Puma yagouaroundi (jaguarundi): 121036524 Help Entry 121036524         CDS       T07555                                  Symbol ADCY5 Name (RefSeq) adenylate cyclase type 5   KO K08045   adenylate cyclase 5 [EC:4.6.1.1] Organism pyu  Puma yagouaroundi (jaguarundi) Pathway pyu00230   Purine metabolism pyu01100   Metabolic pathways pyu01522   Endocrine resistance pyu04015   Rap1 signaling pathway pyu04022   cGMP-PKG signaling pathway pyu04024   cAMP signaling pathway pyu04062   Chemokine signaling pathway pyu04072   Phospholipase D signaling pathway pyu04114   Oocyte meiosis pyu04211   Longevity regulating pathway pyu04213   Longevity regulating pathway - multiple species pyu04261   Adrenergic signaling in cardiomyocytes pyu04270   Vascular smooth muscle contraction pyu04371   Apelin signaling pathway pyu04540   Gap junction pyu04611   Platelet activation pyu04713   Circadian entrainment pyu04714   Thermogenesis pyu04723   Retrograde endocannabinoid signaling pyu04724   Glutamatergic synapse pyu04725   Cholinergic synapse pyu04726   Serotonergic synapse pyu04727   GABAergic synapse pyu04728   Dopaminergic synapse pyu04750   Inflammatory mediator regulation of TRP channels pyu04911   Insulin secretion pyu04912   GnRH signaling pathway pyu04913   Ovarian steroidogenesis pyu04914   Progesterone-mediated oocyte maturation pyu04915   Estrogen signaling pathway pyu04916   Melanogenesis pyu04918   Thyroid hormone synthesis pyu04921   Oxytocin signaling pathway pyu04923   Regulation of lipolysis in adipocytes pyu04924   Renin secretion pyu04925   Aldosterone synthesis and secretion pyu04926   Relaxin signaling pathway pyu04927   Cortisol synthesis and secretion pyu04928   Parathyroid hormone synthesis, secretion and action pyu04934   Cushing syndrome pyu04935   Growth hormone synthesis, secretion and action pyu04970   Salivary secretion pyu04971   Gastric acid secretion pyu04972   Pancreatic secretion pyu04976   Bile secretion pyu05012   Parkinson disease pyu05030   Cocaine addiction pyu05031   Amphetamine addiction pyu05032   Morphine addiction pyu05034   Alcoholism pyu05163   Human cytomegalovirus infection pyu05166   Human T-cell leukemia virus 1 infection pyu05200   Pathways in cancer pyu05207   Chemical carcinogenesis - receptor activation pyu05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:pyu00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     121036524 (ADCY5)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     121036524 (ADCY5)    04371 Apelin signaling pathway     121036524 (ADCY5)    04072 Phospholipase D signaling pathway     121036524 (ADCY5)    04024 cAMP signaling pathway     121036524 (ADCY5)    04022 cGMP-PKG signaling pathway     121036524 (ADCY5)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     121036524 (ADCY5)   09144 Cellular community - eukaryotes    04540 Gap junction     121036524 (ADCY5)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     121036524 (ADCY5)    04062 Chemokine signaling pathway     121036524 (ADCY5)   09152 Endocrine system    04911 Insulin secretion     121036524 (ADCY5)    04923 Regulation of lipolysis in adipocytes     121036524 (ADCY5)    04912 GnRH signaling pathway     121036524 (ADCY5)    04913 Ovarian steroidogenesis     121036524 (ADCY5)    04915 Estrogen signaling pathway     121036524 (ADCY5)    04914 Progesterone-mediated