KEGG   Pteropus vampyrus (large flying fox): 105301035
Entry
105301035         CDS       T07815                                 
Symbol
MAPK14
Name
(RefSeq) mitogen-activated protein kinase 14 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
pvp  Pteropus vampyrus (large flying fox)
Pathway
pvp01522  Endocrine resistance
pvp04010  MAPK signaling pathway
pvp04015  Rap1 signaling pathway
pvp04068  FoxO signaling pathway
pvp04071  Sphingolipid signaling pathway
pvp04114  Oocyte meiosis
pvp04148  Efferocytosis
pvp04218  Cellular senescence
pvp04261  Adrenergic signaling in cardiomyocytes
pvp04370  VEGF signaling pathway
pvp04380  Osteoclast differentiation
pvp04550  Signaling pathways regulating pluripotency of stem cells
pvp04611  Platelet activation
pvp04613  Neutrophil extracellular trap formation
pvp04620  Toll-like receptor signaling pathway
pvp04621  NOD-like receptor signaling pathway
pvp04622  RIG-I-like receptor signaling pathway
pvp04625  C-type lectin receptor signaling pathway
pvp04657  IL-17 signaling pathway
pvp04658  Th1 and Th2 cell differentiation
pvp04659  Th17 cell differentiation
pvp04660  T cell receptor signaling pathway
pvp04664  Fc epsilon RI signaling pathway
pvp04668  TNF signaling pathway
pvp04670  Leukocyte transendothelial migration
pvp04714  Thermogenesis
pvp04722  Neurotrophin signaling pathway
pvp04723  Retrograde endocannabinoid signaling
pvp04728  Dopaminergic synapse
pvp04750  Inflammatory mediator regulation of TRP channels
pvp04912  GnRH signaling pathway
pvp04914  Progesterone-mediated oocyte maturation
pvp04917  Prolactin signaling pathway
pvp04926  Relaxin signaling pathway
pvp04932  Non-alcoholic fatty liver disease
pvp04933  AGE-RAGE signaling pathway in diabetic complications
pvp04935  Growth hormone synthesis, secretion and action
pvp04936  Alcoholic liver disease
pvp05014  Amyotrophic lateral sclerosis
pvp05020  Prion disease
pvp05022  Pathways of neurodegeneration - multiple diseases
pvp05132  Salmonella infection
pvp05133  Pertussis
pvp05135  Yersinia infection
pvp05140  Leishmaniasis
pvp05142  Chagas disease
pvp05145  Toxoplasmosis
pvp05152  Tuberculosis
pvp05161  Hepatitis B
pvp05163  Human cytomegalovirus infection
pvp05167  Kaposi sarcoma-associated herpesvirus infection
pvp05169  Epstein-Barr virus infection
pvp05170  Human immunodeficiency virus 1 infection
pvp05171  Coronavirus disease - COVID-19
pvp05205  Proteoglycans in cancer
pvp05208  Chemical carcinogenesis - reactive oxygen species
pvp05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pvp05415  Diabetic cardiomyopathy
pvp05417  Lipid and atherosclerosis
pvp05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pvp00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105301035 (MAPK14)
   04015 Rap1 signaling pathway
    105301035 (MAPK14)
   04370 VEGF signaling pathway
    105301035 (MAPK14)
   04668 TNF signaling pathway
    105301035 (MAPK14)
   04068 FoxO signaling pathway
    105301035 (MAPK14)
   04071 Sphingolipid signaling pathway
    105301035 (MAPK14)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    105301035 (MAPK14)
  09143 Cell growth and death
   04114 Oocyte meiosis
    105301035 (MAPK14)
   04218 Cellular senescence
    105301035 (MAPK14)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    105301035 (MAPK14)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    105301035 (MAPK14)
   04613 Neutrophil extracellular trap formation
    105301035 (MAPK14)
   04620 Toll-like receptor signaling pathway
    105301035 (MAPK14)
   04621 NOD-like receptor signaling pathway
    105301035 (MAPK14)
   04622 RIG-I-like receptor signaling pathway
    105301035 (MAPK14)
   04625 C-type lectin receptor signaling pathway
    105301035 (MAPK14)
   04660 T cell receptor signaling pathway
    105301035 (MAPK14)
   04658 Th1 and Th2 cell differentiation
    105301035 (MAPK14)
   04659 Th17 cell differentiation
    105301035 (MAPK14)
   04657 IL-17 signaling pathway
    105301035 (MAPK14)
   04664 Fc epsilon RI signaling pathway
    105301035 (MAPK14)
   04670 Leukocyte transendothelial migration
    105301035 (MAPK14)
  09152 Endocrine system
   04912 GnRH signaling pathway
    105301035 (MAPK14)
   04914 Progesterone-mediated oocyte maturation
    105301035 (MAPK14)
