Puma yagouaroundi (jaguarundi): 121041241
Help
Entry
121041241 CDS
T07555
Symbol
RAF1
Name
(RefSeq) RAF proto-oncogene serine/threonine-protein kinase isoform X1
KO
K04366
RAF proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
pyu
Puma yagouaroundi (jaguarundi)
Pathway
pyu01521
EGFR tyrosine kinase inhibitor resistance
pyu01522
Endocrine resistance
pyu04010
MAPK signaling pathway
pyu04012
ErbB signaling pathway
pyu04014
Ras signaling pathway
pyu04015
Rap1 signaling pathway
pyu04022
cGMP-PKG signaling pathway
pyu04024
cAMP signaling pathway
pyu04062
Chemokine signaling pathway
pyu04068
FoxO signaling pathway
pyu04071
Sphingolipid signaling pathway
pyu04072
Phospholipase D signaling pathway
pyu04140
Autophagy - animal
pyu04150
mTOR signaling pathway
pyu04151
PI3K-Akt signaling pathway
pyu04210
Apoptosis
pyu04218
Cellular senescence
pyu04270
Vascular smooth muscle contraction
pyu04360
Axon guidance
pyu04370
VEGF signaling pathway
pyu04371
Apelin signaling pathway
pyu04510
Focal adhesion
pyu04540
Gap junction
pyu04550
Signaling pathways regulating pluripotency of stem cells
pyu04613
Neutrophil extracellular trap formation
pyu04625
C-type lectin receptor signaling pathway
pyu04630
JAK-STAT signaling pathway
pyu04650
Natural killer cell mediated cytotoxicity
pyu04660
T cell receptor signaling pathway
pyu04662
B cell receptor signaling pathway
pyu04664
Fc epsilon RI signaling pathway
pyu04666
Fc gamma R-mediated phagocytosis
pyu04720
Long-term potentiation
pyu04722
Neurotrophin signaling pathway
pyu04726
Serotonergic synapse
pyu04730
Long-term depression
pyu04810
Regulation of actin cytoskeleton
pyu04910
Insulin signaling pathway
pyu04912
GnRH signaling pathway
pyu04914
Progesterone-mediated oocyte maturation
pyu04915
Estrogen signaling pathway
pyu04916
Melanogenesis
pyu04917
Prolactin signaling pathway
pyu04919
Thyroid hormone signaling pathway
pyu04921
Oxytocin signaling pathway
pyu04926
Relaxin signaling pathway
pyu04928
Parathyroid hormone synthesis, secretion and action
pyu04929
GnRH secretion
pyu04935
Growth hormone synthesis, secretion and action
pyu05010
Alzheimer disease
pyu05022
Pathways of neurodegeneration - multiple diseases
pyu05034
Alcoholism
pyu05132
Salmonella infection
pyu05152
Tuberculosis
pyu05160
Hepatitis C
pyu05161
Hepatitis B
pyu05163
Human cytomegalovirus infection
pyu05164
Influenza A
pyu05165
Human papillomavirus infection
pyu05167
Kaposi sarcoma-associated herpesvirus infection
pyu05170
Human immunodeficiency virus 1 infection
pyu05200
Pathways in cancer
pyu05205
Proteoglycans in cancer
pyu05206
MicroRNAs in cancer
pyu05207
Chemical carcinogenesis - receptor activation
pyu05208
Chemical carcinogenesis - reactive oxygen species
pyu05210
Colorectal cancer
pyu05211
Renal cell carcinoma
pyu05212
Pancreatic cancer
pyu05213
Endometrial cancer
pyu05214
Glioma
pyu05215
Prostate cancer
pyu05218
Melanoma
pyu05219
Bladder cancer
pyu05220
Chronic myeloid leukemia
pyu05221
Acute myeloid leukemia
pyu05223
Non-small cell lung cancer
pyu05224
Breast cancer
pyu05225
Hepatocellular carcinoma
pyu05226
Gastric cancer
pyu05230
Central carbon metabolism in cancer
pyu05231
Choline metabolism in cancer
pyu05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
pyu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
121041241 (RAF1)
04012 ErbB signaling pathway
121041241 (RAF1)
04014 Ras signaling pathway
121041241 (RAF1)
04015 Rap1 signaling pathway
121041241 (RAF1)
04370 VEGF signaling pathway
121041241 (RAF1)
04371 Apelin signaling pathway
121041241 (RAF1)
04630 JAK-STAT signaling pathway
121041241 (RAF1)
04068 FoxO signaling pathway
121041241 (RAF1)
04072 Phospholipase D signaling pathway
121041241 (RAF1)
