Pteropus vampyrus (large flying fox): 105300978
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Entry
105300978 CDS
T07815
Symbol
HSD17B8
Name
(RefSeq) estradiol 17-beta-dehydrogenase 8
KO
K13370
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) / 3-oxoacyl-[acyl-carrier protein] reductase alpha subunit [EC:
1.1.1.62
1.1.1.239
]
Organism
pvp
Pteropus vampyrus (large flying fox)
Pathway
pvp00061
Fatty acid biosynthesis
pvp00140
Steroid hormone biosynthesis
pvp01100
Metabolic pathways
pvp01212
Fatty acid metabolism
Module
pvp_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
pvp00001
]
09100 Metabolism
09103 Lipid metabolism
00061 Fatty acid biosynthesis
105300978 (HSD17B8)
00140 Steroid hormone biosynthesis
105300978 (HSD17B8)
Enzymes [BR:
pvp01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
105300978 (HSD17B8)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
105300978 (HSD17B8)
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GFIT
Motif
Pfam:
adh_short_C2
adh_short
KR
Epimerase
THF_DHG_CYH_C
RmlD_sub_bind
RNA_pol_Rpb1_4
Motif
Other DBs
NCBI-GeneID:
105300978
NCBI-ProteinID:
XP_011371742
UniProt:
A0A6P3QWX0
LinkDB
All DBs
Position
Unknown
AA seq
259 aa
AA seq
DB search
MATQLRFRSALALVTGAGSGIGRAVSVRLAREGATVAVCDLDGAAVHETVRLLGRPGSEK
GASCGAHAAFQADVSEAGAARRLLEQVQACFSRPPSVIVSCAGVTRDEFLLHMSEDDWDR
VISVNLKGVFLVTQAAAQALVSSGCHGSIVNISSIVGKVGNMGQANYAASKAGVIGLTQT
VALELGRHGIRCNSVLPGYITTPMTQKVPQKILDKVFRAIPMGRFGDPEDVADVVAFLAS
DDSGYITGASVEVTGGLFL
NT seq
780 nt
NT seq
+upstream
nt +downstream
nt
atggcgacccagctccggttccgctccgcactggcccttgtcacaggtgcgggtagcggc
atcggccgagcagtcagtgtgcgcttggcccgagagggggccaccgtggccgtttgcgac
ctggatggggcagcggtacacgagacagtgcggctgttgggcaggccaggaagcgagaag
ggggcgtcctgtggggcccacgctgccttccaggctgacgtgtctgaggccggggctgcc
aggcgcttgctggaacaagtgcaggcctgcttttctcgcccgccttctgtcattgtgtcc
tgtgcgggagttaccagggatgagtttctgctccatatgtccgaggatgactgggacaga
gtcatatctgtcaacctcaagggcgtctttctagtcactcaagctgcagcccaagccctg
gtgtccagtggttgtcatggctccatcgtcaacatcagtagcatcgtaggcaaggtgggg
aacatgggacaggcaaactatgcagcatccaaggctggagtgattgggctgacccagact
gtagccctggagcttggacgacatgggatccgctgtaactctgtcctcccagggtacatt
acaacacctatgacacagaaagtgccacagaaaattctggacaaggtgtttagagcgatt
ccgatgggacgtttcggggaccctgaggatgtggcagatgtggttgcattcttggcatct
gatgacagtggatacatcacaggggcctcagtagaagtcactggaggtcttttcttgtaa
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