Rhinopithecus bieti (black snub-nosed monkey): 108539403
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Entry
108539403 CDS
T04641
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12 isoform X1
KO
K04441
p38 MAP kinase [EC:
2.7.11.24
]
Organism
rbb
Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb01522
Endocrine resistance
rbb04010
MAPK signaling pathway
rbb04015
Rap1 signaling pathway
rbb04068
FoxO signaling pathway
rbb04071
Sphingolipid signaling pathway
rbb04114
Oocyte meiosis
rbb04148
Efferocytosis
rbb04218
Cellular senescence
rbb04261
Adrenergic signaling in cardiomyocytes
rbb04370
VEGF signaling pathway
rbb04380
Osteoclast differentiation
rbb04550
Signaling pathways regulating pluripotency of stem cells
rbb04611
Platelet activation
rbb04613
Neutrophil extracellular trap formation
rbb04620
Toll-like receptor signaling pathway
rbb04621
NOD-like receptor signaling pathway
rbb04622
RIG-I-like receptor signaling pathway
rbb04625
C-type lectin receptor signaling pathway
rbb04657
IL-17 signaling pathway
rbb04658
Th1 and Th2 cell differentiation
rbb04659
Th17 cell differentiation
rbb04660
T cell receptor signaling pathway
rbb04664
Fc epsilon RI signaling pathway
rbb04668
TNF signaling pathway
rbb04670
Leukocyte transendothelial migration
rbb04714
Thermogenesis
rbb04722
Neurotrophin signaling pathway
rbb04723
Retrograde endocannabinoid signaling
rbb04728
Dopaminergic synapse
rbb04750
Inflammatory mediator regulation of TRP channels
rbb04912
GnRH signaling pathway
rbb04914
Progesterone-mediated oocyte maturation
rbb04917
Prolactin signaling pathway
rbb04926
Relaxin signaling pathway
rbb04932
Non-alcoholic fatty liver disease
rbb04933
AGE-RAGE signaling pathway in diabetic complications
rbb04935
Growth hormone synthesis, secretion and action
rbb04936
Alcoholic liver disease
rbb05014
Amyotrophic lateral sclerosis
rbb05020
Prion disease
rbb05022
Pathways of neurodegeneration - multiple diseases
rbb05132
Salmonella infection
rbb05133
Pertussis
rbb05135
Yersinia infection
rbb05140
Leishmaniasis
rbb05142
Chagas disease
rbb05145
Toxoplasmosis
rbb05152
Tuberculosis
rbb05161
Hepatitis B
rbb05163
Human cytomegalovirus infection
rbb05167
Kaposi sarcoma-associated herpesvirus infection
rbb05169
Epstein-Barr virus infection
rbb05170
Human immunodeficiency virus 1 infection
rbb05171
Coronavirus disease - COVID-19
rbb05205
Proteoglycans in cancer
rbb05208
Chemical carcinogenesis - reactive oxygen species
rbb05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
rbb05415
Diabetic cardiomyopathy
rbb05417
Lipid and atherosclerosis
rbb05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
rbb00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
108539403 (MAPK12)
04015 Rap1 signaling pathway
108539403 (MAPK12)
04370 VEGF signaling pathway
108539403 (MAPK12)
04668 TNF signaling pathway
108539403 (MAPK12)
04068 FoxO signaling pathway
108539403 (MAPK12)
04071 Sphingolipid signaling pathway
108539403 (MAPK12)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
108539403 (MAPK12)
09143 Cell growth and death
04114 Oocyte meiosis
108539403 (MAPK12)
04218 Cellular senescence
108539403 (MAPK12)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
108539403 (MAPK12)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
108539403 (MAPK12)
04613 Neutrophil extracellular trap formation
108539403 (MAPK12)
04620 Toll-like receptor signaling pathway
108539403 (MAPK12)
04621 NOD-like receptor signaling pathway
108539403 (MAPK12)
04622 RIG-I-like receptor signaling pathway
108539403 (MAPK12)
04625 C-type lectin receptor signaling pathway
108539403 (MAPK12)
04660 T cell receptor signaling pathway
108539403 (MAPK12)
04658 Th1 and Th2 cell differentiation
108539403 (MAPK12)
04659 Th17 cell differentiation
108539403 (MAPK12)
04657 IL-17 signaling pathway
108539403 (MAPK12)
04664 Fc epsilon RI signaling pathway
108539403 (MAPK12)
04670 Leukocyte transendothelial migration
108539403 (MAPK12)
09152 Endocrine system
04912 GnRH signaling pathway
108539403 (MAPK12)
04914 Progesterone-mediated oocyte maturation
108539403 (MAPK12)
04917 Prolactin signaling pathway
108539403 (MAPK12)
04926 Relaxin signaling pathway
108539403 (MAPK12)
04935 Growth hormone synthesis, secretion and action
108539403 (MAPK12)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
