KEGG   Pan troglodytes (chimpanzee): 453993
Entry
453993            CDS       T01005                                 
Symbol
PRKCB
Name
(RefSeq) protein kinase C beta type isoform X2
  KO
K19662  classical protein kinase C beta type [EC:2.7.11.13]
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr01521  EGFR tyrosine kinase inhibitor resistance
ptr04010  MAPK signaling pathway
ptr04012  ErbB signaling pathway
ptr04014  Ras signaling pathway
ptr04015  Rap1 signaling pathway
ptr04020  Calcium signaling pathway
ptr04062  Chemokine signaling pathway
ptr04064  NF-kappa B signaling pathway
ptr04066  HIF-1 signaling pathway
ptr04070  Phosphatidylinositol signaling system
ptr04071  Sphingolipid signaling pathway
ptr04150  mTOR signaling pathway
ptr04270  Vascular smooth muscle contraction
ptr04310  Wnt signaling pathway
ptr04370  VEGF signaling pathway
ptr04510  Focal adhesion
ptr04540  Gap junction
ptr04613  Neutrophil extracellular trap formation
ptr04650  Natural killer cell mediated cytotoxicity
ptr04662  B cell receptor signaling pathway
ptr04666  Fc gamma R-mediated phagocytosis
ptr04670  Leukocyte transendothelial migration
ptr04713  Circadian entrainment
ptr04720  Long-term potentiation
ptr04723  Retrograde endocannabinoid signaling
ptr04724  Glutamatergic synapse
ptr04725  Cholinergic synapse
ptr04726  Serotonergic synapse
ptr04727  GABAergic synapse
ptr04728  Dopaminergic synapse
ptr04730  Long-term depression
ptr04750  Inflammatory mediator regulation of TRP channels
ptr04911  Insulin secretion
ptr04912  GnRH signaling pathway
ptr04916  Melanogenesis
ptr04918  Thyroid hormone synthesis
ptr04919  Thyroid hormone signaling pathway
ptr04921  Oxytocin signaling pathway
ptr04925  Aldosterone synthesis and secretion
ptr04928  Parathyroid hormone synthesis, secretion and action
ptr04929  GnRH secretion
ptr04931  Insulin resistance
ptr04933  AGE-RAGE signaling pathway in diabetic complications
ptr04935  Growth hormone synthesis, secretion and action
ptr04960  Aldosterone-regulated sodium reabsorption
ptr04961  Endocrine and other factor-regulated calcium reabsorption
ptr04970  Salivary secretion
ptr04971  Gastric acid secretion
ptr04972  Pancreatic secretion
ptr04973  Carbohydrate digestion and absorption
ptr05017  Spinocerebellar ataxia
ptr05022  Pathways of neurodegeneration - multiple diseases
ptr05031  Amphetamine addiction
ptr05032  Morphine addiction
ptr05140  Leishmaniasis
ptr05143  African trypanosomiasis
ptr05146  Amoebiasis
ptr05161  Hepatitis B
ptr05163  Human cytomegalovirus infection
ptr05164  Influenza A
ptr05170  Human immunodeficiency virus 1 infection
ptr05171  Coronavirus disease - COVID-19
ptr05200  Pathways in cancer
ptr05205  Proteoglycans in cancer
ptr05206  MicroRNAs in cancer
ptr05207  Chemical carcinogenesis - receptor activation
ptr05214  Glioma
ptr05223  Non-small cell lung cancer
ptr05225  Hepatocellular carcinoma
ptr05231  Choline metabolism in cancer
ptr05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    453993 (PRKCB)
   04012 ErbB signaling pathway
    453993 (PRKCB)
   04014 Ras signaling pathway
    453993 (PRKCB)
   04015 Rap1 signaling pathway
    453993 (PRKCB)
   04310 Wnt signaling pathway
    453993 (PRKCB)
   04370 VEGF signaling pathway
    453993 (PRKCB)
   04064 NF-kappa B signaling pathway
    453993 (PRKCB)
   04066 HIF-1 signaling pathway
    453993 (PRKCB)
   04020 Calcium signaling pathway
    453993 (PRKCB)
   04070 Phosphatidylinositol signaling system
    453993 (PRKCB)
   04071 Sphingolipid signaling pathway
    453993 (PRKCB)
