Prionailurus viverrinus (fishing cat): 125157150
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Entry
125157150 CDS
T09889
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
pviv
Prionailurus viverrinus (fishing cat)
Pathway
pviv00010
Glycolysis / Gluconeogenesis
pviv00020
Citrate cycle (TCA cycle)
pviv00620
Pyruvate metabolism
pviv00785
Lipoic acid metabolism
pviv01100
Metabolic pathways
pviv01200
Carbon metabolism
pviv01210
2-Oxocarboxylic acid metabolism
pviv04066
HIF-1 signaling pathway
pviv04922
Glucagon signaling pathway
pviv05230
Central carbon metabolism in cancer
pviv05415
Diabetic cardiomyopathy
Module
pviv_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
pviv00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
125157150 (PDHA1)
00020 Citrate cycle (TCA cycle)
125157150 (PDHA1)
00620 Pyruvate metabolism
125157150 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
125157150 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
125157150 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
125157150 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
125157150 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
125157150 (PDHA1)
Enzymes [BR:
pviv01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
125157150 (PDHA1)
BRITE hierarchy
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
125157150
NCBI-ProteinID:
XP_047699405
LinkDB
All DBs
Position
X:12289095..12305977
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AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGVAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSDPPFEVRGANQWIKFKSIS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaaaatgctcgcagctgtctcccgcgtgttgtcgggcgtcgcccagaagccggca
agcagagtgctggtggcatcccgtaattttgcaaatgatgctacatttgaaattaagaaa
tgtgatcttcaccgactggaagagggccctcctgtcaccacggtactcaccagggaggat
gggctcaaatactataggatgatgcagactgttcgccgaatggaattaaaggcagatcag
ctgtataaacagaaaattattcgtggtttttgtcacttgtgtgatggtcaggaagcttgt
tgtgtgggcctggaggccggcataaatcccacagaccatcttatcacagcctatcgggct
catggcttcacctttactcgtggactttctgtccgagaaattcttgcagagcttacagga
cgaagaggaggttgcgctaaagggaaaggcggatcgatgcatatgtatgccaaaaacttc
tacgggggcaacggcatcgtcggagctcaggtgcccctgggagcagggattgctctggcc
tgtaagtataacggaaaggatgaggtctgtttgactttatatggcgatggtgctgctaac
caaggtcagatattcgaagcttacaatatggcagctttgtggaaattgccatgtattttc
atctgtgaaaataaccgctatggaatgggaacatctgttgagagagcagcggccagcacg
gattactacaagagaggtgacttcattcctgggctgagggtagatggaatggatatcctg
tgtgtccgcgaggcgacgaggtttgcagccgcctactgtagatctggaaaggggcccata
ctgatggagctacagacttaccgctaccacggacatagcatgagtgatcctggtgtcagt
taccgtacacgagaggagattcaggaagtaagaagtaagagtgaccctattatgcttctc
aaggatagaatggtgaacagcaacctggccagtgttgaagaattaaaggaaattgatgtt
gaagtgaggaaagagattgaggatgctgcccagtttgccaccgctgatcctgaaccgcct
ctggaagaactaggctatcacatttacagcagcgacccaccttttgaagttcggggtgca
aatcagtggatcaagtttaagtccatcagttaa
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