108539403 (MAPK12)
09156 Nervous system
04728 Dopaminergic synapse
108539403 (MAPK12)
04723 Retrograde endocannabinoid signaling
108539403 (MAPK12)
04722 Neurotrophin signaling pathway
108539403 (MAPK12)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
108539403 (MAPK12)
09158 Development and regeneration
04380 Osteoclast differentiation
108539403 (MAPK12)
09159 Environmental adaptation
04714 Thermogenesis
108539403 (MAPK12)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
108539403 (MAPK12)
05208 Chemical carcinogenesis - reactive oxygen species
108539403 (MAPK12)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
108539403 (MAPK12)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
108539403 (MAPK12)
05161 Hepatitis B
108539403 (MAPK12)
05171 Coronavirus disease - COVID-19
108539403 (MAPK12)
05163 Human cytomegalovirus infection
108539403 (MAPK12)
05167 Kaposi sarcoma-associated herpesvirus infection
108539403 (MAPK12)
05169 Epstein-Barr virus infection
108539403 (MAPK12)
09171 Infectious disease: bacterial
05132 Salmonella infection
108539403 (MAPK12)
05135 Yersinia infection
108539403 (MAPK12)
05133 Pertussis
108539403 (MAPK12)
05152 Tuberculosis
108539403 (MAPK12)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
108539403 (MAPK12)
05140 Leishmaniasis
108539403 (MAPK12)
05142 Chagas disease
108539403 (MAPK12)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
108539403 (MAPK12)
05020 Prion disease
108539403 (MAPK12)
05022 Pathways of neurodegeneration - multiple diseases
108539403 (MAPK12)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
108539403 (MAPK12)
05418 Fluid shear stress and atherosclerosis
108539403 (MAPK12)
05415 Diabetic cardiomyopathy
108539403 (MAPK12)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
108539403 (MAPK12)
04932 Non-alcoholic fatty liver disease
108539403 (MAPK12)
04933 AGE-RAGE signaling pathway in diabetic complications
108539403 (MAPK12)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
108539403 (MAPK12)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rbb01001
]
108539403 (MAPK12)
Enzymes [BR:
rbb01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
108539403 (MAPK12)
Protein kinases [BR:
rbb01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
108539403 (MAPK12)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
Motif
Other DBs
NCBI-GeneID:
108539403
NCBI-ProteinID:
XP_017743539
LinkDB
All DBs
Position
Unknown
AA seq
419 aa
AA seq
DB search
MSSPPPARSGFYRRGGDARRPGRGGAAVYRDLQPLGRGQPHRRQGGHQEAVSALPVRAVR
QARLPRAAPAQTHASREQLLQASLGPCHPKMLRQQLSHDLSTVHLPNQGCCGDQVIGLLD
VFTPDETLDDFTDFYLVMPFMGTDLGKLMKHEKLGEDRIQFLVYQMLKGLRYIHAAGIIH
RVSPGGGASHQPSPSAIPCLHVLPDLKPGNLAVNEDCELKILDFGLARQADSEMTGYVVT
RWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMKVTGTPPAE
FVQRLQSDEAKNYMKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAEQRVTAAEALAH
PYFESLHDTEDEPQVQKYDDSFDDVDRTLDEWKRVTYKEVLSFKPPRQLGARVSKETAL
NT seq
1260 nt
NT seq
+upstream
nt +downstream
nt
atgagctctccgccgcctgcccgcagtggcttttaccgccgaggaggtgacgcaagacgg
cctgggaggggtggcgcggccgtgtaccgggacctgcagccgctcggccgtggacagccg
caccggcgccaaggtggccatcaagaagctgtatcggcccttccagtccgagctgttcgc
caagcgcgcctaccgcgagctgcgcctgctcaaacacatgcgtcacgagaacaactcctc
caggcctccctgggaccctgtcaccccaaaatgctgaggcagcagttatcacatgaccta
tccactgtccatctccccaaccaggggtgctgtggggaccaggtgattgggctgctggac
gtattcactcctgatgagaccctggatgacttcacagacttttacctggtgatgccattc
atgggcaccgacctgggcaagctcatgaaacatgagaagctgggcgaggaccggatccag
ttcctcgtgtaccagatgctgaaggggttgaggtatatccatgctgccggcatcatccac
agagtgagtcctggtggaggagccagccatcagccctcccccagcgcaatcccctgcctc
cacgtcctacctgacctgaagcctggcaacctggctgtgaacgaagactgtgagctgaag
atcctggactttggcctggccaggcaagcagacagtgagatgactgggtatgtggtgacc
cggtggtaccgggcacccgaggtcatcttgaattggatgcgctacacgcagacggtggac
atctggtctgtgggctgcatcatggcggagatgatcacaggcaagacgctgttcaagggc
agcgaccacctggaccagctgaaggagatcatgaaggtgacagggacgcctccagctgag
tttgtgcagcggctgcagagtgatgaggccaagaactacatgaagggcctccccgagttg
gagaagaaggattttgcctccatcctgaccaatgcaagccctctggctgtgaacctcctg
gagaagatgctggtgctggatgcggagcagcgggtgacagcagccgaggcactggcccat
ccctacttcgagtccctgcacgacacagaagatgagccccaggtccagaagtatgacgac
tcctttgatgacgtggaccgcacgctggatgaatggaagcgtgttacttacaaagaggtg
ctcagcttcaagcctccccggcagctgggagccagggtctccaaggagacggctctgtga
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