KEGG   Pan troglodytes (chimpanzee): 462644
Entry
462644            CDS       T01005                                 
Symbol
MAPK13
Name
(RefSeq) mitogen-activated protein kinase 13
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr01522  Endocrine resistance
ptr04010  MAPK signaling pathway
ptr04015  Rap1 signaling pathway
ptr04068  FoxO signaling pathway
ptr04071  Sphingolipid signaling pathway
ptr04114  Oocyte meiosis
ptr04148  Efferocytosis
ptr04218  Cellular senescence
ptr04261  Adrenergic signaling in cardiomyocytes
ptr04370  VEGF signaling pathway
ptr04380  Osteoclast differentiation
ptr04550  Signaling pathways regulating pluripotency of stem cells
ptr04611  Platelet activation
ptr04613  Neutrophil extracellular trap formation
ptr04620  Toll-like receptor signaling pathway
ptr04621  NOD-like receptor signaling pathway
ptr04622  RIG-I-like receptor signaling pathway
ptr04625  C-type lectin receptor signaling pathway
ptr04657  IL-17 signaling pathway
ptr04658  Th1 and Th2 cell differentiation
ptr04659  Th17 cell differentiation
ptr04660  T cell receptor signaling pathway
ptr04664  Fc epsilon RI signaling pathway
ptr04668  TNF signaling pathway
ptr04670  Leukocyte transendothelial migration
ptr04714  Thermogenesis
ptr04722  Neurotrophin signaling pathway
ptr04723  Retrograde endocannabinoid signaling
ptr04728  Dopaminergic synapse
ptr04750  Inflammatory mediator regulation of TRP channels
ptr04912  GnRH signaling pathway
ptr04914  Progesterone-mediated oocyte maturation
ptr04917  Prolactin signaling pathway
ptr04926  Relaxin signaling pathway
ptr04932  Non-alcoholic fatty liver disease
ptr04933  AGE-RAGE signaling pathway in diabetic complications
ptr04935  Growth hormone synthesis, secretion and action
ptr04936  Alcoholic liver disease
ptr05014  Amyotrophic lateral sclerosis
ptr05020  Prion disease
ptr05022  Pathways of neurodegeneration - multiple diseases
ptr05132  Salmonella infection
ptr05133  Pertussis
ptr05135  Yersinia infection
ptr05140  Leishmaniasis
ptr05142  Chagas disease
ptr05145  Toxoplasmosis
ptr05152  Tuberculosis
ptr05161  Hepatitis B
ptr05163  Human cytomegalovirus infection
ptr05167  Kaposi sarcoma-associated herpesvirus infection
ptr05169  Epstein-Barr virus infection
ptr05170  Human immunodeficiency virus 1 infection
ptr05171  Coronavirus disease - COVID-19
ptr05205  Proteoglycans in cancer
ptr05208  Chemical carcinogenesis - reactive oxygen species
ptr05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ptr05415  Diabetic cardiomyopathy
ptr05417  Lipid and atherosclerosis
ptr05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    462644 (MAPK13)
   04015 Rap1 signaling pathway
    462644 (MAPK13)
   04370 VEGF signaling pathway
    462644 (MAPK13)
   04668 TNF signaling pathway
    462644 (MAPK13)
   04068 FoxO signaling pathway
    462644 (MAPK13)
   04071 Sphingolipid signaling pathway
    462644 (MAPK13)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    462644 (MAPK13)
  09143 Cell growth and death
   04114 Oocyte meiosis
    462644 (MAPK13)
   04218 Cellular senescence
    462644 (MAPK13)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    462644 (MAPK13)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    462644 (MAPK13)
   04613 Neutrophil extracellular trap formation
    462644 (MAPK13)
   04620 Toll-like receptor signaling pathway
    462644 (MAPK13)
   04621 NOD-like receptor signaling pathway
    462644 (MAPK13)
   04622 RIG-I-like receptor signaling pathway
    462644 (MAPK13)
   04625 C-type lectin receptor signaling pathway
    462644 (MAPK13)
   04660 T cell receptor signaling pathway
    462644 (MAPK13)
   04658 Th1 and Th2 cell differentiation
    462644 (MAPK13)
   04659 Th17 cell differentiation
    462644 (MAPK13)
   04657 IL-17 signaling pathway
    462644 (MAPK13)
   04664 Fc epsilon RI signaling pathway
    462644 (MAPK13)
   04670 Leukocyte transendothelial migration
    462644 (MAPK13)
  09152 Endocrine system
   04912 GnRH signaling pathway
    462644 (MAPK13)
   04914 Progesterone-mediated oocyte maturation
    462644 (MAPK13)
   04917 Prolactin signaling pathway
    462644 (MAPK13)
   04926 Relaxin signaling pathway
    462644 (MAPK13)
   04935 Growth hormone synthesis, secretion and action
