Rousettus aegyptiacus (Egyptian rousette): 107510629
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Entry
107510629 CDS
T06036
Symbol
PDHA2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
ray
Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray00010
Glycolysis / Gluconeogenesis
ray00020
Citrate cycle (TCA cycle)
ray00620
Pyruvate metabolism
ray00785
Lipoic acid metabolism
ray01100
Metabolic pathways
ray01200
Carbon metabolism
ray01210
2-Oxocarboxylic acid metabolism
ray04066
HIF-1 signaling pathway
ray04922
Glucagon signaling pathway
ray05230
Central carbon metabolism in cancer
ray05415
Diabetic cardiomyopathy
Module
ray_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ray00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
107510629 (PDHA2)
00020 Citrate cycle (TCA cycle)
107510629 (PDHA2)
00620 Pyruvate metabolism
107510629 (PDHA2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
107510629 (PDHA2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
107510629 (PDHA2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
107510629 (PDHA2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
107510629 (PDHA2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
107510629 (PDHA2)
Enzymes [BR:
ray01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
107510629 (PDHA2)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
107510629
NCBI-ProteinID:
XP_015999794
UniProt:
A0A7J8E9F1
LinkDB
All DBs
Position
Unknown
AA seq
391 aa
AA seq
DB search
MRKMLVAAVSRVLSDVAQKPASRVLVASCNFSNDATFEIKKCDLYRLEEGPPVTTVLTRE
DGLKYYKMMQTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGIEAGINPTDHVITSYR
AHGLCYTRGLSARSILAELTGRRGGCAKGKGGSMHMYSKNFYGGNGIVGAQGPLGAGIAL
ACKYKENNEVSLTLYGDGAANQGQIHEAFNMAALWKLPCVFICENNRYGMGTAVERAAAS
TDYYKRGSVIPGLRVDGMDVLCVREATKFATDYCRSGKGPILMELQTYRYHGHSMSDPGV
SYRSREEIHDVRSKSDPIMLLKNKMVNNKLASIEELKEIDVEVRKEIEDAAQFATTDPEP
PLEEIGHHIYSDSPPFEVRGANQWIKFKSIS
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgttgccgctgtgtcccgcgtgttgtcggatgtcgcccagaagcct
gctagcagagtgctggtggcttcctgtaacttttcaaacgatgccacatttgaaattaag
aaatgtgatctttataggttggaagaaggtccccctgtcacaacagtgctcacccgggag
gatggactgaaatactacaagatgatgcagactgttcgccgaatggaattgaaggcagat
cagctgtataaacagaaattcattcgtggtttctgtcacttgtgtgatggtcaggaagct
tgttgcgtgggcattgaggctgggataaatcccaccgatcatgtcatcacatcctatcgg
gctcatggcttatgctatactcgtggactgtctgcccgatcaattcttgcagagctgaca
ggacgacgaggaggttgtgctaaaggtaaaggaggatcgatgcatatgtattccaagaac
ttctacgggggcaatggcattgtgggtgctcagggacccctgggagcaggcattgctctg
gcctgtaaatacaaggaaaacaatgaggtctctttgaccctgtacggagatggtgctgct
aatcagggtcagatacatgaagctttcaacatggcagctttgtggaaattaccgtgtgtt
ttcatctgtgagaataaccgctatggaatgggaacagccgttgagagagcagcagccagc
acggattactacaagagaggcagtgttatccctggactaagggtggacggaatggatgtt
ctgtgtgttcgggaggcaactaagtttgcaactgactattgtagatctggaaaggggccc
attctgatggagcttcagacttaccgttaccatggacacagcatgagtgatcctggagtc
agttatcgttcacgagaagaaattcatgatgtaagaagtaaaagtgatcctattatgctt
ctgaaaaataaaatggtaaacaacaagcttgccagtattgaagaactgaaggaaattgat
gttgaagtgagaaaagaaattgaagatgcagcccagtttgctacaactgatcctgaacca
cctttggaagaaataggtcatcacatatacagcgatagtccaccttttgaagttcgtggt
gcgaatcagtggatcaagtttaagtctatcagttaa
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