oocyte maturation     121036524 (ADCY5)    04921 Oxytocin signaling pathway     121036524 (ADCY5)    04926 Relaxin signaling pathway     121036524 (ADCY5)    04935 Growth hormone synthesis, secretion and action     121036524 (ADCY5)    04918 Thyroid hormone synthesis     121036524 (ADCY5)    04928 Parathyroid hormone synthesis, secretion and action     121036524 (ADCY5)    04916 Melanogenesis     121036524 (ADCY5)    04924 Renin secretion     121036524 (ADCY5)    04925 Aldosterone synthesis and secretion     121036524 (ADCY5)    04927 Cortisol synthesis and secretion     121036524 (ADCY5)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     121036524 (ADCY5)    04270 Vascular smooth muscle contraction     121036524 (ADCY5)   09154 Digestive system    04970 Salivary secretion     121036524 (ADCY5)    04971 Gastric acid secretion     121036524 (ADCY5)    04972 Pancreatic secretion     121036524 (ADCY5)    04976 Bile secretion     121036524 (ADCY5)   09156 Nervous system    04724 Glutamatergic synapse     121036524 (ADCY5)    04727 GABAergic synapse     121036524 (ADCY5)    04725 Cholinergic synapse     121036524 (ADCY5)    04728 Dopaminergic synapse     121036524 (ADCY5)    04726 Serotonergic synapse     121036524 (ADCY5)    04723 Retrograde endocannabinoid signaling     121036524 (ADCY5)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     121036524 (ADCY5)   09149 Aging    04211 Longevity regulating pathway     121036524 (ADCY5)    04213 Longevity regulating pathway - multiple species     121036524 (ADCY5)   09159 Environmental adaptation    04713 Circadian entrainment     121036524 (ADCY5)    04714 Thermogenesis     121036524 (ADCY5)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     121036524 (ADCY5)    05207 Chemical carcinogenesis - receptor activation     121036524 (ADCY5)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     121036524 (ADCY5)    05163 Human cytomegalovirus infection     121036524 (ADCY5)   09164 Neurodegenerative disease    05012 Parkinson disease     121036524 (ADCY5)   09165 Substance dependence    05030 Cocaine addiction     121036524 (ADCY5)    05031 Amphetamine addiction     121036524 (ADCY5)    05032 Morphine addiction     121036524 (ADCY5)    05034 Alcoholism     121036524 (ADCY5)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     121036524 (ADCY5)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     121036524 (ADCY5)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     121036524 (ADCY5) Enzymes [BR:pyu01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      121036524 (ADCY5) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom HNOBA TBK1_ULD GBR2_CC Motif Other DBs NCBI-GeneID:  121036524 NCBI-ProteinID:  XP_040340969 LinkDB All DBs Position Unknown AA seq 931 aa AA seqDB search MLMEPCNAPATSHNTQLHHNITSIPNLFSAGAMDTFSLSSVSSSLPLQLVSNVLIFSCTN IVGVCTHYPAEVSQRQAFQETRECIQARLHSQRENQQQERLLLSVLPRHVAMEMKADINA KQEDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHC LRIKILGDCYYCVSGLPEARADHAHCCVEMGMDMIEAISLVREVTGVNVNMRVGIHSGRV HCGVLGLRKWQFDVWSNDVTLANHMEAGGKAGRIHITKATLNYLNGDYEVEPGCGGERNA YLKEHSIETFLILRCTQKRKEEKAMIAKMNRQRTNSIGHNPPHWGAERPFYNHLGGNQVS KEMKRMGFEDPKDKNAQESANPEDEVDEFLGRAIDARSIDRLRSEHVRKFLLTFREPDLE KKYSKQVDDRFGAYVACASLVFLFICFVQITIVPHSVFMLSFYLTCFLLLTLVVFVSVIY SCVKLFPAPLQTLSRKIVRSKTNSTLVGVFTITLVFLSAFVNMFMCNSKDLFGCLADEHN