   04150 mTOR signaling pathway
    453993 (PRKCB)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    453993 (PRKCB)
   04540 Gap junction
    453993 (PRKCB)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    453993 (PRKCB)
   04650 Natural killer cell mediated cytotoxicity
    453993 (PRKCB)
   04662 B cell receptor signaling pathway
    453993 (PRKCB)
   04666 Fc gamma R-mediated phagocytosis
    453993 (PRKCB)
   04670 Leukocyte transendothelial migration
    453993 (PRKCB)
   04062 Chemokine signaling pathway
    453993 (PRKCB)
  09152 Endocrine system
   04911 Insulin secretion
    453993 (PRKCB)
   04929 GnRH secretion
    453993 (PRKCB)
   04912 GnRH signaling pathway
    453993 (PRKCB)
   04921 Oxytocin signaling pathway
    453993 (PRKCB)
   04935 Growth hormone synthesis, secretion and action
    453993 (PRKCB)
   04918 Thyroid hormone synthesis
    453993 (PRKCB)
   04919 Thyroid hormone signaling pathway
    453993 (PRKCB)
   04928 Parathyroid hormone synthesis, secretion and action
    453993 (PRKCB)
   04916 Melanogenesis
    453993 (PRKCB)
   04925 Aldosterone synthesis and secretion
    453993 (PRKCB)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    453993 (PRKCB)
  09154 Digestive system
   04970 Salivary secretion
    453993 (PRKCB)
   04971 Gastric acid secretion
    453993 (PRKCB)
   04972 Pancreatic secretion
    453993 (PRKCB)
   04973 Carbohydrate digestion and absorption
    453993 (PRKCB)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    453993 (PRKCB)
   04961 Endocrine and other factor-regulated calcium reabsorption
    453993 (PRKCB)
  09156 Nervous system
   04724 Glutamatergic synapse
    453993 (PRKCB)
   04727 GABAergic synapse
    453993 (PRKCB)
   04725 Cholinergic synapse
    453993 (PRKCB)
   04728 Dopaminergic synapse
    453993 (PRKCB)
   04726 Serotonergic synapse
    453993 (PRKCB)
   04720 Long-term potentiation
    453993 (PRKCB)
   04730 Long-term depression
    453993 (PRKCB)
   04723 Retrograde endocannabinoid signaling
    453993 (PRKCB)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    453993 (PRKCB)
  09159 Environmental adaptation
   04713 Circadian entrainment
    453993 (PRKCB)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    453993 (PRKCB)
   05206 MicroRNAs in cancer
    453993 (PRKCB)
   05205 Proteoglycans in cancer
    453993 (PRKCB)
   05207 Chemical carcinogenesis - receptor activation
    453993 (PRKCB)
   05231 Choline metabolism in cancer
    453993 (PRKCB)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    453993 (PRKCB)
   05214 Glioma
    453993 (PRKCB)
   05223 Non-small cell lung cancer
    453993 (PRKCB)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    453993 (PRKCB)
   05161 Hepatitis B
    453993 (PRKCB)
   05171 Coronavirus disease - COVID-19
    453993 (PRKCB)
   05164 Influenza A
    453993 (PRKCB)
   05163 Human cytomegalovirus infection
    453993 (PRKCB)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    453993 (PRKCB)
   05140 Leishmaniasis
    453993 (PRKCB)
   05143 African trypanosomiasis
    453993 (PRKCB)
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    453993 (PRKCB)
   05022 Pathways of neurodegeneration - multiple diseases
    453993 (PRKCB)
  09165 Substance dependence
   05031 Amphetamine addiction
    453993 (PRKCB)
   05032 Morphine addiction
    453993 (PRKCB)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    453993 (PRKCB)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    453993 (PRKCB)
