Rhodothermaceae bacterium RA: AWN76_014170
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Entry
AWN76_014170 CDS
T04780
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
rbar
Rhodothermaceae bacterium RA
Pathway
rbar00790
Folate biosynthesis
rbar01100
Metabolic pathways
rbar01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
rbar00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
AWN76_014170
Enzymes [BR:
rbar01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
AWN76_014170
6.3.2.17 tetrahydrofolate synthase
AWN76_014170
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
ARA94187
UniProt:
A0A1V0DH58
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Position
complement(3519903..3521216)
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AA seq
437 aa
AA seq
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MNAVDYLHRLPRFAEQGAAAFRPGLERMDALLTAMGRPHEHFASVHVAGTNGKGSTASML
AAIGTATGRRIGLHTSPHLVHLTERMRIDGVPAPTAWLEEAVARYRDVFDAVRPSFFEAT
VALSFRYFADAGVDLAVVEVGLGGRLDATNVLRPVLCLITSIGLDHTDLLGDTLPAIAAE
KAGIIKPGVPVFTSATQPEVLGVLRRVAATQKAPFHALSDEVRTTPGAARPDHQYLSLCT
PQGDYPDLRLDLAGRHQHHNAALAVRAAEQVFAPLSPEAVRTGLRDVRRLAGLRGRLEVL
STAPLVVADVAHNADGLAQALAFVRQHRGTGRLYVVLGWMRDKDLDPAAALLAEAQATVF
PVDLDSPRAFPAASLGAHLRAQGLATAGGGRVPDGLAWFQRHATPADILLVTGSHQVVEA
LLRSEAAPGKAARPESS
NT seq
1314 nt
NT seq
+upstream
nt +downstream
nt
atgaacgccgtcgactacctccaccgtctgccccggtttgccgagcagggcgcggctgcc
ttccggccgggcctggaacgcatggacgcgctgctcacggcgatgggacgcccgcacgag
cactttgccagcgtccacgtggccggcaccaacggcaagggctcgacggcctcgatgctg
gccgccatcggcacggcgacgggccgccgcatcggactccacacgtccccgcacctggtc
cacctcaccgagcggatgcggatcgacggcgtgccggcccccaccgcctggctggaggag
gccgtcgcccgttaccgggacgtcttcgacgccgtacggccgagcttcttcgaggccacc
gtcgccctcagcttccgatacttcgccgacgccggcgtcgacctcgccgtggtggaagtg
ggcctcggcgggcggctggatgccacgaacgtgctgcgccccgtcctctgcctgatcacc
agcatcgggctggaccatacggacctgctcggcgacacgctccccgccatcgccgccgag
aaggccggcatcatcaagccgggcgtccccgtcttcacctcggccacgcagcccgaagtg
ctgggcgtgctgcggcgcgtggcggcgacgcagaaggccccgtttcatgccctgtccgac
gaggtgcggacgaccccgggcgccgcccggcccgatcaccagtacctgagcctttgcacg
ccgcagggcgactacccggacctgcggctcgacctcgcgggccggcatcagcaccacaac
gccgcgctggccgtccgcgccgccgagcaggtcttcgctccgctgtccccggaagccgtc
cgcaccggcctccgcgacgtgcggcggctggccggtctccggggccgcctggaggtcctg
tccaccgctcccctggtcgtcgccgacgtcgcccacaacgccgacgggctggcgcaggcg
ctggccttcgtccggcagcaccggggcaccggacggctctacgtcgtcctgggctggatg
cgcgacaaggacctggacccggccgccgccctgctcgccgaggcccaggccaccgtcttt
cccgtcgacctggactccccccgcgccttcccggcggcctcgctgggcgcccacctgcgc
gcgcagggcctagccacggcaggtggagggcgcgtacccgacggcctcgcctggtttcag
cgccacgccaccccggccgatatcttgctcgtgaccgggtcccaccaggtcgtggaggcg
ctgctgcggagcgaagcggcccccgggaaggccgccaggccggaaagttcatga
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