04071 Sphingolipid signaling pathway
121041241 (RAF1)
04024 cAMP signaling pathway
121041241 (RAF1)
04022 cGMP-PKG signaling pathway
121041241 (RAF1)
04151 PI3K-Akt signaling pathway
121041241 (RAF1)
04150 mTOR signaling pathway
121041241 (RAF1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
121041241 (RAF1)
09143 Cell growth and death
04210 Apoptosis
121041241 (RAF1)
04218 Cellular senescence
121041241 (RAF1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
121041241 (RAF1)
04540 Gap junction
121041241 (RAF1)
04550 Signaling pathways regulating pluripotency of stem cells
121041241 (RAF1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
121041241 (RAF1)
09150 Organismal Systems
09151 Immune system
04613 Neutrophil extracellular trap formation
121041241 (RAF1)
04625 C-type lectin receptor signaling pathway
121041241 (RAF1)
04650 Natural killer cell mediated cytotoxicity
121041241 (RAF1)
04660 T cell receptor signaling pathway
121041241 (RAF1)
04662 B cell receptor signaling pathway
121041241 (RAF1)
04664 Fc epsilon RI signaling pathway
121041241 (RAF1)
04666 Fc gamma R-mediated phagocytosis
121041241 (RAF1)
04062 Chemokine signaling pathway
121041241 (RAF1)
09152 Endocrine system
04910 Insulin signaling pathway
121041241 (RAF1)
04929 GnRH secretion
121041241 (RAF1)
04912 GnRH signaling pathway
121041241 (RAF1)
04915 Estrogen signaling pathway
121041241 (RAF1)
04914 Progesterone-mediated oocyte maturation
121041241 (RAF1)
04917 Prolactin signaling pathway
121041241 (RAF1)
04921 Oxytocin signaling pathway
121041241 (RAF1)
04926 Relaxin signaling pathway
121041241 (RAF1)
04935 Growth hormone synthesis, secretion and action
121041241 (RAF1)
04919 Thyroid hormone signaling pathway
121041241 (RAF1)
04928 Parathyroid hormone synthesis, secretion and action
121041241 (RAF1)
04916 Melanogenesis
121041241 (RAF1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
121041241 (RAF1)
09156 Nervous system
04726 Serotonergic synapse
121041241 (RAF1)
04720 Long-term potentiation
121041241 (RAF1)
04730 Long-term depression
121041241 (RAF1)
04722 Neurotrophin signaling pathway
121041241 (RAF1)
09158 Development and regeneration
04360 Axon guidance
121041241 (RAF1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
121041241 (RAF1)
05206 MicroRNAs in cancer
121041241 (RAF1)
05205 Proteoglycans in cancer
121041241 (RAF1)
05207 Chemical carcinogenesis - receptor activation
121041241 (RAF1)
05208 Chemical carcinogenesis - reactive oxygen species
121041241 (RAF1)
05230 Central carbon metabolism in cancer
121041241 (RAF1)
05231 Choline metabolism in cancer
121041241 (RAF1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
121041241 (RAF1)
09162 Cancer: specific types
05210 Colorectal cancer
121041241 (RAF1)
05212 Pancreatic cancer
121041241 (RAF1)
05225 Hepatocellular carcinoma
121041241 (RAF1)
05226 Gastric cancer
121041241 (RAF1)
05214 Glioma
121041241 (RAF1)
05221 Acute myeloid leukemia
121041241 (RAF1)
05220 Chronic myeloid leukemia
121041241 (RAF1)
05218 Melanoma
121041241 (RAF1)
05211 Renal cell carcinoma
121041241 (RAF1)
05219 Bladder cancer
121041241 (RAF1)
05215 Prostate cancer
121041241 (RAF1)
05213 Endometrial cancer
121041241 (RAF1)
05224 Breast cancer
121041241 (RAF1)
05223 Non-small cell lung cancer
121041241 (RAF1)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
121041241 (RAF1)
05161 Hepatitis B
121041241 (RAF1)
05160 Hepatitis C
121041241 (RAF1)
05164 Influenza A
121041241 (RAF1)
05163 Human cytomegalovirus infection
121041241 (RAF1)
05167 Kaposi sarcoma-associated herpesvirus infection
121041241 (RAF1)
05165 Human papillomavirus infection
121041241 (RAF1)
09171 Infectious disease: bacterial
05132 Salmonella infection