ISTSQVNACHVVESAVNYSLGDEQGFCSSPRPNCNFPEYFTYSVLLSLLACSVFLQISCI GKLVLMLAIELTYVLIVEVPRVTLFDNADLLVTANAIDFSNNGTSQCPEHATKVALKVVT PIIISVFVLALYLHAQQVESTARLDFLWKLQATEEKEEMEELQAYNRRLLHNILPKDVAA HFLARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEI ISEDRFRQLEKIKTIGSTYMAASGLNDSTYDKVGKTHIKALADFAMKLMDQMKYINEHSF NNFQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPDRIQVTTDMYQVLAA NTYQLECRGVVKVKGKGEMMTYFLNGGPPLS NT seq 2796 nt NT seq  +upstreamnt  +downstreamnt atgcttatggaaccttgcaatgcccctgccacctcccacaatacacagctccatcacaac atcaccagtatccccaaccttttcagcgctggggctatggacacgttcagcctgagctcg gtgtcttcatctctccctctgcagcttgtttccaatgtcctcattttctcctgcaccaac attgtgggtgtctgcacccactacccggctgaggtctctcagagacaggccttccaggaa acccgggagtgcatccaggcacggctccactcacaacgggagaaccagcaacaggagcgg ctcctgctgtctgtcctgccccgtcatgttgccatggagatgaaagcagacatcaatgcc aagcaggaggatatgatgttccataagatttacatccagaaacatgacaacgtgagcatc ctgtttgctgacatcgagggcttcaccagcctggcgtcccagtgcactgcccaggagcta gtcatgaccctcaacgagctcttcgcccgcttcgacaagctggctgcggagaatcactgt ttacgtattaagatcctgggggattgttattactgtgtctctgggctgcctgaagcgagg gctgaccacgctcactgctgcgtggagatgggcatggacatgattgaggccatctcgttg gtccgggaggtgactggggtgaacgtgaacatgcgcgtgggaattcacagcgggcgagta cactgcggtgtccttggtctcaggaagtggcagttcgacgtctggtctaatgacgtcacg ctggccaaccacatggaagctggaggcaaggcagggcgcatccacatcaccaaggccaca ctcaactacctgaatggtgactacgaggtggagccaggctgtgggggcgagcgcaacgcc tacctcaaggagcacagcattgagaccttcctcatcctgcgctgcacccagaagcggaaa gaagaaaaggccatgatcgccaagatgaatcgtcagagaaccaactccattgggcacaac ccgcctcactggggggctgagcgtcccttctataaccacctagggggcaaccaggtgtcc aaggagatgaagcggatgggctttgaagaccccaaggacaagaacgcccaggaaagtgca aaccccgaggatgaagtggacgaatttctgggccgtgccattgacgccaggagcatcgac aggctgcggtctgagcatgtccgcaagttcctcttgaccttcagggagcctgacttagag aagaagtactccaagcaggtggatgaccgatttggtgcctatgtggcatgtgcctcgctt gtcttcctcttcatctgctttgtccagatcaccatcgtgccccactccgtgttcatgttg agtttctacctgacctgtttcctgctgctgaccttggtggtgtttgtgtccgtgatttat tcctgcgtgaagctcttcccggccccgctgcagaccctttccaggaagatcgtgcggtcc aagacgaacagcaccctggtcggagtgttcaccatcaccctggtgttcctgtcggctttt gtcaacatgttcatgtgtaactccaaggacctgtttggctgcctggcggacgagcacaac atcagcaccagccaggtcaacgcgtgccatgtggtggagtcggcagtgaactacagcctg ggtgacgagcagggcttctgcagcagcccccggcccaactgcaacttccccgagtacttc acctacagcgtgctgctcagcctgctggcctgctccgtgttcctgcagatcagctgcatt gggaagctggtgctcatgctggccattgagctcacatatgtgctcattgttgaggtgccc cgcgtcaccctctttgacaacgccgacctgctggtcaccgccaacgccatagacttcagc aacaacgggacctcccagtgccctgagcatgcgaccaaggtggcgctgaaggtggtgacg cccatcatcatctcagtcttcgtgctggccctgtacctgcacgcccagcaagtagagtcc accgcccgcctggacttcctctggaaactgcaggccacggaggaaaaggaggagatggag gagctgcaggcctacaaccggcggctgctgcacaacatcctgcccaaggatgtggccgcc cacttcctggcccgcgagcgacgcaatgatgagctctactaccagtcgtgtgagtgcgtg gccgtcatgttcgcctccatcgccaacttctctgagttctacgttgagctggaggccaac aatgagggtgttgagtgcctgcgactactcaatgagatcatcgccgactttgacgagatc atcagcgaggatcggttcaggcagctggaaaagatcaagaccattggcagcacctacatg gctgcctcaggcctcaatgactctacatatgacaaggtgggcaagacccacatcaaagcc ctggctgactttgccatgaagctcatggaccaaatgaagtacatcaatgagcactccttc aacaacttccagatgaagatcgggctcaatattggccccgtggtggctggggtgatcggg gctcgcaagcctcagtacgacatctggggcaatacggtgaacgtggccagccgcatggac agcaccggtgtgcctgaccgcatccaggtcaccacagacatgtaccaggtgctggctgcc aacacataccagctggagtgcaggggcgtggtcaaggtcaagggcaaaggagagatgatg acctacttcctcaacggtgggcccccgctcagttag

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