Pteropus vampyrus (large flying fox): 105309193
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Entry
105309193 CDS
T07815
Symbol
RET
Name
(RefSeq) proto-oncogene tyrosine-protein kinase receptor Ret isoform X4
KO
K05126
proto-oncogene tyrosine-protein kinase Ret [EC:
2.7.10.1
]
Organism
pvp
Pteropus vampyrus (large flying fox)
Pathway
pvp04010
MAPK signaling pathway
pvp04020
Calcium signaling pathway
pvp04151
PI3K-Akt signaling pathway
pvp05200
Pathways in cancer
pvp05216
Thyroid cancer
pvp05223
Non-small cell lung cancer
pvp05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
pvp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
105309193 (RET)
04020 Calcium signaling pathway
105309193 (RET)
04151 PI3K-Akt signaling pathway
105309193 (RET)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
105309193 (RET)
05230 Central carbon metabolism in cancer
105309193 (RET)
09162 Cancer: specific types
05216 Thyroid cancer
105309193 (RET)
05223 Non-small cell lung cancer
105309193 (RET)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pvp01001
]
105309193 (RET)
Enzymes [BR:
pvp01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
105309193 (RET)
Protein kinases [BR:
pvp01001
]
Receptor tyrosine kinases (RTK)
RET family
105309193 (RET)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
RET_CLD4
RET_CLD1
RET_CLD3
Pkinase
Cadherin
RIO1
Pkinase_fungal
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
105309193
NCBI-ProteinID:
XP_011383623
UniProt:
A0A6P3S1J8
LinkDB
All DBs
Position
Unknown
AA seq
1113 aa
AA seq
DB search
MAKATASTAGLRWLLLLPLFGEAPLGLYFSRDAYWEKLYVDQPAGMPLLYVHALRDVPEE
VPSFRLGQYLYSAYRTRLNENDWIRIQEDTGLLYLNWSLDHSSWEKLSVRNGGFPLLTVY
LQVFLSPTYLREGECQWPGCARVYFSFINTSFPVCDSLKPRELCFPETGLSFRIRENRPT
GTFHQFRLLPVQFLCPNISVAYRLLGGESLPFHCAADSLEVSTRWALDREHREKYELVAA
CTVRVGAREEQVMVPFPVTVYDEDDSAPTFLGGVDTASAVVEFKRKEGTVVATLHVFDAD
VVPASGELLRRYTSTLLPRDAWTFQTFRVEHSPNETLVQANGSFVRATVHDYRLVLNRSL
PISESRALQLAVLVNDSDFQGPGEGILLLHFNVSVLPVSLHLPSAYSFTVSRRAHRFAQV
GKLCVENCQEFTGIHVQYKLQLSSTNCSALGVVTSAEDNMGTLFVNDTEALQRPECTQLQ
YTVLASDRPTHRQAQAPLLVTIEGTYMAEEPGCPLSCAVSKRRPECEECGGLGSLTGRCE
WRQGDGKGISRNFSTCSPSIKTCPDGHCDSVESRNSNICPQDCLRGGSIIGGHEPGERWG
IKAGFGTCNCFPEEKKCFCEPEDSQDPLCDELCRTVIAAAVLFSFIISVLLSTFCIHRYH
KNAHKPPIASAEMTFRRPAQAFPVSYSSSSARRPSLDSMENQVSVDAFKIPEDPKWEFPR
KNLVLGKTLGEGEFGKVVEATAFRLKGKTGYMTVAVKMLKENASPNELRDLLSEFNLLKQ
VNHPNVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKAGPGYVGSRGSRNSSYLDNP
DERALTMGDLISFAWQISRGMRYLAEMKLVHRDLAARNVLVAEGRKMKISDFGLSRDVYE
EDSYVKRSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLF
NLLKTGYRMEKPDNCSEEMYSLMLQCWKEEPDKRPVFADISKDLEKMMVKRRDYLDLAAS
TPSDSLLYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGMSDPNWPEESPVPLTRAD
GTNTGCPRYANDSVYANWMVSPSAAQLMDSFDS
NT seq
3342 nt
NT seq
+upstream
nt +downstream
nt
atggcgaaggcgacggccagcaccgcggggctgcgatggctcctgctgctgccgctgttc
ggcgaagccccactgggactctacttctccagggatgcttactgggagaagctatatgtg
gaccagccggcgggcatgcctctgctctatgtccacgccctgcgtgacgtccccgaggag
gtgcccagcttccgcctgggccagtacctctacagcgcctaccgcacacggctgaatgag
aatgactggatccgtatccaggaggacacaggccttctgtacctgaactggagcctggac
