Plasmodium vivax: PVX_091840
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Entry
PVX_091840 CDS
T01073
Name
(RefSeq) pyruvate dehydrogenase E1 component, alpha subunit, putative
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
pvx
Plasmodium vivax
Pathway
pvx00010
Glycolysis / Gluconeogenesis
pvx00020
Citrate cycle (TCA cycle)
pvx00620
Pyruvate metabolism
pvx00785
Lipoic acid metabolism
pvx01100
Metabolic pathways
pvx01110
Biosynthesis of secondary metabolites
pvx01200
Carbon metabolism
pvx01210
2-Oxocarboxylic acid metabolism
Module
pvx_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
pvx00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
PVX_091840
00020 Citrate cycle (TCA cycle)
PVX_091840
00620 Pyruvate metabolism
PVX_091840
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
PVX_091840
Enzymes [BR:
pvx01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
PVX_091840
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
Transketolase_N
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
5474656
NCBI-ProteinID:
XP_001615360
UniProt:
A5K4Q5
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Position
9:889522..891015
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AA seq
497 aa
AA seq
DB search
MVKTHVVGSKRLDDPMVKIFQLDERAPMAEPNRREQNGADAEGAKERPPMSASQTNYNIY
LPDNQLEDYLSDVQISKNEMTMLYEDMHLGRMFENLVAKLYYSKRINGFVHLYNGQEAIS
SGIIKNLRPSDFVTSTYRDHVHAISKNVPPRKILNELYGNYYGSTNRGKGGSMHIYSKSE
NFVGGFGFIGEQIPIAVGLAYSILYKREFPQGGAEVRSGAEALSGTEALGGTSSPSGAAP
PLEDADVVACFLGDGTANIGQFFESLNLAATYNLPILFVIENNNWAIGMEGSRSSTDDLQ
NNYSKGKAFNIETYKVDGNDAISIYKLAKKKINQMRRRECGPVLIEAITYRAKGHSLADP
DELRIHEEKASWKKRDPIVHLASYMKKKNIVDESFFEQVKKKTKQILLEAEMDADQNMKK
SQDVNICQLLRDNIFAPSEGAPFQADYHQYATYDPLSDSELGEYYEALRREADRKLHNRK
PDPSEHFASRDLPLLID
NT seq
1494 nt
NT seq
+upstream
nt +downstream
nt
atggtgaagacccatgtcgtggggtccaaaaggttagacgacccaatggtaaagattttt
caactagatgaaagagcccctatggcagaacccaaccgtagagaacaaaacggtgcagac
gctgaaggggctaaggaacgcccccccatgtcggccagccaaaccaactacaacatttac
ctgccagacaaccagctggaggattacctctccgatgtgcaaatcagcaaaaacgaaatg
accatgctgtatgaagatatgcatctggggaggatgttcgaaaatttagtggcaaaacta
tattacagtaaaaggataaacgggttcgtgcatctgtacaatgggcaagaagccatcagc
tctgggattattaaaaatttgaggccctcagattttgtaacgagcacgtatagagaccac
gtgcatgccattagcaaaaatgttcctccgaggaagatccttaatgagctgtatgggaac
tactatggaagcaccaatagggggaagggtggctctatgcacatttacagcaaaagtgaa
aacttcgttgggggcttcggcttcatcggcgagcagatccccatcgcagttgggttggcc
tacagcattttgtacaagcgggagttcccccaggggggggcggaagtccgaagcggggcg
gaagcactaagtgggacggaagccctaggtgggacctcctcaccgagtggagccgccccc
ccgcttgaagacgccgacgtggtggcgtgcttcctgggagacgggacggccaacatcggg
cagttcttcgagtccctgaacctggcggccacgtacaacctgccaatcttgttcgtgata
gaaaacaataactgggcgatcgggatggagggctcaaggagctccaccgatgacctccaa
aacaactactctaagggaaaggccttcaacatagagacttataaagtggacggaaacgat
gccatctcgatttacaaactggcaaagaaaaaaataaatcaaatgagaaggagagagtgt
ggaccggtactcatcgaagcaatcacctaccgagcgaagggacactcccttgcagaccca
gatgaacttagaatacacgaagaaaaagcgtcttggaaaaaaagagatccaattgtacat
ttggctagctacatgaaaaaaaaaaatatcgttgatgagtccttctttgaacaagtcaaa
aaaaaaacgaaacagattctgctggaagctgaaatggacgctgaccaaaatatgaagaag
agccaagatgttaacatctgccaactgttgagggataacatcttcgctccctcggagggg
gcccccttccaggcggattaccaccagtatgccacgtatgaccccctgagtgactccgag
ctgggggagtattacgaggctcttcggcgggaggcggacaggaagctgcacaacaggaag
ccggacccctccgagcacttcgcaagcagggacctccccctgctcatcgattag
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