Rhinopithecus bieti (black snub-nosed monkey): 108522031
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Entry
108522031 CDS
T04641
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
rbb
Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb00010
Glycolysis / Gluconeogenesis
rbb00020
Citrate cycle (TCA cycle)
rbb00620
Pyruvate metabolism
rbb00785
Lipoic acid metabolism
rbb01100
Metabolic pathways
rbb01200
Carbon metabolism
rbb01210
2-Oxocarboxylic acid metabolism
rbb04066
HIF-1 signaling pathway
rbb04922
Glucagon signaling pathway
rbb05230
Central carbon metabolism in cancer
rbb05415
Diabetic cardiomyopathy
Module
rbb_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
rbb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
108522031 (PDHA1)
00020 Citrate cycle (TCA cycle)
108522031 (PDHA1)
00620 Pyruvate metabolism
108522031 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
108522031 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
108522031 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
108522031 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
108522031 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
108522031 (PDHA1)
Enzymes [BR:
rbb01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
108522031 (PDHA1)
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Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
DUF1117
Motif
Other DBs
NCBI-GeneID:
108522031
NCBI-ProteinID:
XP_017717619
LinkDB
All DBs
Position
Unknown
AA seq
426 aa
AA seq
DB search
MTLSRRAATEAWRLLGHLKETLGHPRRASWAVRSRRCRQCLCFMRKMLAAVSRVLSGASQ
KPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELK
ADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAE
LTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDG
AANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGM
DILCVREATKFAAAYCRSGKVRLVLTDRLLLFPPHSYRTREEIQEVRSKSDPIMLLKDRM
VNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPPLEELGYHIYSSDPPFEVRGANQWI
KFKSVS
NT seq
1281 nt
NT seq
+upstream
nt +downstream
nt
atgactctgtcacgtcgcgctgcgactgaggcgtggcgtctgctggggcacctgaaggag
actttgggacacccgcgtcgtgcctcttgggctgtgaggagtcgccgctgccgccagtgc
ctgtgcttcatgaggaagatgctcgccgccgtctcccgcgtgttgtctggcgcttctcag
aagccggcaagcagagtgctggtagcatcccgtaattttgcaaatgatgccacatttgaa
attaagaaatgtgaccttcaccgactggaagaaggccctcctgtcacaacagtgctcacc
agggaggatgggctcaaatactacaggatgatgcagactgtgcgccgaatggagttgaaa
gcagatcagctgtataaacagaaaattattcgtggtttctgtcacttgtgtgatggtcag
gaagcttgctgtgtgggcctggaagccggcatcaaccccacagaccatctcataacagcc
taccgggctcacggctttaccttcacccggggcctttctgtccgagaaattctcgcagag
cttacaggacgaaaaggaggttgtgctaaagggaaaggaggatcgatgcacatgtatgcc
aagaacttctacgggggcaatggcatcgtgggagcgcaggtgcccctgggcgctgggatt
gctctagcctgtaagtataatggaaaagatgaggtctgcctgactttatatggcgatggt
gctgctaaccagggccagatattcgaagcttacaacatggcagctttgtggaaattacct
tgtattttcatctgtgagaataatcgctatggaatgggaacatctgttgagagagcagca
gccagcactgattactacaagagaggcgatttcattcctgggctgagagtggatggaatg
gatatcctgtgcgtccgagaggcgacaaagtttgctgctgcctattgtagatctgggaag
gtaaggcttgttcttactgatcgattactacttttccctccccatagttaccgtacacga
gaagaaattcaggaagtaagaagtaagagtgaccctattatgcttctcaaggacaggatg
gtgaacagcaatcttgccagtgtggaagaactaaaggaaattgatgtggaagtgaggaag
gagattgaggatgctgcccagtttgccacggccgatcctgagccacctttggaggagctg
ggctaccacatctactccagtgacccacctttcgaagttcgtggtgccaatcagtggatc
aagtttaagtcagtcagttaa
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