Panthera tigris altaica (Amur tiger): 102961712 Help Entry 102961712         CDS       T02988                                  Symbol ADCY1 Name (RefSeq) adenylate cyclase 1   KO K08041   adenylate cyclase 1 [EC:4.6.1.1] Organism ptg  Panthera tigris altaica (Amur tiger) Pathway ptg00230   Purine metabolism ptg01100   Metabolic pathways ptg01522   Endocrine resistance ptg04015   Rap1 signaling pathway ptg04020   Calcium signaling pathway ptg04022   cGMP-PKG signaling pathway ptg04024   cAMP signaling pathway ptg04062   Chemokine signaling pathway ptg04072   Phospholipase D signaling pathway ptg04114   Oocyte meiosis ptg04211   Longevity regulating pathway ptg04213   Longevity regulating pathway - multiple species ptg04261   Adrenergic signaling in cardiomyocytes ptg04270   Vascular smooth muscle contraction ptg04371   Apelin signaling pathway ptg04540   Gap junction ptg04611   Platelet activation ptg04713   Circadian entrainment ptg04714   Thermogenesis ptg04720   Long-term potentiation ptg04723   Retrograde endocannabinoid signaling ptg04724   Glutamatergic synapse ptg04725   Cholinergic synapse ptg04727   GABAergic synapse ptg04750   Inflammatory mediator regulation of TRP channels ptg04911   Insulin secretion ptg04912   GnRH signaling pathway ptg04913   Ovarian steroidogenesis ptg04914   Progesterone-mediated oocyte maturation ptg04915   Estrogen signaling pathway ptg04916   Melanogenesis ptg04918   Thyroid hormone synthesis ptg04921   Oxytocin signaling pathway ptg04923   Regulation of lipolysis in adipocytes ptg04925   Aldosterone synthesis and secretion ptg04926   Relaxin signaling pathway ptg04927   Cortisol synthesis and secretion ptg04928   Parathyroid hormone synthesis, secretion and action ptg04934   Cushing syndrome ptg04935   Growth hormone synthesis, secretion and action ptg04970   Salivary secretion ptg04971   Gastric acid secretion ptg04972   Pancreatic secretion ptg04976   Bile secretion ptg05032   Morphine addiction ptg05142   Chagas disease ptg05146   Amoebiasis ptg05163   Human cytomegalovirus infection ptg05166   Human T-cell leukemia virus 1 infection ptg05200   Pathways in cancer ptg05207   Chemical carcinogenesis - receptor activation ptg05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ptg00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102961712 (ADCY1)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102961712 (ADCY1)    04371 Apelin signaling pathway     102961712 (ADCY1)    04020 Calcium signaling pathway     102961712 (ADCY1)    04072 Phospholipase D signaling pathway     102961712 (ADCY1)    04024 cAMP signaling pathway     102961712 (ADCY1)    04022 cGMP-PKG signaling pathway     102961712 (ADCY1)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102961712 (ADCY1)   09144 Cellular community - eukaryotes    04540 Gap junction     102961712 (ADCY1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102961712 (ADCY1)    04062 Chemokine signaling pathway     102961712 (ADCY1)   09152 Endocrine system    04911 Insulin secretion     102961712 (ADCY1)    04923 Regulation of lipolysis in adipocytes     102961712 (ADCY1)    04912 GnRH signaling pathway     102961712 (ADCY1)    04913 Ovarian steroidogenesis     102961712 (ADCY1)    04915 Estrogen signaling pathway     102961712 (ADCY1)    04914 Progesterone-mediated