcctcaactttgtgcccacagtcattatggacccatcaaagattgaggaa tctgtgcggagcatggtaatgcgctatggaagtcggctgtggaaattacgtgtcctccag gcagaactgaaaatcaacattcgcctgacaccaactggaaaagcaattcccatccgcctc ttcctgacaaatgagtccggctattacttggacatcagcttgtacaaggaagtgactgac tccaggacagcacagatcatgtttcaggcatatggagacaaacagggaccattgcatgga atgttaatcaacactccatatgtcaccaaagacctacttcaatcaaagagattccaggca caatccttggggacaacatacatatatgatatcccagagatgtttcggcagtctctgatc aaactctgggagtctatgtccactcaagcattccttccatcaccccccctgccttctgac atgctgacatatactgagcttgtgttggatgatcagggtcagctggtccacatgaacagg cttccaggaggaaatgagattggcatggtagcttggaaaatgacccttaaaagtcctgaa tatccagaaggccgagatatcattgttattggcaatgacatcacatacctaattgggtcc tttgggccccaggaggatttgctgtttctcagagcttctgagcttgccagggcagagggt atcccacgcatctttgtagcagccaacagcggagcacgaattggactggcagaggaaatt cgtcatatgtttcacgtggcctgggtagatcctgaggatccttacaagggatacaaatac ttgtatctgacccctcaggattataagagggtcagtgctctcaactctgtccactgtgaa catgtagaagatgaaggagaatccaggtacaagataactgatattattgggaaggaagag ggacttggagcagagaaccttcgaggctctggaatgattgctggagaatcctcattggcc tataatgagattatcaccatcagcttggttacatgccgggctattgggattggagcttac cttgtccggctgggacagagaaccatccaggttgaaaattctcacttaattctgaccgga gctggagctctcaacaaagtccttgggcgggaagtatacacctccaataaccagcttggg ggcatccagatcatgcacaacaatggggtgacccacagcatcgtttgtgatgactttgaa ggggttttcactgtcctacactggctgtcttacatgcctaagaatgtgcacagtttagta cctctcctgaactccaaggatcctatagatagaatcatcgaatttgttcctacgaaggcc ccctatgatcctcgatggatgctagcaggccgtcctcacccaacccagaaaggtcagtgg ttgagtggattctttgactatggatctttctctgaaatcatgcaaccctgggcacagact gtggtggttggcagagccaggctaggaggaatacctgtaggagtagttgctgtagaaacc cgaacagtggaactaagtatcccagccgaccctgcaaacctggattctgaagccaagata atccagcaggctggccaggtttggtttccagattctgcgtttaagacctatcaggctatc aaggacttcaaccgcgaagggctgcctctgatggtctttgccaactggagaggcttctcc ggtgggatgaaagatatgtacgaccaggtgctgaagtttggtgcttacatcgtggatagc ttacgggagtgctcccagcctgtgctggtttacattcctcctcaagctgagctccggggt ggctcctgggttgtgattgaccccaccatcaacccccggcacatggagatgtatgctgac cgagaaagcaggggatcagttctggagccagaagggacagtagaaatcaaattccgcaga aaagatctggtgaaaaccatgcgtcgggtggacccagtctacattcgcttggctgaacga ttgggcaccccagagctaagcgcagctgagcggaaggagctggagaacaagttgaaggag cgggaggaattcctaattcccatttaccatcaggtagccgtgcagtttgctgacttgcac gacacaccaggccggatgcaggagaagggtgttattaacgacatcctggattggaaaaca tcccgtaccttcttctactggcggctgaggcgtctcctgctggaggacctggtcaaaaag aaaatccacaatgccaacccagagctcactgacggtcagatccaggccatgttaaggcgc tggtttgtagaagtggaaggaaccgtgaaggcctatgtttgggacaataacaaggatcta gtggaatggctggagaaacagctgaccgaggaagatggtgttcgctcagtaatagaggaa aacataaaatacatcagcagagactatgtcctcaagcagatccgcagcttggtacaggcc aatcccgaggttgccatggattccatcgtccatatgacccagcacatctcacccactcag cgagcagaagtcgtacggatcctctccacgatggactccccttcaacatag

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