cacagctcctgggagaagctcagcgtccgcaatggcggcttccccctgctcaccgtctat
ctccaggtctttctgtcgcccacatacctgcgtgagggcgagtgccagtggccaggctgt
gcccgcgtatacttctccttcatcaatacctccttccctgtgtgtgactccctgaaacct
cgggagctctgcttccctgagacaggcctctccttccgcattcgtgaaaacaggccaact
ggcaccttccaccagttccgcttgttgcctgtgcagttcctttgccccaacatcagcgtg
gcctacagactactgggaggtgagagtctacccttccactgtgctgcggacagcctggag
gtgagcacgcgttgggccttggaccgcgaacaccgggagaagtacgaactggtggcagcg
tgcaccgtgcgcgtgggcgcgcgcgaggagcaggtgatggtacccttccccgtgaccgtg
tacgacgaggacgactcggctcccaccttcctcggtggcgtcgacaccgccagcgctgtg
gtggaattcaagaggaaggagggaactgtggtggccacactacatgtcttcgatgcagat
gtggtgccagcatccggggagctcctgcgccggtacacaagcacactgctccccagggat
gcctggaccttccagaccttccgtgtggagcactcacccaacgaaaccttggtccaggcc
aacggcagctttgtgcgggcaaccgtgcatgactataggctggttctcaaccgcagcctc
cccatctcagagagccgtgccctgcagctggctgtgctggtcaatgactcggacttccag
ggcccaggggagggcatcctcctcctccacttcaatgtgtctgtgttgcccgtcagcttg
cacttgcccagcgcctattccttcactgtgagcaggagggcccaccgctttgcccaggtt
gggaaactctgtgtggaaaactgccaggagttcaccggcatccatgtgcaatacaaactg
cagctctccagtaccaactgtagtgccctgggagtggttacctcagccgaggacaacatg
gggaccctgtttgtgaatgacacagaggccctgcaacggcctgagtgtacccagctccag
tacacagtgctggcctctgaccggccaacccacaggcaggcccaggctccactgctcgtc
actatagagggtacatacatggctgaggagccgggctgccccctgtcctgtgcagtcagc
aagaggcggcctgagtgtgaggagtgcggcggcctgggctctctgacaggcaggtgcgag
tggagacagggagacggcaaagggatctccaggaacttctccacctgctcccccagcatc
aagacctgccctgatggccactgtgactccgtggagagcagaaattccaacatctgcccc
caggactgcctccggggcggcagcatcattggtgggcatgagccaggggagcgttgggga
attaaagccggctttggtacctgcaactgcttccctgaggagaagaagtgcttctgtgag
ccagaagacagccaggacccactatgtgatgagctctgccgcactgtgatcgcagcagct
gttctcttctccttcatcatctctgtgctgttgtccaccttctgcatccaccgctaccat
aagaacgcccacaagccgcccatcgcctcagccgagatgaccttccgccggccagcccag
gccttcccagtgagctactcctcgtctagtgcccgccggccctcactagattccatggag
aaccaggtctctgtggatgccttcaagatcccggaggatccaaagtgggaattccctcga
aagaacttggttcttggaaaaactctgggagaaggtgaatttggaaaagtcgtcgaagca
acagccttcaggctaaaaggcaaaacagggtacatgaccgtggccgtgaagatgctgaaa
gagaacgcctccccaaatgagctgcgggacctactgtcagaattcaacctcctgaagcag
gtcaaccaccccaatgtcatcaagctgtatggggcctgcagccaggatgggccactcctc
ctcattgtggagtatgctaagtacggctccttgcgcggcttcttgcgagaaagtcgcaag
gcaggacccggctatgtgggcagcagaggcagccgcaactccagctaccttgacaacccg
gatgagcgggccctgaccatgggcgacctcatctcctttgcctggcagatttcacgtggg
atgcggtacctggccgagatgaagcttgtccatcgggacttagcagccagaaatgtcctg
gtagctgaggggcggaagatgaagatttcagactttggcctgtcccgagatgtgtatgaa
gaggattcctacgtgaaaaggagcaagggtcggattccagtcaaatggatggcaattgag
tcccttttcgatcatatctacaccacccaaagtgatgtgtggtcctttggtgtcctcctg
tgggagattgtgaccttggggggcaacccctacccagggattcctcccgagcggctcttc
aaccttctgaagacaggctatcggatggagaagcctgacaactgcagtgaggagatgtac
agtctgatgctgcagtgctggaaggaggagccagacaagaggccagtgtttgctgacatc
agcaaagacctggagaagatgatggttaagagaagagactacttggacctggccgcatcc
accccatctgactccctgctttatgatgatggcctctcagaggaggagacgcccctggtg
gactgtaataatgctcccctccctcgagccctcccctccacgtggattgaaaacaaactc
tatggcatgtcagacccgaactggcctgaagagagtcctgtaccactcacgagagccgat
ggcactaacactgggtgtccaagatatgcaaatgatagtgtatatgctaactggatggtt
tcaccctcagcggcacaattaatggactcgtttgatagttaa
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