oocyte maturation     102961712 (ADCY1)    04921 Oxytocin signaling pathway     102961712 (ADCY1)    04926 Relaxin signaling pathway     102961712 (ADCY1)    04935 Growth hormone synthesis, secretion and action     102961712 (ADCY1)    04918 Thyroid hormone synthesis     102961712 (ADCY1)    04928 Parathyroid hormone synthesis, secretion and action     102961712 (ADCY1)    04916 Melanogenesis     102961712 (ADCY1)    04925 Aldosterone synthesis and secretion     102961712 (ADCY1)    04927 Cortisol synthesis and secretion     102961712 (ADCY1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102961712 (ADCY1)    04270 Vascular smooth muscle contraction     102961712 (ADCY1)   09154 Digestive system    04970 Salivary secretion     102961712 (ADCY1)    04971 Gastric acid secretion     102961712 (ADCY1)    04972 Pancreatic secretion     102961712 (ADCY1)    04976 Bile secretion     102961712 (ADCY1)   09156 Nervous system    04724 Glutamatergic synapse     102961712 (ADCY1)    04727 GABAergic synapse     102961712 (ADCY1)    04725 Cholinergic synapse     102961712 (ADCY1)    04720 Long-term potentiation     102961712 (ADCY1)    04723 Retrograde endocannabinoid signaling     102961712 (ADCY1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     102961712 (ADCY1)   09149 Aging    04211 Longevity regulating pathway     102961712 (ADCY1)    04213 Longevity regulating pathway - multiple species     102961712 (ADCY1)   09159 Environmental adaptation    04713 Circadian entrainment     102961712 (ADCY1)    04714 Thermogenesis     102961712 (ADCY1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102961712 (ADCY1)    05207 Chemical carcinogenesis - receptor activation     102961712 (ADCY1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102961712 (ADCY1)    05163 Human cytomegalovirus infection     102961712 (ADCY1)   09174 Infectious disease: parasitic    05146 Amoebiasis     102961712 (ADCY1)    05142 Chagas disease     102961712 (ADCY1)   09165 Substance dependence    05032 Morphine addiction     102961712 (ADCY1)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102961712 (ADCY1)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102961712 (ADCY1)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102961712 (ADCY1) Enzymes [BR:ptg01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102961712 (ADCY1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom DUF6688 DUF6594 Motif Other DBs NCBI-GeneID:  102961712 NCBI-ProteinID:  XP_007073559 LinkDB All DBs Position Un AA seq 962 aa AA seqDB search MYGVFVRILAERSQRKAFLQARNCIEDRLRLEDENEKQERLLMSLLPRNVAMGVKGDFPK PQEVESVPILQEEQNKTELAECPPSNAKRLTVSGHPLAMVRHGPPWAGRRHGGRGTGPPV SLGGEQELVAWSSGPVWLILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCR RIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVL CGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNSF LKAHNIETFFIVPSHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFS NVLTCEDDDKRRALRTASEKLRNRSSFSANAVYTTPGTRVNRYIGRLLEARQTELEMADL DFFTLKYKQAERERKYHQLQDEYFTSAVVLALVLAALFGLVYLLIIPQNLVLLLLLAFCI CFLVACVLYLHVTRVQCFPGCLTIQIRTVLCIFVVVLIYSVAQGCVVSISTGSRARWSPG GVRCGRGPRGLLSCLVGTLPLAVFLRVSSLPKMILLFVLTTSYILVLELSGYTRAPGGGV ASGRSFEPIMAILLFSCTLALHARQVDVKLRLDYLWAAQAEEERDDMERVKLDNKRILFN LLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFDDFYIELDGNNMGVECLRLLNE IIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTTGTKAKKGISSHLSTLADFAIEMF DVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGRIQ VTEEVHRLLRRGTYRFVCRGKVSVKGKGEMLTYFLEGRTDGNGSQARERKVCGYGRAGLQ GRLGTGPPPVSSMAGLPVRAGMGALQGSGLPPCPHGQHTLAVLVTVLVILVSSTYNMSLH GF NT seq 2889 nt NT seq  +upstreamnt  +downstreamnt atgtatggggtgtttgtgcgcatcctggccgagcgctcccagcggaaagccttcctgcaa gcccggaactgcatcgaagatcggctgaggctggaggatgagaacgagaagcaggagcgg ctgctcatgagccttctgccccggaatgttgccatgggggtgaagggggacttcccgaag ccccaggaggtagagagtgttcccattttacaggaagagcagaacaagacagagttggcc gagtgcccaccctccaacgccaagagactcactgtttccgggcacccactggccatggtc cgtcacgggccaccctgggctgggcgcaggcatggtggccgtggaactgggccccctgtg tccctggggggtgagcaggagctggtggcctggagttcaggccccgtatggctcatcctc tttgcggacattgtgggcttcacgggcctggcgtcgcagtgcacggcacaggagctggtc aagctcctcaacgagctgttcggcaagtttgatgaactggccacggagaatcactgtcgc cgcatcaagatcctaggggactgttattactgtgtgtccggcctcacccagcccaagacc gaccacgcccactgctgcgtggagatgggcctggacatgatcgacaccatcacgtctgtg gccgaggccaccgaggtggacctgaacatgcgcgtggggctgcacacaggcagggtcctc tgcggggtcctgggcctgcgcaagtggcagtacgatgtgtggtccaacgacgtgaccctg gccaacgtcatggaggcggctggcctacctgggaaggtccacatcacgaagacgaccctg gcgtgcctgaacggggactacgaggtggagccaggtcacggacatgagaggaacagtttt ctgaaagctcacaacatcgagaccttcttcatcgtgccgtcacatcggcggaagatattt ccagggctgatcctctctgacataaaaccagccaagaggatgaagttcaagaccgtgtgc tacctgctcgtgcagctgatgcactgtcggaagatgttcaaagcagagatcccgttctct aatgtcctgacgtgtgaggacgacgacaagcggagggcgctgagaaccgcgtcggagaaa ctgcgaaaccgctcgtcgttctccgcaaacgctgtctacaccaccccgggcacgcgtgtc aacaggtacatcggccgcctcctggaagcgcgccagacggagctggagatggcggacctg gacttcttcactctcaagtacaagcaggctgagcgggagcgcaagtaccaccagctccag gacgagtattttaccagcgccgtcgttctggccctcgtcctggccgccttgtttggcctc gtctacctgctcatcatcccacagaacctggtcctcctgctgctgctggccttctgtatc tgcttcctggtggcctgcgtcctgtacctgcacgtcacccgggtccagtgttttccaggg tgcctgacgattcagatccgcaccgtcttgtgtatcttcgtcgtggtcttaatctactcc gtggcccaaggatgtgtggtgagcatctcaacaggcagcagggcccgctggtctcctgga ggcgtgaggtgtggacgggggccgagggggctgctgtcctgccttgtgggtaccctcccg ctggccgtcttcctgcgggtgtcctccctgcccaaaatgatcctgctctttgtgctcacg acgtcctacatcctggtcctggagctcagcggctacaccagggcccccgggggcggcgtg gcgtcggggcgcagtttcgagccgatcatggccatcctgctgttttcctgcaccctggcc ctgcacgcccgtcaggtggacgtcaagctgcggctggactacctctgggcggcacaggca gaggaggagagagacgacatggagagggtgaagttggacaacaagaggattctcttcaac ctcctgccggcccacgtggctcagcacttcctcatgtccaacccccgcaacatggacctg tactaccagtcctactcacaggtgggcgtcatgtttgcttccatccccaacttcgacgac ttctacatcgagctggacggcaacaacatgggggtggagtgtctgcgtctcctgaacgag atcatcgcagacttcgacgagctcatggacaaagacttttacaaggacttggagaagatc aagaccatcgggagcacctacatggccgctgtggggctggcgcccaccactgggaccaag gccaagaagggcatctcctcccacctgagcacactggccgacttcgccatcgagatgttc gacgtcctggatgaaatcaactaccagtcttacaacgactttgtgctccgtgtgggcatc aacgtgggccctgtggtggctggggtgattggggctcggaggccgcagtacgacatctgg gggaacacggtcaacgtggccagtcggatggacagcaccggcgtccagggcagaatccag gtgaccgaggaggttcaccggctgctgcgccgggggacctaccgcttcgtgtgccgcggg aaggtcagcgtcaagggcaagggtgagatgctgacgtacttcctggaaggcaggacggac ggaaacggctcccaagccagggagcggaaagtgtgtggctacgggcgagccggcctccag ggcagactgggcacgggcccgcccccggtgtcctccatggccggcctcccggtcagagct gggatgggggctctgcagggctcagggctccccccctgcccccatggccagcacaccctg gctgttctggtcaccgtgctggtcatcttggtctccagtacttacaacatgagcctgcat ggattttga

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