    462644 (MAPK13)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    462644 (MAPK13)
  09156 Nervous system
   04728 Dopaminergic synapse
    462644 (MAPK13)
   04723 Retrograde endocannabinoid signaling
    462644 (MAPK13)
   04722 Neurotrophin signaling pathway
    462644 (MAPK13)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    462644 (MAPK13)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    462644 (MAPK13)
  09159 Environmental adaptation
   04714 Thermogenesis
    462644 (MAPK13)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    462644 (MAPK13)
   05208 Chemical carcinogenesis - reactive oxygen species
    462644 (MAPK13)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    462644 (MAPK13)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    462644 (MAPK13)
   05161 Hepatitis B
    462644 (MAPK13)
   05171 Coronavirus disease - COVID-19
    462644 (MAPK13)
   05163 Human cytomegalovirus infection
    462644 (MAPK13)
   05167 Kaposi sarcoma-associated herpesvirus infection
    462644 (MAPK13)
   05169 Epstein-Barr virus infection
    462644 (MAPK13)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    462644 (MAPK13)
   05135 Yersinia infection
    462644 (MAPK13)
   05133 Pertussis
    462644 (MAPK13)
   05152 Tuberculosis
    462644 (MAPK13)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    462644 (MAPK13)
   05140 Leishmaniasis
    462644 (MAPK13)
   05142 Chagas disease
    462644 (MAPK13)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    462644 (MAPK13)
   05020 Prion disease
    462644 (MAPK13)
   05022 Pathways of neurodegeneration - multiple diseases
    462644 (MAPK13)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    462644 (MAPK13)
   05418 Fluid shear stress and atherosclerosis
    462644 (MAPK13)
   05415 Diabetic cardiomyopathy
    462644 (MAPK13)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    462644 (MAPK13)
   04932 Non-alcoholic fatty liver disease
    462644 (MAPK13)
   04933 AGE-RAGE signaling pathway in diabetic complications
    462644 (MAPK13)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    462644 (MAPK13)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ptr01001]
    462644 (MAPK13)
Enzymes [BR:ptr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     462644 (MAPK13)
Protein kinases [BR:ptr01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   462644 (MAPK13)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Kinase-like Kdo DUF4023 US2
Other DBs
NCBI-GeneID: 462644
NCBI-ProteinID: NP_001029261
Ensembl: ENSPTRG00000018098
VGNC: 7195
UniProt: Q9N272 K7AUK7 A0A6D2W9Q9
LinkDB
Position
6:35628995..35640445
AA seq 365 aa
MSLIRKKGFYKQDVNKTAWELPKTYVSPTHVGSGAYGSVCSAIDKRSGEKVAIKKLSRPF
QSEIFAKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFHDFYLVMPFMQTDLQKIMGM
EFSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEMT
GYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTG
VPGTEFVQKLNDKAAKSYIQSLPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTAA
QALTHPFFEPFRDPEEETEAQQPFDDSLEHEKLTVDEWKQHIYKEIVNFSPIARKDSRRR
SGMKL
NT seq 1098 nt   +upstreamnt  +downstreamnt
atgagcctcatccggaaaaagggcttctacaagcaggacgtcaacaagaccgcctgggag
ctgcccaagacctacgtgtccccgacgcacgtcggcagcggggcctatggctccgtgtgc
tcggccatcgacaagcggtcaggggagaaggtggccatcaagaagctgagccgacccttt
cagtccgagatcttcgccaagcgcgcctaccgggagctgctgctgctgaagcacatgcag
catgagaacgtcattgggctcctggatgtcttcaccccagcctcctccctgcgcaacttc
catgacttctacctggtgatgcccttcatgcagacggatctgcagaagatcatggggatg
gagttcagtgaggagaagatccagtacctggtgtatcagatgctcaaaggccttaagtac
atccactcggctggggtcgtgcacagggacctgaagccaggcaacctggctgtgaatgag
gactgtgaactgaagattctggattttgggctggcgcgacatgcagacgccgagatgact
ggctacgtggtgacccgctggtaccgagcccccgaggtgatcctcagctggatgcactac
aaccagacagtggacatctggtctgtgggctgtatcatggcagagatgctgacagggaaa
actctgttcaaggggaaagattacctggaccagctgacccagatcctgaaagtgaccggg
gtgcctggcacggagtttgtgcagaagctgaacgacaaagcggccaaatcctacatccag
tccctgccacagacccccaggaaggatttcactcagctgttcccacgggccagcccccag
gctgcggacctgctggagaagatgctggagctagacgtggacaagcgcctgacggctgcg
caggccctcacccatcccttctttgaacccttccgggaccctgaggaagagacggaggcc
cagcagccgtttgatgattccttagaacacgagaaactcacagtggatgaatggaagcag
cacatctacaaggagattgtgaacttcagccccattgcccggaaggactcacggcgccgg
agtggcatgaagctgtag

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