121041241 (RAF1)
05152 Tuberculosis
121041241 (RAF1)
09164 Neurodegenerative disease
05010 Alzheimer disease
121041241 (RAF1)
05022 Pathways of neurodegeneration - multiple diseases
121041241 (RAF1)
09165 Substance dependence
05034 Alcoholism
121041241 (RAF1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
121041241 (RAF1)
01522 Endocrine resistance
121041241 (RAF1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pyu01001
]
121041241 (RAF1)
Enzymes [BR:
pyu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
121041241 (RAF1)
Protein kinases [BR:
pyu01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
121041241 (RAF1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
RBD
C1_1
Kinase-like
ABC1
zf-RING-like
Pkinase_fungal
C1_2
Motif
Other DBs
NCBI-GeneID:
121041241
NCBI-ProteinID:
XP_040347862
LinkDB
All DBs
Position
Unknown
AA seq
668 aa
AA seq
DB search
MEHIQGAWKTISNGFGFKDAVFDGPSCISPTIVQPFGFQRRASDDGKLTDSSKTSNTIRV
FLPNKQRTVVNVRNGMSLHDCLMKALKVRGLQPECCAVFRLLHEHKGKKARLDWNTDATS
LIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKV
PTMCVDWSNIRQLLLFPNSPIGDSGVPALPSLTMRRMRESVSRMPVSSQHRYSTPHAFTF
NSSSPSSEGSLSQRQRSTSTPNVHMVSTTLPVDSRMIENNSLNASPRAWSRRFCLRGRDA
IRSHSESASPSALSSSPNNLSPTGWSQPKTPVPAHRERAPGSGTQEKNKIRPRGQRDSSY
YWEIEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKT
RHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLH
AKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQ
DNNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKA
MKRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEPSLHRAAHTEDINACTLT
TSPRLPVF
NT seq
2007 nt
NT seq
+upstream
nt +downstream
nt
atggagcacatacaaggggcctggaagacgatcagcaatggctttggattcaaagatgca
gtgtttgatggccccagctgcatctcccctacaatagttcagccatttggctttcagcgt
cgggcatcagatgatggcaaacttacggactcttctaagacaagcaacactatccgtgtt
ttcttgccaaacaagcaaagaacagtggtcaatgtgagaaatggaatgagcttgcatgat
tgccttatgaaagcactcaaggtgaggggcctgcagccggagtgctgtgcagtgttcaga
cttctccatgaacataaaggtaaaaaagcgcgtttagattggaatactgatgccacctcg
ttgattggagaagaacttcaagtagatttcctggatcacgttcccctcacaacacacaac
tttgctcggaagaccttcctgaagcttgccttctgtgacatctgtcagaagttcctgcta
aatggatttcgatgtcagacttgtggctacaaatttcatgagcactgtagcaccaaagta
cctactatgtgtgtggactggagtaatatcagacaactcttattgttcccaaattctcct
attggtgatagtggggtcccagcactgccttctttgacaatgcgtcggatgcgagagtct
gtttcccggatgcctgttagttcccagcacagatactccacaccccacgccttcacgttc
aactcttccagcccttcctctgaaggttccctctcccagaggcagagatcaacatccaca
cctaatgtccacatggtcagcaccaccctgcctgtggacagcaggatgattgagaataac
agcctgaatgcttctcccagggcgtggtccagacgattttgtttgaggggaagagatgca
attcgaagccacagtgaatcagcctcaccttcagccttgtccagcagccctaacaatctg
agcccaacgggctggtcacagcccaaaacccctgtgccagcacacagagagagggcacca
ggatccgggacccaggagaaaaacaaaatcaggcctcgtggacagagagattcaagctat
tactgggaaatagaagccagcgaagtgatgctttccactcggattggatcaggctcattt
ggaacggtgtataagggcaagtggcatggagatgttgcagtgaaaattctaaaagttgtc
gaccccacgccagagcagttccaggccttcaggaatgaggtggctgtcctacgcaaaaca
cggcacgtgaacatcctgctcttcatgggctacatgacaaaggacaacctggcaattgtg
acccagtggtgcgagggcagcagcctctacaaacacctgcatgtccaggagactaagttc
cagatgttccagttgattgacatcgcccgccagactgctcagggaatggactatttgcat
gcaaagaatatcatccacagagacatgaaatccaacaatatatttctccatgaaggcctg
acggtgaaaattggagattttggtttggcaacagtaaagtcgcgctggagcggttctcag
caggtcgaacaacccactggctctgtcctgtggatggcccccgaggtgatccgaatgcag
gataataacccattcagcttccagtctgatgtctactcctacggcattgtgctctatgag
ctcatgacaggggagcttccttactcccacatcaataaccgcgaccagatcatcttcatg
gtgggccgaggatatgcctccccagacctcagtaagctatataagaactgccccaaagca
atgaagaggcttgtagctgactgtgtgaagaaggttaaggaagagaggcctctttttccc
cagatcctgtcttccatcgagcttctccaacactctctgccgaaaatcaaccggagtgct
tctgagccatccctgcaccgggcggcccacactgaggatatcaacgcctgcacgttgacc
acatcccctagactgcctgtcttctag
DBGET
integrated database retrieval system