KEGG Orthology (KO) [BR:pyu00001]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
121024468
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
121024468
09160 Human Diseases
09167 Endocrine and metabolic disease
04934 Cushing syndrome
121024468
09180 Brite Hierarchies
09181 Protein families: metabolism
00199 Cytochrome P450 [BR:pyu00199]
121024468
Enzymes [BR:pyu01000]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.15 With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
1.14.15.4 steroid 11beta-monooxygenase
121024468
Cytochrome P450 [BR:pyu00199]
Cytochrome P450, animal type
CYP11 family
121024468
301 aa
SNLALFGERLGLLGHSPSPASLNFLRALKVMLKSTAQLMFMPRVLSRWTSTQLWKEHFES
WDYIFQYANNAIQKIYQELALSRPEHYSGIVGELLTHADLSLEAIWANSIELTTGSVDTT
VYPVLMTLFELARNPEVQQALRQESLGAEARISQDPQSATSELPLLRAALKETLRLYPVG
MSVDRKVASDVVLQNYHIPAGTLVKVQLYSLGRNPSVFERPECYHPQRWLDNRGSGTRYP
HLAFGFGLRQCLGRRLAETEMLLLLHHVLKSFLVETLRQEDVKMTYQFVFVPSTHPLLTF
R