   04917 Prolactin signaling pathway
    105301035 (MAPK14)
   04926 Relaxin signaling pathway
    105301035 (MAPK14)
   04935 Growth hormone synthesis, secretion and action
    105301035 (MAPK14)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    105301035 (MAPK14)
  09156 Nervous system
   04728 Dopaminergic synapse
    105301035 (MAPK14)
   04723 Retrograde endocannabinoid signaling
    105301035 (MAPK14)
   04722 Neurotrophin signaling pathway
    105301035 (MAPK14)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    105301035 (MAPK14)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    105301035 (MAPK14)
  09159 Environmental adaptation
   04714 Thermogenesis
    105301035 (MAPK14)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    105301035 (MAPK14)
   05208 Chemical carcinogenesis - reactive oxygen species
    105301035 (MAPK14)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    105301035 (MAPK14)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    105301035 (MAPK14)
   05161 Hepatitis B
    105301035 (MAPK14)
   05171 Coronavirus disease - COVID-19
    105301035 (MAPK14)
   05163 Human cytomegalovirus infection
    105301035 (MAPK14)
   05167 Kaposi sarcoma-associated herpesvirus infection
    105301035 (MAPK14)
   05169 Epstein-Barr virus infection
    105301035 (MAPK14)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    105301035 (MAPK14)
   05135 Yersinia infection
    105301035 (MAPK14)
   05133 Pertussis
    105301035 (MAPK14)
   05152 Tuberculosis
    105301035 (MAPK14)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    105301035 (MAPK14)
   05140 Leishmaniasis
    105301035 (MAPK14)
   05142 Chagas disease
    105301035 (MAPK14)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    105301035 (MAPK14)
   05020 Prion disease
    105301035 (MAPK14)
   05022 Pathways of neurodegeneration - multiple diseases
    105301035 (MAPK14)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105301035 (MAPK14)
   05418 Fluid shear stress and atherosclerosis
    105301035 (MAPK14)
   05415 Diabetic cardiomyopathy
    105301035 (MAPK14)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    105301035 (MAPK14)
   04932 Non-alcoholic fatty liver disease
    105301035 (MAPK14)
   04933 AGE-RAGE signaling pathway in diabetic complications
    105301035 (MAPK14)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    105301035 (MAPK14)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pvp01001]
    105301035 (MAPK14)
Enzymes [BR:pvp01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     105301035 (MAPK14)
Protein kinases [BR:pvp01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   105301035 (MAPK14)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH NAD_binding_8
Other DBs
NCBI-GeneID: 105301035
NCBI-ProteinID: XP_011371844
UniProt: A0A6P3RCN5
LinkDB
Position
Unknown
AA seq 360 aa
MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG
TPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA
QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
NT seq 1083 nt   +upstreamnt  +downstreamnt
atgtctcaggaaaggcccacgttctaccggcaggagctgaacaagacaatctgggaggtg
ccagagcgttaccagaacctgtctccggtgggctccggcgcctatggctccgtgtgtgct
gcttttgacacaaaaactgggttacgtgtggcagtgaagaagctatccagaccatttcag
tccattattcatgccaaaaggacctacagagaactgcggttacttaaacatatgaaacat
gaaaatgtgattggtctgttggatgtttttacacctgcaaggtctctggaggaattcaat
gatgtgtatctagtgacccatctcatgggggcagatctgaacaacattgtgaaatgtcag
aagcttacagatgaccatgttcagttccttatctaccaaattctccgaggtctcaagtat
atacattcagccgacataattcacagggacctaaaacctagtaatctagctgtgaatgaa
gactgtgagctgaagatcctggattttggactggctcgacatacagatgatgaaatgaca
ggctatgtggccactaggtggtacagggctcctgagatcatgctgaactggatgcattac
aaccagacagttgatatttggtcagtgggatgcataatggccgagctgttgactggaaga
acgttgtttcctggtacagaccatattgatcagttgaagctcattttaagactcgttgga
accccaggggctgagcttttgaagaaaatctcctcagagtctgcaagaaactatattcag
tctttgacccagatgccgaagatgaactttgcaaatgtatttattggtgccaatcccttg
gctgttgacttgctggagaagatgcttgtattggactcagataagagaatcactgcagcc
caggccctcgcacatgcctactttgctcaatatcatgatcctgatgacgaaccagtggct
gatccttacgatcaatcctttgaaagcagggacctccttatagatgaatggaaaagcctg
acctacgatgaagtcatcagctttgtgccaccaccccttgaccaagaagagatggaatcc
tga

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