   04933 AGE-RAGE signaling pathway in diabetic complications
    453993 (PRKCB)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    453993 (PRKCB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ptr01001]
    453993 (PRKCB)
Enzymes [BR:ptr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     453993 (PRKCB)
Protein kinases [BR:ptr01001]
 Serine/threonine kinases: AGC group
  PKC family [OT]
   453993 (PRKCB)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr C1_1 C2 Pkinase_C Kinase-like Haspin_kinase ABC1 CEP76-C2
Other DBs
NCBI-GeneID: 453993
NCBI-ProteinID: XP_003315067
Ensembl: ENSPTRG00000007895
VGNC: 8996
UniProt: H2QAS7 A0A663DIT6
LinkDB
Position
16:25299998..25681027
AA seq 671 aa
MADPAAGPPPSEGEESTVRFARKGALRQKNVHEVKNHKFTARFFKQPTFCSHCTDFIWGF
GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGS
LLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIDRDVLIVLVRDA
KNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRL
SVEIWDWDLTSRNDFMGSLSFGISELQKASVDGWFKLLSQEEGEYFNVPVPPEGSEANEE
LRQKFERAKISQGTKVPEEKTTNTVSKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSE
RKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVM
EYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHI
KIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAP
FEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFF
RYIDWEKLERKEIQPPYKPKARDKRDTSNFDKEFTRQPVELTPTDKLFIMNLDQNEFAGF
SYTNPEFVINV
NT seq 2016 nt   +upstreamnt  +downstreamnt
atggctgacccggctgcggggccgccgccgagcgagggcgaggagagcaccgtgcgcttc
gcccgcaaaggcgccctccggcagaagaacgtgcatgaggtcaagaaccacaaattcacc
gcccgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctggggcttc
gggaagcagggattccagtgccaagtttgctgctttgtggtgcacaagcggtgccatgaa
tttgtcacattctcctgccctggcgctgacaagggtccagcctccgatgacccccggagc
aaacacaagtttaagatccacacgtactccagccccacgttttgtgaccactgtgggtca
ctgctgtatggactcatccaccaggggatgaaatgtgacacctgcatgatgaatgtgcac
aagcgctgcgtgatgaatgttcccagcctgtgtggcacggaccacacggagcgccgcggc
cgcatctacatccaggcccacatcgacagggacgtcctcattgtcctcgtaagagatgct
aaaaaccttgtacctatggaccccaatggcctgtcagatccctacgtaaaactgaaactg
attcccgatcccaaaagtgagagcaaacagaagaccaaaaccatcaaatgctccctcaac
cctgagtggaatgagacatttagatttcagctgaaagaatcggacaaagacagaagactg
tcagtagagatttgggattgggatttgaccagcaggaatgacttcatgggatctttgtcc
tttgggatttctgaacttcagaaagccagtgttgatggctggtttaagttactgagccag
gaggaaggcgagtacttcaatgtgcctgtgccaccggaaggaagtgaggccaatgaagaa
ctgcggcagaaatttgagagggccaagatcagtcagggaaccaaggtcccggaagaaaag
acgaccaacactgtctccaaatttgacaacaatggcaacagagaccggatgaaactgacc
gattttaacttcctaatggtgctggggaaaggcagctttggcaaggtcatgctttcagaa
cgaaaaggcacagatgagctctatgctgtgaagatcctgaagaaggacgttgtgatccaa
gatgatgacgtggagtgcactatggtggagaagcgggtgttggccctgcccgggaagccg
cccttcctgacccagctccactcctgcttccagaccatggaccgcctgtactttgtgatg
gagtacgtgaatgggggcgacctcatgtatcacatccagcaagtcggccggttcaaggag
ccccatgctgtattttacgctgcagaaattgccatcggtctgttcttcttacagagtaag
ggcatcatttaccgtgacctaaaacttgacaacgtgatgctcgattctgagggacacatc
aagattgccgattttggcatgtgtaaggaaaacatctgggatggggtgacaaccaagaca
ttctgtggcactccagactacatcgcccccgagataattgcttatcagccctatgggaag
tccgtggattggtgggcatttggagtcctgctgtatgaaatgttggctgggcaggcaccc
tttgaaggggaagatgaagatgaactcttccaatccatcatggaacacaacgtagcctat
cccaagtctatgtccaaggaagctgtggccatctgcaaagggctgatgaccaaacacccg
ggcaaacgtctgggttgtggacctgaaggcgaacgtgatatcaaagagcatgcatttttc
cggtatattgattgggagaaacttgaacgcaaagagatccagcccccatataagccaaaa
gctagagacaagagagacacctccaacttcgacaaagagttcaccagacagcctgtggaa
ctgacccccactgataaactcttcatcatgaacttggaccaaaatgaatttgctggcttc
tcttatactaacccagagtttgtcattaatgtgtag

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